Jonathan Brunger, PhD

Title(s)Postdoctoral Scholar, Cellular Molecular Pharmacology
SchoolSchool of Medicine
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Duke UniversityPh.D.12/2015Biomedical Engineering
    Duke UniversityM.S.05/2014Biomedical Engineering
    Stanford UniversityB.S.06/2004Engineering

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Engineered Sense and Response Circuits for Stem Cell-Based Tissue Regeneration and Repair
    NIH/NIBIB F32EB024391Apr 1, 2017 - Mar 31, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F. Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds. Tissue Eng Part A. 2018 Oct; 24(19-20):1531-1544. PMID: 29756533.
      View in: PubMed
    2. Adkar SS, Brunger JM, Willard VP, Wu CL, Gersbach CA, Guilak F. Genome Engineering for Personalized Arthritis Therapeutics. Trends Mol Med. 2017 10; 23(10):917-931. PMID: 28887050.
      View in: PubMed
    3. Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F. Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports. 2017 05 09; 8(5):1202-1213. PMID: 28457885.
      View in: PubMed
    4. Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F. CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues. Arthritis Rheumatol. 2017 05; 69(5):1111-1121. PMID: 27813286.
      View in: PubMed
    5. Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD. * CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. Tissue Eng Part A. 2017 08; 23(15-16):738-749. PMID: 28095751.
      View in: PubMed
    6. Diekman BO, Thakore PI, O'Connor SK, Willard VP, Brunger JM, Christoforou N, Leong KW, Gersbach CA, Guilak F. Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells. Tissue Eng Part A. 2015 Apr; 21(7-8):1261-74. PMID: 25517798; PMCID: PMC4394871.
    7. Glass KA, Link JM, Brunger JM, Moutos FT, Gersbach CA, Guilak F. Tissue-engineered cartilage with inducible and tunable immunomodulatory properties. Biomaterials. 2014 Jul; 35(22):5921-31. PMID: 24767790; PMCID: PMC4047672.
    8. Brunger JM, Huynh NP, Guenther CM, Perez-Pinera P, Moutos FT, Sanchez-Adams J, Gersbach CA, Guilak F. Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. Proc Natl Acad Sci U S A. 2014 Mar 04; 111(9):E798-806. PMID: 24550481; PMCID: PMC3948308.
    9. Francisco AT, Mancino RJ, Bowles RD, Brunger JM, Tainter DM, Chen YT, Richardson WJ, Guilak F, Setton LA. Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. Biomaterials. 2013 Oct; 34(30):7381-8. PMID: 23849345; PMCID: PMC3771102.
    10. Perez-Pinera P, Ousterout DG, Brunger JM, Farin AM, Glass KA, Guilak F, Crawford GE, Hartemink AJ, Gersbach CA. Synergistic and tunable human gene activation by combinations of synthetic transcription factors. Nat Methods. 2013 Mar; 10(3):239-42. PMID: 23377379; PMCID: PMC3719416.
    11. Abrahamsson CK, Yang F, Park H, Brunger JM, Valonen PK, Langer R, Welter JF, Caplan AI, Guilak F, Freed LE. Chondrogenesis and mineralization during in vitro culture of human mesenchymal stem cells on three-dimensional woven scaffolds. Tissue Eng Part A. 2010 Dec; 16(12):3709-18. PMID: 20673022; PMCID: PMC2991213.