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NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting. Nat Immunol. 2020 10; 21(10):1267-1279.
Tan C, Hiwa R, Mueller JL, Vykunta V, Hibiya K, Noviski M, Huizar J, Brooks JF, Garcia J, Heyn C, Li Z, Marson A, Zikherman J. PMID: 32868928.
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AnimalsCells
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Self-reactivity on a spectrum: A sliding scale of peripheral B cell tolerance. Immunol Rev. 2019 11; 292(1):37-60.
Tan C, Noviski M, Huizar J, Zikherman J. PMID: 31631352.
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5 Fields:
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HumansAnimalsCells
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Optimal Development of Mature B Cells Requires Recognition of Endogenous Antigens. J Immunol. 2019 07 15; 203(2):418-428.
Noviski M, Tan C, Huizar J, Vykunta V, Mueller JL, Zikherman J. PMID: 31167773.
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5 Fields:
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AnimalsCells
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Nur77 Links Chronic Antigen Stimulation to B Cell Tolerance by Restricting the Survival of Self-Reactive B Cells in the Periphery. J Immunol. 2019 05 15; 202(10):2907-2923.
Tan C, Mueller JL, Noviski M, Huizar J, Lau D, Dubinin A, Molofsky A, Wilson PC, Zikherman J. PMID: 30962292.
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6 Fields:
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AnimalsCells
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Nur77 Is Upregulated in B-1a Cells by Chronic Self-Antigen Stimulation and Limits Generation of Natural IgM Plasma Cells. Immunohorizons. 2017 Nov 01; 1(9):188-197.
Huizar J, Tan C, Noviski M, Mueller JL, Zikherman J. PMID: 29152611.
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Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells. Cell Rep. 2017 05 23; 19(8):1558-1571.
Myers DR, Lau T, Markegard E, Lim HW, Kasler H, Zhu M, Barczak A, Huizar JP, Zikherman J, Erle DJ, Zhang W, Verdin E, Roose JP. PMID: 28538176.
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9 Fields:
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HumansAnimalsCells
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Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis. PLoS One. 2014; 9(12):e116249.
Prigozhin DM, Krieger IV, Huizar JP, Mavrici D, Waldo GS, Hung LW, Sacchettini JC, Terwilliger TC, Alber T. PMID: 25551456.
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Structural and biochemical analyses of Mycobacterium tuberculosis N-acetylmuramyl-L-alanine amidase Rv3717 point to a role in peptidoglycan fragment recycling. J Biol Chem. 2013 Nov 01; 288(44):31549-55.
Prigozhin DM, Mavrici D, Huizar JP, Vansell HJ, Alber T. PMID: 24019530.
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15 Fields:
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Cells
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tRNA binding, structure, and localization of the human interferon-induced protein IFIT5. Mol Cell. 2013 Feb 21; 49(4):743-50.
Katibah GE, Lee HJ, Huizar JP, Vogan JM, Alber T, Collins K. PMID: 23317505.
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32 Fields:
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HumansAnimalsCells