Jin Chen, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentCellular Molecular Pharmacology
Address1700 4th St
San Francisco CA 94158
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    Stanford UniversityPh.D.2015Applied Physics

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chen J, Choi J, O'Leary SE, Prabhakar A, Petrov A, Grosely R, Puglisi EV, Puglisi JD. The molecular choreography of protein synthesis: translational control, regulation, and pathways. Q Rev Biophys. 2016 Jan; 49:e11. PMID: 27658712.
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    2. Navon SP, Kornberg G, Chen J, Schwartzman T, Tsai A, Puglisi EV, Puglisi JD, Adir N. Amino acid sequence repertoire of the bacterial proteome and the occurrence of untranslatable sequences. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7166-70. PMID: 27307442; PMCID: PMC4932979 [Available on 12/28/16].
    3. Petrov A, Grosely R, Chen J, O'Leary SE, Puglisi JD. Multiple Parallel Pathways of Translation Initiation on the CrPV IRES. Mol Cell. 2016 Apr 07; 62(1):92-103. PMID: 27058789; PMCID: PMC4826567 [Available on 04/07/17].
    4. Choi J, Ieong KW, Demirci H, Chen J, Petrov A, Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis SM, Ehrenberg M, Puglisi JD. N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat Struct Mol Biol. 2016 Feb; 23(2):110-5. PMID: 26751643; PMCID: PMC4826618.
    5. Chen J, Coakley A, O'Connor M, Petrov A, O'Leary SE, Atkins JF, Puglisi JD. Coupling of mRNA Structure Rearrangement to Ribosome Movement during Bypassing of Non-coding Regions. Cell. 2015 Nov 19; 163(5):1267-1280. PMID: 26590426; PMCID: PMC4813330 [Available on 11/19/16].
    6. Fuchs G, Petrov AN, Marceau CD, Popov LM, Chen J, O'Leary SE, Wang R, Carette JE, Sarnow P, Puglisi JD. Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):319-25. PMID: 25516984; PMCID: PMC4299178.
    7. Noriega TR, Chen J, Walter P, Puglisi JD. Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife. 2014 Oct 30; 3. PMID: 25358118; PMCID: PMC4213662.
    8. Chen J, Petrov A, Johansson M, Tsai A, O'Leary SE, Puglisi JD. Dynamic pathways of -1 translational frameshifting. Nature. 2014 Aug 21; 512(7514):328-32. PMID: 24919156; PMCID: PMC4472451.
    9. Johansson M, Chen J, Tsai A, Kornberg G, Puglisi JD. Sequence-dependent elongation dynamics on macrolide-bound ribosomes. Cell Rep. 2014 Jun 12; 7(5):1534-1546. PMID: 24836000; PMCID: PMC4387896.
    10. Tsai A, Kornberg G, Johansson M, Chen J, Puglisi JD. The dynamics of SecM-induced translational stalling. Cell Rep. 2014 Jun 12; 7(5):1521-1533. PMID: 24836001; PMCID: PMC4059775.
    11. Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem. 2014 Jul 11; 289(28):19294-305. PMID: 24808175; PMCID: PMC4094042.
    12. Chen J, Dalal RV, Petrov AN, Tsai A, O'Leary SE, Chapin K, Cheng J, Ewan M, Hsiung PL, Lundquist P, Turner SW, Hsu DR, Puglisi JD. High-throughput platform for real-time monitoring of biological processes by multicolor single-molecule fluorescence. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):664-9. PMID: 24379388; PMCID: PMC3896158.
    13. O'Leary SE, Petrov A, Chen J, Puglisi JD. Dynamic recognition of the mRNA cap by Saccharomyces cerevisiae eIF4E. Structure. 2013 Dec 03; 21(12):2197-207. PMID: 24183571; PMCID: PMC3878992.
    14. Chen J, Petrov A, Tsai A, O'Leary SE, Puglisi JD. Coordinated conformational and compositional dynamics drive ribosome translocation. Nat Struct Mol Biol. 2013 Jun; 20(6):718-27. PMID: 23624862; PMCID: PMC3883222.
    15. Chen J, Tsai A, O'Leary SE, Petrov A, Puglisi JD. Unraveling the dynamics of ribosome translocation. Curr Opin Struct Biol. 2012 Dec; 22(6):804-14. PMID: 23142574; PMCID: PMC3766728.
    16. Petrov A, Chen J, O'Leary S, Tsai A, Puglisi JD. Single-molecule analysis of translational dynamics. Cold Spring Harb Perspect Biol. 2012 Sep 01; 4(9):a011551. PMID: 22798542; PMCID: PMC3428772.
    17. Chen J, Tsai A, Petrov A, Puglisi JD. Nonfluorescent quenchers to correlate single-molecule conformational and compositional dynamics. J Am Chem Soc. 2012 Apr 04; 134(13):5734-7. PMID: 22428667; PMCID: PMC4369913.
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