John Leech, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
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    1. Lacey KA, Leech J, Lalor SJ, McCormack N, Geoghegan JA, McLoughlin RM. The Staphylococcus aureus Cell Wall-Anchored Protein Clumping Factor A Is an Important T Cell Antigen. Infect Immun. 2017 12; 85(12). PMID: 28947645.
      View in: PubMed
    2. Leech J, Lacey KA, Mulcahy ME, Medina E, McLoughlin RM. IL-10 Plays Opposing Roles during Staphylococcus aureus Systemic and Localized Infections. J Immunol. 2017 03 15; 198(6):2352-2365. PMID: 28167629.
      View in: PubMed
    3. Mulcahy ME, Leech J, Renauld JC, Mills KH, McLoughlin RM. Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa. Mucosal Immunol. 2016 11; 9(6):1429-1441. PMID: 27007677.
      View in: PubMed
    4. Brown AF, Murphy AG, Lalor SJ, Leech J, O'Keeffe KM, Mac Aogáin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM. Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection. PLoS Pathog. 2015; 11(11):e1005226. PMID: 26539822; PMCID: PMC4634925.
    5. O'Keeffe KM, Wilk MM, Leech J, Murphy AG, Laabei M, Monk IR, Massey RC, Lindsay JA, Foster TJ, Geoghegan JA, McLoughlin RM. Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection. Infect Immun. 2015 Sep; 83(9):3445-57. PMID: 26099586; PMCID: PMC4534639.
    6. Sharif-Paghaleh E, Leech J, Sunassee K, Ali N, Sagoo P, Lechler RI, Smyth LA, Lombardi G, Mullen GE. Monitoring the efficacy of dendritic cell vaccination by early detection of (99m) Tc-HMPAO-labelled CD4(+) T cells. Eur J Immunol. 2014 Jul; 44(7):2188-91. PMID: 24643793; PMCID: PMC4211358.
    7. Brown AF, Leech J, Rogers TR, McLoughlin RM. Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design. Front Immunol. 2014 Jan 08; 4:507. PMID: 24409186; PMCID: PMC3884195.
    8. Safinia N, Leech J, Hernandez-Fuentes M, Lechler R, Lombardi G. Promoting transplantation tolerance; adoptive regulatory T cell therapy. Clin Exp Immunol. 2013 May; 172(2):158-68. PMID: 23574313; PMCID: PMC3628319.
    9. Leech J, Sharif-Paghaleh E, Maher J, Livieratos L, Lechler RI, Mullen GE, Lombardi G, Smyth LA. Whole-body imaging of adoptively transferred T cells using magnetic resonance imaging, single photon emission computed tomography and positron emission tomography techniques, with a focus on regulatory T cells. Clin Exp Immunol. 2013 May; 172(2):169-77. PMID: 23574314; PMCID: PMC3628320.
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