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Judd Hultquist, PhD

Title(s)Postdoctoral Scholar, Gladstone Institutes
SchoolSchool of Medicine
Address1700 4th Street
San Francisco CA 94158
Phone--
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    The Influence of Early Integration Events on HIV Latency and Reactivation Potential
    NIH/NIAID K22AI136691Jul 25, 2018 - Jun 30, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Unique Clade of SARS-CoV-2 Viruses is Associated with Lower Viral Loads in Patient Upper Airways. medRxiv. 2020 May 26. Lorenzo-Redondo R, Nam HH, Roberts SC, Simons LM, Jennings LJ, Qi C, Achenbach CJ, Hauser AR, Ison MG, Hultquist JF, Ozer EA. PMID: 32511558.
      View in: PubMed   Mentions:
    2. mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1. Nat Commun. 2020 May 15; 11(1):2449. Du Y, Hultquist JF, Zhou Q, Olson A, Tseng Y, Zhang TH, Hong M, Tang K, Chen L, Meng X, McGregor MJ, Dai L, Gong D, Martin-Sancho L, Chanda S, Li X, Bensenger S, Krogan NJ, Sun R. PMID: 32415096.
      View in: PubMed   Mentions:    Fields:    
    3. Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5a Binding to the Viral Core. Cell Rep. 2020 Mar 17; 30(11):3766-3777.e6. Selyutina A, Persaud M, Simons LM, Bulnes-Ramos A, Buffone C, Martinez-Lopez A, Scoca V, Di Nunzio F, Hiatt J, Marson A, Krogan NJ, Hultquist JF, Diaz-Griffero F. PMID: 32187548.
      View in: PubMed   Mentions:    Fields:    
    4. A systems approach to infectious disease. Nat Rev Genet. 2020 Jun; 21(6):339-354. Eckhardt M, Hultquist JF, Kaake RM, Hüttenhain R, Krogan NJ. PMID: 32060427.
      View in: PubMed   Mentions:    Fields:    
    5. Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells. Nat Biotechnol. 2019 09; 37(9):1034-1037. Leenay RT, Aghazadeh A, Hiatt J, Tse D, Roth TL, Apathy R, Shifrut E, Hultquist JF, Krogan N, Wu Z, Cirolia G, Canaj H, Leonetti MD, Marson A, May AP, Zou J. PMID: 31359007.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection. Cell Host Microbe. 2019 07 10; 26(1):86-99.e7. Hüttenhain R, Xu J, Burton LA, Gordon DE, Hultquist JF, Johnson JR, Satkamp L, Hiatt J, Rhee DY, Baek K, Crosby DC, Frankel AD, Marson A, Harper JW, Alpi AF, Schulman BA, Gross JD, Krogan NJ. PMID: 31253590.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. CRISPR-Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV-host factor interactions. Nat Protoc. 2019 01; 14(1):1-27. Hultquist JF, Hiatt J, Schumann K, McGregor MJ, Roth TL, Haas P, Doudna JA, Marson A, Krogan NJ. PMID: 30559373.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 2018 12 13; 175(7):1917-1930.e13. Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ. PMID: 30550789.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Influenza virus infection causes global RNAPII termination defects. Nat Struct Mol Biol. 2018 09; 25(9):885-893. Zhao N, Sebastiano V, Moshkina N, Mena N, Hultquist J, Jimenez-Morales D, Ma Y, Rialdi A, Albrecht R, Fenouil R, Sánchez-Aparicio MT, Ayllon J, Ravisankar S, Haddad B, Ho JSY, Low D, Jin J, Yurchenko V, Prinjha RK, Tarakhovsky A, Squatrito M, Pinto D, Allette K, Byun M, Smith ML, Sebra R, Guccione E, Tumpey T, Krogan N, Greenbaum B, van Bakel H, García-Sastre A, Marazzi I. PMID: 30177761.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. CRL4AMBRA1 targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling. EMBO J. 2018 09 14; 37(18). Chen SH, Jang GM, Hüttenhain R, Gordon DE, Du D, Newton BW, Johnson JR, Hiatt J, Hultquist JF, Johnson TL, Liu YL, Burton LA, Ye J, Reichermeier KM, Stroud RM, Marson A, Debnath J, Gross JD, Krogan NJ. PMID: 30166453.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses. Sci Rep. 2018 May 14; 8(1):7782. Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML. PMID: 29760472.
      View in: PubMed   Mentions:    Fields:    
    12. SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses. Sci Rep. 2018 02 01; 8(1):2092. Dornfeld D, Dudek AH, Vausselin T, Günther SC, Hultquist JF, Giese S, Khokhlova-Cubberley D, Chew YC, Pache L, Krogan NJ, Garcia-Sastre A, Schwemmle M, Shaw ML. PMID: 29391557.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors. PLoS Pathog. 2018 01; 14(1):e1006830. Binning JM, Smith AM, Hultquist JF, Craik CS, Caretta Cartozo N, Campbell MG, Burton L, La Greca F, McGregor MJ, Ta HM, Bartholomeeusen K, Peterlin BM, Krogan NJ, Sevillano N, Cheng Y, Gross JD. PMID: 29304101.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity. Cell. 2017 05 04; 169(4):679-692.e14. Rialdi A, Hultquist J, Jimenez-Morales D, Peralta Z, Campisi L, Fenouil R, Moshkina N, Wang ZZ, Laffleur B, Kaake RM, McGregor MJ, Haas K, Pefanis E, Albrecht RA, Pache L, Chanda S, Jen J, Ochando J, Byun M, Basu U, García-Sastre A, Krogan N, van Bakel H, Marazzi I. PMID: 28475896.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    15. Inhibition of CRISPR-Cas9 with Bacteriophage Proteins. Cell. 2017 Jan 12; 168(1-2):150-158.e10. Rauch BJ, Silvis MR, Hultquist JF, Waters CS, McGregor MJ, Krogan NJ, Bondy-Denomy J. PMID: 28041849.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    16. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nat Genet. 2017 Feb; 49(2):193-203. Park RJ, Wang T, Koundakjian D, Hultquist JF, Lamothe-Molina P, Monel B, Schumann K, Yu H, Krupzcak KM, Garcia-Beltran W, Piechocka-Trocha A, Krogan NJ, Marson A, Sabatini DM, Lander ES, Hacohen N, Walker BD. PMID: 27992415.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    17. A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells. Cell Rep. 2016 10 25; 17(5):1438-1452. Hultquist JF, Schumann K, Woo JM, Manganaro L, McGregor MJ, Doudna J, Simon V, Krogan NJ, Marson A. PMID: 27783955.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    18. Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. Immunity. 2016 Feb 1; 44(2):438. Nicholas S. Heaton, Natasha Moshkina, Romain Fenouil, Thomas J. Gardner, Sebastian Aguirre, Priya S. Shah, Nan Zhao, Lara Manganaro, Judd F. Hultquist, Justine Noel, David Sachs, Jennifer Hamilton, Paul E. Leon, Amit Chawdury, Shashank Tripathi, Camilla Melegari, Laura Campisi, Rong Hai, Giorgi Metreveli, Andrea V. Gamarnik, Adolfo García-Sastre, Benjamin Greenbaum, Viviana Simon, Ana Fernandez-Sesma, Nevan J. Krogan, Lubbertus C.F. Mulder, Harm van Bakel, Domenico Tortorella, Jack Taunton, Peter Palese, Ivan Marazzi. .
      View in: Publisher Site   Mentions:
    19. Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. Immunity. 2016 Jan 19; 44(1):46-58. Heaton NS, Moshkina N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist JF, Noel J, Sachs D, Hamilton J, Leon PE, Chawdury A, Tripathi S, Melegari C, Campisi L, Hai R, Metreveli G, Gamarnik AV, García-Sastre A, Greenbaum B, Simon V, Fernandez-Sesma A, Krogan NJ, Mulder LCF, van Bakel H, Tortorella D, Taunton J, Palese P, Marazzi I. PMID: 26789921.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    20. Lineage-Specific Viral Hijacking of Non-canonical E3 Ubiquitin Ligase Cofactors in the Evolution of Vif Anti-APOBEC3 Activity. Cell Rep. 2015 May 26; 11(8):1236-50. Kane JR, Stanley DJ, Hultquist JF, Johnson JR, Mietrach N, Binning JM, Jónsson SR, Barelier S, Newton BW, Johnson TL, Franks-Skiba KE, Li M, Brown WL, Gunnarsson HI, Adalbjornsdóttir A, Fraser JS, Harris RS, Andrésdóttir V, Gross JD, Krogan NJ. PMID: 25981045.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    21. Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity. PLoS Genet. 2014 Nov; 10(11):e1004761. Refsland EW, Hultquist JF, Luengas EM, Ikeda T, Shaban NM, Law EK, Brown WL, Reilly C, Emerman M, Harris RS. PMID: 25411794.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    22. APOBEC3F determinants of HIV-1 Vif sensitivity. J Virol. 2014 Nov; 88(21):12923-7. Land AM, Shaban NM, Evans L, Hultquist JF, Albin JS, Harris RS. PMID: 25142588.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    23. D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B. Virology. 2013 Jun 20; 441(1):31-9. McDougle RM, Hultquist JF, Stabell AC, Sawyer SL, Harris RS. PMID: 23542011.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    24. The restriction factors of human immunodeficiency virus. J Biol Chem. 2012 Nov 30; 287(49):40875-83. Harris RS, Hultquist JF, Evans DT. PMID: 23043100.
      View in: PubMed   Mentions: 122     Fields:    Translation:HumansAnimalsCells
    25. HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor ß on genetically distinct surfaces. AIDS Res Hum Retroviruses. 2012 Dec; 28(12):1543-51. Hultquist JF, McDougle RM, Anderson BD, Harris RS. PMID: 22725134.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    26. Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n. PLoS Pathog. 2012; 8(7):e1002800. Refsland EW, Hultquist JF, Harris RS. PMID: 22807680.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    27. APOBEC3B and AID have similar nuclear import mechanisms. J Mol Biol. 2012 Jun 22; 419(5):301-14. Lackey L, Demorest ZL, Land AM, Hultquist JF, Brown WL, Harris RS. PMID: 22446380.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    28. Vif proteins of human and simian immunodeficiency viruses require cellular CBFß to degrade APOBEC3 restriction factors. J Virol. 2012 Mar; 86(5):2874-7. Hultquist JF, Binka M, LaRue RS, Simon V, Harris RS. PMID: 22205746.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    29. Vif hijacks CBF-ß to degrade APOBEC3G and promote HIV-1 infection. Nature. 2011 Dec 21; 481(7381):371-5. Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ. PMID: 22190037.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansAnimalsCells
    30. Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. J Virol. 2011 Nov; 85(21):11220-34. Hultquist JF, Lengyel JA, Refsland EW, LaRue RS, Lackey L, Brown WL, Harris RS. PMID: 21835787.
      View in: PubMed   Mentions: 154     Fields:    Translation:HumansAnimalsCells
    31. Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function. J Virol. 2010 Oct; 84(19):10209-19. Albin JS, Haché G, Hultquist JF, Brown WL, Harris RS. PMID: 20686027.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    32. Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. Future Virol. 2009 Nov 01; 4(6):605. Hultquist JF, Harris RS. PMID: 20174454.
      View in: PubMed   Mentions:
    33. Feminized tassels of maize mop1 and ts1 mutants exhibit altered levels of miR156 and specific SBP-box genes. Planta. 2008 Dec; 229(1):99-113. Hultquist JF, Dorweiler JE. PMID: 18800226.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
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