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Jimmy Hu, PhD

TitleAssistant Researcher
SchoolUCSF School of Dentistry
DepartmentOrofacial Sciences
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-476-4720
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    Collapse Research 
    Collapse Research Activities and Funding
    An investigation of the roles of mechanical signaling in YAP-mediated tooth renewal
    NIH/NIDCR K99DE025874Jul 1, 2016 - Jun 30, 2018
    Role: Principal Investigator
    The role of YAP/TAZ and Hippo signaling in mouse incisor stem cells
    NIH/NIDCR F32DE023705Jul 1, 2013 - Jun 30, 2016
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Du W, Hu J, Du W, Klein OD. Lineage tracing of epithelial cells in developing teeth reveals two strategies for building signaling centers. J Biol Chem. 2017 Sep 08; 292(36):15062-15069. PMID: 28733464.
      View in: PubMed
    2. Hu J, Du W, Shelton SJ, Oldham MC, DiPersio CM, Klein OD. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice. Cell Stem Cell. 2017 Jul 06; 21(1):91-106.e6. PMID: 28457749.
      View in: PubMed
    3. Tschopp P, Sherratt E, Sanger TJ, Groner AC, Aspiras AC, Hu J, Pourquié O, Gros J, Tabin CJ. A relative shift in cloacal location repositions external genitalia in amniote evolution. Nature. 2014 Dec 18; 516(7531):391-4. PMID: 25383527; PMCID: PMC4294627.
    4. Chavez MG, Hu J, Seidel K, Li C, Jheon A, Naveau A, Horst O, Klein OD. Isolation and culture of dental epithelial stem cells from the adult mouse incisor. J Vis Exp. 2014 May 01; (87). PMID: 24834972; PMCID: PMC4141628.
    5. Kuang-Hsien Hu J, Mushegyan V, Klein OD. On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. Genesis. 2014 Feb; 52(2):79-92. PMID: 24307456; PMCID: PMC4252016.
    6. Biehs B, Hu J, Strauli NB, Sangiorgi E, Jung H, Heber RP, Ho S, Goodwin AF, Dasen JS, Capecchi MR, Klein OD. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol. 2013 Jul; 15(7):846-52. PMID: 23728424; PMCID: PMC3735916.
    7. Hu J, McGlinn E, Harfe BD, Kardon G, Tabin CJ. Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation. Genes Dev. 2012 Sep 15; 26(18):2088-102. PMID: 22987639; PMCID: PMC3444734.
    8. Cooper KL, Hu J, ten Berge D, Fernandez-Teran M, Ros MA, Tabin CJ. Initiation of proximal-distal patterning in the vertebrate limb by signals and growth. Science. 2011 May 27; 332(6033):1083-6. PMID: 21617075; PMCID: PMC3258580.
    9. Gros J, Hu J, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ. WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud. Curr Biol. 2010 Nov 23; 20(22):1993-2002. PMID: 21055947; PMCID: PMC2998074.
    10. Schlabach MR, Hu J, Li M, Elledge SJ. Synthetic design of strong promoters. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2538-43. PMID: 20133776; PMCID: PMC2823900.
    11. Purcell P, Joo BW, Hu J, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ. Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43):18297-302. PMID: 19815519; PMCID: PMC2775291.
    12. Loscertales M, Mikels AJ, Hu J, Donahoe PK, Roberts DJ. Chick pulmonary Wnt5a directs airway and vascular tubulogenesis. Development. 2008 Apr; 135(7):1365-76. PMID: 18305003.
      View in: PubMed
    13. Horsfield JA, Anagnostou SH, Hu J, Cho KH, Geisler R, Lieschke G, Crosier KE, Crosier PS. Cohesin-dependent regulation of Runx genes. Development. 2007 Jul; 134(14):2639-49. PMID: 17567667.
      View in: PubMed
    14. Hornstein E, Mansfield JH, Yekta S, Hu J, Harfe BD, McManus MT, Baskerville S, Bartel DP, Tabin CJ. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature. 2005 Dec 01; 438(7068):671-4. PMID: 16319892.
      View in: PubMed
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