Jue Lin, PhD

Title(s) Professional Research, Biochemistry and Biophysics
SchoolSchool of Medicine
Address600 16th St, #S316
San Francisco CA 94158
Phone415-476-7284
ORCID ORCID Icon0000-0001-7216-1610 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, San Francisco, CAPostdoctoral Studies07/2004Molecular and Cell Biology
    Cornell University, Ithaca, NYPh.D.05/1999Molecular and Cell Biology
    Fudan University, Shanghai, P.R. ChinaB.S.07/1992Biochemistry

    Collapse Research 
    Collapse Research Activities and Funding
    Optimization and standardization of telomere length measurement by qPCR for population-based health research
    NIH U01AG064785Sep 30, 2019 - May 31, 2022
    Role: Principal Investigator
    Inflammation, Aging, Microbes, Obstructive Lung Disease and Diffusion Abnormalities (I AM OLD-DA) Study
    NIH R01HL128156Jul 1, 2015 - Apr 30, 2025
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans: A Genome-Wide Association Study. JAMA Neurol. 2020 06 01; 77(6):746-754. Foo JN, Chew EGY, Chung SJ, Peng R, Blauwendraat C, Nalls MA, Mok KY, Satake W, Toda T, Chao Y, Tan LCS, Tandiono M, Lian MM, Ng EY, Prakash KM, Au WL, Meah WY, Mok SQ, Annuar AA, Chan AYY, Chen L, Chen Y, Jeon BS, Jiang L, Lim JL, Lin JJ, Liu C, Mao C, Mok V, Pei Z, Shang HF, Shi CH, Song K, Tan AH, Wu YR, Xu YM, Xu R, Yan Y, Yang J, Zhang B, Koh WP, Lim SY, Khor CC, Liu J, Tan EK. PMID: 32310270; PMCID: PMC7171584.
      View in: PubMed   Mentions: 93     Fields:    Translation:Humans
    2. Evaluating Mild Cognitive Dysfunction in Patients with Parkinson's Disease in Clinical Practice in Taiwan. Sci Rep. 2020 01 23; 10(1):1014. Yu RL, Lee WJ, Li JY, Chang YY, Chen CC, Lin JJ, Sung YF, Lin TK, Fuh JL. PMID: 31974411; PMCID: PMC6978523.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    3. Telomere length measurement by qPCR - Summary of critical factors and recommendations for assay design. Psychoneuroendocrinology. 2019 01; 99:271-278. Lin J, Smith DL, Esteves K, Drury S. PMID: 30343983; PMCID: PMC6363640.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    4. In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study. Psychoneuroendocrinology. 2018 10; 96:179-187. Lin J, Sun J, Wang S, Milush JM, Baker CAR, Coccia M, Effros RB, Puterman E, Blackburn E, Prather AA, Epel E. PMID: 29980010.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    5. Variability of presynaptic nigrostriatal dopaminergic function and clinical heterogeneity in a dopa-responsive dystonia family with GCH-1 gene mutation. J Neurol. 2018 Mar; 265(3):478-485. Lin JJ, Lu CS, Tsai CH. PMID: 29290055.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study. Neurobiol Aging. 2017 01; 49:217.e1-217.e4. Wang L, Heckman MG, Aasly JO, Annesi G, Bozi M, Chung SJ, Clarke C, Crosiers D, Eckstein G, Garraux G, Hadjigeorgiou GM, Hattori N, Jeon B, Kim YJ, Kubo M, Lesage S, Lin JJ, Lynch T, Lichtner P, Mellick GD, Mok V, Morrison KE, Quattrone A, Satake W, Silburn PA, Stefanis L, Stockton JD, Tan EK, Toda T, Brice A, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Gasser T, Krüger R, Farrer MJ, Ross OA, Sharma M, GEOPD Consortium. PMID: 27814993; PMCID: PMC5154911.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. PDD-5S: A useful screening tool for Parkinson's disease dementia. Parkinsonism Relat Disord. 2016 Apr; 25:85-90. Lee WJ, Wu SL, Li JY, Chen CC, Lin JJ, Peng GS, Lin TK, Wang SJ, Chen RS, Yang YH, Tsai CH, Hsu JL, Liao YC, Chen SP, Fuh JL. PMID: 26872691.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Large-scale assessment of polyglutamine repeat expansions in Parkinson disease. Neurology. 2015 Oct 13; 85(15):1283-92. Wang L, Aasly JO, Annesi G, Bardien S, Bozi M, Brice A, Carr J, Chung SJ, Clarke C, Crosiers D, Deutschländer A, Eckstein G, Farrer MJ, Goldwurm S, Garraux G, Hadjigeorgiou GM, Hicks AA, Hattori N, Klein C, Jeon B, Kim YJ, Lesage S, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pihlstrøm L, Pramstaller PP, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Silburn PA, Theuns J, Tan EK, Tomiyama H, Toft M, Van Broeckhoven C, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore DM, Krüger R, Sharma M, GEO-PD Consortium. PMID: 26354989; PMCID: PMC4617164.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    9. Prevalence and risk factors of cognitive impairment in Parkinson disease: a population-based case-control study in Taiwan. Medicine (Baltimore). 2015 May; 94(17):e782. Huang YC, Wu ST, Lin JJ, Lin CC, Kao CH. PMID: 25929923; PMCID: PMC4603038.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. TREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study. Parkinsonism Relat Disord. 2015 Mar; 21(3):306-9. Ortega-Cubero S, Lorenzo-Betancor O, Lorenzo E, Agúndez JA, Jiménez-Jiménez FJ, Ross OA, Wurster I, Mielke C, Lin JJ, Coria F, Clarimon J, Ezquerra M, Brighina L, Annesi G, Alonso-Navarro H, García-Martin E, Gironell A, Marti MJ, Yueh KC, Wszolek ZK, Sharma M, Berg D, Krüger R, Pastor MA, Pastor P. PMID: 25585992; PMCID: PMC4408541.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    11. Spinocerebellar ataxia 35: novel mutations in TGM6 with clinical and genetic characterization. Neurology. 2014 Oct 21; 83(17):1554-61. Guo YC, Lin JJ, Liao YC, Tsai PC, Lee YC, Soong BW. PMID: 25253745.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    12. Comparison of activities of daily living impairments in Parkinson's disease patients as defined by the Pill Questionnaire and assessments by neurologists. J Neurol Neurosurg Psychiatry. 2014 Sep; 85(9):969-73. Lee WJ, Chang YY, Lin JJ, Sung YF, Li JY, Wang SJ, Chen RS, Yang YH, Hu CJ, Tsai CH, Wang HC, Wu SL, Chang MH, Fuh JL. PMID: 24218526.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Reversible oro-lingual dyskinesia related to lithium intoxication. Acta Neurol Taiwan. 2013 Mar; 22(1):32-5. Chen WY, Chen AC, Tsai SJ, Lin JJ. PMID: 23479244.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. J Med Genet. 2012 Nov; 49(11):721-6. Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Bertram L, Bozi M, Barcikowska M, Crosiers D, Clarke CE, Facheris MF, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon BS, Jamrozik Z, Krygowska-Wajs A, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Libioulle C, Murata M, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Meitnger T, Zimprich A, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Strom TM, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Van Broeckhoven C, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yomono HS, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R, GEOPD consortium. PMID: 23125461; PMCID: PMC3488700.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    15. Familial paroxysmal nonkinesigenic dyskinesia: clinical and genetic analysis of a Taiwanese family. J Neurol Sci. 2012 Dec 15; 323(1-2):80-4. Yeh TH, Lin JJ, Lai SC, Wu-Chou YH, Chen AC, Yueh KC, Chen RS, Lu CS. PMID: 22967746.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14; 79(7):659-67. Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D, Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R, GEO-PD Consortium. PMID: 22786590; PMCID: PMC3414661.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    17. Telomeres and lifestyle factors: roles in cellular aging. Mutat Res. 2012 Feb 01; 730(1-2):85-9. Lin J, Epel E, Blackburn E. PMID: 21878343.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    18. Generalized chorea in the syndrome of acute bilateral basal ganglia lesions in patients with diabetic uremia. J Clin Neurosci. 2011 Sep; 18(9):1266-8. Lin JJ. PMID: 21752650.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan. N Engl J Med. 2011 Mar 24; 364(12):1126-33. Chen P, Lin JJ, Lu CS, Ong CT, Hsieh PF, Yang CC, Tai CT, Wu SL, Lu CH, Hsu YC, Yu HY, Ro LS, Lu CT, Chu CC, Tsai JJ, Su YH, Lan SH, Sung SF, Lin SY, Chuang HP, Huang LC, Chen YJ, Tsai PJ, Liao HT, Lin YH, Chen CH, Chung WH, Hung SI, Wu JY, Chang CF, Chen L, Chen YT, Shen CY, Taiwan SJS Consortium. PMID: 21428768.
      View in: PubMed   Mentions: 202     Fields:    Translation:Humans
    20. High frequency of multiexonic deletion of the GCH1 gene in a Taiwanese cohort of dopa-response dystonia. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 05; 153B(4):903-8. Wu-Chou YH, Yeh TH, Wang CY, Lin JJ, Huang CC, Chang HC, Lai SC, Chen RS, Weng YH, Huang CL, Lu CS. PMID: 20082337.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    21. A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiol Aging. 2011 Mar; 32(3):548.e9-18. Krüger R, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, Genetic Epidemiology of Parkinson's disease consortium. PMID: 20036034; PMCID: PMC4724437.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    22. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31; 352(1-2):71-80. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. PMID: 19837074; PMCID: PMC3280689.
      View in: PubMed   Mentions: 235     Fields:    Translation:HumansCells
    23. Safety/Tolerability and efficacy of rivastigmine in taiwanese patients with Alzheimer's disease: a prospective post-marketing surveillance study. Clin Drug Investig. 2009; 29(11):729-38. Chiu PY, Dai DE, Hsu HP, Lee C, Lin JJ, Kuo HC, Huang YC, Liu YC, Tsai CP. PMID: 19813776.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. 5,10-methylenetetrahydrofolate reductase C677T gene polymorphism can influence age at onset of Parkinson's disease. Acta Neurol Taiwan. 2007 Sep; 16(3):150-7. Lin JJ, Yueh KC, Liu CS, Liu JT, Lin SZ. PMID: 17966954.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Genetic polymorphism of the angiotensin converting enzyme and L-dopa-induced adverse effects in Parkinson's disease. J Neurol Sci. 2007 Jan 31; 252(2):130-4. Lin JJ, Yueh KC, Lin SZ, Harn HJ, Liu JT. PMID: 17196621.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    26. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet Genomics. 2006 Apr; 16(4):297-306. Hung SI, Chung WH, Jee SH, Chen WC, Chang YT, Lee WR, Hu SL, Wu MT, Chen GS, Wong TW, Hsiao PF, Chen WH, Shih HY, Fang WH, Wei CY, Lou YH, Huang YL, Lin JJ, Chen YT. PMID: 16538176.
      View in: PubMed   Mentions: 160     Fields:    Translation:Humans
    27. Homozygous deletion genotype of angiotensin converting enzyme confers protection against migraine in man. Acta Neurol Taiwan. 2005 Sep; 14(3):120-5. Lin JJ, Wang PJ, Chen CH, Yueh KC, Lin SZ, Harn HJ. PMID: 16252613.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. Lumbar zygapophyseal joint injections in patients with chronic lower back pain. J Chin Med Assoc. 2005 Feb; 68(2):59-64. Shih C, Lin GY, Yueh KC, Lin JJ. PMID: 15759816.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    29. Camptocormia in Parkinson's disease. Acta Neurol Taiwan. 2004 Mar; 13(1):46-7. Lin JJ. PMID: 15315302.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Improvement of generalised dystonia by olanzapine treatment. J Clin Neurosci. 2004 Jan; 11(1):84-6. Lin JJ, Chang DC. PMID: 14642376.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. The homozygote 10-copy genotype of variable number tandem repeat dopamine transporter gene may confer protection against Parkinson's disease for male, but not to female patients. J Neurol Sci. 2003 May 15; 209(1-2):87-92. Lin JJ, Yueh KC, Chang DC, Chang CY, Yeh YH, Lin SZ. PMID: 12686408.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    32. Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson's disease. J Neurol Sci. 2002 Jul 15; 199(1-2):25-9. Lin JJ, Yueh KC, Chang DC, Lin SZ. PMID: 12084438.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
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