Jeffrey Van Haren

TitleAssociate Specialist
InstitutionUniversity of California San Francisco
DepartmentCell and Tissue Biology
Address513 Parnassus Ave
San Francisco CA 94143
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    1. van Haren J, Charafeddine RA, Ettinger A, Wang H, Hahn KM, Wittmann T. Local control of intracellular microtubule dynamics by EB1 photodissociation. Nat Cell Biol. 2018 Mar; 20(3):252-261. PMID: 29379139.
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    2. Pemble H, Kumar P, van Haren J, Wittmann T. GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics. J Cell Sci. 2017 04 15; 130(8):1404-1412. PMID: 28232523.
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    3. Ettinger A, van Haren J, Ribeiro SA, Wittmann T. Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice. Curr Biol. 2016 06 20; 26(12):1549-1555. PMID: 27238282.
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    4. van Haren J, Boudeau J, Schmidt S, Basu S, Liu Z, Lammers D, Demmers J, Benhari J, Grosveld F, Debant A, Galjart N. Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension. Curr Biol. 2014 Aug 04; 24(15):1778-85. PMID: 25065758.
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    5. Ruiz-Saenz A, van Haren J, Sayas CL, Rangel L, Demmers J, Millán J, Alonso MA, Galjart N, Correas I. Protein 4.1R binds to CLASP2 and regulates dynamics, organization and attachment of microtubules to the cell cortex. J Cell Sci. 2013 Oct 15; 126(Pt 20):4589-601. PMID: 23943871.
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    6. Ghamari A, van de Corput MP, Thongjuea S, van Cappellen WA, van Ijcken W, van Haren J, Soler E, Eick D, Lenhard B, Grosveld FG. In vivo live imaging of RNA polymerase II transcription factories in primary cells. Genes Dev. 2013 Apr 01; 27(7):767-77. PMID: 23592796; PMCID: PMC3639417.
    7. Drabek K, Gutiérrez L, Vermeij M, Clapes T, Patel SR, Boisset JC, van Haren J, Pereira AL, Liu Z, Akinci U, Nikolic T, van Ijcken W, van den Hout M, Meinders M, Melo C, Sambade C, Drabek D, Hendriks RW, Philipsen S, Mommaas M, Grosveld F, Maiato H, Italiano JE, Robin C, Galjart N. The microtubule plus-end tracking protein CLASP2 is required for hematopoiesis and hematopoietic stem cell maintenance. Cell Rep. 2012 Oct 25; 2(4):781-8. PMID: 23084744.
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    8. Schmidt N, Basu S, Sladecek S, Gatti S, van Haren J, Treves S, Pielage J, Galjart N, Brenner HR. Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane. J Cell Biol. 2012 Aug 06; 198(3):421-37. PMID: 22851317; PMCID: PMC3413356.
    9. Lee HS, Komarova YA, Nadezhdina ES, Anjum R, Peloquin JG, Schober JM, Danciu O, van Haren J, Galjart N, Gygi SP, Akhmanova A, Borisy GG. Phosphorylation controls autoinhibition of cytoplasmic linker protein-170. Mol Biol Cell. 2010 Aug 01; 21(15):2661-73. PMID: 20519438; PMCID: PMC2912352.
    10. Stepanova T, Smal I, van Haren J, Akinci U, Liu Z, Miedema M, Limpens R, van Ham M, van der Reijden M, Poot R, Grosveld F, Mommaas M, Meijering E, Galjart N. History-dependent catastrophes regulate axonal microtubule behavior. Curr Biol. 2010 Jun 08; 20(11):1023-8. PMID: 20471267.
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    11. van Haren J, Draegestein K, Keijzer N, Abrahams JP, Grosveld F, Peeters PJ, Moechars D, Galjart N. Mammalian Navigators are microtubule plus-end tracking proteins that can reorganize the cytoskeleton to induce neurite-like extensions. Cell Motil Cytoskeleton. 2009 Oct; 66(10):824-38. PMID: 19396870.
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    12. Dragestein KA, van Cappellen WA, van Haren J, Tsibidis GD, Akhmanova A, Knoch TA, Grosveld F, Galjart N. Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends. J Cell Biol. 2008 Feb 25; 180(4):729-37. PMID: 18283108; PMCID: PMC2265578.
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