Juan Irwin • UCSF Profiles

Juan Irwin, MD, PhD

Title(s)	Recall NFA, Ob/Gyn, Reproductive Sciences
School	School of Medicine
Address	513 Parnassus Ave, HSE San Francisco CA 94143
Phone	415-476-2039
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood. BMC Med. 2022 Apr 15; 20(1):158. Vallvé-Juanico J, George AF, Sen S, Thomas R, Shin MG, Kushnoor D, Vásquez JJ, Vo KC, Irwin JC, Roan NR, Combes AJ, Giudice LC. PMID: 35421980; PMCID: PMC9011995.

View in: PubMed Mentions:
Whole-Tissue Deconvolution and scRNAseq Analysis Identify Altered Endometrial Cellular Compositions and Functionality Associated With Endometriosis. Front Immunol. 2021; 12:788315. Bunis DG, Wang W, Vallvé-Juanico J, Houshdaran S, Sen S, Ben Soltane I, Kosti I, Vo KC, Irwin JC, Giudice LC, Sirota M. PMID: 35069565; PMCID: PMC8766492.

View in: PubMed Mentions:
Patterns of sex hormone receptor expression in stimulated endometrium from oocyte donors. Hum Fertil (Camb). 2021 Jan 19; 1-16. Manvelyan E, Houshdaran S, Irwin JC, Giudice LC, Aghajanova L. PMID: 33464141.

View in: PubMed Mentions: Fields:
Rep Reproductive Medicine
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. Int J Mol Sci. 2020 Apr 09; 21(7). Houshdaran S, Chen JC, Vallvé-Juanico J, Balayan S, Vo KC, Smith-McCune K, Greenblatt RM, Irwin JC, Giudice LC. PMID: 32283828; PMCID: PMC7177488.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Che Chemistry Mol Molecular Biology
Translation:Humans Cells
A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience. Biopreserv Biobank. 2020 Jun; 18(3):180-188. Sajo MEJV, Teves JMY, Corachea AJM, Diaz LA, Chan AFO, Valparaiso AP, Dy Echo AVV, Macalindong SS, Uy GLB, Dofitas RB, Habana MAE, Gerona RR, Irwin JC, Giudice LC, Velarde MC. PMID: 32202927.

View in: PubMed Mentions: Fields:
Bio Biotechnology
Translation:Humans
In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. J Assist Reprod Genet. 2018 May; 35(5):757-770. Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC. PMID: 29404863; PMCID: PMC5984879.

View in: PubMed Mentions: 16 Fields:
Gen Genetics Rep Reproductive Medicine
Translation:Humans Cells
Effects of noncavity-distorting fibroids on endometrial gene expression and function. Biol Reprod. 2017 Oct 01; 97(4):564-576. Aghajanova L, Houshdaran S, Irwin JC, Giudice LC. PMID: 29025102; PMCID: PMC6279121.

View in: PubMed Mentions: 3 Fields:
Rep Reproductive Medicine
Translation:Humans
Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium. Biol Reprod. 2017 Sep 01; 97(3):387-399. Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC. PMID: 29024986; PMCID: PMC5803759.

View in: PubMed Mentions: 2 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Estrogen and progesterone receptors show distinct patterns in differentendometrial cells of oocyte donors after ovarian stimulation. Fertility and Sterility. 2017 Sep 1; 108(3):e234. Manvelyan ME, Aghajanova AL, Houshdaran HS, Irwin IJ, Giudice GL. .

View in: Publisher Site Mentions:
Platelets for endometrial regeneration: a novel approach. Fertility and Sterility. 2016 Sep 1; 106(3):e82. Aghajanova AL, Houshdaran HS, Balayan BS, Irwin IJ, Huddleston HH, Giudice GL. .

View in: Publisher Site Mentions:
Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis. Biol Reprod. 2016 11; 95(5):93. Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC. PMID: 27535958; PMCID: PMC5178151.

View in: PubMed Mentions: 23 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. Biol Reprod. 2016 05; 94(5):118. Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC. PMID: 27075616; PMCID: PMC4939744.

View in: PubMed Mentions: 35 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril. 2016 Feb; 105(2):501-10.e1. Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC. PMID: 26515378; PMCID: PMC4744114.

View in: PubMed Mentions: 4 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Mid-secretory eutopic endometrium in intramural fibroids and severe endometriosis: relevance to fertility. Fertility and Sterility. 2015 Sep 1; 104(3):e344. Aghajanova AL, Irwin IJ, Giudice GL. .

View in: Publisher Site Mentions:
Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. PMID: 26177352; PMCID: PMC4503751.

View in: PubMed Mentions: 17 Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC. PMID: 25634912; PMCID: PMC4565478.

View in: PubMed Mentions: 19 Fields:
Rep Reproductive Medicine
Translation:Humans
Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract. AIDS Research and Human Retroviruses. 2014 Oct 1; 30(S1):a238-a238. Smith-McCune SK, Chen CJ, Greenblatt GR, Shacklett SB, Shanmugasundaram SU, Hilton HJ, Johnson JB, Barragan BF, Irwin IJ, Takeda TM, Pannell PJ, Perry PJ, Giudice GL. .

View in: Publisher Site Mentions:
Molecular classification of endometriosis and disease stage using high-dimensional genomic data. Endocrinology. 2014 Dec; 155(12):4986-99. Tamaresis JS, Irwin JC, Goldfien GA, Rabban JT, Burney RO, Nezhat C, DePaolo LV, Giudice LC. PMID: 25243856; PMCID: PMC4239429.

View in: PubMed Mentions: 38 Fields:
End Endocrinology
Translation:Humans Cells
Ovarian hormones induce differential DNA methylome in decidualizing versus non-decidualizing fibroblasts in patients with endometriosis. Fertility and Sterility. 2014 Sep 1; 102(3):e79. Houshdaran HS, Irwin IJ, Giudice GL. .

View in: Publisher Site Mentions:
Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation. Mol Endocrinol. 2014 Jul; 28(7):1118-35. Houshdaran S, Zelenko Z, Irwin JC, Giudice LC. PMID: 24877562; PMCID: PMC4075160.

View in: PubMed Mentions: 24 Fields:
End Endocrinology Mol Molecular Biology
Translation:Humans Cells
Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod. 2014 Jun; 29(6):1255-70. Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. PMID: 24626806; PMCID: PMC4017943.

View in: PubMed Mentions: 27 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Inhibition of epidermal growth factor receptor restores decidualization markers in stromal fibroblasts from women with endometriosis. Journal of Endometriosis and Pelvic Pain Disorders. 2014 Jan 1; 6(4):196-211. Erikson ED, Chen CJ, Piltonen PT, Conti CM, Irwin IJ, Giudice GL. .

View in: Publisher Site Mentions:
Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production. Fertil Steril. 2013 Oct; 100(4):1132-43. Chen JC, Erikson DW, Piltonen TT, Meyer MR, Barragan F, McIntire RH, Tamaresis JS, Vo KC, Giudice LC, Irwin JC. PMID: 23849844; PMCID: PMC3820417.

View in: PubMed Mentions: 18 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Human endometrial co-culture system reveals novel cell-specific effects of nonoxynol-9 on endometrial transcriptome and chemokine secretion. Fertility and Sterility. 2012 Sep 1; 98(3):s27. Chen CJ, Erikson ED, Barragan BF, Irwin IJ, Greene GW, Giudice GL. .

View in: Publisher Site Mentions:
Aberrant steroid hormone response and increased pro-inflammatory cytokine secretion in endometrial stromal fibroblasts from women with PCOS. Fertility and Sterility. 2012 Sep 1; 98(3):s26. Piltonen PT, Chen CJ, Spitzer ST, Irwin IJ, Giudice GL. .

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Pro-inflammatory effects of seminal plasma on human endometrium: implications for implantation and human immunodeficiency virus (HIV) transmission. Fertility and Sterility. 2012 Sep 1; 98(3):s221. Johnson JB, Chen CJ, Roan RN, Barragan BF, Irwin IJ, Giudice GL. .

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Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod. 2012 Feb; 86(2):58. Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice LC. PMID: 22075475; PMCID: PMC3290674.

View in: PubMed Mentions: 74 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation. Biol Reprod. 2012 Jan; 86(1):1-21. Aghajanova L, Shen S, Rojas AM, Fisher SJ, Irwin JC, Giudice LC. PMID: 21865555.

View in: PubMed Mentions: 21 Fields:
Rep Reproductive Medicine
Translation:Humans Cells
Effects of Nonoxynol-9 on Endometrial Cytokine Secretion Using an In Vitro Co-Culture System in HIV-Negative Women. Biology of Reproduction. 2011 Jul 1; 85(Suppl_1):41-41. Chen CJ, Irwin IJ, Meyer MM, McIntire MR, Zelenko ZZ, Tamaresis TJ, Vo VK, Giudice GL. .

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Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development. Fertil Steril. 2011 May; 95(6):2120-2, 2122.e1-12. Sheldon E, Vo KC, McIntire RA, Aghajanova L, Zelenko Z, Irwin JC, Giudice LC. PMID: 21371706; PMCID: PMC3080464.

View in: PubMed Mentions: 18 Fields:
Rep Reproductive Medicine
Translation:Humans