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John Watson, PhD

Title(s)Professor, Dean's Office
SchoolSchool of Medicine
Address1855 Folsom Street
San Francisco CA 94103
Phone--
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    Collapse Research 
    Collapse Research Activities and Funding
    UCSF CC/SFSU Collaborative--Cancer Research and Training
    NIH/NCI P20CA091430May 1, 2001 - Apr 30, 2004
    Role: Principal Investigator
    DIPTERA MEVALONIC ACID METABOLISM AND REGULATION
    NIH/NIGMS R01GM052623Sep 30, 1994 - Aug 31, 1998
    Role: Principal Investigator
    STEROL DEPENDENT REGULATION OF MEVALONATE SYNTHESIS
    NIH/NHLBI R01HL040445Apr 1, 1988 - Mar 31, 1992
    Role: Principal Investigator
    STEROL INDEPENDENT REGULATION OF HMG-COA REDUCTASE
    NIH/NHLBI R01HL031156Jul 1, 1983 - Sep 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol. Eur J Biochem. 1999 Dec; 266(2):317-26. Plemenitas A, Watson JA. PMID: 10561571.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    2. Regulation of cholesterol metabolism in a slow-growing hepatoma in vivo. Biochim Biophys Acta. 1988 May 22; 960(2):131-8. Erickson SK, Cooper AD, Barnard GF, Havel CM, Watson JA, Feingold KR, Moser AH, Hughes-Fulford M, Siperstein MD. PMID: 2835108.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    3. Isopentenoid synthesis in isolated embryonic Drosophila cells. Possible regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by shunted mevalonate carbon. J Biol Chem. 1986 Aug 05; 261(22):10150-6. Havel C, Rector ER, Watson JA. PMID: 3733706.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. Isoprenoid synthesis in Halobacterium halobium. Modulation of 3-hydroxy-3-methylglutaryl coenzyme a concentration in response to mevalonate availability. J Biol Chem. 1986 Mar 15; 261(8):3578-83. Cabrera JA, Bolds J, Shields PE, Havel CM, Watson JA. PMID: 3633268.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    5. Isoprenoid synthesis in isolated embryonic Drosophila cells. Sterol-independent regulatory signal molecule is distal to isopentenyl 1-pyrophosphates. J Biol Chem. 1985 Nov 15; 260(26):14083-91. Watson JA, Havel CM, Lobos DV, Baker FC, Morrow CJ. PMID: 4055772.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. Isoprene synthesis in isolated embryonic Drosophila cells. I. Sterol-deficient eukaryotic cells. J Biol Chem. 1983 Jul 10; 258(13):8503-11. Silberkang M, Havel CM, Friend DS, McCarthy BJ, Watson JA. PMID: 6863298.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    7. Isoprene synthesis in isolated embryonic Drosophila cells. II. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. J Biol Chem. 1983 Jul 10; 258(13):8512-8. Brown K, Havel CM, Watson JA. PMID: 6863299.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    8. Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation. J Biol Chem. 1979 Oct 10; 254(19):9573-82. Havel C, Hansbury E, Scallen TJ, Watson JA. PMID: 489551.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    9. Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase in minimal deviation hepatoma 7288C. Immunological measurements in hepatoma tissue culture cells. J Biol Chem. 1977 Feb 10; 252(3):950-4. Beirne OR, Heller R, Watson JA. PMID: 190221.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    10. Comparison of regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma cells grown in vivo and in vitro. Proc Natl Acad Sci U S A. 1976 Aug; 73(8):2735-9. Beirne OR, Watson JA. PMID: 183207.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in hepatoma tissue culture cells by pure cholesterol and several cholesterol derivatives. Evidence supporting two distinct mechanisms.20l. J Biol Chem. 1976 Mar 25; 251(6):1745-58. Bell JJ, Sargeant TE, Watson JA. PMID: 176160.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    12. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins. J Biol Chem. 1974 Oct 10; 249(19):6104-9. Kirsten ES, Watson JA. PMID: 4371188.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
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