Jeremy Horst, DDS, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentBiochemistry and Biophysics
Address1700 4th St
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    UC San FranciscoPostdocnowBiochemistry / Infectious Disease
    UC San FranciscoResidency2013Pediatric Dentistry
    Univ WashingtonPhD2010Oral Biology / Computational Biology
    Univ WashingtonDDS2008Dental
    UC San DiegoMS2004Chemistry
    UC San DiegoBS2003Pharmacological Chemistry
    UC San DiegoBA2003Psychology

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Horst J, Tanzer JM, Milgrom PM. Fluorides and Other Preventive Strategies for Tooth Decay. Dent Clin North Am. 2018 Apr; 62(2):207-234. PMID: 29478454.
      View in: PubMed
    2. Milgrom P, Horst J, Ludwig S, Rothen M, Chaffee BW, Lyalina S, Pollard KS, DeRisi JL, Mancl L. Topical silver diamine fluoride for dental caries arrest in preschool children: A randomized controlled trial and microbiological analysis of caries associated microbes and resistance gene expression. J Dent. 2018 Jan; 68:72-78. PMID: 28866468.
      View in: PubMed
    3. Milgrom PM, Horst J. The Effect of New Oral Care Technologies on the Need for Dentists in 2040. J Dent Educ. 2017 Aug; 81(8):eS126-eS132. PMID: 28765464.
      View in: PubMed
    4. Crawford ED, Quan J, Horst J, Ebert D, Wu W, DeRisi JL. Plasmid-free CRISPR/Cas9 genome editing in Plasmodium falciparum confirms mutations conferring resistance to the dihydroisoquinolone clinical candidate SJ733. PLoS One. 2017; 12(5):e0178163. PMID: 28542423.
      View in: PubMed
    5. Horst J, Wu W, DeRisi JL. MinorityReport, software for generalized analysis of causal genetic variants. Malar J. 2017 02 23; 16(1):90. PMID: 28231785.
      View in: PubMed
    6. Horst J, Frachella JC, Duffin S. Response to Letter to the Editor. Pediatr Dent. 2016 11 15; 38(7):462-463. PMID: 28281948.
      View in: PubMed
    7. Bruce AG, Horst J, Rose TM. Conservation of the glycoprotein B homologs of the Kaposi?s sarcoma-associated herpesvirus (KSHV/HHV8) and old world primate rhadinoviruses of chimpanzees and macaques. Virology. 2016 07; 494:29-46. PMID: 27070755; PMCID: PMC4884460 [Available on 07/01/17].
    8. Carneiro KM, Zhai H, Zhu L, Horst J, Sitlin M, Nguyen M, Wagner M, Simpliciano C, Milder M, Chen CL, Ashby P, Bonde J, Li W, Habelitz S. Amyloid-like ribbons of amelogenins in enamel mineralization. Sci Rep. 2016 Mar 24; 6:23105. PMID: 27009419; PMCID: PMC4806362.
    9. Horst J, Ellenikiotis H, Milgrom PL. UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent. J Calif Dent Assoc. 2016 Jan; 44(1):16-28. PMID: 26897901; PMCID: PMC4778976.
    10. Jiménez-Díaz MB, Ebert D, Salinas Y, Pradhan A, Lehane AM, Myrand-Lapierre ME, O'Loughlin KG, Shackleford DM, Justino de Almeida M, Carrillo AK, Clark JA, Dennis AS, Diep J, Deng X, Duffy S, Endsley AN, Fedewa G, Guiguemde WA, Gómez MG, Holbrook G, Horst J, Kim CC, Liu J, Lee MC, Matheny A, Martínez MS, Miller G, Rodríguez-Alejandre A, Sanz L, Sigal M, Spillman NJ, Stein PD, Wang Z, Zhu F, Waterson D, Knapp S, Shelat A, Avery VM, Fidock DA, Gamo FJ, Charman SA, Mirsalis JC, Ma H, Ferrer S, Kirk K, Angulo-Barturen I, Kyle DE, DeRisi JL, Floyd DM, Guy RK. (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium. Proc Natl Acad Sci U S A. 2014 Dec 16; 111(50):E5455-62. PMID: 25453091; PMCID: PMC4273362.
    11. Milgrom P, Taves DM, Kim AS, Watson GE, Horst J. Pharmacokinetics of fluoride in toddlers after application of 5% sodium fluoride dental varnish. Pediatrics. 2014 Sep; 134(3):e870-4. PMID: 25136045; PMCID: PMC4143996.
    12. Smith JD, Hing AV, Clarke CM, Johnson NM, Perez FA, Park SS, Horst J, Mecham B, Maves L, Nickerson DA. Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis. Am J Hum Genet. 2014 Aug 07; 95(2):235-40. PMID: 25105228; PMCID: PMC4129399.
    13. Katsura KA, Horst J, Chandra D, Le TQ, Nakano Y, Zhang Y, Horst OV, Zhu L, Le MH, DenBesten PK. WDR72 models of structure and function: a stage-specific regulator of enamel mineralization. Matrix Biol. 2014 Sep; 38:48-58. PMID: 25008349; PMCID: PMC4185229.
    14. Minie M, Chopra G, Sethi G, Horst J, White G, Roy A, Hatti K, Samudrala R. CANDO and the infinite drug discovery frontier. Drug Discov Today. 2014 Sep; 19(9):1353-63. PMID: 24980786; PMCID: PMC4167471.
    15. Martinez-Avila O, Wu S, Kim SJ, Cheng Y, Khan F, Samudrala R, Sali A, Horst J, Habelitz S. Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils. Biomacromolecules. 2012 Nov 12; 13(11):3494-502. PMID: 22974364; PMCID: PMC3496023.
    16. Horst J, Pieper U, Sali A, Zhan L, Chopra G, Samudrala R, Featherstone JD. Strategic protein target analysis for developing drugs to stop dental caries. Adv Dent Res. 2012 Sep; 24(2):86-93. PMID: 22899687; PMCID: PMC3420364.
    17. Gungormus M, Oren EE, Horst J, Fong H, Hnilova M, Somerman MJ, Snead ML, Samudrala R, Tamerler C, Sarikaya M. Cementomimetics-constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides. Int J Oral Sci. 2012 Jun; 4(2):69-77. PMID: 22743342; PMCID: PMC3412665.
    18. Rieder MJ, Green GE, Park SS, Stamper BD, Gordon CT, Johnson JM, Cunniff CM, Smith JD, Emery SB, Lyonnet S, Amiel J, Holder M, Heggie AA, Bamshad MJ, Nickerson DA, Cox TC, Hing AV, Horst J, Cunningham ML. A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome. Am J Hum Genet. 2012 May 04; 90(5):907-14. PMID: 22560091; PMCID: PMC3376493.
    19. Roberts MC, Soge OO, Horst J, Ly KA, Milgrom P. Methicillin-resistant Staphylococcus aureus from dental school clinic surfaces and students. Am J Infect Control. 2011 Oct; 39(8):628-32. PMID: 21962840.
      View in: PubMed
    20. Horst OV, Horst J, Samudrala R, Dale BA. Caries induced cytokine network in the odontoblast layer of human teeth. BMC Immunol. 2011 Jan 24; 12:9. PMID: 21261944.
      View in: PubMed
    21. Cunningham ML, Horst J, Rieder MJ, Hing AV, Stanaway IB, Park SS, Samudrala R, Speltz ML. IGF1R variants associated with isolated single suture craniosynostosis. Am J Med Genet A. 2011 Jan; 155A(1):91-7. PMID: 21204214; PMCID: PMC3059230.
    22. Horst J, Wang K, Horst OV, Cunningham ML, Samudrala R. Disease risk of missense mutations using structural inference from predicted function. Curr Protein Pept Sci. 2010 Nov; 11(7):573-88. PMID: 20887259.
      View in: PubMed
    23. Horst J, Samudrala R. A protein sequence meta-functional signature for calcium binding residue prediction. Pattern Recognit Lett. 2010 Oct 15; 31(14):2103-2112. PMID: 20824111.
      View in: PubMed
    24. Dibble CF, Horst J, Malone MH, Park K, Temple B, Cheeseman H, Barbaro JR, Johnson GL, Bencharit S. Defining the functional domain of programmed cell death 10 through its interactions with phosphatidylinositol-3,4,5-trisphosphate. PLoS One. 2010 Jul 23; 5(7):e11740. PMID: 20668527; PMCID: PMC2909203.
    25. Liu T, Horst J, Samudrala R. A novel method for predicting and using distance constraints of high accuracy for refining protein structure prediction. Proteins. 2009 Oct; 77(1):220-34. PMID: 19422061; PMCID: PMC2874729.
    26. Horst J, Samudrala R. Diversity of protein structures and difficulties in fold recognition: the curious case of protein G. F1000 Biol Rep. 2009 Sep 08; 1:69. PMID: 20209018.
      View in: PubMed
    27. Horst J, Clark MD, Lee AH. Observation, assisting, apprenticeship: cycles of visual and kinesthetic learning in dental education. J Dent Educ. 2009 Aug; 73(8):919-33. PMID: 19648563; PMCID: PMC2759978.
    28. Wang K, Horst J, Cheng G, Nickle DC, Samudrala R. Protein meta-functional signatures from combining sequence, structure, evolution, and amino acid property information. PLoS Comput Biol. 2008 Sep 26; 4(9):e1000181. PMID: 18818722; PMCID: PMC2526173.
    29. Jenwitheesuk E, Horst J, Rivas KL, Van Voorhis WC, Samudrala R. Novel paradigms for drug discovery: computational multitarget screening. Trends Pharmacol Sci. 2008 Feb; 29(2):62-71. PMID: 18190973; PMCID: PMC4551513.
    30. Horst J. Bootstrapping student publication in the JDE: an ADEA council of students initiative. J Dent Educ. 2007 Oct; 71(10):1265-6. PMID: 17923704.
      View in: PubMed
    31. Oganesian A, Au S, Horst J, Holzhausen LC, Macy AJ, Pace JM, Bornstein P. The NH2-terminal propeptide of type I procollagen acts intracellularly to modulate cell function. J Biol Chem. 2006 Dec 15; 281(50):38507-18. PMID: 17018525; PMCID: PMC3086210.
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