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Mechanisms and efficacy of small molecule "latency promoting agents" to inhibit HIV reactivation ex vivo. JCI Insight. 2024 Aug 20.
Janssens J, Kim P, Kim SJ, Wedrychowski A, Kadiyala GN, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 39163135.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Differential susceptibility of cells infected with defective and intact HIV proviruses to killing by obatoclax and other small molecules. AIDS. 2024 07 15; 38(9):1281-1291.
Kadiyala GN, Telwatte S, Wedrychowski A, Janssens J, Kim SJ, Kim P, Deeks S, Wong JK, Yukl SA. PMID: 38626436; PMCID: PMC11216394.
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Translation:
HumansCells
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Saliva as a Testing Specimen with or without Pooling for SARS-CoV-2 Detection by Multiplex RT-PCR Test. Advances in Medical Imaging, Detection, and Diagnosis. 2023 Sep 6; 233-250.
Sun SQ, Li LJ, Ren RH, Pastor PL, Loginova LY, Madej MR, Taylor TK, Wong WJ, Zhang ZZ, Zhang ZA, Lu LC, Sha SM. .
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Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control. J Virol. 2023 01 31; 97(1):e0125422.
Wedrychowski A, Martin HA, Li Y, Telwatte S, Kadiyala GN, Melberg M, Etemad B, Connick E, Jacobson JM, Margolis DM, Skiest D, Volberding P, Hecht F, Deeks S, Wong JK, Li JZ, Yukl SA. PMID: 36541802; PMCID: PMC9888280.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Incidence of Severe COVID-19 Illness Following Vaccination and Booster With BNT162b2, mRNA-1273, and Ad26.COV2.S Vaccines. JAMA. 2022 10 11; 328(14):1427-1437.
Kelly JD, Leonard S, Hoggatt KJ, Boscardin WJ, Lum EN, Moss-Vazquez TA, Andino R, Wong JK, Byers A, Bravata DM, Tien PC, Keyhani S. PMID: 36156706; PMCID: PMC9513709.
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PubMed Mentions:
23 Fields:
Translation:
HumansCellsPHPublic Health
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ABX464 Decreases the Total Human Immunodeficiency Virus (HIV) Reservoir and HIV Transcription Initiation in CD4+ T Cells From Antiretroviral Therapy-Suppressed Individuals Living With HIV. Clin Infect Dis. 2022 06 10; 74(11):2044-2049.
Moron-Lopez S, Bernal S, Wong JK, Martinez-Picado J, Yukl SA. PMID: 34436569; PMCID: PMC9187309.
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PubMed Mentions:
8 Fields:
Translation:
HumansCellsCTClinical Trials
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Novel assays to investigate the mechanisms of latent infection with HIV-2. PLoS One. 2022; 17(4):e0267402.
Lu MD, Telwatte S, Kumar N, Ferreira F, Martin HA, Kadiyala GN, Wedrychowski A, Moron-Lopez S, Chen TH, Goecker EA, Coombs RW, Lu CM, Wong JK, Tsibris A, Yukl SA. PMID: 35476802; PMCID: PMC9045618.
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Translation:
HumansCells
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Gag p24 Is a Marker of Human Immunodeficiency Virus Expression in Tissues and Correlates With Immune Response. J Infect Dis. 2021 11 16; 224(9):1593-1598.
Wu G, Zuck P, Goh SL, Milush JM, Vohra P, Wong JK, Somsouk M, Yukl SA, Shacklett BL, Chomont N, Haase AT, Hatano H, Schacker TW, Deeks SG, Hazuda DJ, Hunt PW, Howell BJ. PMID: 33693750; PMCID: PMC8599810.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Tissue-specific differences in HIV DNA levels and mechanisms that govern HIV transcription in blood, gut, genital tract and liver in ART-treated women. J Int AIDS Soc. 2021 07; 24(7):e25738.
Moron-Lopez S, Xie G, Kim P, Siegel DA, Lee S, Wong JK, Price JC, Elnachef N, Greenblatt RM, Tien PC, Roan NR, Yukl SA. PMID: 34235864; PMCID: PMC8264406.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Sudden Cardiac Death and Myocardial Fibrosis, Determined by Autopsy, in Persons with HIV. N Engl J Med. 2021 06 17; 384(24):2306-2316.
Tseng ZH, Moffatt E, Kim A, Vittinghoff E, Ursell P, Connolly A, Olgin JE, Wong JK, Hsue PY. PMID: 34133860; PMCID: PMC8415173.
View in:
PubMed Mentions:
29 Fields:
Translation:
Humans
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Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts. Methods. 2022 05; 201:15-25.
Telwatte S, Martin HA, Marczak R, Fozouni P, Vallejo-Gracia A, Kumar GR, Murray V, Lee S, Ott M, Wong JK, Yukl SA. PMID: 33882362; PMCID: PMC8105137.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Abstract P21: Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test. Clinical Cancer Research. 2021 Mar 15; 27(6_Supplement):p21-p21.
Sun SQ, Li LJ, Ren RH, Pastor PL, Loginova LY, Wong WJ, Zhang ZZ, Zhang ZA, Lu LC, Sha SM. .
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Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA. J Virol Methods. 2021 06; 292:114115.
Telwatte S, Kumar N, Vallejo-Gracia A, Kumar GR, Lu CM, Ott M, Wong JK, Yukl SA. PMID: 33667568; PMCID: PMC7923865.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test. PLoS One. 2021; 16(2):e0243183.
Sun Q, Li J, Ren H, Pastor L, Loginova Y, Madej R, Taylor K, Wong JK, Zhang Z, Zhang A, Lu CM, Sha MY. PMID: 33621263; PMCID: PMC7901781.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCellsPHPublic Health
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Novel RT-ddPCR Assays for determining the transcriptional profile of SARS-CoV-2. bioRxiv. 2021 Jan 12.
Telwatte S, Kumar N, Vallejo-Gracia A, Kumar GR, Lu CM, Ott M, Wong JK, Yukl SA. PMID: 33469579; PMCID: PMC7814816.
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PubMed Mentions:
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Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. PLoS Pathog. 2020 11; 16(11):e1009060.
Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. PMID: 33253324; PMCID: PMC7728277.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents. AIDS. 2020 11 15; 34(14):2013-2024.
Telwatte S, Kim P, Chen TH, Milush JM, Somsouk M, Deeks SG, Hunt PW, Wong JK, Yukl SA. PMID: 32910065; PMCID: PMC7990078.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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OP 7.6 Tissue-specific differences in the mechanisms that govern HIV latency in blood, liver, gut and genital tract in ART-suppressed women. Journal of virus eradication. 2019 Dec 1; 5:40.
Moron-Lopez MS, Xie XG, Kim KP, Wong WJ, Price PJ, Elnachef EN, Greenblatt GR, Tien TP, Roan RN, Yukl YS. .
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OP 8.3 Intensification of ART with ABX464 decreases the total HIV reservoir and HIV transcription initiation in CD4 T cells from HIV-infected ART-suppressed individuals. Journal of virus eradication. 2019 Dec 1; 5:49.
Moron-Lopez MS, Bernal BS, Steens SJ, Wong WJ, Martinez-Picado MJ, Yukl YS. .
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PP 1.3 Single cell analysis reveals molecular signatures of HIV latency in primary cell models. Journal of virus eradication. 2019 Dec 1; 5:4.
Telwatte TS, Montano MM, Resop RR, Battivelli BE, Morón-López MS, Verdin VE, Greene GW, Bosque BA, Wong WJ, Yukl YS. .
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Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. Retrovirology. 2019 11 11; 16(1):32.
Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. PMID: 31711503; PMCID: PMC6849327.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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10 Tissue-specific effects of latency-reversing agents on HIV transcriptional blocks in gut and blood. Journal of virus eradication. 2019 Jul 1; 5:8.
Telwatte TS, Kim KP, Chen CT, Milush MJ, Somsouk SM, Hunt HP, Deeks DS, Wong WJ, Yukl YS. .
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12 In-depth transcription profile comparison of multiple primary cell HIV latency models. Journal of virus eradication. 2019 Jul 1; 5:9.
Moron-Lopez MS, Sarabia SI, Battivelli BE, Montano MM, Telwatte TS, Bosque BA, Verdin VE, Greene GW, Wong WJ, Yukl YS. .
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Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate. JCI Insight. 2019 04 04; 4(7).
Jiang G, Maverakis E, Cheng MY, Elsheikh MM, Deleage C, Méndez-Lagares G, Shimoda M, Yukl SA, Hartigan-O'Connor DJ, Thompson GR, Estes JD, Wong JK, Dandekar S. PMID: 30944245; PMCID: PMC6483647.
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PubMed Mentions:
12 Fields:
Translation:
HumansCellsCTClinical Trials
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Characterization of the HIV-1 transcription profile after romidepsin administration in ART-suppressed individuals. AIDS. 2019 03 01; 33(3):425-431.
Moron-Lopez S, Kim P, Søgaard OS, Tolstrup M, Wong JK, Yukl SA. PMID: 30531314; PMCID: PMC6374101.
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PubMed Mentions:
20 Fields:
Translation:
HumansCellsCTClinical Trials
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HIV POST SCD: RATES OF AUTOPSY-DEFINED SUDDEN ARRHYTHMIC DEATH AND CARDIAC FIBROSIS ARE >60% HIGHER IN PERSONS WITH HIV. Journal of the American College of Cardiology. 2019 Mar 1; 73(9):309.
Tseng TZ, Moffatt ME, Bedigian BA, Wong WJ, Vittinghoff VE, Connolly CA, Olgin OJ, Hsue HP. .
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Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency. PLoS Pathog. 2018 11; 14(11):e1007357.
Telwatte S, Lee S, Somsouk M, Hatano H, Baker C, Kaiser P, Kim P, Chen TH, Milush J, Hunt PW, Deeks SG, Wong JK, Yukl SA. PMID: 30440043; PMCID: PMC6237391.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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HIV latency in isolated patient CD4+ T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing. Sci Transl Med. 2018 02 28; 10(430).
Yukl SA, Kaiser P, Kim P, Telwatte S, Joshi SK, Vu M, Lampiris H, Wong JK. PMID: 29491188; PMCID: PMC5959841.
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PubMed Mentions:
175 Fields:
Translation:
HumansCells
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HIV latency is reversed by ACSS2-driven histone crotonylation. J Clin Invest. 2018 03 01; 128(3):1190-1198.
Jiang G, Nguyen D, Archin NM, Yukl SA, Méndez-Lagares G, Tang Y, Elsheikh MM, Thompson GR, Hartigan-O'Connor DJ, Margolis DM, Wong JK, Dandekar S. PMID: 29457784; PMCID: PMC5824862.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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Acetylation. . 2018 Jan 1; 1-6.
Cereseto CA, Wu WY, Davidson-Moncada DJ, Uldrick UT, Palefsky PJ, Yukl YS, Wong WJ, Makvandi-Nejad MS, Fletcher FC, Podany PA, Calcagno CA, William Wester WC, Brun-Vezinet BF, Matheron MS, Descamps DD, Toussi TS, Rosenberg RM, Singh SH, Glesby GM, Muiruri MC, Omar OH, Bartlett BJ, Libre LC, Batisse BJ, Guerrero GS, Marquet MR, Paillart PJ, Spear SM, Wu WY, Karsten KC, Pöhlmann PS, Papin PL, Daussy DC, Alfaisal AJ, Espert EL, Blanchet BF, Blanco BJ, Biard-Piechaczyk BM. .
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Anatomic Compartments as a Barrier to HIV Cure. Encyclopedia of AIDS. 2018 Jan 1; 32-55.
Yukl YS, Wong WJ. .
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Publisher Site Mentions:
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OP4.6 Gut and blood differ in mechanisms governing HIV transcription/latency. Journal of virus eradication. 2017 Dec 1; 3:22.
Telwatte TS, Lee LS, Somsouk SM, Hatano HH, Baker BC, Kim KP, Chen CT, Milush MJ, Hunt HP, Deeks DS, Wong WJ, Yukl YS. .
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Relative efficacy of T cell stimuli as inducers of productive HIV-1 replication in latently infected CD4 lymphocytes from patients on suppressive cART. Virology. 2017 08; 508:127-133.
Beliakova-Bethell N, Hezareh M, Wong JK, Strain MC, Lewinski MK, Richman DD, Spina CA. PMID: 28527342; PMCID: PMC5654527.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Impact of Allogeneic Hematopoietic Stem Cell Transplantation on the HIV Reservoir and Immune Response in 3 HIV-Infected Individuals. J Acquir Immune Defic Syndr. 2017 07 01; 75(3):328-337.
Koelsch KK, Rasmussen TA, Hey-Nguyen WJ, Pearson C, Xu Y, Bailey M, Marks KH, Sasson SC, Taylor MS, Tantau R, Obeid S, Milner B, Morrissey O, Pinto AN, Suzuki K, Busch MP, Keating SM, Kaiser P, Yukl S, Wong JK, Hiener BM, Palmer S, Zaunders J, Post JJ, Chan DJ, Avery S, Milliken ST, Kelleher AD, Lewin SR, Cooper DA. PMID: 28350553; PMCID: PMC6097982.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection. mBio. 2017 05 02; 8(3).
Jiang G, Santos Rocha C, Hirao LA, Mendes EA, Tang Y, Thompson GR, Wong JK, Dandekar S. PMID: 28465428; PMCID: PMC5414007.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Assays for precise quantification of total (including short) and elongated HIV-1 transcripts. J Virol Methods. 2017 04; 242:1-8.
Kaiser P, Joshi SK, Kim P, Li P, Liu H, Rice AP, Wong JK, Yukl SA. PMID: 28034670; PMCID: PMC5560404.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Tissue reservoirs of HIV. Curr Opin HIV AIDS. 2016 07; 11(4):362-70.
Wong JK, Yukl SA. PMID: 27259045; PMCID: PMC4928570.
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PubMed Mentions:
120 Fields:
Translation:
HumansCells
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Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation. Nat Med. 2016 07; 22(7):807-11.
Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK. PMID: 27294875; PMCID: PMC5004598.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansCells
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Long-term efavirenz use is associated with worse neurocognitive functioning in HIV-infected patients. J Neurovirol. 2016 Apr; 22(2):170-8.
Ma Q, Vaida F, Wong J, Sanders CA, Kao YT, Croteau D, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur JC, Morgello S, Simpson DM, Heaton RK, Grant I, Letendre SL, CHARTER Group. PMID: 26407716; PMCID: PMC4783211.
View in:
PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation. PLoS Pathog. 2015 Jul; 11(7):e1005066.
Jiang G, Mendes EA, Kaiser P, Wong DP, Tang Y, Cai I, Fenton A, Melcher GP, Hildreth JE, Thompson GR, Wong JK, Dandekar S. PMID: 26225771; PMCID: PMC4520526.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansCells
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Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults. PLoS One. 2015; 10(3):e0121290.
Yukl SA, Shergill AK, Girling V, Li Q, Killian M, Epling L, Li P, Kaiser P, Haase A, Havlir DV, McQuaid K, Sinclair E, Wong JK. PMID: 25811360; PMCID: PMC4374729.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids. Beilstein J Org Chem. 2015; 11:37-41.
Yu M, Wong JK, Tang C, Turner P, Todd MH, Rutledge PJ. PMID: 25670990; PMCID: PMC4311716.
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PubMed Mentions:
9
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Anatomic Compartments as a Barrier to HIV Cure. Encyclopedia of AIDS. 2015 Jan 1; 1-29.
Yukl YS, Wong WJ. .
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The Montreal Cognitive Assessment: A Pilot Study of a Brief Screening Tool for Mild and Moderate Cognitive Impairment in HIV-Positive Veterans. J Int Assoc Provid AIDS Care. 2015 May-Jun; 14(3):197-201.
Chartier M, Crouch PC, Tullis V, Catella S, Frawley E, Filanosky C, Carmody T, McQuaid J, Lampiris H, Wong JK. PMID: 25487428.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivo. PLoS One. 2014; 9(10):e109220.
Abdel-Mohsen M, Deng X, Danesh A, Liegler T, Jacobs ES, Rauch A, Ledergerber B, Norris PJ, Günthard HF, Wong JK, Pillai SK. PMID: 25275557; PMCID: PMC4183579.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ-NF-κB signaling. AIDS. 2014 Jul 17; 28(11):1555-66.
Jiang G, Mendes EA, Kaiser P, Sankaran-Walters S, Tang Y, Weber MG, Melcher GP, Thompson GR, Tanuri A, Pianowski LF, Wong JK, Dandekar S. PMID: 24804860; PMCID: PMC4922310.
View in:
PubMed Mentions:
59 Fields:
Translation:
HumansCells
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Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells. Immunol Cell Biol. 2014 Oct; 92(9):770-80.
Li P, Fujimoto K, Bourguingnon L, Yukl S, Deeks S, Wong JK. PMID: 24957217; PMCID: PMC4205896.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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HIV-1 drug resistance in the iPrEx preexposure prophylaxis trial. J Infect Dis. 2014 Oct 15; 210(8):1217-27.
Liegler T, Abdel-Mohsen M, Bentley LG, Atchison R, Schmidt T, Javier J, Mehrotra M, Eden C, Glidden DV, McMahan V, Anderson PL, Li P, Wong JK, Buchbinder S, Guanira JV, Grant RM, iPrEx Study Team. PMID: 24740633; PMCID: PMC4176446.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Advantages of using the QIAshredder instead of restriction digestion to prepare DNA for droplet digital PCR. Biotechniques. 2014; 56(4):194-6.
Yukl SA, Kaiser P, Kim P, Li P, Wong JK. PMID: 24724845; PMCID: PMC4948299.
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PubMed Mentions:
14 Fields:
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Discordance between peripheral and colonic markers of inflammation during suppressive ART. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):133-41.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. PMID: 24121758; PMCID: PMC3997573.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
A comparison of methods for measuring rectal HIV levels suggests that HIV DNA resides in cells other than CD4+ T cells, including myeloid cells. AIDS. 2014 Jan 28; 28(3):439-42.
Yukl SA, Sinclair E, Somsouk M, Hunt PW, Epling L, Killian M, Girling V, Li P, Havlir DV, Deeks SG, Wong JK, Hatano H. PMID: 24322272; PMCID: PMC4130176.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Effect of left ventricular dysfunction and viral load on risk of sudden cardiac death in patients with human immunodeficiency virus. Am J Cardiol. 2014 Apr 01; 113(7):1260-5.
Moyers BS, Secemsky EA, Vittinghoff E, Wong JK, Havlir DV, Hsue PY, Tseng ZH. PMID: 24521717; PMCID: PMC3959566.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Multiplexed target detection using DNA-binding dye chemistry in droplet digital PCR. Anal Chem. 2013 Dec 03; 85(23):11619-27.
McDermott GP, Do D, Litterst CM, Maar D, Hindson CM, Steenblock ER, Legler TC, Jouvenot Y, Marrs SH, Bemis A, Shah P, Wong J, Wang S, Sally D, Javier L, Dinio T, Han C, Brackbill TP, Hodges SP, Ling Y, Klitgord N, Carman GJ, Berman JR, Koehler RT, Hiddessen AL, Walse P, Bousse L, Tzonev S, Hefner E, Hindson BJ, Cauly TH, Hamby K, Patel VP, Regan JF, Wyatt PW, Karlin-Neumann GA, Stumbo DP, Lowe AJ. PMID: 24180464.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Effects of alpha interferon treatment on intrinsic anti-HIV-1 immunity in vivo. J Virol. 2014 Jan; 88(1):763-7.
Abdel-Mohsen M, Deng X, Liegler T, Guatelli JC, Salama MS, Ghanem Hel-D, Rauch A, Ledergerber B, Deeks SG, Günthard HF, Wong JK, Pillai SK. PMID: 24155399; PMCID: PMC3911728.
View in:
PubMed Mentions:
18 Fields:
Translation:
Cells
-
Expression profile of host restriction factors in HIV-1 elite controllers. Retrovirology. 2013 Oct 16; 10:106.
Abdel-Mohsen M, Raposo RA, Deng X, Li M, Liegler T, Sinclair E, Salama MS, Ghanem Hel-D, Hoh R, Wong JK, David M, Nixon DF, Deeks SG, Pillai SK. PMID: 24131498; PMCID: PMC3827935.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog. 2013; 9(10):e1003691.
Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. PMID: 24130489; PMCID: PMC3795031.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCellsCTClinical Trials
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Comparison of HIV DNA and RNA in gut-associated lymphoid tissue of HIV-infected controllers and noncontrollers. AIDS. 2013 Sep 10; 27(14):2255-60.
Hatano H, Somsouk M, Sinclair E, Harvill K, Gilman L, Cohen M, Hoh R, Hunt PW, Martin JN, Wong JK, Deeks SG, Yukl SA. PMID: 24157906; PMCID: PMC4143147.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCells
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The distribution of HIV DNA and RNA in cell subsets differs in gut and blood of HIV-positive patients on ART: implications for viral persistence. J Infect Dis. 2013 Oct 15; 208(8):1212-20.
Yukl SA, Shergill AK, Ho T, Killian M, Girling V, Epling L, Li P, Wong LK, Crouch P, Deeks SG, Havlir DV, McQuaid K, Sinclair E, Wong JK. PMID: 23852128; PMCID: PMC3778964.
View in:
PubMed Mentions:
115 Fields:
Translation:
HumansCells
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Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 2013; 9(5):e1003347.
Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. PMID: 23671416; PMCID: PMC3649997.
View in:
PubMed Mentions:
154 Fields:
Translation:
HumansCellsCTClinical Trials
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PROLONGED QT INTERVAL PREDICTS SUDDEN CARDIAC DEATH IN HIV-INFECTED INDIVIDUALS. Journal of the American College of Cardiology. 2013 Mar 1; 61(10):e295.
Moyers MB, McGuire ML, Colburn CB, Havlir HD, Wong WJ, Hsue HP, Tseng TZ. .
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Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. PLoS Pathog. 2013 Feb; 9(2):e1003174.
Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'Doherty U, Palmer S, Deeks SG, Siliciano JD. PMID: 23459007; PMCID: PMC3573107.
View in:
PubMed Mentions:
367 Fields:
Translation:
HumansCells
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Assessment of population-based HIV RNA levels in a rural east African setting using a fingerprick-based blood collection method. Clin Infect Dis. 2013 Feb; 56(4):598-605.
Jain V, Liegler T, Kabami J, Chamie G, Clark TD, Black D, Geng EH, Kwarisiima D, Wong JK, Abdel-Mohsen M, Sonawane N, Aweeka FT, Thirumurthy H, Petersen ML, Charlebois ED, Kamya MR, Havlir DV, SEARCH Collaboration. PMID: 23243180; PMCID: PMC3552523.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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Higher HIV-1 genetic diversity is associated with AIDS and neuropsychological impairment. Virology. 2012 Nov 25; 433(2):498-505.
Hightower GK, Wong JK, Letendre SL, Umlauf AA, Ellis RJ, Ignacio CC, Heaton RK, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Grant I, Little SJ, Richman DD, Kosakovsky Pond SL, Smith DM, CHARTER Study Group. PMID: 22999095; PMCID: PMC3466337.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Sudden cardiac death in patients with human immunodeficiency virus infection. J Am Coll Cardiol. 2012 May 22; 59(21):1891-6.
Tseng ZH, Secemsky EA, Dowdy D, Vittinghoff E, Moyers B, Wong JK, Havlir DV, Hsue PY. PMID: 22595409; PMCID: PMC3356565.
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PubMed Mentions:
138 Fields:
Translation:
Humans
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Genetic features of cerebrospinal fluid-derived subtype B HIV-1 tat. J Neurovirol. 2012 Apr; 18(2):81-90.
Choi JY, Hightower GK, Wong JK, Heaton R, Woods S, Grant I, Marcotte TD, Ellis RJ, Letendre SL, Collier AC, Marra CM, Clifford DB, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Richman DD, Smith DM, Charter Group. PMID: 22528397; PMCID: PMC3572198.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3035-40.
Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK, Swiss HIV Cohort Study. PMID: 22315404; PMCID: PMC3286922.
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PubMed Mentions:
84 Fields:
Translation:
HumansCells
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Neurocognitive and motor deficits in HIV-infected Ugandan children with high CD4 cell counts. Clin Infect Dis. 2012 Apr; 54(7):1001-9.
Ruel TD, Boivin MJ, Boal HE, Bangirana P, Charlebois E, Havlir DV, Rosenthal PJ, Dorsey G, Achan J, Akello C, Kamya MR, Wong JK. PMID: 22308272; PMCID: PMC3297647.
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PubMed Mentions:
85 Fields:
Translation:
Humans
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Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliter. J Virol Methods. 2011 Aug; 175(2):261-5.
Yukl SA, Li P, Fujimoto K, Lampiris H, Lu CM, Hare CB, Deeks SG, Liegler T, Pandori M, Havlir DV, Wong JK. PMID: 21536073; PMCID: PMC3827908.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy. J Virol. 2011 May; 85(10):4772-82.
Lerner P, Guadalupe M, Donovan R, Hung J, Flamm J, Prindiville T, Sankaran-Walters S, Syvanen M, Wong JK, George MD, Dandekar S. PMID: 21345945; PMCID: PMC3126205.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Early virologic failure and the development of antiretroviral drug resistance mutations in HIV-infected Ugandan children. J Acquir Immune Defic Syndr. 2011 Jan 01; 56(1):44-50.
Ruel TD, Kamya MR, Li P, Pasutti W, Charlebois ED, Liegler T, Dorsey G, Rosenthal PJ, Havlir DV, Wong JK, Achan J. PMID: 21099693; PMCID: PMC3078046.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol. 2011 Feb; 17(1):3-16.
Heaton RK, Franklin DR, Ellis RJ, McCutchan JA, Letendre SL, Leblanc S, Corkran SH, Duarte NA, Clifford DB, Woods SP, Collier AC, Marra CM, Morgello S, Mindt MR, Taylor MJ, Marcotte TD, Atkinson JH, Wolfson T, Gelman BB, McArthur JC, Simpson DM, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I, CHARTER Group, HNRC Group. PMID: 21174240; PMCID: PMC3032197.
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PubMed Mentions:
958 Fields:
Translation:
HumansCells
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HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study. Neurology. 2010 Dec 07; 75(23):2087-96.
Heaton RK, Clifford DB, Franklin DR, Woods SP, Ake C, Vaida F, Ellis RJ, Letendre SL, Marcotte TD, Atkinson JH, Rivera-Mindt M, Vigil OR, Taylor MJ, Collier AC, Marra CM, Gelman BB, McArthur JC, Morgello S, Simpson DM, McCutchan JA, Abramson I, Gamst A, Fennema-Notestine C, Jernigan TL, Wong J, Grant I, CHARTER Group. PMID: 21135382; PMCID: PMC2995535.
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PubMed Mentions:
1428 Fields:
Translation:
Humans
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CD4+ T cell reconstitution, T cell activation, and memory T cell subset composition in blood and gut of HIV-negative and ART-suppressed HIV-positive patients: implications for HIV persistence in the gut. Journal of the International AIDS Society. 2010 Dec 1; 13(Suppl 3):o1.
Yukl YS, Sinclair SE, Epling EL, Li LQ, Shergill SA, McQuaid MK, Duan DL, Hare HB, Lampiris LH, Haase HA, Havlir HD, Wong WJ. .
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Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapy. AIDS. 2010 Oct 23; 24(16):2451-60.
Yukl SA, Shergill AK, McQuaid K, Gianella S, Lampiris H, Hare CB, Pandori M, Sinclair E, Günthard HF, Fischer M, Wong JK, Havlir DV. PMID: 20827162; PMCID: PMC2997807.
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PubMed Mentions:
142 Fields:
Translation:
HumansCells
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Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy. J Infect Dis. 2010 Nov 15; 202(10):1553-61.
Yukl SA, Gianella S, Sinclair E, Epling L, Li Q, Duan L, Choi AL, Girling V, Ho T, Li P, Fujimoto K, Lampiris H, Hare CB, Pandori M, Haase AT, Günthard HF, Fischer M, Shergill AK, McQuaid K, Havlir DV, Wong JK. PMID: 20939732; PMCID: PMC2997806.
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PubMed Mentions:
179 Fields:
Translation:
HumansCellsCTClinical Trials
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Novel application of Locked Nucleic Acid chemistry for a Taqman assay for measuring diverse human immunodeficiency virus type 1 subtypes. J Virol Methods. 2010 Dec; 170(1-2):115-20.
Li P, Ruel T, Fujimoto K, Hatano H, Yukl S, Eller LA, Liegler T, Kamya M, Gassasira A, Dorsey G, Rosenthal PJ, Havlir DV, Wong JK. PMID: 20863855; PMCID: PMC3280821.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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HIV-subtype A is associated with poorer neuropsychological performance compared with subtype D in antiretroviral therapy-naive Ugandan children. AIDS. 2010 May 15; 24(8):1163-70.
Boivin MJ, Ruel TD, Boal HE, Bangirana P, Cao H, Eller LA, Charlebois E, Havlir DV, Kamya MR, Achan J, Akello C, Wong JK. PMID: 20425886; PMCID: PMC2880483.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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NeuroAIDS in Africa. J Neurovirol. 2010 May; 16(3):189-202.
Robertson K, Liner J, Hakim J, Sankalé JL, Grant I, Letendre S, Clifford D, Diop AG, Jaye A, Kanmogne G, Njamnshi A, Langford TD, Weyessa TG, Wood C, Banda M, Hosseinipour M, Sacktor N, Nakasuja N, Bangirana P, Paul R, Joska J, Wong J, Boivin M, Holding P, Kammerer B, Van Rie A, Ive P, Nath A, Lawler K, Adebamowo C, Royal W, Joseph J, NeuroAIDS in Africa Conference Participants. PMID: 20500018; PMCID: PMC3549534.
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PubMed Mentions:
29 Fields:
Translation:
Humans
-
In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells. PLoS Pathog. 2010 Jan 29; 6(1):e1000748.
Wong JK, Strain MC, Porrata R, Reay E, Sankaran-Walters S, Ignacio CC, Russell T, Pillai SK, Looney DJ, Dandekar S. PMID: 20126442; PMCID: PMC2813272.
View in:
PubMed Mentions:
85 Fields:
Translation:
AnimalsCells
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Association between specific HIV-1 Env traits and virologic control in vivo. Infect Genet Evol. 2010 Apr; 10(3):365-72.
Joos B, Rieder P, Fischer M, Kuster H, Rusert P, Trkola A, Pillai SK, Wong JK, Weber R, Günthard HF. PMID: 19524069; PMCID: PMC3918463.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Dynamics of T cell activation accompanying CD4 recovery in antiretroviral treated HIV-infected Ugandan children. Clin Immunol. 2009 Jun; 131(3):410-4.
Ruel T, Ssewanyana I, Achan J, Gasasira A, Kamya MR, Kekitiinwa A, Wong JK, Cao H, Havlir D, Charlebois ED. PMID: 19303366; PMCID: PMC3032795.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activity. Virology. 2009 Apr 25; 387(1):98-108.
Yukl S, Pillai S, Li P, Chang K, Pasutti W, Ahlgren C, Havlir D, Strain M, Günthard H, Richman D, Rice AP, Daar E, Little S, Wong JK. PMID: 19268337; PMCID: PMC4474533.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
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Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations. Virology. 2009 Mar 01; 385(1):204-8.
Smith DM, Zárate S, Shao H, Pillai SK, Letendre SL, Wong JK, Richman DD, Frost SD, Ellis RJ, HNRC Group. PMID: 19100592; PMCID: PMC2794037.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Unexpected low-level viremia among HIV-infected Ugandan adults with untreated active tuberculosis. J Acquir Immune Defic Syndr. 2008 Dec 01; 49(4):458-60.
Srikantiah P, Wong JK, Liegler T, Walusimbi M, Mayanja-Kizza H, Kayanja HK, Mugerwa RD, Charlebois ED, Boom WH, Whalen CC, Havlir DV. PMID: 19011423; PMCID: PMC4752197.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
HIV and antiretroviral therapy in the brain: neuronal injury and repair. BMC Proceedings. 2008 Dec 1; 2(Suppl 1):s13.
Ellis ER, Langford LD, Masliah ME, Grant GI, Heaton HR, Wong WJ, Smith SD, Letendre LS, McCutchan MA. .
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Publisher Site Mentions:
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HIV rebounds from latently infected cells, rather than from continuing low-level replication. Proc Natl Acad Sci U S A. 2008 Oct 28; 105(43):16725-30.
Joos B, Fischer M, Kuster H, Pillai SK, Wong JK, Böni J, Hirschel B, Weber R, Trkola A, Günthard HF, Swiss HIV Cohort Study. PMID: 18936487; PMCID: PMC2575487.
View in:
PubMed Mentions:
193 Fields:
Translation:
HumansCells
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Estimating selection pressures on HIV-1 using phylogenetic likelihood models. Stat Med. 2008 Oct 15; 27(23):4779-89.
Kosakovsky Pond SL, Poon AF, Zárate S, Smith DM, Little SJ, Pillai SK, Ellis RJ, Wong JK, Leigh Brown AJ, Richman DD, Frost SD. PMID: 18381707; PMCID: PMC2634745.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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HIV RNA suppression among HIV-infected Ugandan children with measles. J Acquir Immune Defic Syndr. 2008 Jun 01; 48(2):225-7.
Ruel TD, Achan J, Gasasira AF, Charlebois ED, Mehbratu T, Rosenthal PJ, Dorsey G, Kamya MR, Kekitiinwa A, Wong J, Havlir DV. PMID: 18520684; PMCID: PMC3040680.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Persistence of transmitted drug resistance among subjects with primary human immunodeficiency virus infection. J Virol. 2008 Jun; 82(11):5510-8.
Little SJ, Frost SD, Wong JK, Smith DM, Pond SL, Ignacio CC, Parkin NT, Petropoulos CJ, Richman DD. PMID: 18353964; PMCID: PMC2395184.
View in:
PubMed Mentions:
111 Fields:
Translation:
HumansCells
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Inferring HIV transmission dynamics from phylogenetic sequence relationships. PLoS Med. 2008 Mar 18; 5(3):e69.
Pilcher CD, Wong JK, Pillai SK. PMID: 18351799; PMCID: PMC2267810.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Turning up the volume on mutational pressure: is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3). Retrovirology. 2008 Mar 13; 5:26.
Pillai SK, Wong JK, Barbour JD. PMID: 18339206; PMCID: PMC2323022.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Blood and guts and HIV: preferential HIV persistence in GI mucosa. J Infect Dis. 2008 Mar 01; 197(5):640-2.
Yukl S, Wong JK. PMID: 18260765.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. J Infect Dis. 2008 Feb 01; 197(3):411-9.
Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, Spina CA, Richman DD, Wong JK. PMID: 18248304.
View in:
PubMed Mentions:
90 Fields:
Translation:
HumansCells
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Long-term persistence of transmitted HIV drug resistance in male genital tract secretions: implications for secondary transmission. J Infect Dis. 2007 Aug 01; 196(3):356-60.
Smith DM, Wong JK, Shao H, Hightower GK, Mai SH, Moreno JM, Ignacio CC, Frost SD, Richman DD, Little SJ. PMID: 17597449.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
-
Positive in vivo selection of the HIV-1 envelope protein gp120 occurs at surface-exposed regions. J Infect Dis. 2007 Jul 15; 196(2):313-20.
Joos B, Fischer M, Schweizer A, Kuster H, Böni J, Wong JK, Weber R, Trkola A, Günthard HF. PMID: 17570120.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Covering all the bases: targeting HIV-1 integrase. J Acquir Immune Defic Syndr. 2006 Dec 15; 43(5):507-8.
Wong JK, Lampiris H. PMID: 17133210.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Lack of neutralizing antibody response to HIV-1 predisposes to superinfection. Virology. 2006 Nov 10; 355(1):1-5.
Smith DM, Strain MC, Frost SD, Pillai SK, Wong JK, Wrin T, Liu Y, Petropolous CJ, Daar ES, Little SJ, Richman DD. PMID: 16962152.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
Genetic attributes of cerebrospinal fluid-derived HIV-1 env. Brain. 2006 Jul; 129(Pt 7):1872-83.
Pillai SK, Pond SL, Liu Y, Good BM, Strain MC, Ellis RJ, Letendre S, Smith DM, Günthard HF, Grant I, Marcotte TD, McCutchan JA, Richman DD, Wong JK. PMID: 16735456.
View in:
PubMed Mentions:
64 Fields:
Translation:
HumansCells
-
HIV drug resistance acquired through superinfection. AIDS. 2005 Aug 12; 19(12):1251-6.
Smith DM, Wong JK, Hightower GK, Ignacio CC, Koelsch KK, Petropoulos CJ, Richman DD, Little SJ. PMID: 16052079.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
-
Low human immunodeficiency virus envelope diversity correlates with low in vitro replication capacity and predicts spontaneous control of plasma viremia after treatment interruptions. J Virol. 2005 Jul; 79(14):9026-37.
Joos B, Trkola A, Fischer M, Kuster H, Rusert P, Leemann C, Böni J, Oxenius A, Price DA, Phillips RE, Wong JK, Hirschel B, Weber R, Günthard HF, Swiss HIV Cohort Study. PMID: 15994796; PMCID: PMC1168724.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Effect of treatment, during primary infection, on establishment and clearance of cellular reservoirs of HIV-1. J Infect Dis. 2005 May 01; 191(9):1410-8.
Strain MC, Little SJ, Daar ES, Havlir DV, Gunthard HF, Lam RY, Daly OA, Nguyen J, Ignacio CC, Spina CA, Richman DD, Wong JK. PMID: 15809898.
View in:
PubMed Mentions:
170 Fields:
Translation:
HumansCells
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Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine. J Infect Dis. 2005 Apr 01; 191(7):1164-8.
Havlir DV, Koelsch KK, Strain MC, Margot N, Lu B, Ignacio CC, Miller MD, Wong JK, Gilead 903 Study Team. PMID: 15747253.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Semen-specific genetic characteristics of human immunodeficiency virus type 1 env. J Virol. 2005 Feb; 79(3):1734-42.
Pillai SK, Good B, Pond SK, Wong JK, Strain MC, Richman DD, Smith DM. PMID: 15650198; PMCID: PMC544119.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol. 2005 Feb; 79(3):1772-88.
Strain MC, Letendre S, Pillai SK, Russell T, Ignacio CC, Günthard HF, Good B, Smith DM, Wolinsky SM, Furtado M, Marquie-Beck J, Durelle J, Grant I, Richman DD, Marcotte T, McCutchan JA, Ellis RJ, Wong JK. PMID: 15650202; PMCID: PMC544082.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
-
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansCells
-
The prostate as a reservoir for HIV-1. AIDS. 2004 Jul 23; 18(11):1600-2.
Smith DM, Kingery JD, Wong JK, Ignacio CC, Richman DD, Little SJ. PMID: 15238781.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Attenuated and nonproductive viral transcription in the lymphatic tissue of HIV-1-infected patients receiving potent antiretroviral therapy. J Infect Dis. 2004 Jan 15; 189(2):273-85.
Fischer M, Joos B, Wong JK, Ott P, Opravil M, Hirschel B, Weber R, Günthard HF, Swiss HIV Cohort Study. PMID: 14722893.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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HIV evolution and escape. Trans Am Clin Climatol Assoc. 2004; 115:289-303.
Richman DD, Little SJ, Smith DM, Wrin T, Petropoulos C, Wong JK. PMID: 17060974; PMCID: PMC2263778.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Chapter 34 HIV Drug Susceptibility Testing. AIDS and Other Manifestations of HIV Infection. 2004 Jan 1; (Science2431989):883-904.
Wong WJ, Smith SD, Richman RD. .
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Publisher Site Mentions:
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Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years. J Virol. 2003 Oct; 77(20):11212-9.
Havlir DV, Strain MC, Clerici M, Ignacio C, Trabattoni D, Ferrante P, Wong JK. PMID: 14512569; PMCID: PMC224988.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansCellsCTClinical Trials
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Clade B HIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus. AIDS. 2003 May 02; 17(7):F11-6.
Koelsch KK, Smith DM, Little SJ, Ignacio CC, Macaranas TR, Brown AJ, Petropoulos CJ, Richman DD, Wong JK. PMID: 12700477.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4819-24.
Strain MC, Günthard HF, Havlir DV, Ignacio CC, Smith DM, Leigh-Brown AJ, Macaranas TR, Lam RY, Daly OA, Fischer M, Opravil M, Levine H, Bacheler L, Spina CA, Richman DD, Wong JK. PMID: 12684537; PMCID: PMC153639.
View in:
PubMed Mentions:
120 Fields:
Translation:
HumansCells
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Spatiotemporal dynamics of HIV propagation. J Theor Biol. 2002 Sep 07; 218(1):85-96.
Strain MC, Richman DD, Wong JK, Levine H. PMID: 12297072.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
-
Residual cell-associated unspliced HIV-1 RNA in peripheral blood of patients on potent antiretroviral therapy represents intracellular transcripts. Antivir Ther. 2002 Jun; 7(2):91-103.
Fischer M, Wong JK, Russenberger D, Joos B, Opravil M, Hirschel B, Trkola A, Kuster H, Weber R, Günthard HF, Swiss HIV Cohort Study. PMID: 12212929.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Persistent HIV-1-specific cellular responses despite prolonged therapeutic viral suppression. AIDS. 2002 Jan 25; 16(2):161-70.
Appay V, Hansasuta P, Sutton J, Schrier RD, Wong JK, Furtado M, Havlir DV, Wolinsky SM, McMichael AJ, Richman DD, Rowland-Jones SL, Spina CA. PMID: 11807299.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Prevalence and predictive value of intermittent viremia with combination hiv therapy. JAMA. 2001 Jul 11; 286(2):171-9.
Havlir DV, Bassett R, Levitan D, Gilbert P, Tebas P, Collier AC, Hirsch MS, Ignacio C, Condra J, Günthard HF, Richman DD, Wong JK. PMID: 11448280.
View in:
PubMed Mentions:
104 Fields:
Translation:
HumansCells
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Evidence for positive selection driving the evolution of HIV-1 env under potent antiviral therapy. Virology. 2001 Jun 05; 284(2):250-8.
Frost SD, Günthard HF, Wong JK, Havlir D, Richman DD, Leigh Brown AJ. PMID: 11384224.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years. J Infect Dis. 2001 May 01; 183(9):1318-27.
Günthard HF, Havlir DV, Fiscus S, Zhang ZQ, Eron J, Mellors J, Gulick R, Frost SD, Brown AJ, Schleif W, Valentine F, Jonas L, Meibohm A, Ignacio CC, Isaacs R, Gamagami R, Emini E, Haase A, Richman DD, Wong JK. PMID: 11294662.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection. J Infect Dis. 2001 Feb 15; 183(4):555-62.
Schacker T, Little S, Connick E, Gebhard K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Schooley RT, Richman D, Corey L, Haase AT. PMID: 11170980.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites. J Virol. 2000 Nov; 74(22):10269-73.
Brown AJ, Precious HM, Whitcomb JM, Wong JK, Quigg M, Huang W, Daar ES, D'Aquila RT, Keiser PH, Connick E, Hellmann NS, Petropoulos CJ, Richman DD, Little SJ. PMID: 11044070; PMCID: PMC110900.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy. J Infect Dis. 2000 Feb; 181(2):522-31.
Günthard HF, Wong JK, Spina CA, Ignacio C, Kwok S, Christopherson C, Hwang J, Haubrich R, Havlir D, Richman DD. PMID: 10669335.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansCellsPHPublic Health
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Multiple sites in HIV-1 reverse transcriptase associated with virological response to combination therapy. AIDS. 2000 Jan 07; 14(1):31-6.
Precious HM, Günthard HF, Wong JK, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD, Leigh Brown AJ. PMID: 10714565.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCellsCTClinical Trials
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Rapid accumulation of human immunodeficiency virus (HIV) in lymphatic tissue reservoirs during acute and early HIV infection: implications for timing of antiretroviral therapy. J Infect Dis. 2000 Jan; 181(1):354-7.
Schacker T, Little S, Connick E, Gebhard-Mitchell K, Zhang ZQ, Krieger J, Pryor J, Havlir D, Wong JK, Richman D, Corey L, Haase AT. PMID: 10608788.
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55 Fields:
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Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy. J Virol. 1999 Nov; 73(11):9404-12.
Günthard HF, Frost SD, Leigh-Brown AJ, Ignacio CC, Kee K, Perelson AS, Spina CA, Havlir DV, Hezareh M, Looney DJ, Richman DD, Wong JK. PMID: 10516049; PMCID: PMC112975.
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62 Fields:
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Sequence clusters in human immunodeficiency virus type 1 reverse transcriptase are associated with subsequent virological response to antiretroviral therapy. J Infect Dis. 1999 Oct; 180(4):1043-9.
Brown AJ, Günthard HF, Wong JK, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD. PMID: 10479129.
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2 Fields:
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HumansCellsCTClinical Trials
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Higher Selection Pressure from Antiretroviral Drugs in Vivo Results in Increased Evolutionary Distance in HIV-1 pol, Volume 259, Number 1 (1999), pages 154–165. Virology. 1999 Sep 1; 261(2):367.
Günthard GH, Leigh-Brown LA, D’Aquila DR, Johnson JV, Kuritzkes KD, Richman RD, Wong WJ. .
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Higher selection pressure from antiretroviral drugs in vivo results in increased evolutionary distance in HIV-1 pol. Virology. 1999 Jun 20; 259(1):154-65.
Günthard HF, Leigh-Brown AJ, D'Aquila RT, Johnson VA, Kuritzkes DR, Richman DD, Wong JK, D'aquila RT. PMID: 10364500.
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11 Fields:
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Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9):5169-72.
Zhang ZQ, Schuler T, Cavert W, Notermans DW, Gebhard K, Henry K, Havlir DV, Günthard HF, Wong JK, Little S, Feinberg MB, Polis MA, Schrager LK, Schacker TW, Richman DD, Corey L, Danner SA, Haase AT. PMID: 10220437; PMCID: PMC21835.
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20 Fields:
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Comparative performance of high-density oligonucleotide sequencing and dideoxynucleotide sequencing of HIV type 1 pol from clinical samples. AIDS Res Hum Retroviruses. 1998 Jul 01; 14(10):869-76.
Günthard HF, Wong JK, Ignacio CC, Havlir DV, Richman DD. PMID: 9671215.
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50 Fields:
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Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy. J Virol. 1998 Mar; 72(3):2422-8.
Günthard HF, Wong JK, Ignacio CC, Guatelli JC, Riggs NL, Havlir DV, Richman DD. PMID: 9499103; PMCID: PMC109542.
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41 Fields:
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HumansCellsCTClinical Trials
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Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science. 1997 Nov 14; 278(5341):1291-5.
Wong JK, Hezareh M, Günthard HF, Havlir DV, Ignacio CC, Spina CA, Richman DD. PMID: 9360926.
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944 Fields:
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Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12574-9.
Wong JK, Günthard HF, Havlir DV, Zhang ZQ, Haase AT, Ignacio CC, Kwok S, Emini E, Richman DD. PMID: 9356491; PMCID: PMC25043.
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65 Fields:
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HumansCellsCTClinical Trials
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In vivo compartmentalization of human immunodeficiency virus: evidence from the examination of pol sequences from autopsy tissues. J Virol. 1997 Mar; 71(3):2059-71.
Wong JK, Ignacio CC, Torriani F, Havlir D, Fitch NJ, Richman DD. PMID: 9032338; PMCID: PMC191294.
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118 Fields:
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Streptococcus anginosus-constellatus infection of the sternoclavicular joint. J Rheumatol. 1984 Oct; 11(5):713-5.
Hynd RF, Klofkorn RW, Wong JK. PMID: 6392552.
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1 Fields:
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