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Jun Jie Hua, PhD

Title(s)Postdoctoral Scholar, Radiation Oncology
SchoolSchool of Medicine
Address1450 Third St
San Francisco CA 94158
Phone415-502-6355
ORCID ORCID Icon0000-0002-1197-1174 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Toronto, Toronto, CanadaPhD04/2019Prostate Cancer Epigenetics
    University of Toronto, Toronto, CanadaBSc06/2014Cell and Molecular Biology
    Collapse Awards and Honors
    Prostate Cancer Foundation2019  - 2022PCF Young Investigator Award
    Canadian Institute of Health Research2016  - 2019Frederick Banting and Charles Best Canada Graduate Doctoral Scholarship
    Canadian Institute of Health Research2015  - 2016Frederick Banting and Charles Best Canada Graduate Master’s Scholarship

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer. Nat Commun. 2021 03 19; 12(1):1781. Ahmed M, Soares F, Xia JH, Yang Y, Li J, Guo H, Su P, Tian Y, Lee HJ, Wang M, Akhtar N, Houlahan KE, Bosch A, Zhou S, Mazrooei P, Hua JT, Chen S, Petricca J, Zeng Y, Davies A, Fraser M, Quigley DA, Feng FY, Boutros PC, Lupien M, Zoubeidi A, Wang L, Walsh MJ, Wang T, Ren S, Wei GH, He HH. PMID: 33741908.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. Molecular imaging of prostate cancer targeting CD46 using immunoPET. Clin Cancer Res. 2020 Dec 08. Wang S, Li J, Hua J, Su Y, Beckford Vera DR, Zhao W, Jayaraman M, Huynh TL, Zhao N, Wang YH, Huang Y, Qin F, Shen S, Gioeli D, Dreicer R, Sriram R, Egusa EA, Chou J, Feng FY, Aggarwal R, Evans MJ, Seo Y, Liu B, Flavell RR, He J. PMID: 33293372.
      View in: PubMed   Mentions:    Fields:    
    3. The DNA methylation landscape of advanced prostate cancer. Nat Genet. 2020 08; 52(8):778-789. Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. PMID: 32661416.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer. Nat Commun. 2020 01 23; 11(1):441. Zhou S, Hawley JR, Soares F, Grillo G, Teng M, Madani Tonekaboni SA, Hua JT, Kron KJ, Mazrooei P, Ahmed M, Arlidge C, Yun HY, Livingstone J, Huang V, Yamaguchi TN, Espiritu SMG, Zhu Y, Severson TM, Murison A, Cameron S, Zwart W, van der Kwast T, Pugh TJ, Fraser M, Boutros PC, Bristow RG, He HH, Lupien M. PMID: 31974375.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. Landscape of Noncoding RNA in Prostate Cancer. Trends Genet. 2019 11; 35(11):840-851. Hua JT, Chen S, He HH. PMID: 31623872.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    6. Orphan noncoding RNAs: novel regulators and cancer biomarkers. Ann Transl Med. 2019 Mar; 7(Suppl 1):S21. Teng M, Liu LY, Hua JT, Chen S, He HH. PMID: 31032301.
      View in: PubMed   Mentions:
    7. Widespread and Functional RNA Circularization in Localized Prostate Cancer. Cell. 2019 02 07; 176(4):831-843.e22. Chen S, Huang V, Xu X, Livingstone J, Soares F, Jeon J, Zeng Y, Hua JT, Petricca J, Guo H, Wang M, Yousif F, Zhang Y, Donmez N, Ahmed M, Volik S, Lapuk A, Chua MLK, Heisler LE, Foucal A, Fox NS, Fraser M, Bhandari V, Shiah YJ, Guan J, Li J, Orain M, Picard V, Hovington H, Bergeron A, Lacombe L, Fradet Y, Têtu B, Liu S, Feng F, Wu X, Shao YW, Komor MA, Sahinalp C, Collins C, Hoogstrate Y, de Jong M, Fijneman RJA, Fei T, Jenster G, van der Kwast T, Bristow RG, Boutros PC, He HH. PMID: 30735634.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    8. ONECUT2 is a driver of neuroendocrine prostate cancer. Nat Commun. 2019 01 17; 10(1):278. Guo H, Ci X, Ahmed M, Hua JT, Soares F, Lin D, Puca L, Vosoughi A, Xue H, Li E, Su P, Chen S, Nguyen T, Liang Y, Zhang Y, Xu X, Xu J, Sheahan AV, Ba-Alawi W, Zhang S, Mahamud O, Vellanki RN, Gleave M, Bristow RG, Haibe-Kains B, Poirier JT, Rudin CM, Tsao MS, Wouters BG, Fazli L, Feng FY, Ellis L, van der Kwast T, Berlin A, Koritzinsky M, Boutros PC, Zoubeidi A, Beltran H, Wang Y, He HH. PMID: 30655535.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    9. Refined RIP-seq protocol for epitranscriptome analysis with low input materials. PLoS Biol. 2018 09; 16(9):e2006092. Zeng Y, Wang S, Gao S, Soares F, Ahmed M, Guo H, Wang M, Hua JT, Guan J, Moran MF, Tsao MS, He HH. PMID: 30212448.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19. Cell. 2018 07 26; 174(3):564-575.e18. Hua JT, Ahmed M, Guo H, Zhang Y, Chen S, Soares F, Lu J, Zhou S, Wang M, Li H, Larson NB, McDonnell SK, Patel PS, Liang Y, Yao CQ, van der Kwast T, Lupien M, Feng FY, Zoubeidi A, Tsao MS, Thibodeau SN, Boutros PC, He HH. PMID: 30033362.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    11. LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression. Cancer Res. 2017 10 15; 77(20):5479-5490. Liang Y, Ahmed M, Guo H, Soares F, Hua JT, Gao S, Lu C, Poon C, Han W, Langstein J, Ekram MB, Li B, Davicioni E, Takhar M, Erho N, Karnes RJ, Chadwick D, van der Kwast T, Boutros PC, Arrowsmith CH, Feng FY, Joshua AM, Zoubeidi A, Cai C, He HH. PMID: 28916652.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    12. Noncoding RNA for personalized prostate cancer treatment: utilizing the 'dark matters' of the genome. Per Med. 2017 03; 14(2):159-169. Hua J, Lu J, Isaev K, Soares F, Guo H, Ahmed M, He HH. PMID: 29754555.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Crucial role of noncoding RNA in driving prostate cancer development and progression. Epigenomics. 2017 01; 9(1):1-3. Guo H, Ahmed M, Hua J, Soares F, He HH. PMID: 27885842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer. Nat Genet. 2016 10; 48(10):1142-50. Guo H, Ahmed M, Zhang F, Yao CQ, Li S, Liang Y, Hua J, Soares F, Sun Y, Langstein J, Li Y, Poon C, Bailey SD, Desai K, Fei T, Li Q, Sendorek DH, Fraser M, Prensner JR, Pugh TJ, Pomerantz M, Bristow RG, Lupien M, Feng FY, Boutros PC, Freedman ML, Walsh MJ, He HH. PMID: 27526323.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    15. Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences. PLoS Comput Biol. 2014 Dec; 10(12):e1003977. Nguyen Ba AN, Strome B, Hua JJ, Desmond J, Gagnon-Arsenault I, Weiss EL, Landry CR, Moses AM. PMID: 25474245.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
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