Joao Braz, PhD

Title(s)ASSOC RES-FY, Anatomy
SchoolSchool of Medicine
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-4311
vCardDownload vCard

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Spinal Cord Transplants of GABAergic Precursor Cells to Treat Chronic Pain
    NIH R01NS078326Sep 28, 2012 - Jun 30, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Structure-based discovery of nonopioid analgesics acting through the a2A-adrenergic receptor. Science. 2022 09 30; 377(6614):eabn7065. Fink EA, Xu J, H?bner H, Braz JM, Seemann P, Avet C, Craik V, Weikert D, Schmidt MF, Webb CM, Tolmachova NA, Moroz YS, Huang XP, Kalyanaraman C, Gahbauer S, Chen G, Liu Z, Jacobson MP, Irwin JJ, Bouvier M, Du Y, Shoichet BK, Basbaum AI, Gmeiner P. PMID: 36173843.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    2. TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons. Elife. 2022 08 15; 11. Yue WWS, Yuan L, Braz JM, Basbaum AI, Julius D. PMID: 35968676; PMCID: PMC9377796.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Intraspinal Transplantation of Precursors of Cortical GABAergic Interneurons to Treat Neuropathic Pain. . 2022 May 27; 178:159-170. Braz BJ, Basbaum BA. .
      View in: Publisher Site   Mentions:
    4. ACVR1-activating mutation causes neuropathic pain and sensory neuron hyperexcitability in humans. Pain. 2023 01 01; 164(1):43-58. Yu X, Ton AN, Niu Z, Morales BM, Chen J, Braz J, Lai MH, Barruet E, Liu H, Cheung K, Ali S, Chan T, Bigay K, Ho J, Nikolli I, Hansberry S, Wentworth K, Kriegstein A, Basbaum A, Hsiao EC. PMID: 35442931; PMCID: PMC9582048.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022 03 10; 65(5):4201-4217. Levit Kaplan A, Strachan RT, Braz JM, Craik V, Slocum S, Mangano T, Amabo V, O'Donnell H, Lak P, Basbaum AI, Roth BL, Shoichet BK. PMID: 35195401; PMCID: PMC9116900.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Structures of the s2 receptor enable docking for bioactive ligand discovery. Nature. 2021 Dec; 600(7890):759-764. Alon A, Lyu J, Braz JM, Tummino TA, Craik V, O'Meara MJ, Webb CM, Radchenko DS, Moroz YS, Huang XP, Liu Y, Roth BL, Irwin JJ, Basbaum AI, Shoichet BK, Kruse AC. PMID: 34880501; PMCID: PMC8867396.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    7. Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice. Elife. 2021 10 15; 10. Kuhn JA, Vainchtein ID, Braz J, Hamel K, Bernstein M, Craik V, Dahlgren MW, Ortiz-Carpena J, Molofsky AB, Molofsky AV, Basbaum AI. PMID: 34652270; PMCID: PMC8639143.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    8. LB722 IL-31/IL31RA negatively regulate IL-4 production and cutaneous M2-like macrophage accumulation. Journal of Investigative Dermatology. 2021 Sep 1; 141(9):b5. Fassett FM, Braz BJ, Castellanos CC, Schroeder SA, Sadeghi SM, Mar MD, Zhou ZC, Shin SJ, Basbaum BA, Ansel AK. .
      View in: Publisher Site   Mentions:
    9. Pain and itch processing by subpopulations of molecularly diverse spinal and trigeminal projection neurons. Proc Natl Acad Sci U S A. 2021 07 13; 118(28). Wercberger R, Braz JM, Weinrich JA, Basbaum AI. PMID: 34234018; PMCID: PMC8285968.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    10. Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity. Elife. 2021 06 01; 10. L?ken LS, Braz JM, Etlin A, Sadeghi M, Bernstein M, Jewell M, Steyert M, Kuhn J, Hamel K, Llewellyn-Smith IJ, Basbaum A. PMID: 34061020; PMCID: PMC8245130.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    11. Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness. Proc Natl Acad Sci U S A. 2021 02 23; 118(8). Braz JM, Dembo T, Charruyer A, Ghadially R, Fassett MS, Basbaum AI. PMID: 33602818; PMCID: PMC7923356.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    12. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Nat Commun. 2020 01 14; 11(1):264. Yu X, Liu H, Hamel KA, Morvan MG, Yu S, Leff J, Guan Z, Braz JM, Basbaum AI. PMID: 31937758; PMCID: PMC6959328.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    13. Ablation of spinal cord estrogen receptor a-expressing interneurons reduces chemically induced modalities of pain and itch. J Comp Neurol. 2020 07; 528(10):1629-1643. Tran M, Braz JM, Hamel K, Kuhn J, Todd AJ, Basbaum AI. PMID: 31872868; PMCID: PMC7317200.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. GABAergic cell transplants in the anterior cingulate cortex reduce neuropathic pain aversiveness. Brain. 2019 09 01; 142(9):2655-2669. Juarez-Salinas DL, Braz JM, Etlin A, Gee S, Sohal V, Basbaum AI. PMID: 31321411; PMCID: PMC6752168.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    15. Microcircuit Mechanisms through which Mediodorsal Thalamic Input to Anterior Cingulate Cortex Exacerbates Pain-Related Aversion. Neuron. 2019 06 05; 102(5):944-959.e3. Meda KS, Patel T, Braz JM, Malik R, Turner ML, Seifikar H, Basbaum AI, Sohal VS. PMID: 31030955; PMCID: PMC6554049.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    16. Morphological and functional properties distinguish the substance P and gastrin-releasing peptide subsets of excitatory interneuron in the spinal cord dorsal horn. Pain. 2019 Feb; 160(2):442-462. Dickie AC, Bell AM, Iwagaki N, Polg?r E, Gutierrez-Mecinas M, Kelly R, Lyon H, Turnbull K, West SJ, Etlin A, Braz J, Watanabe M, Bennett DLH, Basbaum AI, Riddell JS, Todd AJ. PMID: 30247267; PMCID: PMC6330098.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    17. Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls. Pain Rep. 2018 Jul-Aug; 3(4):e659. Juarez-Salinas DL, Braz JM, Hamel KA, Basbaum AI. PMID: 30123855; PMCID: PMC6085145.
      View in: PubMed   Mentions: 8  
    18. NaV1.1 inhibition can reduce visceral hypersensitivity. JCI Insight. 2018 06 07; 3(11). Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, Bosmans F. PMID: 29875317; PMCID: PMC6124407.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    19. Synergistic antipruritic effects of gamma aminobutyric acid A�and B agonists in a mouse model of atopic dermatitis. J Allergy Clin Immunol. 2017 Aug; 140(2):454-464.e2. Cevikbas F, Braz JM, Wang X, Solorzano C, Sulk M, Buhl T, Steinhoff M, Basbaum AI. PMID: 28232084; PMCID: PMC5546982.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    20. Rebuilding CNS inhibitory circuits to control chronic neuropathic pain and itch. Prog Brain Res. 2017; 231:87-105. Braz JM, Etlin A, Juarez-Salinas D, Llewellyn-Smith IJ, Basbaum AI. PMID: 28554402.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    21. Peripheral and central neuronal ATF3 precedes CD4+ T-cell infiltration in EAE. Exp Neurol. 2016 09; 283(Pt A):224-34. Frezel N, Sohet F, Daneman R, Basbaum AI, Braz JM. PMID: 27343802; PMCID: PMC5500277.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    22. Injured sensory neuron-derived CSF1 induces microglial proliferation and DAP12-dependent pain. Nat Neurosci. 2016 Jan; 19(1):94-101. Guan Z, Kuhn JA, Wang X, Colquitt B, Solorzano C, Vaman S, Guan AK, Evans-Reinsch Z, Braz J, Devor M, Abboud-Werner SL, Lanier LL, Lomvardas S, Basbaum AI. PMID: 26642091; PMCID: PMC4703328.
      View in: PubMed   Mentions: 200     Fields:    Translation:AnimalsCells
    23. Dorsal Horn Parvalbumin Neurons Are Gate-Keepers of Touch-Evoked Pain after Nerve Injury. Cell Rep. 2015 Nov 10; 13(6):1246-1257. Petitjean H, Pawlowski SA, Fraine SL, Sharif B, Hamad D, Fatima T, Berg J, Brown CM, Jan LY, Ribeiro-da-Silva A, Braz JM, Basbaum AI, Sharif-Naeini R. PMID: 26527000; PMCID: PMC6038918.
      View in: PubMed   Mentions: 134     Fields:    Translation:AnimalsCells
    24. CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine. Sci Transl Med. 2015 Sep 16; 7(305):305ra145. Brown JD, Saeed M, Do L, Braz J, Basbaum AI, Iadarola MJ, Wilson DM, Dillon WP. PMID: 26378245; PMCID: PMC4854290.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    25. Transplant restoration of spinal cord inhibitory controls ameliorates neuropathic itch. J Clin Invest. 2014 Aug; 124(8):3612-6. Braz JM, Juarez-Salinas D, Ross SE, Basbaum AI. PMID: 25003193; PMCID: PMC4109547.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    26. Transmitting Pain and Itch Messages: A Contemporary View of the Spinal Cord Circuits that Generate Gate Control. Neuron. 2014 Jun 1; 82(6):1407. Braz BJ, Solorzano SC, Wang WX, Basbaum BA. .
      View in: Publisher Site   Mentions:
    27. Sciatic nerve transection triggers release and intercellular transfer of a genetically expressed macromolecular tracer in dorsal root ganglia. J Comp Neurol. 2011 Sep 01; 519(13):2648-57. Br?z JM, Ackerman L, Basbaum AI. PMID: 21484801; PMCID: PMC3864657.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci. 2011 Jul 13; 31(28):10119-27. Cavanaugh DJ, Chesler AT, Br?z JM, Shah NM, Julius D, Basbaum AI. PMID: 21752988; PMCID: PMC3147010.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    29. Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli. Pain. 2010 Aug; 150(2):290-301. Br?z JM, Basbaum AI. PMID: 20605331; PMCID: PMC2922479.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    30. 320 DIFFERENTIAL ATF3 EXPRESSION REVEALS THE PROFILE OF DORSAL ROOT GANGLION (DRG) NEURONS ACTIVATED BY DIVERSE NOXIOUS CHEMICAL STIMULI. European Journal of Pain. 2009 Sep 1; 13(S1):s98a-s98. Braz BJ, Basbaum BA. .
      View in: Publisher Site   Mentions:
    31. Triggering genetically-expressed transneuronal tracers by peripheral axotomy reveals convergent and segregated sensory neuron-spinal cord connectivity. Neuroscience. 2009 Nov 10; 163(4):1220-32. Bráz JM, Basbaum AI. PMID: 19647044; PMCID: PMC2760676.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    32. Inputs to serotonergic neurons revealed by conditional viral transneuronal tracing. J Comp Neurol. 2009 May 10; 514(2):145-60. Braz JM, Enquist LW, Basbaum AI. PMID: 19274668; PMCID: PMC2696271.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    33. Chapter 22 The Endogenous Neuromodulation System. Neuromodulation. 2009 Jan 1; 303-312. Basbaum BA, Braz BJ, Ossipov OM, Porreca PF. .
      View in: Publisher Site   Mentions:
    34. Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers. J Neurosci. 2008 Aug 06; 28(32):7936-44. Neumann S, Braz JM, Skinner K, Llewellyn-Smith IJ, Basbaum AI. PMID: 18685019; PMCID: PMC3844752.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    35. Genetically expressed transneuronal tracer reveals direct and indirect serotonergic descending control circuits. J Comp Neurol. 2008 Apr 20; 507(6):1990-2003. Braz JM, Basbaum AI. PMID: 18273889; PMCID: PMC4947410.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    36. Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor. Neuron. 2005 Sep 15; 47(6):787-93. Braz JM, Nassar MA, Wood JN, Basbaum AI. PMID: 16157274.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    37. [From inflammation to pain: experimental gene therapy]. Med Sci (Paris). 2004 Mar; 20(3):325-30. Meunier A, Braz J, Cesselin F, Hamon M, Pohl M. PMID: 15067578.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    38. Gene therapy of chronic pain. Curr Gene Ther. 2003 Jun; 3(3):223-38. Pohl M, Meunier A, Hamon M, Braz J. PMID: 12762481.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    39. Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):15148-53. Braz JM, Rico B, Basbaum AI. PMID: 12391304; PMCID: PMC137558.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    40. The neuropeptide FF analogue, 1DMe, reduces in vivo dynorphin release from the rat spinal cord. J Neurochem. 2002 May; 81(3):659-62. Ballet S, Braz J, Mauborgne A, Bourgoin S, Zajac JM, Hamon M, Cesselin F. PMID: 12065675.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    41. Gene therapy of pain: emerging strategies and future directions. Eur J Pharmacol. 2001 Oct 19; 429(1-3):39-48. Pohl M, Braz J. PMID: 11698025.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    42. Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons. J Neurosci. 2001 Oct 15; 21(20):7881-8. Braz J, Beaufour C, Coutaux A, Epstein AL, Cesselin F, Hamon M, Pohl M. PMID: 11588161; PMCID: PMC6763863.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    43. Effets analgésiques des morphiniques et systèmes opioïdergiques dans les douleurs chroniques: confrontation des données cliniques et des données expérimentales chez l’animal. Douleur et Analgésie. 2001 Mar 1; 14(1):49-58. Braz BJ, Coutaux CA. .
      View in: Publisher Site   Mentions:
    44. Met-enkephalin is preferentially transported into the peripheral processes of primary afferent fibres in both control and HSV1-driven proenkephalin A overexpressing rats. Neuroscience. 2001; 103(4):1073-83. Antunes bras J, Becker C, Bourgoin S, Lombard M, Cesselin F, Hamon M, Pohl M. PMID: 11301214.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    45. Effects of peripheral axotomy on cholecystokinin neurotransmission in the rat spinal cord. J Neurochem. 1999 Feb; 72(2):858-67. Antunes Bras JM, Laporte AM, Benoliel JJ, Bourgoin S, Mauborgne A, Hamon M, Cesselin F, Pohl M. PMID: 9930763.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. Herpes simplex virus 1-mediated transfer of preproenkephalin A in rat dorsal root ganglia. J Neurochem. 1998 Mar; 70(3):1299-303. Antunes Bras JM, Epstein AL, Bourgoin S, Hamon M, Cesselin F, Pohl M. PMID: 9489753.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    Joao's Networks
    Concepts (261)
    Derived automatically from this person's publications.
    _
    Co-Authors (26)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _