-
Sphingosine phosphate lyase insufficiency syndrome as a primary immunodeficiency state. Adv Biol Regul. 2024 Oct 22; 94:101058.
Gharagozlou S, Wright NM, Murguila-Favela L, Eshleman J, Midgley J, Saygili S, Mathew G, Lesmana H, Makkoukdji N, Gans M, Saba JD. PMID: 39454238.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Factors influencing survival in sphingosine phosphate lyase insufficiency syndrome: a retrospective cross-sectional natural history study of 76 patients. Orphanet J Rare Dis. 2024 Sep 27; 19(1):355.
Keller N, Midgley J, Khalid E, Lesmana H, Mathew G, Mincham C, Teig N, Khan Z, Khosla I, Mehr S, Guran T, Buder K, Xu H, Alhasan K, Buyukyilmaz G, Weaver N, Saba JD. PMID: 39334450; PMCID: PMC11429486.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4 + cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype. bioRxiv. 2024 Sep 25.
Arcuschin CD, Kahrizi K, Sayaman RW, DiBenedetto C, Shen Y, Salaberry PJ, Zakroui O, Schwarzer C, Scapozza A, Betancur P, Saba JD, Coppé JP, Barcellos-Hoff MH, Kappes D, van 't Veer L, Schor IE, Muñoz DP. PMID: 39386673; PMCID: PMC11463473.
View in:
PubMed Mentions:
-
109 Chemical development of dual species–host and Aspergillus fumigatus–sphingosine-1-phosphate lyase inhibitors as therapeutic strategy in cystic fibrosis. Journal of Cystic Fibrosis. 2024 Sep 1; 23:s57-s58.
Costantini CC, Camaioni CE, Pampalone PG, Dindo DM, Pariano PM, Stincardini SC, Galarini GR, Paoletti PF, Ronchetti RR, Giovagnoli GS, Saba SJ, Romani RL, Cellini CB. .
View in:
Publisher Site Mentions:
-
Melanocortin-receptor 4 activation modulates proliferation and differentiation of rat postnatal hippocampal neural precursor cells. Neuropharmacology. 2024 Oct 01; 257:110058.
Carniglia L, Turati J, Saba J, López Couselo F, Romero AC, Caruso C, Durand D, Lasaga M. PMID: 38960135.
View in:
PubMed Mentions: Fields:
Translation:
AnimalsCells
-
The fate of intracellular S1P regulates lipid droplet turnover and lipotoxicity in pancreatic beta-cells. J Lipid Res. 2024 Aug; 65(8):100587.
Tang Y, Majewska M, Leß B, Mehmeti I, Wollnitzke P, Semleit N, Levkau B, Saba JD, van Echten-Deckert G, Gurgul-Convey E. PMID: 38950680; PMCID: PMC11345310.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
-
AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis. Oncogene. 2024 Apr; 43(16):1203-1213.
Oskouian B, Lee JY, Asgharzadeh S, Khan R, Zhang M, Weisbrod JR, Choi YJ, Puri L, Aguilar AE, Zhao P, Saba JD. PMID: 38413795; PMCID: PMC11014797.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Gene therapy with AAV9-SGPL1 in an animal model of lung fibrosis. J Pathol. 2024 05; 263(1):22-31.
Bhattacharyya A, Khan R, Lee JY, Tassew G, Oskouian B, Allende ML, Proia RL, Yin X, Ortega JG, Bhattacharya M, Saba JD. PMID: 38332723; PMCID: PMC10987276.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Prevalence estimate of sphingosine phosphate lyase insufficiency syndrome in worldwide and select populations. Genetics in Medicine Open. 2024 Jan 1; 2:100840.
Sedillo SJ, Badduke BC, Schrodi SS, Scaria SV, Onat OO, Alfadhel AM, Ober OC, Wentworth-Sheilds WW, Steiner SR, Saba SJ. .
View in:
Publisher Site Mentions:
-
AAV-SPL 2.0, a Modified Adeno-Associated Virus Gene Therapy Agent for the Treatment of Sphingosine Phosphate Lyase Insufficiency Syndrome. Int J Mol Sci. 2023 Oct 25; 24(21).
Khan R, Oskouian B, Lee JY, Hodgin JB, Yang Y, Tassew G, Saba JD. PMID: 37958544; PMCID: PMC10648410.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
148 Exploring dual targeting of host and microbial sphingosine-1-phosphate lyase as antimicrobial strategy in cystic fibrosis. Journal of Cystic Fibrosis. 2023 Oct 1; 22:s78-s79.
Costantini CC, Pampalone PG, Pariano PM, Zelante ZT, Macchioni ML, Galarini GR, Camaioni CE, Paoletti PF, Catalano CF, Davidescu DM, Stincardini SC, Bellet BM, Saba SJ, Giardina GG, Giovagnoli GS, Cellini CB, Romani RL. .
View in:
Publisher Site Mentions:
-
Sphingosine phosphate lyase insufficiency syndrome: a systematic review. World J Pediatr. 2023 05; 19(5):425-437.
Pournasiri Z, Madani A, Nazarpack F, Sayer JA, Chavoshzadeh Z, Nili F, Tran P, Saba JD, Jamee M. PMID: 36371483.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Neurological Consequences of Sphingosine Phosphate Lyase Insufficiency. Front Cell Neurosci. 2022; 16:938693.
Atreya KB, Saba JD. PMID: 36187293; PMCID: PMC9519528.
View in:
PubMed Mentions:
2
-
Sphingosine Phosphate Lyase Is Upregulated in Duchenne Muscular Dystrophy, and Its Inhibition Early in Life Attenuates Inflammation and Dystrophy in Mdx Mice. Int J Mol Sci. 2022 Jul 08; 23(14).
De la Garza-Rodea AS, Moore SA, Zamora-Pineda J, Hoffman EP, Mistry K, Kumar A, Strober JB, Zhao P, Suh JH, Saba JD. PMID: 35886926; PMCID: PMC9316262.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Analyzing Opposing Interactions Between Sphingosine 1-Phosphate Lyase and Influenza A Virus. DNA Cell Biol. 2022 Apr; 41(4):331-335.
Wolf JJ, Saba JD, Hahm B. PMID: 35325556; PMCID: PMC9063141.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
521: Dual targeting of host and fungal sphingosine-1-phosphate lyase as antifungal strategy in cystic fibrosis. Journal of Cystic Fibrosis. 2021 Nov 1; 20:s246-s247.
Costantini CC, Pariano PM, Pampalone PG, Zelante ZT, Macchioni ML, Galarini GR, Costanzi CE, Bellet BM, Giovagnoli GS, Saba SJ, Cellini CB, Romani RL. .
View in:
Publisher Site Mentions:
-
Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile. Int J Mol Sci. 2021 Sep 30; 22(19).
Spohner AK, Jakobi K, Trautmann S, Thomas D, Schumacher F, Kleuser B, Lütjohann D, El-Hindi K, Grösch S, Pfeilschifter J, Saba JD, Meyer Zu Heringdorf D. PMID: 34638955; PMCID: PMC8508615.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Genotype/Phenotype Interactions and First Steps Toward Targeted Therapy for Sphingosine Phosphate Lyase Insufficiency Syndrome. Cell Biochem Biophys. 2021 Sep; 79(3):547-559.
Saba JD, Keller N, Wang JY, Tang F, Slavin A, Shen Y. PMID: 34133011.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome. JCI Insight. 2021 04 22; 6(8).
Zhao P, Tassew GB, Lee JY, Oskouian B, Muñoz DP, Hodgin JB, Watson GL, Tang F, Wang JY, Luo J, Yang Y, King S, Krauss RM, Keller N, Saba JD. PMID: 33755599; PMCID: PMC8119223.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
MRI Spectrum of Brain Involvement in Sphingosine-1-Phosphate Lyase Insufficiency Syndrome. AJNR Am J Neuroradiol. 2020 10; 41(10):1943-1948.
Martin KW, Weaver N, Alhasan K, Gumus E, Sullivan BR, Zenker M, Hildebrandt F, Saba JD. PMID: 32855188; PMCID: PMC7661081.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation. J Inherit Metab Dis. 2020 09; 43(5):1131-1142.
Zhao P, Liu ID, Hodgin JB, Benke PI, Selva J, Torta F, Wenk MR, Endrizzi JA, West O, Ou W, Tang E, Goh DL, Tay SK, Yap HK, Loh A, Weaver N, Sullivan B, Larson A, Cooper MA, Alhasan K, Alangari AA, Salim S, Gumus E, Chen K, Zenker M, Hildebrandt F, Saba JD. PMID: 32233035; PMCID: PMC8072405.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Correction to: Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway. Invest New Drugs. 2019 Dec; 37(6):1309.
Zhao P, Aguilar AE, Lee JY, Paul LA, Suh JH, Puri L, Zhang M, Beckstead J, Witkowski A, Ryan RO, Saba JD. PMID: 31032525.
View in:
PubMed Mentions: Fields:
-
Unraveling the β-amyloid clearance by astrocytes: Involvement of metabotropic glutamate receptor 3, sAPPα, and class-A scavenger receptor. Neurochem Int. 2019 12; 131:104547.
Durand D, Turati J, Rudi MJ, Ramírez D, Saba J, Caruso C, Carniglia L, von Bernhardi R, Lasaga M. PMID: 31536785.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine 1-phosphate lyase promotes the type I interferon-mediated innate immune response to influenza but is subjected to degradation by influenza A virus NS1. The Journal of Immunology. 2019 May 1; 202(1_Supplement):74.10-74.10.
Wolf WJ, Xia XC, Vijayan VM, Song SY, Studstill SC, Ngo NH, Johnson JM, Saba SJ, Alexander AS, Hahm HB. .
View in:
Publisher Site Mentions:
-
Fifty years of lyase and a moment of truth: sphingosine phosphate lyase from discovery to disease. J Lipid Res. 2019 03; 60(3):456-463.
Saba JD. PMID: 30635364; PMCID: PMC6399507.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimals
-
Sphingosine phosphate lyase insufficiency syndrome (SPLIS): A novel inborn error of sphingolipid metabolism. Adv Biol Regul. 2019 01; 71:128-140.
Choi YJ, Saba JD. PMID: 30274713; PMCID: PMC6347531.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
-
Astrocyte truncated tropomyosin receptor kinase B mediates brain-derived neurotrophic factor anti-apoptotic effect leading to neuroprotection. J Neurochem. 2018 09; 146(6):686-702.
Saba J, Turati J, Ramírez D, Carniglia L, Durand D, Lasaga M, Caruso C. PMID: 29851427.
View in:
PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
-
Sphingosine-1-Phosphate Signaling and Metabolism Gene Signature in Pediatric Inflammatory Bowel Disease: A Matched-case Control Pilot Study. Inflamm Bowel Dis. 2018 05 18; 24(6):1321-1334.
Suh JH, Degagné É, Gleghorn EE, Setty M, Rodriguez A, Park KT, Verstraete SG, Heyman MB, Patel AS, Irek M, Gildengorin GL, Hubbard NE, Borowsky AD, Saba JD. PMID: 29788359; PMCID: PMC5986285.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
-
Sphingadienes show therapeutic efficacy in neuroblastoma in vitro and in vivo by targeting the AKT signaling pathway. Invest New Drugs. 2018 10; 36(5):743-754.
Zhao P, Aguilar AE, Lee JY, Paul LA, Suh JH, Puri L, Zhang M, Beckstead J, Witkowski A, Ryan RO, Saba JD. PMID: 29335887; PMCID: PMC6047934.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-Phosphate. Encyclopedia of Signaling Molecules. 2018 Jan 1; 5128-5137.
Kumar KA, Saba SJ. .
View in:
Publisher Site Mentions:
-
S100 Calcium Binding Protein A6. . 2018 Jan 1; 4793-4793.
Dempsey DB, Rintala-Dempsey RA, Shaw SG, Prudovsky PI, Suresh Kumar ST, Donato DR, Donato DR, Sorci SG, Giambanco GI, Pavan PI, Silva SF, Morelli MA, Simabuco SF, Zhu ZY, Keith Stewart KA, Claudio CJ, Runyan RC, William Schnaper WH, Singh SS, Sahoo SS, Periasamy PM, Zádor ZE, Kósa KM, Chen CC, Hsueh HY, Popeijus PH, Guyon GA, Miller ML, Hannila HS, Menon MM, Yamashita YA, Janssens JV, Czekay CR, Simone ST, Higgins HP, Della-Morte DD, Pastore PD, Capuani CB, Pacifici PF, Lauro LD, Charreau CB, King KP, Blunt BM, Ward WS, Erneux EC, Schurmans SS, Rousseaux RC, Saito SY, Murata MY, Kotani KT, Matozaki MT, Gomes GP, Chu CX, George GR, Raju RR, Reinhold RA, Schraven SB, Sorribas SV, Jalloul JA, Szerencsei SR, Rogasevskaia RT, Schnetkamp SP, Yao YS, Young YJ, Gasnier GB, Forster FI, Werner WA, de La Ballina dL, de Garay dT, Féral FC, Palacín PM, Landau LM, Fukuda FM, Lee LJ, Tamaddon-Jahromi TS, Kanamarlapudi KV, Strebovsky SJ, Zimmer ZJ, Dalpke DA, Mariniello MB, Ryan RK, Chiang CC, Colotti CG, Ilari IA, Shimozaki SK, Koizume KS, Miyagi MY, Czogalla CA, Beckmann BN, Gulbins GE, Becker BK, Carpinteiro CA, Neubauer NH, Pitson PS, Kumar KA, Saba SJ, Masoumi-Moghaddam MS, Amini AA, Moharram MS, Rönnstrand RL, Kazi KJ, Moharram MS, Rönnstrand RL, Kazi KJ, Jans JD, Kaur KG, Poderoso PC, Castillo CA, Mele MP, Maloberti MP, Podestá PE, Lim LS, Li LW, Skalkoyannis SB, Kanamarlapudi KV, Tetel TM, Lai LP, Kurup KP, Xu XJ, Chatterjee CM, Goebel-Goody GS, Paul PS, Lombroso LP, Brooks BW, Mukherjee MS, Kloc KM, Kubiak KJ, Ragno RP, Zhang ZJ, Ye YZ, Bowers BR, Townsend TD, Tew TK, Laukkanen LM, Parascandolo PA, Swain SN, Hosalkar HR, Sen SP, Chatterjee CN, Bartholomew BB, Geahlen GR, Bernardo BA, Prashar PS, Molinaro ML, Mishra MR, Song SS, Augustine AG, Swain SN, Hosalkar HR, Routray RS, Drouet DV, Lesage LS, Brice BA, Horowitz HA. .
View in:
Publisher Site Mentions:
-
The low down on sphingosine-1-phosphate lyase as a regulator of thymic egress. J Immunol Sci. 2017; 1(1):1-8.
Saba JD. PMID: 30740601; PMCID: PMC6364841.
View in:
PubMed Mentions:
3
-
S1P Lyase Regulation of Thymic Egress and Oncogenic Inflammatory Signaling. Mediators Inflamm. 2017; 2017:7685142.
Kumar A, Zamora-Pineda J, Degagné E, Saba JD. PMID: 29333002; PMCID: PMC5733215.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
-
Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity. J Biol Chem. 2017 12 08; 292(49):20292-20304.
Hahn C, Tyka K, Saba JD, Lenzen S, Gurgul-Convey E. PMID: 29070677; PMCID: PMC5724014.
View in:
PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
An LC/MS/MS method for quantitation of chemopreventive sphingadienes in food products and biological samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 01; 1061-1062:292-299.
Suh JH, Makarova AM, Gomez JM, Paul LA, Saba JD. PMID: 28772225; PMCID: PMC5656051.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production. Autophagy. 2017 May 04; 13(5):885-899.
Mitroi DN, Karunakaran I, Gräler M, Saba JD, Ehninger D, Ledesma MD, van Echten-Deckert G. PMID: 28521611; PMCID: PMC5446076.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
-
Obinutuzumab-induced serum sickness following salvage therapy for chronic lymphocytic leukemia. Clin Case Rep. 2017 06; 5(6):891-893.
Saba J, Logan AC. PMID: 28588833; PMCID: PMC5457998.
View in:
PubMed Mentions:
2
-
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency. J Clin Invest. 2017 Mar 01; 127(3):912-928.
Lovric S, Goncalves S, Gee HY, Oskouian B, Srinivas H, Choi WI, Shril S, Ashraf S, Tan W, Rao J, Airik M, Schapiro D, Braun DA, Sadowski CE, Widmeier E, Jobst-Schwan T, Schmidt JM, Girik V, Capitani G, Suh JH, Lachaussée N, Arrondel C, Patat J, Gribouval O, Furlano M, Boyer O, Schmitt A, Vuiblet V, Hashmi S, Wilcken R, Bernier FP, Innes AM, Parboosingh JS, Lamont RE, Midgley JP, Wright N, Majewski J, Zenker M, Schaefer F, Kuss N, Greil J, Giese T, Schwarz K, Catheline V, Schanze D, Franke I, Sznajer Y, Truant AS, Adams B, Désir J, Biemann R, Pei Y, Ars E, Lloberas N, Madrid A, Dharnidharka VR, Connolly AM, Willing MC, Cooper MA, Lifton RP, Simons M, Riezman H, Antignac C, Saba JD, Hildebrandt F. PMID: 28165339; PMCID: PMC5330730.
View in:
PubMed Mentions:
99 Fields:
Translation:
HumansAnimalsCells
-
Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases. Mediators Inflamm. 2017; 2017:5048616.
Carniglia L, Ramírez D, Durand D, Saba J, Turati J, Caruso C, Scimonelli TN, Lasaga M. PMID: 28154473; PMCID: PMC5244030.
View in:
PubMed Mentions:
94 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism. Sci Rep. 2016 11 24; 6:37064.
Mitroi DN, Deutschmann AU, Raucamp M, Karunakaran I, Glebov K, Hans M, Walter J, Saba J, Gräler M, Ehninger D, Sopova E, Shupliakov O, Swandulla D, van Echten-Deckert G. PMID: 27883090; PMCID: PMC5121647.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
-
Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. J Exp Med. 2016 11 14; 213(12):2773-2791.
Zamora-Pineda J, Kumar A, Suh JH, Zhang M, Saba JD. PMID: 27810923; PMCID: PMC5110016.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
-
Sphingosine-1-Phosphate. Encyclopedia of Signaling Molecules. 2016 Jan 1; 1-10.
Kumar KA, Saba SJ. .
View in:
Publisher Site Mentions:
-
Regulation of Immune Cell Migration by Sphingosine-1-Phosphate. Cell Mol Biol (OMICS). 2015; 61(2).
Kumar A, Saba JD. PMID: 30294722; PMCID: PMC6169313.
View in:
PubMed Mentions:
15
-
Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat's in the fire. Transl Cancer Res. 2015 Oct 01; 4(5):469-483.
Suh JH, Saba JD. PMID: 27011900; PMCID: PMC4800486.
View in:
PubMed Mentions:
25
-
A facile stable-isotope dilution method for determination of sphingosine phosphate lyase activity. Chem Phys Lipids. 2016 Jan; 194:101-9.
Suh JH, Eltanawy A, Rangan A, Saba JD. PMID: 26408264; PMCID: PMC4718852.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
A B cell-dependent mechanism restrains T cell transendothelial migration. Nat Med. 2015 May; 21(5):424-6.
Saba JD. PMID: 25951526; PMCID: PMC5980639.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs. J Clin Invest. 2014 Dec; 124(12):5368-84.
Degagné E, Pandurangan A, Bandhuvula P, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, de Jong PJ, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD. PMID: 25347472; PMCID: PMC4348973.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
-
Tracking hippo in the cancer jungle. Chem Biol. 2014 Jul 17; 21(7):803-4.
Suh JH, Saba JD. PMID: 25036773; PMCID: PMC5982109.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
S1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancer. Clin Exp Gastroenterol. 2014; 7:205-14.
Degagné E, Saba JD. PMID: 25061328; PMCID: PMC4085325.
View in:
PubMed Mentions:
31
-
Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression. FASEB J. 2014 Jan; 28(1):506-19.
de la Garza-Rodea AS, Baldwin DM, Oskouian B, Place RF, Bandhuvula P, Kumar A, Saba JD. PMID: 24158395; PMCID: PMC3868843.
View in:
PubMed Mentions:
9 Fields:
Translation:
Animals
-
Sphingosine Phosphate Lyase Regulates Murine Embryonic Stem Cell Proliferation and Pluripotency through an S1P2/STAT3 Signaling Pathway. Biomolecules. 2013 Jun 24; 3(3):351-368.
Smith GS, Kumar A, Saba JD. PMID: 24619572; PMCID: PMC3947625.
View in:
PubMed Mentions:
14 Fields:
-
A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity. Mol Cell Biol. 2013 Feb; 33(4):752-62.
Park K, Elias PM, Shin KO, Lee YM, Hupe M, Borkowski AW, Gallo RL, Saba J, Holleran WM, Uchida Y. PMID: 23230267; PMCID: PMC3571353.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
-
Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development. Gene Expr Patterns. 2013 Jan-Feb; 13(1-2):21-9.
Newbigging S, Zhang M, Saba JD. PMID: 23041657; PMCID: PMC3562366.
View in:
PubMed Mentions:
6 Fields:
Translation:
Animals
-
Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues. J Lipid Res. 2012 Sep; 53(9):1920-31.
Borowsky AD, Bandhuvula P, Kumar A, Yoshinaga Y, Nefedov M, Fong LG, Zhang M, Baridon B, Dillard L, de Jong P, Young SG, West DB, Saba JD. PMID: 22781001; PMCID: PMC3413231.
View in:
PubMed Mentions:
26 Fields:
Translation:
Animals
-
S1P lyase in skeletal muscle regeneration and satellite cell activation: exposing the hidden lyase. Biochim Biophys Acta. 2013 Jan; 1831(1):167-75.
Saba JD, de la Garza-Rodea AS. PMID: 22750505; PMCID: PMC3609719.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
The sphingolipid degradation product trans-2-hexadecenal forms adducts with DNA. Biochem Biophys Res Commun. 2012 Jul 20; 424(1):18-21.
Upadhyaya P, Kumar A, Byun HS, Bittman R, Saba JD, Hecht SS. PMID: 22727907; PMCID: PMC3402648.
View in:
PubMed Mentions:
18 Fields:
-
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. PLoS One. 2012; 7(5):e37218.
Loh KC, Leong WI, Carlson ME, Oskouian B, Kumar A, Fyrst H, Zhang M, Proia RL, Hoffman EP, Saba JD. PMID: 22606352; PMCID: PMC3351440.
View in:
PubMed Mentions:
43 Fields:
Translation:
AnimalsCells
-
Chemopreventive sphingadienes downregulate Wnt signaling via a PP2A/Akt/GSK3β pathway in colon cancer. Carcinogenesis. 2012 Sep; 33(9):1726-35.
Kumar A, Pandurangan AK, Lu F, Fyrst H, Zhang M, Byun HS, Bittman R, Saba JD. PMID: 22581840; PMCID: PMC3514901.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCells
-
Truth and consequences of sphingosine-1-phosphate lyase. Adv Biol Regul. 2012 Jan; 52(1):17-30.
Aguilar A, Saba JD. PMID: 21946005; PMCID: PMC3560305.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-Phosphate. Encyclopedia of Signaling Molecules. 2012 Jan 1; 1771-1778.
Dempsey DB, Rintala-Dempsey RA, Shaw SG, Zhu ZY, Stewart SA, Claudio CJ, Runyan RC, Schnaper SH, King KP, Blunt BM, Ward WS, Reinhold RA, Schraven SB, Fukuda FM, Lee LJ, Strebovsky SJ, Dalpke DA, Mariniello MB, Ryan RK, Chiang CC, Kumar KA, Saba SJ, Jans JD, Kaur KG, Tetel TM, Lai LP, Kurup KP, Xu XJ, Goebel-Goody GS, Paul PS, Lombroso LP, Ragno RP, Bowers BR, Townsend TD, Tew TK, Sen SP, Chatterjee CN, Bartholomew BB, Horowitz HA. .
View in:
Publisher Site Mentions:
-
Corrigendum to “The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner” [Cell. Signal. 23(7) (2011) 1144-1152]. Cellular Signalling. 2012 Jan 1; 24(1):351.
Kumar KA, Byun BH, Bittman BR, Saba SJ. .
View in:
Publisher Site Mentions:
-
S100 Calcium-Binding Protein. . 2012 Jan 1; 1711-1711.
Dempsey DB, Rintala-Dempsey RA, Shaw SG, Zhu ZY, Stewart SA, Claudio CJ, Runyan RC, Schnaper SH, King KP, Blunt BM, Ward WS, Reinhold RA, Schraven SB, Fukuda FM, Lee LJ, Strebovsky SJ, Dalpke DA, Mariniello MB, Ryan RK, Chiang CC, Kumar KA, Saba SJ, Jans JD, Kaur KG, Tetel TM, Lai LP, Kurup KP, Xu XJ, Goebel-Goody GS, Paul PS, Lombroso LP, Ragno RP, Bowers BR, Townsend TD, Tew TK, Sen SP, Chatterjee CN, Bartholomew BB, Horowitz HA. .
View in:
Publisher Site Mentions:
-
A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. PLoS One. 2011; 6(11):e26993.
McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. PMID: 22069480; PMCID: PMC3206050.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond. Anticancer Agents Med Chem. 2011 Nov; 11(9):782-93.
Loh KC, Baldwin D, Saba JD. PMID: 21707493; PMCID: PMC3259192.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
-
A monoclonal antibody to O-acetyl-GD2 ganglioside and not to GD2 shows potent anti-tumor activity without peripheral nervous system cross-reactivity. PLoS One. 2011; 6(9):e25220.
Alvarez-Rueda N, Desselle A, Cochonneau D, Chaumette T, Clemenceau B, Leprieur S, Bougras G, Supiot S, Mussini JM, Barbet J, Saba J, Paris F, Aubry J, Birklé S. PMID: 21966461; PMCID: PMC3178631.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansCells
-
S1P lyase regulates DNA damage responses in vitro and in vivo. The FASEB Journal. 2011 Apr 1; 25:197.1-197.1.
Saba SJ, Kumar KA, Oskouian OB, Fyrst FH, Zhang ZM. .
View in:
Publisher Site Mentions:
-
The sphingolipid degradation product trans-2-hexadecenal induces cytoskeletal reorganization and apoptosis in a JNK-dependent manner. Cell Signal. 2011 Jul; 23(7):1144-52.
Kumar A, Byun HS, Bittman R, Saba JD. PMID: 21385609; PMCID: PMC3086202.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
-
S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart. Am J Physiol Heart Circ Physiol. 2011 May; 300(5):H1753-61.
Bandhuvula P, Honbo N, Wang GY, Jin ZQ, Fyrst H, Zhang M, Borowsky AD, Dillard L, Karliner JS, Saba JD. PMID: 21335477; PMCID: PMC3094087.
View in:
PubMed Mentions:
42 Fields:
Translation:
Animals
-
S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism. Cell Death Dis. 2011 Feb 10; 2:e119.
Kumar A, Oskouian B, Fyrst H, Zhang M, Paris F, Saba JD. PMID: 21368890; PMCID: PMC3101703.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking. J Biol Chem. 2011 Mar 04; 286(9):7348-58.
Allende ML, Bektas M, Lee BG, Bonifacino E, Kang J, Tuymetova G, Chen W, Saba JD, Proia RL. PMID: 21173151; PMCID: PMC3044991.
View in:
PubMed Mentions:
97 Fields:
Translation:
AnimalsCells
-
Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):426-35.
Zhao Y, Gorshkova IA, Berdyshev E, He D, Fu P, Ma W, Su Y, Usatyuk PV, Pendyala S, Oskouian B, Saba JD, Garcia JG, Natarajan V. PMID: 21148740; PMCID: PMC3175568.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
-
Erratum: An update on sphingosine-1-phosphate and other sphingolipid mediators. Nature Chemical Biology. 2010 Sep 1; 6(9):689-689.
Fyrst FH, Saba SJ. .
View in:
Publisher Site Mentions:
-
An update on sphingosine-1-phosphate and other sphingolipid mediators. Nat Chem Biol. 2010 Jul; 6(7):489-97.
Fyrst H, Saba JD. PMID: 20559316; PMCID: PMC3001344.
View in:
PubMed Mentions:
164 Fields:
Translation:
HumansAnimals
-
S1P metabolism in cancer and other pathological conditions. Biochimie. 2010 Jun; 92(6):716-23.
Leong WI, Saba JD. PMID: 20167244; PMCID: PMC2878883.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
-
Synopsis of partial-body radiation diagnostic biomarkers and medical management of radiation injury workshop. Radiat Res. 2010 Feb; 173(2):245-53.
Prasanna PG, Blakely WF, Bertho JM, Chute JP, Cohen EP, Goans RE, Grace MB, Lillis-Hearne PK, Lloyd DC, Lutgens LC, Meineke V, Ossetrova NI, Romanyukha A, Saba JD, Weisdorf DJ, Wojcik A, Yukihara EG, Pellmar TC. PMID: 20095857; PMCID: PMC8914528.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansPHPublic Health
-
Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver. J Biol Chem. 2010 Apr 02; 285(14):10880-9.
Bektas M, Allende ML, Lee BG, Chen W, Amar MJ, Remaley AT, Saba JD, Proia RL. PMID: 20097939; PMCID: PMC2856294.
View in:
PubMed Mentions:
111 Fields:
Translation:
AnimalsCells
-
Cancer treatment strategies targeting sphingolipid metabolism. Adv Exp Med Biol. 2010; 688:185-205.
Oskouian B, Saba JD. PMID: 20919655; PMCID: PMC3076281.
View in:
PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
-
Natural sphingadienes inhibit Akt-dependent signaling and prevent intestinal tumorigenesis. Cancer Res. 2009 Dec 15; 69(24):9457-64.
Fyrst H, Oskouian B, Bandhuvula P, Gong Y, Byun HS, Bittman R, Lee AR, Saba JD. PMID: 19934323; PMCID: PMC2795098.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function. Adv Enzyme Regul. 2010; 50(1):349-62.
Serra M, Saba JD. PMID: 19914275; PMCID: PMC2862839.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
-
Normalization of diabetic wound healing. Surgery. 2010 Mar; 147(3):446-9.
Francis-Goforth KN, Harken AH, Saba JD. PMID: 19703697; PMCID: PMC2827630.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Lyase to live by: sphingosine phosphate lyase as a therapeutic target. Expert Opin Ther Targets. 2009 Aug; 13(8):1013-25.
Kumar A, Saba JD. PMID: 19534571; PMCID: PMC2774446.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate. Biochem Biophys Res Commun. 2009 Mar 06; 380(2):366-70.
Bandhuvula P, Li Z, Bittman R, Saba JD. PMID: 19250638; PMCID: PMC2790368.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
-
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circ Res. 2008 Nov 07; 103(10):1164-72.
Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D. PMID: 18849324; PMCID: PMC2708004.
View in:
PubMed Mentions:
116 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-phosphate lyase in development and disease: sphingolipid metabolism takes flight. Biochim Biophys Acta. 2008 Sep; 1781(9):448-58.
Fyrst H, Saba JD. PMID: 18558101; PMCID: PMC2749932.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
-
Identification and characterization by electrospray mass spectrometry of endogenous Drosophila sphingadienes. J Lipid Res. 2008 Mar; 49(3):597-606.
Fyrst H, Zhang X, Herr DR, Byun HS, Bittman R, Phan VH, Harris GL, Saba JD. PMID: 18156591.
View in:
PubMed Mentions:
28 Fields:
Translation:
Animals
-
A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity. J Lipid Res. 2007 Dec; 48(12):2769-78.
Bandhuvula P, Fyrst H, Saba JD. PMID: 17872591.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
-
Disruption of sphingolipid metabolism elicits apoptosis-associated reproductive defects in Drosophila. Dev Biol. 2007 Sep 15; 309(2):329-41.
Phan VH, Herr DR, Panton D, Fyrst H, Saba JD, Harris GL. PMID: 17706961; PMCID: PMC2094363.
View in:
PubMed Mentions:
31 Fields:
Translation:
Animals
-
Sphingosine-1-phosphate lyase in immunity and cancer: silencing the siren. Trends Mol Med. 2007 May; 13(5):210-7.
Bandhuvula P, Saba JD. PMID: 17416206.
View in:
PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine-1-phosphate metabolism and intestinal tumorigenesis: lipid signaling strikes again. Cell Cycle. 2007 Mar 01; 6(5):522-7.
Oskouian B, Saba J. PMID: 17361098.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania. EMBO J. 2007 Feb 21; 26(4):1094-104.
Zhang K, Pompey JM, Hsu FF, Key P, Bandhuvula P, Saba JD, Turk J, Beverley SM. PMID: 17290222; PMCID: PMC1852826.
View in:
PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
-
Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17384-9.
Oskouian B, Sooriyakumaran P, Borowsky AD, Crans A, Dillard-Telm L, Tam YY, Bandhuvula P, Saba JD. PMID: 17090686; PMCID: PMC1859938.
View in:
PubMed Mentions:
122 Fields:
Translation:
HumansAnimalsCells
-
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation. Mol Cell Biol. 2006 Oct; 26(19):7211-23.
Kohno M, Momoi M, Oo ML, Paik JH, Lee YM, Venkataraman K, Ai Y, Ristimaki AP, Fyrst H, Sano H, Rosenberg D, Saba JD, Proia RL, Hla T. PMID: 16980623; PMCID: PMC1592880.
View in:
PubMed Mentions:
110 Fields:
Translation:
HumansAnimalsCells
-
Sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 signaling in rheumatoid synovium: regulation of synovial proliferation and inflammatory gene expression. Arthritis Rheum. 2006 Mar; 54(3):742-53.
Kitano M, Hla T, Sekiguchi M, Kawahito Y, Yoshimura R, Miyazawa K, Iwasaki T, Sano H, Saba JD, Tam YY. PMID: 16508938.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansCells
-
S1P Lyase Expression Hypersensitizes Cells to DNA Damage and Other Stress Conditions via p53 and p38 Apoptosis Pathways. The FASEB Journal. 2006 Mar 1; 20(4):a33-a34.
Saba SJ, Oskouian OB, Sooriyakumaran SP. .
View in:
Publisher Site Mentions:
-
Sphingosine-1-Phosphate Lyase. Sphingolipid Biology. 2006 Jan 1; 219-230.
Saba SJ. .
View in:
Publisher Site Mentions:
-
Directed Donor Cord Blood Transplantation for Hematological Disorders. Blood. 2005 Nov 16; 106(11):2035-2035.
Walters WM, Quirolo QL, Edwards ES, Lee LJ, Robertson RS, Saba SJ, Trachtenberg TE, Quirolo QK, Lubin LB. .
View in:
Publisher Site Mentions:
-
The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity. J Biol Chem. 2005 Oct 07; 280(40):33697-700.
Bandhuvula P, Tam YY, Oskouian B, Saba JD. PMID: 16118221.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
-
Regulation of sphingosine-1-phosphate lyase gene expression by members of the GATA family of transcription factors. J Biol Chem. 2005 May 06; 280(18):18403-10.
Oskouian B, Mendel J, Shocron E, Lee MA, Fyrst H, Saba JD. PMID: 15734735.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
-
Sibling donor cord blood transplantation for thalassemia major: Experience of the Sibling Donor Cord Blood Program. Ann N Y Acad Sci. 2005; 1054:206-13.
Walters MC, Quirolo L, Trachtenberg ET, Edwards S, Hale L, Lee J, Morton-Wiley J, Quirolo K, Robertson S, Saba J, Lubin B. PMID: 16339667.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17825-30.
Jiang Q, Wong J, Fyrst H, Saba JD, Ames BN. PMID: 15596715; PMCID: PMC535585.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansCells
-
Death and taxis: what non-mammalian models tell us about sphingosine-1-phosphate. Semin Cell Dev Biol. 2004 Oct; 15(5):529-40.
Oskouian B, Saba JD. PMID: 15271298.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansAnimals
-
Lysophospholipids in development: Miles apart and edging in. J Cell Biochem. 2004 Aug 01; 92(5):967-92.
Saba JD. PMID: 15258919.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
-
Point-counterpoint of sphingosine 1-phosphate metabolism. Circ Res. 2004 Apr 02; 94(6):724-34.
Saba JD, Hla T. PMID: 15059942.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansAnimalsCells
-
Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function. J Biol Chem. 2004 Mar 26; 279(13):12685-94.
Herr DR, Fyrst H, Creason MB, Phan VH, Saba JD, Harris GL. PMID: 14722126.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. J Biol Chem. 2004 Jan 09; 279(2):1281-90.
Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, Wang E, Merrill AH, Saba JD. PMID: 14570870.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
-
Characterization of free endogenous C14 and C16 sphingoid bases from Drosophila melanogaster. J Lipid Res. 2004 Jan; 45(1):54-62.
Fyrst H, Herr DR, Harris GL, Saba JD. PMID: 13130120.
View in:
PubMed Mentions:
30 Fields:
Translation:
Animals
-
Sply regulation of sphingolipid signaling molecules is essential for Drosophila development. Development. 2003 Jun; 130(11):2443-53.
Herr DR, Fyrst H, Phan V, Heinecke K, Georges R, Harris GL, Saba JD. PMID: 12702658.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
Sphingosine phosphate lyase expression is essential for normal development in Caenorhabditis elegans. J Biol Chem. 2003 Jun 20; 278(25):22341-9.
Mendel J, Heinecke K, Fyrst H, Saba JD. PMID: 12682045.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
-
Comprehensive banking of sibling donor cord blood for children with malignant and nonmalignant disease. Blood. 2003 Jan 01; 101(1):351-7.
Reed W, Smith R, Dekovic F, Lee JY, Saba JD, Trachtenberg E, Epstein J, Haaz S, Walters MC, Lubin BH. PMID: 12393579.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. J Biol Chem. 2001 Apr 13; 276(15):11712-8.
Birchwood CJ, Saba JD, Dickson RC, Cunningham KW. PMID: 11278643.
View in:
PubMed Mentions:
32 Fields:
Translation:
Cells
-
Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae. Genetics. 2000 Dec; 156(4):1519-29.
Kim S, Fyrst H, Saba J. PMID: 11102354; PMCID: PMC1461366.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
-
Molecular cloning - and functional characterization of the human sphingosine-1 -phosphate lyase gene. Journal of Pediatric Hematology/Oncology. 2000 Jul 1; 22(4):382.
Zhou ZJ, Reiss RU, Saba SJ. .
View in:
Publisher Site Mentions:
-
A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples. Anal Biochem. 2000 May 15; 281(1):36-44.
Caligan TB, Peters K, Ou J, Wang E, Saba J, Merrill AH. PMID: 10847608.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. Biochemical Journal. 1999 Sep 15; 342(3):667-675.
Cungui CM, SABA SJ, OBEID OL. .
View in:
Publisher Site Mentions:
-
The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. Biochem J. 1999 Sep 15; 342 Pt 3:667-75.
Mao C, Saba JD, Obeid LM. PMID: 10477278; PMCID: PMC1220508.
View in:
PubMed Mentions:
38 Fields:
Translation:
AnimalsCells
-
The PLB2 gene of Saccharomyces cerevisiae confers resistance to lysophosphatidylcholine and encodes a phospholipase B/lysophospholipase. Biochemistry. 1999 May 04; 38(18):5864-71.
Fyrst H, Oskouian B, Kuypers FA, Saba JD. PMID: 10231538.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
-
The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae. Mol Cell Biol Res Commun. 1999 Apr; 1(1):66-71.
Gottlieb D, Heideman W, Saba JD. PMID: 10329480.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
YAP1 confers resistance to the fatty acid synthase inhibitor cerulenin through the transporter Flr1p in Saccharomyces cerevisiae. Mol Gen Genet. 1999 Mar; 261(2):346-53.
Oskouian B, Saba JD. PMID: 10102370.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. Biochem J. 1998 Jun 01; 332 ( Pt 2):525-31.
Lanterman MM, Saba JD. PMID: 9601083; PMCID: PMC1219509.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
-
Cost-effectiveness of antiviral drug therapy to reduce mother-to-child HIV transmission in sub-Saharan Africa. AIDS. 1998 May 28; 12(8):939-48.
Marseille E, Kahn JG, Saba J. PMID: 9631148.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansPHPublic Health
-
Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast. Biochem Biophys Res Commun. 1998 Jan 26; 242(3):502-7.
Zhou J, Saba JD. PMID: 9464245.
View in:
PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
-
The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase. J Biol Chem. 1997 Oct 17; 272(42):26087-90.
Saba JD, Nara F, Bielawska A, Garrett S, Hannun YA. PMID: 9334171.
View in:
PubMed Mentions:
82 Fields:
Translation:
Animals
-
Ceramide: an intracellular mediator of apoptosis and growth suppression. Philos Trans R Soc Lond B Biol Sci. 1996 Feb 29; 351(1336):233-40; discussion 240-1.
Saba JD, Obeid LM, Hannun YA. PMID: 8650271.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae. J Biol Chem. 1993 May 05; 268(13):9255-61.
Fishbein JD, Dobrowsky RT, Bielawska A, Garrett S, Hannun YA. PMID: 8387486.
View in:
PubMed Mentions:
35 Fields:
Translation:
Animals
-
A seven-month-old infant with fever and neutrophilic leukocytosis. J Pediatr. 1992 May; 120(5):819-24.
Fishbein JD, Bruggers CS, Friedman NJ, Graham ML, Kurtzberg J. PMID: 1578323.
View in:
PubMed Mentions: Fields:
Translation:
HumansCells
-
Large-cell lymphoma presenting with a distinctive inflammatory dermatosis. J Am Acad Dermatol. 1991 Nov; 25(5 Pt 2):912-5.
Tope WD, Fishbein JD, White PF, Prose NS. PMID: 1761769.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Pelger-Huet anomaly in an infant with multiple congenital anomalies. Am J Hematol. 1991 Nov; 38(3):240-2.
Fishbein JD, Falletta JM. PMID: 1951327.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
A piece of my mind. The poetry of medicine. JAMA. 1990 Dec 19; 264(23):2999.
Fishbein J. PMID: 2243427.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Catheter-related sepsis refractory to antibiotics treated successfully with adjunctive urokinase infusion. Pediatr Infect Dis J. 1990 Sep; 9(9):676-8.
Fishbein JD, Friedman HS, Bennett BB, Falletta JM. PMID: 2235195.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Indicator enzyme assays. II. Adenylate kinase: application to human muscle biopsies and blood cells. Biochem Med. 1980 Oct; 24(2):130-42.
Fishbein WN, Davis JI, Winkert JW, Fishbein JD. PMID: 6257235.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Sphingosine-1-phosphate signaling and metabolism gene signature in pediatric inflammatory bowel disease: a matched-case control pilot study. in press.
Suh JH
Degagné E
Gleghorn EE
Setty M
Rodriguez A
Park KT
Verstraete SG
Heyman MB
Patel AS
Irek M
Gildengorin GL
Hubbard NE
Borowsky AD
Saba JD.
-
Journal of Immunological Sciences. The low down on sphingosine-1-phosphate lyase as a regulator of thymic egress. in press.
Saba JD.