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Jillian Silva, PhD

Title(s)Assistant Researcher, HDF Comprehensive Cancer Ctr
SchoolSchool of Medicine
Phone415-502-1868
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms of cooperation between MAPK and PI3K signaling in melanoma
    NIH/NCI K01CA197138Jul 6, 2015 - Jun 30, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Silva JM, Deuker MM, Baguley BC, McMahon M. PIK3CA-mutated melanoma cells rely on cooperative signaling through mTORC1/2 for sustained proliferation. Pigment Cell Melanoma Res. 2017 05; 30(3):353-367. PMID: 28233937.
      View in: PubMed
    2. Charles RP, Silva J, Iezza G, Phillips WA, McMahon M. Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid carcinogenesis. Mol Cancer Res. 2014 Jul; 12(7):979-86. PMID: 24770869; PMCID: PMC4635659.
      View in: PubMed, PubMed Central
    3. Silva JM, McMahon M. The fastest Western in town: a contemporary twist on the classic Western blot analysis. J Vis Exp. 2014 Feb 05; (84):e51149. PMID: 24561642; PMCID: PMC4028330.
      View in: PubMed, PubMed Central
    4. Silva JM, Bulman C, McMahon M. BRAFV600E cooperates with PI3K signaling, independent of AKT, to regulate melanoma cell proliferation. Mol Cancer Res. 2014 Mar; 12(3):447-63. PMID: 24425783; PMCID: PMC3966216.
      View in: PubMed, PubMed Central
    5. Collisson EA, Trejo CL, Silva JM, Gu S, Korkola JE, Heiser LM, Charles RP, Rabinovich BA, Hann B, Dankort D, Spellman PT, Phillips WA, Gray JW, McMahon M. A central role for RAF?MEK?ERK signaling in the genesis of pancreatic ductal adenocarcinoma. Cancer Discov. 2012 Aug; 2(8):685-93. PMID: 22628411; PMCID: PMC3425446.
      View in: PubMed, PubMed Central
    6. Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivée B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A. Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J Cell Biol. 2010 Jan 11; 188(1):115-30. PMID: 20065093; PMCID: PMC2812843.
      View in: PubMed, PubMed Central
    7. Schoenfeld R, Wong A, Silva J, Li M, Itoh A, Horiuchi M, Itoh T, Pleasure D, Cortopassi G. Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation. Mitochondrion. 2010 Mar; 10(2):143-50. PMID: 20005986; PMCID: PMC3119038.
      View in: PubMed, PubMed Central
    8. Silva JM, Wong A, Carelli V, Cortopassi GA. Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia. Neurobiol Dis. 2009 May; 34(2):357-65. PMID: 19233273.
      View in: PubMed
    9. Sevigny MB, Silva JM, Lan WC, Alano CC, Swanson RA. Expression and activity of poly(ADP-ribose) glycohydrolase in cultured astrocytes, neurons, and C6 glioma cells. Brain Res Mol Brain Res. 2003 Oct 07; 117(2):213-20. PMID: 14559156.
      View in: PubMed
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