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Jin Chen, PhD

Title(s)Postdoctoral Scholar, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Phone415-502-8089
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityPh.D.2015Applied Physics

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chen J, Choi J, O'Leary SE, Prabhakar A, Petrov A, Grosely R, Puglisi EV, Puglisi JD. The molecular choreography of protein synthesis: translational control, regulation, and pathways. Q Rev Biophys. 2016 Jan; 49:e11. PMID: 27658712.
      View in: PubMed
    2. Navon SP, Kornberg G, Chen J, Schwartzman T, Tsai A, Puglisi EV, Puglisi JD, Adir N. Amino acid sequence repertoire of the bacterial proteome and the occurrence of untranslatable sequences. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):7166-70. PMID: 27307442.
      View in: PubMed
    3. Petrov A, Grosely R, Chen J, O'Leary SE, Puglisi JD. Multiple Parallel Pathways of Translation Initiation on the CrPV IRES. Mol Cell. 2016 Apr 07; 62(1):92-103. PMID: 27058789.
      View in: PubMed
    4. Choi J, Ieong KW, Demirci H, Chen J, Petrov A, Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis SM, Ehrenberg M, Puglisi JD. N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat Struct Mol Biol. 2016 Feb; 23(2):110-5. PMID: 26751643.
      View in: PubMed
    5. Chen J, Coakley A, O'Connor M, Petrov A, O'Leary SE, Atkins JF, Puglisi JD. Coupling of mRNA Structure Rearrangement to Ribosome Movement during Bypassing of Non-coding Regions. Cell. 2015 Nov 19; 163(5):1267-1280. PMID: 26590426.
      View in: PubMed
    6. Fuchs G, Petrov AN, Marceau CD, Popov LM, Chen J, O'Leary SE, Wang R, Carette JE, Sarnow P, Puglisi JD. Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):319-25. PMID: 25516984.
      View in: PubMed
    7. Noriega TR, Chen J, Walter P, Puglisi JD. Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife. 2014 Oct 30; 3. PMID: 25358118.
      View in: PubMed
    8. Chen J, Petrov A, Johansson M, Tsai A, O'Leary SE, Puglisi JD. Dynamic pathways of -1 translational frameshifting. Nature. 2014 Aug 21; 512(7514):328-32. PMID: 24919156.
      View in: PubMed
    9. Tsai A, Kornberg G, Johansson M, Chen J, Puglisi JD. The dynamics of SecM-induced translational stalling. Cell Rep. 2014 Jun 12; 7(5):1521-1533. PMID: 24836001.
      View in: PubMed
    10. Johansson M, Chen J, Tsai A, Kornberg G, Puglisi JD. Sequence-dependent elongation dynamics on macrolide-bound ribosomes. Cell Rep. 2014 Jun 12; 7(5):1534-1546. PMID: 24836000.
      View in: PubMed
    11. Noriega TR, Tsai A, Elvekrog MM, Petrov A, Neher SB, Chen J, Bradshaw N, Puglisi JD, Walter P. Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem. 2014 Jul 11; 289(28):19294-305. PMID: 24808175.
      View in: PubMed
    12. Chen J, Dalal RV, Petrov AN, Tsai A, O'Leary SE, Chapin K, Cheng J, Ewan M, Hsiung PL, Lundquist P, Turner SW, Hsu DR, Puglisi JD. High-throughput platform for real-time monitoring of biological processes by multicolor single-molecule fluorescence. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):664-9. PMID: 24379388.
      View in: PubMed
    13. O'Leary SE, Petrov A, Chen J, Puglisi JD. Dynamic recognition of the mRNA cap by Saccharomyces cerevisiae eIF4E. Structure. 2013 Dec 03; 21(12):2197-207. PMID: 24183571.
      View in: PubMed
    14. Chen J, Petrov A, Tsai A, O'Leary SE, Puglisi JD. Coordinated conformational and compositional dynamics drive ribosome translocation. Nat Struct Mol Biol. 2013 Jun; 20(6):718-27. PMID: 23624862.
      View in: PubMed
    15. Chen J, Tsai A, O'Leary SE, Petrov A, Puglisi JD. Unraveling the dynamics of ribosome translocation. Curr Opin Struct Biol. 2012 Dec; 22(6):804-14. PMID: 23142574.
      View in: PubMed
    16. Petrov A, Chen J, O'Leary S, Tsai A, Puglisi JD. Single-molecule analysis of translational dynamics. Cold Spring Harb Perspect Biol. 2012 Sep 01; 4(9):a011551. PMID: 22798542.
      View in: PubMed
    17. Chen J, Tsai A, Petrov A, Puglisi JD. Nonfluorescent quenchers to correlate single-molecule conformational and compositional dynamics. J Am Chem Soc. 2012 Apr 04; 134(13):5734-7. PMID: 22428667.
      View in: PubMed