Joni Nikkanen, PhD

Title(s)Postdoctoral Scholar, Cellular Molecular Pharmacology
SchoolSchool of Medicine
Address1550 Fourth St
San Francisco CA 94158
Phone--
ORCID ORCID Icon0000-0001-7099-4061 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Helsinki, HelsinkiPhD12/2017Mitochondrial metabolism
    Helsinki University of Technology, HelsinkiM.Sc.05/2010Bioinformation technology

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    K99/R00 Pathway to Independence Award
    NIH NIDDK Apr 1, 2022 - Mar 31, 2027
    Long-Term Fellowship
    Human Frontier Science Program Organization Jan 1, 2019 - Jan 31, 2021
    Long-Term Fellowship
    EMBO Jan 1, 2018 - Dec 31, 2018

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes. J Cell Biol. 2023 Jan 02; 222(1). Ignatenko O, Malinen S, Rybas S, Vihinen H, Nikkanen J, Kononov A, Jokitalo ES, Ince-Dunn G, Suomalainen A. PMID: 36383135; PMCID: PMC9674092.
      View in: PubMed   Mentions:
    2. An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice. Science. 2022 10 21; 378(6617):290-295. Nikkanen J, Leong YA, Krause WC, Dermadi D, Maschek JA, Van Ry T, Cox JE, Weiss EJ, Gokcumen O, Chawla A, Ingraham HA. PMID: 36264814.
      View in: PubMed   Mentions:
    3. Mitochondrial spongiotic brain disease: astrocytic stress and harmful rapamycin and ketosis effect. Life Sci Alliance. 2020 09; 3(9). Ignatenko O, Nikkanen J, Kononov A, Zamboni N, Ince-Dunn G, Suomalainen A. PMID: 32737078; PMCID: PMC7409372.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    4. Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions. Cell Metab. 2019 12 03; 30(6):1040-1054.e7. Forsström S, Jackson CB, Carroll CJ, Kuronen M, Pirinen E, Pradhan S, Marmyleva A, Auranen M, Kleine IM, Khan NA, Roivainen A, Marjamäki P, Liljenbäck H, Wang L, Battersby BJ, Richter U, Velagapudi V, Nikkanen J, Euro L, Suomalainen A. PMID: 31523008.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    5. Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance. Cell. 2019 04 04; 177(2):399-413.e12. Ganeshan K, Nikkanen J, Man K, Leong YA, Sogawa Y, Maschek JA, Van Ry T, Chagwedera DN, Cox JE, Chawla A. PMID: 30853215; PMCID: PMC6456449.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    6. Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers. EMBO Mol Med. 2018 12; 10(12). Buzkova J, Nikkanen J, Ahola S, Hakonen AH, Sevastianova K, Hovinen T, Yki-Järvinen H, Pietiläinen KH, Lönnqvist T, Velagapudi V, Carroll CJ, Suomalainen A. PMID: 30373890; PMCID: PMC6284386.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    7. A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions. EMBO Mol Med. 2018 01; 10(1):13-21. Nikkanen J, Landoni JC, Balboa D, Haugas M, Partanen J, Paetau A, Isohanni P, Brilhante V, Suomalainen A. PMID: 29109127; PMCID: PMC5760859.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    8. mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression. Cell Metab. 2017 Aug 01; 26(2):419-428.e5. Khan NA, Nikkanen J, Yatsuga S, Jackson C, Wang L, Pradhan S, Kivelä R, Pessia A, Velagapudi V, Suomalainen A. PMID: 28768179.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    9. Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism. Cell Metab. 2016 Apr 12; 23(4):635-48. Nikkanen J, Forsström S, Euro L, Paetau I, Kohnz RA, Wang L, Chilov D, Viinamäki J, Roivainen A, Marjamäki P, Liljenbäck H, Ahola S, Buzkova J, Terzioglu M, Khan NA, Pirnes-Karhu S, Paetau A, Lönnqvist T, Sajantila A, Isohanni P, Tyynismaa H, Nomura DK, Battersby BJ, Velagapudi V, Carroll CJ, Suomalainen A. PMID: 26924217.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
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