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Joshua Pottel, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentPharmaceutical Chemistry
Address1700 4th Street
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Pottel J, Levit A, Korczynska M, Fischer M, Shoichet BK. The Recognition of Unrelated Ligands by Individual Proteins. ACS Chem Biol. 2018 Aug 10. PMID: 30095890.
      View in: PubMed
    2. Pottel J, Moitessier N. Customizable Generation of Synthetically Accessible, Local Chemical Subspaces. J Chem Inf Model. 2017 03 27; 57(3):454-467. PMID: 28234470.
      View in: PubMed
    3. Irwin JJ, Pottel J, Zou L, Wen H, Zuk S, Zhang X, Sterling T, Shoichet BK, Lionberger R, Giacomini KM. A Molecular Basis for Innovation in Drug Excipients. Clin Pharmacol Ther. 2017 Mar; 101(3):320-323. PMID: 27557422.
      View in: PubMed
    4. Moitessier N, Pottel J, Therrien E, Englebienne P, Liu Z, Tomberg A, Corbeil CR. Medicinal Chemistry Projects Requiring Imaginative Structure-Based Drug Design Methods. Acc Chem Res. 2016 Sep 20; 49(9):1646-57. PMID: 27529781.
      View in: PubMed
    5. Liu Z, Pottel J, Shahamat M, Tomberg A, Labute P, Moitessier N. Elucidating Hyperconjugation from Electronegativity to Predict Drug Conformational Energy in a High Throughput Manner. J Chem Inf Model. 2016 04 25; 56(4):788-801. PMID: 27028941.
      View in: PubMed
    6. Pottel J, Moitessier N. Single-Point Mutation with a Rotamer Library Toolkit: Toward Protein Engineering. J Chem Inf Model. 2015 Dec 28; 55(12):2657-71. PMID: 26623941.
      View in: PubMed
    7. Mendoza-Sanchez R, Cotnoir-White D, Kulpa J, Jutras I, Pottel J, Moitessier N, Mader S, Gleason JL. Design, synthesis and evaluation of antiestrogen and histone deacetylase inhibitor molecular hybrids. Bioorg Med Chem. 2015 Dec 15; 23(24):7597-606. PMID: 26613635.
      View in: PubMed
    8. Tomberg A, Pottel J, Liu Z, Labute P, Moitessier N. Understanding P450-mediated Bio-transformations into Epoxide and Phenolic Metabolites. Angew Chem Int Ed Engl. 2015 Nov 09; 54(46):13743-7. PMID: 26418278.
      View in: PubMed
    9. Schiavini P, Pottel J, Moitessier N, Auclair K. Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications. ChemMedChem. 2015 Jul; 10(7):1174-83. PMID: 26018317.
      View in: PubMed
    10. Pottel J, Therrien E, Gleason JL, Moitessier N. Docking ligands into flexible and solvated macromolecules. 6. Development and application to the docking of HDACs and other zinc metalloenzymes inhibitors. J Chem Inf Model. 2014 Jan 27; 54(1):254-65. PMID: 24364808.
      View in: PubMed
    11. Bezanson M, Pottel J, Bilbeisi R, Toumieux S, Cueto M, Moitessier N. Stereo- and regioselective synthesis of polysubstituted chiral 1,4-oxazepanes. J Org Chem. 2013 Feb 01; 78(3):872-85. PMID: 23305339.
      View in: PubMed
    12. Campagna-Slater V, Pottel J, Therrien E, Cantin LD, Moitessier N. Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by p450s. J Chem Inf Model. 2012 Sep 24; 52(9):2471-83. PMID: 22916680.
      View in: PubMed
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