John Lynch, PhD

Title(s)Specialist, Epidemiology & Biostatistics
SchoolSchool of Medicine
Address550 16th. Street, #2768
San Francisco CA 94158
Phone415-514-8092
ORCID ORCID Icon0000-0003-3624-2741 Additional info
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Assessing the association of epigenetic age acceleration with osteoarthritis in the Multicenter Osteoarthritis Study (MOST). Osteoarthritis Cartilage. 2024 Jan 17. Yau MS, Okoro PC, Haugen IK, Lynch JA, Nevitt MC, Lewis CE, Torner JC, Felson DT. PMID: 38242313.
      View in: PubMed   Mentions:    Fields:    
    2. Thigh muscle and fat volumes are associated with knee cartilage abnormalities and bone marrow edema-like lesions: data from the osteoarthritis initiative. Skeletal Radiol. 2024 Jan 11. Manatrakul R, Pirmoazen AM, Bharadwaj UU, Akkaya Z, Giesler PJ, Lynch JA, Nevitt MC, McCulloch CE, Joseph GB, Link TM. PMID: 38206355.
      View in: PubMed   Mentions:    Fields:    
    3. Association of Medial Meniscus Root Tears and Nonroot Tears With Worsening of Radiographic Knee Osteoarthritis. Orthop J Sports Med. 2023 Sep; 11(9):23259671231195894. Chambers CC, Lynch JA, Feeley BT, Nevitt MC. PMID: 37711506; PMCID: PMC10498710.
      View in: PubMed   Mentions: 1  
    4. Associations between weight change, knee subcutaneous fat and cartilage thickness in overweight and obese individuals: 4-Year data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2023 11; 31(11):1515-1523. Joseph GB, Takakusagi M, Arcilla G, Lynch JA, Pedoia V, Majumdar S, Lane NE, Nevitt MC, McCulloch CE, Link TM. PMID: 37574110; PMCID: PMC10848315.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Prevalence of intra-articular mineralization on knee computed tomography: the multicenter osteoarthritis study. Osteoarthritis Cartilage. 2023 08; 31(8):1111-1120. Jarraya M, Guermazi A, Liew JW, Tolstykh I, Lynch JA, Aliabadi P, Felson DT, Clancy M, Nevitt M, Lewis CE, Torner J, Neogi T. PMID: 37088266; PMCID: PMC10524737.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Do associations with hand OA vary by knee osteoarthritis phenotype? Cross-sectional data from the Multicenter Osteoarthritis Study. Osteoarthr Cartil Open. 2023 Mar; 5(1):100331. Yau MS, Jonsson H, Lynch JA, Lewis CE, Torner JC, Nevitt MC, Felson DT. PMID: 36605850; PMCID: PMC9807822.
      View in: PubMed   Mentions:
    7. Effects of Weight Change on Knee and Hip Radiographic Measurements and Pain Over Four Years: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2023 04; 75(4):860-868. Joseph GB, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Link TM. PMID: 35245415; PMCID: PMC9440955.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    8. Multiparametric 3-D analysis of bone and joint space width at the knee from weight bearing computed tomography. Osteoarthr Imaging. 2022 Jun; 2(2). Turmezei TD, Low SB, Rupret S, Treece GM, Gee AH, MacKay JW, Lynch JA, Poole KE, Segal NA. PMID: 36249485; PMCID: PMC9559750.
      View in: PubMed   Mentions: 1  
    9. Magnetic Resonance Imaging-Defined Osteoarthritis Features and Anterior Knee Pain in Individuals With, or at Risk for, Knee Osteoarthritis: A Multicenter Study on Osteoarthritis. Arthritis Care Res (Hoboken). 2022 09; 74(9):1533-1540. Macri EM, Neogi T, Jarraya M, Guermazi A, Roemer F, Lewis CE, Torner JC, Lynch JA, Tolstykh I, Jafarzadeh SR, Stefanik JJ. PMID: 33768706; PMCID: PMC8463633.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    10. Impact of Sustained Synovitis on Knee Joint Structural Degeneration: 4-Year MRI Data from the Osteoarthritis Initiative. J Magn Reson Imaging. 2023 01; 57(1):153-164. Ramezanpour S, Kanthawang T, Lynch J, McCulloch CE, Nevitt MC, Link TM, Joseph GB. PMID: 35561016; PMCID: PMC9653513.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    11. Multivariable Modeling of Biomarker Data From the Phase I Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium. Arthritis Care Res (Hoboken). 2022 07; 74(7):1142-1153. Hunter DJ, Deveza LA, Collins JE, Losina E, Katz JN, Nevitt MC, Lynch JA, Roemer FW, Guermazi A, Bowes MA, Dam EB, Eckstein F, Kwoh CK, Hoffmann S, Kraus VB. PMID: 33421361; PMCID: PMC8267050.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    12. Magnetic Resonance Imaging-Assessed Subchondral Cysts and Incident Knee Pain and Knee Osteoarthritis: Data From the Multicenter Osteoarthritis Study. Arthritis Rheumatol. 2022 01; 74(1):60-69. Perry TA, O'Neill TW, Tolstykh I, Lynch J, Felson DT, Arden NK, Nevitt MC. PMID: 34224660; PMCID: PMC9491692.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Longitudinal Relationship Between Tibiofemoral Contact Stress at Baseline and Worsening of Knee Pain Over 84 Months in the Multicenter Osteoarthritis Study. Am J Phys Med Rehabil. 2022 08 01; 101(8):726-732. Rabe KG, Stockman TJ, Kern AM, Wirth W, Eckstein F, Sharma L, Lynch JA, Nevitt MC, Anderson DD, Segal NA. PMID: 34620738; PMCID: PMC8986881.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Cross-sectional and longitudinal reliability of semiquantitative osteoarthritis assessment at 1.0T extremity MRI: Multi-reader data from the MOST study. Osteoarthr Cartil Open. 2021 Dec; 3(4):100214. Crema MD, Roemer FW, Nevitt MC, Felson DT, Marra MD, Lynch JA, Tolstykh I, Lewis CE, Torner J, Guermazi A. PMID: 36474762; PMCID: PMC9718190.
      View in: PubMed   Mentions:
    15. Clinical value of weight-bearing CT and radiographs for detecting patellofemoral cartilage visualized by MRI in the MOST study. Osteoarthritis Cartilage. 2021 11; 29(11):1540-1548. Segal NA, Murphy MT, Everist BM, Brown KD, He J, Lynch JA, Nevitt MC. PMID: 34332048; PMCID: PMC8542599.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI). Arthritis Res Ther. 2021 05 22; 23(1):146. Bodden J, Joseph GB, Schirò S, Lynch JA, Lane NE, McCulloch CE, Nevitt MC, Link TM. PMID: 34022942; PMCID: PMC8140460.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    17. Quantitative Three-dimensional Assessment of Knee Joint Space Width from Weight-bearing CT. Radiology. 2021 06; 299(3):649-659. Turmezei TD, B Low S, Rupret S, Treece GM, Gee AH, MacKay JW, Lynch JA, Poole KES, Segal NA. PMID: 33847516; PMCID: PMC9490554.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. Weight Cycling and Knee Joint Degeneration in Individuals with Overweight or Obesity: Four-Year Magnetic Resonance Imaging Data from the Osteoarthritis Initiative. Obesity (Silver Spring). 2021 05; 29(5):909-918. Joseph GB, Ramezanpour S, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Pedoia V, Majumdar S, Link TM. PMID: 33797183; PMCID: PMC9404626.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Bone Structure Analysis of the Radius Using Ultrahigh Field (7T) MRI: Relevance of Technical Parameters and Comparison with 3T MRI and Radiography. Diagnostics (Basel). 2021 Jan 12; 11(1). Jarraya M, Heiss R, Duryea J, Nagel AM, Lynch JA, Guermazi A, Weber MA, Arkudas A, Horch RE, Uder M, Roemer FW. PMID: 33445536; PMCID: PMC7826934.
      View in: PubMed   Mentions: 1  
    20. Predictive value of the morphology of proximal tibiofibular joint for total knee replacement in patients with knee osteoarthritis. J Orthop Res. 2021 06; 39(6):1289-1296. Zhao Y, Zhu Z, Chang J, Wang G, Zheng S, Kwoh CK, Lynch J, Hunter DJ, Ding C. PMID: 32940927.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Associations Between Vitamins C and D Intake and Cartilage Composition and Knee Joint Morphology Over 4 Years: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2020 09; 72(9):1239-1247. Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Lynch JA, Lane NE, Link TM. PMID: 31282125; PMCID: PMC6946891.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    22. Patterns of Change Over Time in Knee Bone Shape Are Associated with Sex. Clin Orthop Relat Res. 2020 07; 478(7):1491-1502. Wise BL, Niu J, Zhang Y, Liu F, Pang J, Lynch JA, Lane NE. PMID: 32187098; PMCID: PMC7310328.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Natural history of new horizontal meniscal tears in individuals at risk for and with mild to moderate osteoarthritis: data from osteoarthritis initiative. Eur Radiol. 2020 Nov; 30(11):5971-5980. Posadzy M, Joseph GB, McCulloch CE, Nevitt MC, Lynch JA, Lane NE, Link TM. PMID: 32572566.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Reliability of a new scoring system for intraarticular mineralization of the knee: Boston University Calcium Knee Score (BUCKS). Osteoarthritis Cartilage. 2020 06; 28(6):802-810. Guermazi A, Jarraya M, Lynch JA, Felson DT, Clancy M, Nevitt M, Lewis CE, Torner J, Neogi T. PMID: 32173626; PMCID: PMC8188576.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Varus alignment of the proximal tibia is associated with structural progression in early to moderate varus osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc. 2020 Oct; 28(10):3279-3286. Palmer JS, Jones LD, Monk AP, Nevitt M, Lynch J, Beard DJ, Javaid MK, Price AJ. PMID: 31965215; PMCID: PMC7511471.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    26. The Relationship of Three-Dimensional Joint Space Width on Weight Bearing CT With Pain and Physical Function. J Orthop Res. 2019 Dec 16. Kothari MD, Rabe KG, Anderson DD, Nevitt MC, Lynch JA, Segal NA, Franz H, Multicenter Osteoarthritis Study Group. PMID: 31840831; PMCID: PMC8016550.
      View in: PubMed   Mentions: 3     Fields:    
    27. A pilot study of peripheral blood DNA methylation models as predictors of knee osteoarthritis radiographic progression: data from the Osteoarthritis Initiative (OAI). Sci Rep. 2019 11 14; 9(1):16880. M Dunn C, Nevitt MC, Lynch JA, Jeffries MA. PMID: 31727952; PMCID: PMC6856188.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    28. The morphology of proximal tibiofibular joint (PTFJ) predicts incident radiographic osteoarthritis: data from Osteoarthritis Initiative. Osteoarthritis Cartilage. 2020 02; 28(2):208-214. Chang J, Zhu Z, Han W, Zhao Y, Kwoh CK, Lynch JA, Hunter DJ, Ding C. PMID: 31733306.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. MRI-based screening for structural definition of eligibility in clinical DMOAD trials: Rapid OsteoArthritis MRI Eligibility Score (ROAMES). Osteoarthritis Cartilage. 2020 01; 28(1):71-81. Roemer FW, Collins J, Kwoh CK, Hannon MJ, Neogi T, Felson DT, Hunter DJ, Lynch JA, Guermazi A. PMID: 31513920; PMCID: PMC7235947.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    30. Bone shape mediates the relationship between sex and incident knee osteoarthritis. BMC Musculoskelet Disord. 2018 Sep 12; 19(1):331. Wise BL, Niu J, Zhang Y, Liu F, Pang J, Lynch JA, Lane NE. PMID: 30208910; PMCID: PMC6136224.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    31. Signal intensity alteration within infrapatellar fat pad predicts knee replacement within 5 years: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018 10; 26(10):1345-1350. Wang K, Ding C, Hannon MJ, Chen Z, Kwoh CK, Lynch J, Hunter DJ. PMID: 29842941.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    32. Associations between molecular biomarkers and MR-based cartilage composition and knee joint morphology: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018 08; 26(8):1070-1077. Joseph GB, Nevitt MC, McCulloch CE, Neumann J, Lynch JA, Heilmeier U, Lane NE, Link TM. PMID: 29802973; PMCID: PMC6050081.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    33. Quantitative measurement of cartilage volume is possible using two-dimensional magnetic resonance imaging data sets. Osteoarthritis Cartilage. 2018 07; 26(7):920-923. Schaefer LF, Nikac V, Lynch JA, Duryea J. PMID: 29704559; PMCID: PMC6015652.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. Periarticular bone predicts knee osteoarthritis progression: Data from the Osteoarthritis Initiative. Semin Arthritis Rheum. 2018 10; 48(2):155-161. Lo GH, Schneider E, Driban JB, Price LL, Hunter DJ, Eaton CB, Hochberg MC, Jackson RD, Kwoh CK, Nevitt MC, Lynch JA, McAlindon TE, OAI Investigators Group. PMID: 29449014; PMCID: PMC6853601.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    35. Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 06; 47(6):1517-1526. Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link TM. PMID: 29143404; PMCID: PMC5955763.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    36. Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study. Osteoarthritis Cartilage. 2017 10; 25(10):1647-1653. Crema MD, Felson DT, Guermazi A, Nevitt MC, Niu J, Lynch JA, Marra MD, Torner J, Lewis CE, Roemer FW. PMID: 28606556; PMCID: PMC5605441.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. Relationship of Trochlear Morphology and Patellofemoral Joint Alignment to Superolateral Hoffa Fat Pad Edema on MR Images in Individuals with or at Risk for Osteoarthritis of the Knee: The MOST Study. Radiology. 2017 09; 284(3):806-814. Widjajahakim R, Roux M, Jarraya M, Roemer FW, Neogi T, Lynch JA, Lewis CE, Torner JC, Felson DT, Guermazi A, Stefanik JJ. PMID: 28418810; PMCID: PMC5584646.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    38. Quantitative measurement of medial femoral knee cartilage volume - analysis of the OA Biomarkers Consortium FNIH Study cohort. Osteoarthritis Cartilage. 2017 07; 25(7):1107-1113. Schaefer LF, Sury M, Yin M, Jamieson S, Donnell I, Smith SE, Lynch JA, Nevitt MC, Duryea J. PMID: 28153788; PMCID: PMC5466831.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    39. Semi-quantitative MRI biomarkers of knee osteoarthritis progression in the FNIH biomarkers consortium cohort - Methodologic aspects and definition of change. BMC Musculoskelet Disord. 2016 11 10; 17(1):466. Roemer FW, Guermazi A, Collins JE, Losina E, Nevitt MC, Lynch JA, Katz JN, Kwoh CK, Kraus VB, Hunter DJ. PMID: 27832771; PMCID: PMC5105263.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    40. Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Jun; 27(6):2497-2506. Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link TM. PMID: 27704199.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    41. Semiquantitative Imaging Biomarkers of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium. Arthritis Rheumatol. 2016 10; 68(10):2422-31. Collins JE, Losina E, Nevitt MC, Roemer FW, Guermazi A, Lynch JA, Katz JN, Kent Kwoh C, Kraus VB, Hunter DJ. PMID: 27111771; PMCID: PMC5599158.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    42. The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 01; 25(1):76-84. Antony B, Driban JB, Price LL, Lo GH, Ward RJ, Nevitt M, Lynch J, Eaton CB, Ding C, McAlindon TE. PMID: 27539889; PMCID: PMC5310282.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    43. Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic knee osteoarthritis than in isolated medial compartment disease - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2017 01; 25(1):85-93. Wise BL, Niu J, Guermazi A, Liu F, Heilmeier U, Ku E, Lynch JA, Zhang Y, Felson DT, Kwoh CK, Lane NE. PMID: 27539891; PMCID: PMC5182174.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Relation of Step Length to Magnetic Resonance Imaging-Detected Structural Damage in the Patellofemoral Joint: The Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken). 2016 06; 68(6):776-83. Stefanik JJ, Gross KD, Guermazi A, Felson DT, Roemer FW, Niu J, Lynch JA, Segal NA, Lewis CE, Lewis CL. PMID: 26413842; PMCID: PMC4809780.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    45. Defining and evaluating a novel outcome measure representing end-stage knee osteoarthritis: data from the Osteoarthritis Initiative. Clin Rheumatol. 2016 Oct; 35(10):2523-30. Driban JB, Price LL, Lynch J, Nevitt M, Lo GH, Eaton CB, McAlindon TE. PMID: 27184045; PMCID: PMC5033669.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    46. Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal signature analysis in the MOST study. Osteoarthritis Cartilage. 2016 10; 24(10):1736-1744. Podsiadlo P, Nevitt MC, Wolski M, Stachowiak GW, Lynch JA, Tolstykh I, Felson DT, Segal NA, Lewis CE, Englund M. PMID: 27163445; PMCID: PMC5482364.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    47. The association of distal femur and proximal tibia shape with sex: The Osteoarthritis Initiative. Semin Arthritis Rheum. 2016 08; 46(1):20-6. Wise BL, Liu F, Kritikos L, Lynch JA, Parimi N, Zhang Y, Lane NE. PMID: 27039962; PMCID: PMC4969176.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Variations in Hip Shape Are Associated with Radiographic Knee Osteoarthritis: Cross-sectional and Longitudinal Analyses of the Johnston County Osteoarthritis Project. J Rheumatol. 2016 Feb; 43(2):405-10. Nelson AE, Golightly YM, Renner JB, Schwartz TA, Liu F, Lynch JA, Gregory JS, Aspden RM, Lane NE, Jordan JM. PMID: 26669914; PMCID: PMC4738023.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    49. Brief Report: Cartilage Thickness Change as an Imaging Biomarker of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium. Arthritis Rheumatol. 2015 Dec; 67(12):3184-9. Eckstein F, Collins JE, Nevitt MC, Lynch JA, Kraus VB, Katz JN, Losina E, Wirth W, Guermazi A, Roemer FW, Hunter DJ, FNIH OA Biomarkers Consortium. PMID: 26316262; PMCID: PMC5495918.
      View in: PubMed   Mentions: 58     Fields:    Translation:Humans
    50. Novel statistical methodology reveals that hip shape is associated with incident radiographic hip osteoarthritis among African American women. Osteoarthritis Cartilage. 2016 Apr; 24(4):640-6. An H, Marron JS, Schwartz TA, Renner JB, Liu F, Lynch JA, Lane NE, Jordan JM, Nelson AE. PMID: 26620089; PMCID: PMC4799754.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    51. Do persons with asymmetric hip pain or radiographic hip OA have worse pain and structure outcomes in the knee opposite the more affected hip? Data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 Mar; 24(3):427-35. Joseph GB, Hilton JF, Jungmann PM, Lynch JA, Lane NE, Liu F, McCulloch CE, Tolstykh I, Link TM, Nevitt MC. PMID: 26497607; PMCID: PMC4761312.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    52. Longitudinal validation of periarticular bone area and 3D shape as biomarkers for knee OA progression? Data from the FNIH OA Biomarkers Consortium. Ann Rheum Dis. 2016 Sep; 75(9):1607-14. Hunter D, Nevitt M, Lynch J, Kraus VB, Katz JN, Collins JE, Bowes M, Guermazi A, Roemer FW, Losina E, FNIH OA Biomarkers Consortium. PMID: 26483253.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    53. Association of Physical Activity Measured by Accelerometer, Knee Joint Abnormalities, and Cartilage T2 Measurements Obtained From 3T Magnetic Resonance Imaging: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2015 Sep; 67(9):1272-1280. Kretzschmar M, Lin W, Nardo L, Joseph GB, Dunlop DD, Heilmeier U, Nevitt MC, Alizai H, McCulloch CE, Lynch JA, Link TM. PMID: 25777255; PMCID: PMC4573366.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    54. Multi-dimensional reliability assessment of fractal signature analysis in an outpatient sports medicine population. Ann Anat. 2015 Nov; 202:57-60. Jarraya M, Guermazi A, Niu J, Duryea J, Lynch JA, Roemer FW. PMID: 26343866.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    55. Diagnostic performance of 3D standing CT imaging for detection of knee osteoarthritis features. Phys Sportsmed. 2015 Aug 3; 1-8. Segal NA, Nevitt MC, Lynch JA, Niu J, Torner JC, Guermazi A. PMID: 26235750.
      View in: PubMed   Mentions:
    56. Diagnostic performance of 3D standing CT imaging for detection of knee osteoarthritis features. Phys Sportsmed. 2015 Jul; 43(3):213-20. Segal NA, Nevitt MC, Lynch JA, Niu J, Torner JC, Guermazi A. PMID: 26313455; PMCID: PMC4818011.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    57. Knee joint subchondral bone structure alterations in active athletes: a cross-sectional case-control study. Osteoarthritis Cartilage. 2015 Dec; 23(12):2184-2190. Roemer FW, Jarraya M, Niu J, Duryea J, Lynch JA, Guermazi A. PMID: 26187571.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    58. Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis Study (MOST). Osteoarthritis Cartilage. 2015 Sep; 23(9):1491-8. Sheehy L, Culham E, McLean L, Niu J, Lynch J, Segal NA, Singh JA, Nevitt M, Cooke TD. PMID: 26003948; PMCID: PMC4831715.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Severe radiographic knee osteoarthritis--does Kellgren and Lawrence grade 4 represent end stage disease?--the MOST study. Osteoarthritis Cartilage. 2015 Sep; 23(9):1499-505. Guermazi A, Hayashi D, Roemer F, Felson DT, Wang K, Lynch J, Amin S, Torner J, Lewis CE, Nevitt MC. PMID: 25929973; PMCID: PMC4558267.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    60. A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2015 Jun; 23(6):897-905. Joseph GB, McCulloch CE, Nevitt MC, Heilmeier U, Nardo L, Lynch JA, Liu F, Baum T, Link TM. PMID: 25680652; PMCID: PMC4444394.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    61. Association of cartilage degeneration with four year weight gain--3T MRI data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2015 Apr; 23(4):525-31. Bucknor MD, Nardo L, Joseph GB, Alizai H, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. PMID: 25591445; PMCID: PMC4368476.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    62. CT imaging for evaluation of calcium crystal deposition in the knee: initial experience from the Multicenter Osteoarthritis (MOST) study. Osteoarthritis Cartilage. 2015 Feb; 23(2):244-8. Misra D, Guermazi A, Sieren JP, Lynch J, Torner J, Neogi T, Felson DT. PMID: 25451303; PMCID: PMC4305039.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    63. Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing in persons with knee OA--the MOST study. Osteoarthritis Cartilage. 2014 Oct; 22(10):1743-7. Crema MD, Nevitt MC, Guermazi A, Felson DT, Wang K, Lynch JA, Marra MD, Torner J, Lewis CE, Roemer FW. PMID: 25278083; PMCID: PMC4187213.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    64. A new method to measure anatomic knee alignment for large studies of OA: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2014 Oct; 22(10):1668-74. Iranpour-Boroujeni T, Li J, Lynch JA, Nevitt M, Duryea J, OAI Investigators. PMID: 25278076.
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    65. Proximal femur shape differs between subjects with lateral and medial knee osteoarthritis and controls: the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2014 Dec; 22(12):2067-73. Wise BL, Kritikos L, Lynch JA, Liu F, Parimi N, Tileston KL, Nevitt MC, Lane NE. PMID: 25194496; PMCID: PMC4252863.
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    66. Scoring hip osteoarthritis with MRI (SHOMRI): A whole joint osteoarthritis evaluation system. J Magn Reson Imaging. 2015 Jun; 41(6):1549-57. Lee S, Nardo L, Kumar D, Wyatt CR, Souza RB, Lynch J, McCulloch CE, Majumdar S, Lane NE, Link TM. PMID: 25139720; PMCID: PMC4336224.
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    67. Association of hip and pelvic geometry with tibiofemoral osteoarthritis: multicenter osteoarthritis study (MOST). Osteoarthritis Cartilage. 2014 Aug; 22(8):1129-35. Boissonneault A, Lynch JA, Wise BL, Segal NA, Gross KD, Murray DW, Nevitt MC, Pandit HG. PMID: 24971867; PMCID: PMC4195737.
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    68. Weight loss over 48 months is associated with reduced progression of cartilage T2 relaxation time values: data from the osteoarthritis initiative. J Magn Reson Imaging. 2015 May; 41(5):1272-1280. Serebrakian AT, Poulos T, Liebl H, Joseph GB, Lai A, Nevitt MC, Lynch JA, McCulloch CE, Link TM. PMID: 24700497; PMCID: PMC4185274.
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    69. Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative. Ann Rheum Dis. 2015 Jul; 74(7):1353-9. Liebl H, Joseph G, Nevitt MC, Singh N, Heilmeier U, Subburaj K, Jungmann PM, McCulloch CE, Lynch JA, Lane NE, Link TM. PMID: 24615539; PMCID: PMC4160419.
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    70. Cartilage lesion score: comparison of a quantitative assessment score with established semiquantitative MR scoring systems. Radiology. 2014 May; 271(2):479-87. Alizai H, Virayavanich W, Joseph GB, Nardo L, Liu F, Liebl H, Nevitt MC, Lynch JA, McCulloch CE, Link TM. PMID: 24475848; PMCID: PMC4263635.
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    71. Synovitis in knee osteoarthritis assessed by contrast-enhanced magnetic resonance imaging (MRI) is associated with radiographic tibiofemoral osteoarthritis and MRI-detected widespread cartilage damage: the MOST study. J Rheumatol. 2014 Mar; 41(3):501-8. Guermazi A, Hayashi D, Roemer FW, Zhu Y, Niu J, Crema MD, Javaid MK, Marra MD, Lynch JA, El-Khoury GY, Zhang Y, Nevitt MC, Felson DT. PMID: 24429179; PMCID: PMC5476295.
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    72. Association of incident symptomatic hip osteoarthritis with differences in hip shape by active shape modeling: the Johnston County Osteoarthritis Project. Arthritis Care Res (Hoboken). 2014 Jan; 66(1):74-81. Nelson AE, Liu F, Lynch JA, Renner JB, Schwartz TA, Lane NE, Jordan JM. PMID: 23926053; PMCID: PMC3959908.
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    73. Association of metabolic risk factors with cartilage degradation assessed by T2 relaxation time at the knee: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):1942-50. Jungmann PM, Kraus MS, Alizai H, Nardo L, Baum T, Nevitt MC, McCulloch CE, Joseph GB, Lynch JA, Link TM. PMID: 23926027; PMCID: PMC4144858.
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    74. Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2014 Jan; 22(1):63-70. Wirth W, Nevitt M, Hellio Le Graverand MP, Lynch J, Maschek S, Hudelmaier M, Eckstein F, OA Initiative Investigators Group. PMID: 24185111; PMCID: PMC4054605.
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    75. T(2) relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging. 2013 Dec; 38(6):1415-24. Jungmann PM, Kraus MS, Nardo L, Liebl H, Alizai H, Joseph GB, Liu F, Lynch J, McCulloch CE, Nevitt MC, Link TM. PMID: 24038491; PMCID: PMC4114220.
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    76. Association of frequent knee bending activity with focal knee lesions detected with 3T magnetic resonance imaging: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Sep; 65(9):1441-8. Virayavanich W, Alizai H, Baum T, Nardo L, Nevitt MC, Lynch JA, McCulloch CE, Link TM. PMID: 23554229; PMCID: PMC4118638.
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    77. Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013 Oct; 21(10):1558-66. Lin W, Alizai H, Joseph GB, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. PMID: 23831632; PMCID: PMC3874212.
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    78. Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skeletal Radiol. 2013 Oct; 42(10):1383-92. Jungmann PM, Tham SC, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link TM. PMID: 23801099; PMCID: PMC3757255.
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    79. Medial posterior meniscal root tears are associated with development or worsening of medial tibiofemoral cartilage damage: the multicenter osteoarthritis study. Radiology. 2013 Sep; 268(3):814-21. Guermazi A, Hayashi D, Jarraya M, Roemer FW, Zhang Y, Niu J, Crema MD, Englund M, Lynch JA, Nevitt MC, Torner JC, Lewis CE, Felson DT. PMID: 23696679; PMCID: PMC3750419.
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    80. Association between measures of patella height, morphologic features of the trochlea, and patellofemoral joint alignment: the MOST study. Clin Orthop Relat Res. 2013 Aug; 471(8):2641-8. Stefanik JJ, Zumwalt AC, Segal NA, Lynch JA, Powers CM. PMID: 23546847; PMCID: PMC3705075.
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    81. Focal knee lesions in knee pairs of asymptomatic and symptomatic subjects with OA risk factors--data from the Osteoarthritis Initiative. Eur J Radiol. 2013 Aug; 82(8):e367-73. Chundru R, Baum T, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 23540944; PMCID: PMC3696431.
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    82. Quantification of bone marrow lesion volume and volume change using semi-automated segmentation: data from the osteoarthritis initiative. BMC Musculoskelet Disord. 2013 Jan 02; 14:3. Pang J, Driban JB, Destenaves G, Miller E, Lo GH, Ward RJ, Price LL, Lynch JA, Eaton CB, Eckstein F, McAlindon TE. PMID: 23281825; PMCID: PMC3637109.
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    83. Bone marrow lesion volume reduction is not associated with improvement of other periarticular bone measures: data from the Osteoarthritis Initiative. Arthritis Res Ther. 2013; 15(5):R153. Driban JB, Lo GH, Price L, Pang J, Miller E, Ward RJ, Hunter DJ, Eaton CB, Lynch JA, McAlindon TE, OAI Investigators Group. PMID: 24432365; PMCID: PMC3978480.
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    84. Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study. Arthritis Care Res (Hoboken). 2013 Jan; 65(1):23-33. Baum T, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 22623435; PMCID: PMC3432679.
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    85. Evaluation of bone marrow lesion volume as a knee osteoarthritis biomarker--longitudinal relationships with pain and structural changes: data from the Osteoarthritis Initiative. Arthritis Res Ther. 2013; 15(5):R112. Driban JB, Price L, Lo GH, Pang J, Hunter DJ, Miller E, Ward RJ, Eaton CB, Lynch JA, McAlindon TE. PMID: 24020939; PMCID: PMC3978948.
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    86. Peripatellar synovitis: comparison between non-contrast-enhanced and contrast-enhanced MRI and association with pain. The MOST study. Osteoarthritis Cartilage. 2013 Mar; 21(3):413-8. Crema MD, Felson DT, Roemer FW, Niu J, Marra MD, Zhang Y, Lynch JA, El-Khoury GY, Lewis CE, Guermazi A. PMID: 23277189; PMCID: PMC3578385.
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    87. The association between meniscal damage of the posterior horns and localized posterior synovitis detected on T1-weighted contrast-enhanced MRI--the MOST study. Semin Arthritis Rheum. 2013 Jun; 42(6):573-81. Roemer FW, Felson DT, Yang T, Niu J, Crema MD, Englund M, Nevitt MC, Zhang Y, Lynch JA, El Khoury GY, Torner J, Lewis CE, Guermazi A. PMID: 23270763; PMCID: PMC3640766.
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    88. Prevalent cartilage damage and cartilage loss over time are associated with incident bone marrow lesions in the tibiofemoral compartments: the MOST study. Osteoarthritis Cartilage. 2013 Feb; 21(2):306-13. Crema MD, Felson DT, Roemer FW, Wang K, Marra MD, Nevitt MC, Lynch JA, Torner J, Lewis CE, Guermazi A. PMID: 23178289; PMCID: PMC3556203.
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    89. Reliability of semiautomated computational methods for estimating tibiofemoral contact stress in the Multicenter Osteoarthritis Study. Comput Math Methods Med. 2012; 2012:767469. Anderson DD, Segal NA, Kern AM, Nevitt MC, Torner JC, Lynch JA. PMID: 23097679; PMCID: PMC3477762.
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    90. Lumbosacral transitional vertebrae: association with low back pain. Radiology. 2012 Nov; 265(2):497-503. Nardo L, Alizai H, Virayavanich W, Liu F, Hernandez A, Lynch JA, Nevitt MC, McCulloch CE, Lane NE, Link TM. PMID: 22952380; PMCID: PMC3480814.
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    91. Bone marrow lesions are associated with altered trabecular morphometry. Osteoarthritis Cartilage. 2012 Dec; 20(12):1519-26. Driban JB, Tassinari A, Lo GH, Price LL, Schneider E, Lynch JA, Eaton CB, McAlindon TE, OAI Investigators Group. PMID: 22940708; PMCID: PMC3478500.
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    92. Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral joint--the MOST study. Osteoarthritis Cartilage. 2012 Nov; 20(11):1391-8. Roemer FW, Nevitt MC, Felson DT, Niu J, Lynch JA, Crema MD, Lewis CE, Torner J, Guermazi A. PMID: 22846715; PMCID: PMC3863692.
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    93. How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2012 Nov; 20(11):1250-7. Eckstein F, Mc Culloch CE, Lynch JA, Nevitt M, Kwoh CK, Maschek S, Hudelmaier M, Sharma L, Wirth W, OA Initiative Investigators Group. PMID: 22800771; PMCID: PMC3471368.
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    94. Elevated tibiofemoral articular contact stress predicts risk for bone marrow lesions and cartilage damage at 30 months. Osteoarthritis Cartilage. 2012 Oct; 20(10):1120-6. Segal NA, Kern AM, Anderson DD, Niu J, Lynch J, Guermazi A, Torner JC, Brown TD, Nevitt M, Multicenter Osteoarthritis Study Group. PMID: 22698440; PMCID: PMC3427397.
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    95. Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis. Arthritis Rheum. 2012 May; 64(5):1457-65. Baker-Lepain JC, Lynch JA, Parimi N, McCulloch CE, Nevitt MC, Corr M, Lane NE. PMID: 22544526; PMCID: PMC3340442.
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    96. The role of varus and valgus alignment in the initial development of knee cartilage damage by MRI: the MOST study. Ann Rheum Dis. 2013 Feb; 72(2):235-40. Sharma L, Chmiel JS, Almagor O, Felson D, Guermazi A, Roemer F, Lewis CE, Segal N, Torner J, Cooke TD, Hietpas J, Lynch J, Nevitt M. PMID: 22550314; PMCID: PMC3845483.
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    97. Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2012 Jul; 20(7):727-35. Joseph GB, Baum T, Alizai H, Carballido-Gamio J, Nardo L, Virayavanich W, Lynch JA, Nevitt MC, McCulloch CE, Majumdar S, Link TM. PMID: 22503812; PMCID: PMC3595156.
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    98. Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):248-55. Baum T, Joseph GB, Arulanandan A, Nardo L, Virayavanich W, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 22012846; PMCID: PMC3267009.
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    99. Changes in knee cartilage T2 values over 24 months in subjects with and without risk factors for knee osteoarthritis and their association with focal knee lesions at baseline: data from the osteoarthritis initiative. J Magn Reson Imaging. 2012 Feb; 35(2):370-8. Baum T, Stehling C, Joseph GB, Carballido-Gamio J, Schwaiger BJ, Müller-Höcker C, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 21987496; PMCID: PMC3265616.
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    100. Quadriceps weakness, patella alta, and structural features of patellofemoral osteoarthritis. Arthritis Care Res (Hoboken). 2011 Oct; 63(10):1391-7. Stefanik JJ, Guermazi A, Zhu Y, Zumwalt AC, Gross KD, Clancy M, Lynch JA, Segal NA, Lewis CE, Roemer FW, Powers CM, Felson DT. PMID: 21702087; PMCID: PMC3183313.
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    101. Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls--data from the osteoarthritis initiative. Arthritis Res Ther. 2011; 13(5):R153. Joseph GB, Baum T, Carballido-Gamio J, Nardo L, Virayavanich W, Alizai H, Lynch JA, McCulloch CE, Majumdar S, Link TM. PMID: 21933394; PMCID: PMC3308083.
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    102. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects--data from the Osteoarthritis Initiative. Skeletal Radiol. 2012 Jun; 41(6):633-41. Laberge MA, Baum T, Virayavanich W, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 21887596; PMCID: PMC4105189.
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    103. Physical activity is associated with magnetic resonance imaging-based knee cartilage T2 measurements in asymptomatic subjects with and those without osteoarthritis risk factors. Arthritis Rheum. 2011 Aug; 63(8):2248-56. Hovis KK, Stehling C, Souza RB, Haughom BD, Baum T, Nevitt M, McCulloch C, Lynch JA, Link TM. PMID: 21538328; PMCID: PMC3149726.
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    104. Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study. Ann Rheum Dis. 2011 Oct; 70(10):1804-9. Roemer FW, Guermazi A, Felson DT, Niu J, Nevitt MC, Crema MD, Lynch JA, Lewis CE, Torner J, Zhang Y. PMID: 21791448; PMCID: PMC3496084.
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    105. Association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: the MOST study. J Orthop Res. 2012 Jan; 30(1):1-8. Stefanik JJ, Roemer FW, Zumwalt AC, Zhu Y, Gross KD, Lynch JA, Frey-Law LA, Lewis CE, Guermazi A, Powers CM, Felson DT. PMID: 21710542; PMCID: PMC3217080.
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    106. Risk factors for medial meniscal pathology on knee MRI in older US adults: a multicentre prospective cohort study. Ann Rheum Dis. 2011 Oct; 70(10):1733-9. Englund M, Felson DT, Guermazi A, Roemer FW, Wang K, Crema MD, Lynch JA, Sharma L, Segal NA, Lewis CE, Nevitt MC. PMID: 21646417; PMCID: PMC4864962.
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    107. Active shape modeling of the hip in the prediction of incident hip fracture. J Bone Miner Res. 2011 Mar; 26(3):468-74. Baker-LePain JC, Luker KR, Lynch JA, Parimi N, Nevitt MC, Lane NE. PMID: 20878772; PMCID: PMC3179295.
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    108. Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST study. Ann Rheum Dis. 2011 May; 70(5):805-11. Guermazi A, Roemer FW, Hayashi D, Crema MD, Niu J, Zhang Y, Marra MD, Katur A, Lynch JA, El-Khoury GY, Baker K, Hughes LB, Nevitt MC, Felson DT. PMID: 21187293; PMCID: PMC4180232.
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    109. Longitudinal analysis of MRI T2 knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative: a texture approach. Magn Reson Med. 2011 Apr; 65(4):1184-94. Carballido-Gamio J, Joseph GB, Lynch JA, Link TM, Majumdar S. PMID: 21413082.
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    110. Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T MRI - an analysis from the incidence cohort of the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011 Jan; 19(1):65-73. Pan J, Stehling C, Muller-Hocker C, Schwaiger BJ, Lynch J, McCulloch CE, Nevitt MC, Link TM. PMID: 21044692; PMCID: PMC3027210.
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    111. Does measurement of the anatomic axis consistently predict hip-knee-ankle angle (HKA) for knee alignment studies in osteoarthritis? Analysis of long limb radiographs from the multicenter osteoarthritis (MOST) study. Osteoarthritis Cartilage. 2011 Jan; 19(1):58-64. Sheehy L, Felson D, Zhang Y, Niu J, Lam YM, Segal N, Lynch J, Cooke TD. PMID: 20950695; PMCID: PMC3038654.
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    112. Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2010 Nov; 18(11):1386-92. Guermazi A, Hayashi D, Roemer FW, Niu J, Yang M, Lynch JA, Torner JC, Lewis CE, Sack B, Felson DT, Nevitt MC. PMID: 20816978; PMCID: PMC2975853.
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    113. Comparison of BLOKS and WORMS scoring systems part II. Longitudinal assessment of knee MRIs for osteoarthritis and suggested approach based on their performance: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2010 Nov; 18(11):1402-7. Felson DT, Lynch J, Guermazi A, Roemer FW, Niu J, McAlindon T, Nevitt MC. PMID: 20851202; PMCID: PMC3005331.
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    114. Comparison of BLOKS and WORMS scoring systems part I. Cross sectional comparison of methods to assess cartilage morphology, meniscal damage and bone marrow lesions on knee MRI: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2010 Nov; 18(11):1393-401. Lynch JA, Roemer FW, Nevitt MC, Felson DT, Niu J, Eaton CB, Guermazi A. PMID: 20816979; PMCID: PMC3055245.
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    115. Association between patella alta and the prevalence and worsening of structural features of patellofemoral joint osteoarthritis: the multicenter osteoarthritis study. Arthritis Care Res (Hoboken). 2010 Sep; 62(9):1258-65. Stefanik JJ, Zhu Y, Zumwalt AC, Gross KD, Clancy M, Lynch JA, Frey Law LA, Lewis CE, Roemer FW, Powers CM, Guermazi A, Felson DT. PMID: 20506169; PMCID: PMC2943040.
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    116. Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging--the MOST study. Radiology. 2010 Sep; 256(3):855-62. Crema MD, Roemer FW, Zhu Y, Marra MD, Niu J, Zhang Y, Lynch JA, Javaid MK, Lewis CE, El-Khoury GY, Felson DT, Guermazi A. PMID: 20530753; PMCID: PMC2923728.
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    117. Varus and valgus alignment and incident and progressive knee osteoarthritis. Ann Rheum Dis. 2010 Nov; 69(11):1940-5. Sharma L, Song J, Dunlop D, Felson D, Lewis CE, Segal N, Torner J, Cooke TD, Hietpas J, Lynch J, Nevitt M. PMID: 20511608; PMCID: PMC2994600.
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    118. Implementation of discrete element analysis for subject-specific, population-wide investigations of habitual contact stress exposure. J Appl Biomech. 2010 May; 26(2):215-23. Anderson DD, Iyer KS, Segal NA, Lynch JA, Brown TD. PMID: 20498493; PMCID: PMC2905528.
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    119. Meniscal pathology on MRI increases the risk for both incident and enlarging subchondral bone marrow lesions of the knee: the MOST Study. Ann Rheum Dis. 2010 Oct; 69(10):1796-802. Englund M, Guermazi A, Roemer FW, Yang M, Zhang Y, Nevitt MC, Lynch JA, Lewis CE, Torner J, Felson DT. PMID: 20421344; PMCID: PMC2966967.
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    120. Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis initiative. Osteoarthritis Cartilage. 2010 Jun; 18(6):776-86. Stehling C, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 20202488; PMCID: PMC4839980.
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    121. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative. Magn Reson Med. 2010 Feb; 63(2):465-72. Carballido-Gamio J, Blumenkrantz G, Lynch JA, Link TM, Majumdar S. PMID: 19918905; PMCID: PMC6348066.
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    122. Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology. 2010 Feb; 254(2):509-20. Stehling C, Liebl H, Krug R, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. PMID: 20019141; PMCID: PMC2809928.
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    123. Baseline articular contact stress levels predict incident symptomatic knee osteoarthritis development in the MOST cohort. J Orthop Res. 2009 Dec; 27(12):1562-8. Segal NA, Anderson DD, Iyer KS, Baker J, Torner JC, Lynch JA, Felson DT, Lewis CE, Brown TD. PMID: 19533741; PMCID: PMC2981407.
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    124. Cartilage loss occurs in the same subregions as subchondral bone attrition: a within-knee subregion-matched approach from the Multicenter Osteoarthritis Study. Arthritis Rheum. 2009 Nov 15; 61(11):1539-44. Neogi T, Felson D, Niu J, Lynch J, Nevitt M, Guermazi A, Roemer F, Lewis CE, Wallace B, Zhang Y. PMID: 19877101; PMCID: PMC2789549.
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    125. Pre-radiographic MRI findings are associated with onset of knee symptoms: the most study. Osteoarthritis Cartilage. 2010 Mar; 18(3):323-8. Javaid MK, Lynch JA, Tolstykh I, Guermazi A, Roemer F, Aliabadi P, McCulloch C, Curtis J, Felson D, Lane NE, Torner J, Nevitt M. PMID: 19919856; PMCID: PMC2990960.
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    126. Contrast-enhanced MRI of subchondral cysts in patients with or at risk for knee osteoarthritis: the MOST study. Eur J Radiol. 2010 Jul; 75(1):e92-6. Crema MD, Roemer FW, Marra MD, Niu J, Lynch JA, Felson DT, Guermazi A. PMID: 19767165; PMCID: PMC2891222.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    127. Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study. Osteoarthritis Cartilage. 2010 Jan; 18(1):47-53. Roemer FW, Neogi T, Nevitt MC, Felson DT, Zhu Y, Zhang Y, Lynch JA, Javaid MK, Crema MD, Torner J, Lewis CE, Guermazi A. PMID: 19769930; PMCID: PMC2818146.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    128. A comparison of dedicated 1.0 T extremity MRI vs large-bore 1.5 T MRI for semiquantitative whole organ assessment of osteoarthritis: the MOST study. Osteoarthritis Cartilage. 2010 Feb; 18(2):168-74. Roemer FW, Lynch JA, Niu J, Zhang Y, Crema MD, Tolstykh I, El-Khoury GY, Felson DT, Lewis CE, Nevitt MC, Guermazi A. PMID: 19766580; PMCID: PMC2818134.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    129. Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology. 2009 Sep; 252(3):772-80. Roemer FW, Zhang Y, Niu J, Lynch JA, Crema MD, Marra MD, Nevitt MC, Felson DT, Hughes LB, El-Khoury GY, Englund M, Guermazi A, Multicenter Osteoarthritis Study Investigators. PMID: 19635831; PMCID: PMC2734891.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    130. The association of proximal femoral shape and incident radiographic hip OA in elderly women. Osteoarthritis Cartilage. 2009 Oct; 17(10):1313-8. Lynch JA, Parimi N, Chaganti RK, Nevitt MC, Lane NE, Study of Osteoporotic Fractures Research Group. PMID: 19427402; PMCID: PMC3678721.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    131. Strong association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2009 Jun; 17(6):743-7. Lo GH, Hunter DJ, Nevitt M, Lynch J, McAlindon TE, OAI Investigators Group. PMID: 19097919; PMCID: PMC2771759.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    132. The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies. Osteoarthritis Cartilage. 2009 Jun; 17(6):748-53. Roemer FW, Guermazi A, Hunter DJ, Niu J, Zhang Y, Englund M, Javaid MK, Lynch JA, Mohr A, Torner J, Lewis CE, Nevitt MC, Felson DT. PMID: 19008123; PMCID: PMC2740855.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    133. Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study. A longitudinal multicentre study of knee osteoarthritis. Ann Rheum Dis. 2009 Sep; 68(9):1461-5. Roemer FW, Guermazi A, Javaid MK, Lynch JA, Niu J, Zhang Y, Felson DT, Lewis CE, Torner J, Nevitt MC, MOST Study investigators. PMID: 18829615; PMCID: PMC2905622.
      View in: PubMed   Mentions: 128     Fields:    Translation:Humans
    134. Effect of meniscal damage on the development of frequent knee pain, aching, or stiffness. Arthritis Rheum. 2007 Dec; 56(12):4048-54. Englund M, Niu J, Guermazi A, Roemer FW, Hunter DJ, Lynch JA, Lewis CE, Torner J, Nevitt MC, Zhang YQ, Felson DT. PMID: 18050201.
      View in: PubMed   Mentions: 55     Fields:    Translation:Humans
    135. Micro-CT arthrography: a pilot study for the ex vivo visualization of the rat knee joint. AJR Am J Roentgenol. 2005 Apr; 184(4):1215-9. Roemer FW, Mohr A, Lynch JA, Meta MD, Guermazi A, Genant HK. PMID: 15788597.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    136. Short tau inversion recovery and proton density-weighted fat suppressed sequences for the evaluation of osteoarthritis of the knee with a 1.0 T dedicated extremity MRI: development of a time-efficient sequence protocol. Eur Radiol. 2005 May; 15(5):978-87. Roemer FW, Guermazi A, Lynch JA, Peterfy CG, Nevitt MC, Webb N, Li J, Mohr A, Genant HK, Felson DT. PMID: 15633060.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    137. Imaging of bone erosion in rheumatoid arthritis. Semin Musculoskelet Radiol. 2004 Dec; 8(4):269-85. Guermazi A, Taouli B, Lynch JA, Peterfy CG. PMID: 15643569.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    138. Quantification of bone lesions in rheumatoid arthritis by MRI multispectral tissue class transition analysis. Semin Musculoskelet Radiol. 2004 Dec; 8(4):301-11. Carano RA, Lynch JA. PMID: 15643571.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    139. Micro-CT of carotid arteries: a tool for experimental studies. Cardiovasc Intervent Radiol. 2004 Nov-Dec; 27(6):651-4. Mohr A, Wenke R, Roemer FW, Lynch JA, Gatzka C, Priebe M, Guermazi A, Grigorian M, Heller M, Mueller-Huelsbeck S. PMID: 15593429.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    140. Femoral neck trabecular microstructure in ovariectomized ewes treated with calcitonin: MRI microscopic evaluation. J Bone Miner Res. 2005 Jan; 20(1):125-30. Jiang Y, Zhao J, Geusens P, Liao EY, Adriaensens P, Gelan J, Azria M, Boonen S, Caulin F, Lynch JA, Ouyang X, Genant HK. PMID: 15619678.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    141. Multispectral analysis of bone lesions in the hands of patients with rheumatoid arthritis. Magn Reson Imaging. 2004 May; 22(4):505-14. Carano RA, Lynch JA, Redei J, Ostrowitzki S, Miaux Y, Zaim S, White DL, Peterfy CG, Genant HK. PMID: 15120170.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    142. Rheumatoid arthritis of the hand and wrist: comparison of three imaging techniques. AJR Am J Roentgenol. 2004 Apr; 182(4):937-43. Taouli B, Zaim S, Peterfy CG, Lynch JA, Stork A, Guermazi A, Fan B, Fye KH, Genant HK. PMID: 15039167.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    143. Measurement of changes in trabecular bone at fracture sites using X-ray CT and automated image registration and processing. J Orthop Res. 2004 Mar; 22(2):362-7. Lynch JA, Grigoryan M, Fierlinger A, Guermazi A, Zaim S, MacLean DB, Genant HK. PMID: 15013097.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    144. Use of multispectral magnetic resonance imaging analysis to quantify erosive changes in the hands of patients with rheumatoid arthritis: short-term and long-term longitudinal studies. Arthritis Rheum. 2004 Mar; 50(3):716-24. Ostrowitzki S, Rédei J, Lynch JA, Carano RA, Zaim S, Miaux Y, Genant HK. PMID: 15022310.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    145. Quantitative and qualitative assessment of closed fracture healing using computed tomography and conventional radiography. Acad Radiol. 2003 Nov; 10(11):1267-73. Grigoryan M, Lynch JA, Fierlinger AL, Guermazi A, Fan B, MacLean DB, MacLean A, Genant HK. PMID: 14626301.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    146. Value of micro-CT as an investigative tool for osteochondritis dissecans. Acta Radiol. 2003 Sep; 44(5):532-7. Mohr A, Heiss C, Bergmann I, Schrader C, Roemer FW, Lynch JA, Muhle C, Genant HK, Heller M. PMID: 14510761.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    147. Digital tomosynthesis of hand joints for arthritis assessment. Med Phys. 2003 Mar; 30(3):325-33. Duryea J, Dobbins JT, Lynch JA. PMID: 12674232.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    148. Comparison of fixed-flexion positioning with fluoroscopic semi-flexed positioning for quantifying radiographic joint-space width in the knee: test-retest reproducibility. Skeletal Radiol. 2003 Mar; 32(3):128-32. Peterfy C, Li J, Zaim S, Duryea J, Lynch J, Miaux Y, Yu W, Genant HK. PMID: 12605275.
      View in: PubMed   Mentions: 152     Fields:    Translation:Humans
    149. Early radiographic features in patients with anterior cruciate ligament rupture. Ann Rheum Dis. 2000 Aug; 59(8):641-6. Buckland-Wright JC, Lynch JA, Dave B. PMID: 10913063; PMCID: PMC1753209.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    150. A comparison of two nickel-titanium instrumentation techniques in teeth using microcomputed tomography. Int Endod J. 2000 May; 33(3):279-85. Rhodes JS, Ford TR, Lynch JA, Liepins PJ, Curtis RV. PMID: 11307448.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    151. Field test of the reproducibility of automated measurements of medial tibiofemoral joint space width derived from standardized knee radiographs. J Rheumatol. 1999 Jun; 26(6):1359-65. Mazzuca SA, Brandt KD, Buckland-Wright JC, Buckwalter KA, Katz BP, Lynch JA, Ward RJ, Emsley CL. PMID: 10381056.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    152. Micro-computed tomography: a new tool for experimental endodontology. Int Endod J. 1999 May; 32(3):165-70. Rhodes JS, Ford TR, Lynch JA, Liepins PJ, Curtis RV. PMID: 10530203.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    153. Microfocal techniques in quantitative radiography: measurement of cancellous bone organization. Br J Rheumatol. 1996 Dec; 35 Suppl 3:18-22. Buckland-Wright JC, Lynch JA, Bird C. PMID: 9010084.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    154. Fractal signature analysis measures cancellous bone organisation in macroradiographs of patients with knee osteoarthritis. Ann Rheum Dis. 1996 Oct; 55(10):749-55. Buckland-Wright JC, Lynch JA, Macfarlane DG. PMID: 8984941; PMCID: PMC1010294.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    155. Sensitivity of radiographic features and specificity of scintigraphic imaging in hand osteoarthritis. Rev Rhum Engl Ed. 1995 Jun; 62(6 Suppl 1):14S-26S. Buckland-Wright JC, Macfarlane DG, Lynch JA. PMID: 7583178.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    156. Quantitative microfocal radiography detects changes in OA knee joint space width in patients in placebo controlled trial of NSAID therapy. J Rheumatol. 1995 May; 22(5):937-43. Buckland-Wright JC, MacFarlane DG, Lynch JA, Jasani MK. PMID: 8587086.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    157. Joint space width measures cartilage thickness in osteoarthritis of the knee: high resolution plain film and double contrast macroradiographic investigation. Ann Rheum Dis. 1995 Apr; 54(4):263-8. Buckland-Wright JC, Macfarlane DG, Lynch JA, Jasani MK, Bradshaw CR. PMID: 7763102; PMCID: PMC1005571.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    158. Quantitative microfocal radiographic assessment of osteoarthritis of the knee from weight bearing tunnel and semiflexed standing views. J Rheumatol. 1994 Sep; 21(9):1734-41. Buckland-Wright JC, Macfarlane DG, Jasani MK, Lynch JA. PMID: 7799359.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    159. Fractal signature analysis of macroradiographs measures trabecular organization in lumbar vertebrae of postmenopausal women. Calcif Tissue Int. 1994 Feb; 54(2):106-12. Buckland-Wright JC, Lynch JA, Rymer J, Fogelman I. PMID: 8012865.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    160. A study of the early and late 99technetium scintigraphic images and their relationship to symptoms in osteoarthritis of the hands. Br J Rheumatol. 1993 Nov; 32(11):977-81. Macfarlane DG, Buckland-Wright JC, Lynch J, Fogelman I. PMID: 8220937.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    161. Precision of joint space width measurement in knee osteoarthritis from digital image analysis of high definition macroradiographs. Osteoarthritis Cartilage. 1993 Oct; 1(4):209-18. Lynch JA, Buckland-Wright JC, Macfarlane DG. PMID: 15449508.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    162. Microfocal radiography with macroradiographs in osteoarthritis. J Rheumatol. 1993 Jun; 20(6):1084-5. Buckland-Wright JC, Macfarlane DG, Lynch JA. PMID: 8350320.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    163. Comparison of the effects of moist and dry conditions on the process of angiogenesis during dermal repair. J Invest Dermatol. 1992 Dec; 99(6):729-33. Dyson M, Young SR, Hart J, Lynch JA, Lang S. PMID: 1281862.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    164. Relationship between joint space width and subchondral sclerosis in the osteoarthritic hand: a quantitative microfocal radiographic study. J Rheumatol. 1992 May; 19(5):788-95. Buckland-Wright JC, MacFarlane DG, Lynch JA. PMID: 1613711.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    165. Comparison of clinical, radionuclide, and radiographic features of osteoarthritis of the hands. Ann Rheum Dis. 1991 Sep; 50(9):623-6. Macfarlane DG, Buckland-Wright JC, Emery P, Fogelman I, Clark B, Lynch J. PMID: 1929584; PMCID: PMC1004505.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    166. Osteophytes in the osteoarthritic hand: their incidence, size, distribution, and progression. Ann Rheum Dis. 1991 Sep; 50(9):627-30. Buckland-Wright JC, Macfarlane DG, Lynch JA. PMID: 1929585; PMCID: PMC1004506.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    167. Analysis of texture in macroradiographs of osteoarthritic knees using the fractal signature. Phys Med Biol. 1991 Jun; 36(6):709-22. Lynch JA, Hawkes DJ, Buckland-Wright JC. PMID: 1871209.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    168. A robust and accurate method for calculating the fractal signature of texture in macroradiographs of osteoarthritic knees. Med Inform (Lond). 1991 Apr-Jun; 16(2):241-51. Lynch JA, Hawkes DJ, Buckland-Wright JC. PMID: 1921566.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    169. Techetium 99m methylene diphosphonate bone scanning in osteoarthritic hands. Eur J Nucl Med. 1991; 18(1):12-6. Buckland-Wright JC, Macfarlane DG, Fogelman I, Emery P, Lynch JA. PMID: 2019277.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    170. Quantitative microfocal radiographic assessment of progression in osteoarthritis of the hand. Arthritis Rheum. 1990 Jan; 33(1):57-65. Buckland-Wright JC, Macfarlane DG, Lynch JA, Clark B. PMID: 2302268.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
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