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Kara McKinley, PhD

Title(s)Postdoctoral Scholar, Cellular Molecular Pharmacology
SchoolSchool of Medicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms modulating cell identity in regenerative mammalian epithelia
    NIH/NICHD K99HD101021Sep 30, 2019 - Aug 31, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. McKinley KL, Castillo-Azofeifa D, Klein OD. Tools and Concepts for Interrogating and Defining Cellular Identity. Cell Stem Cell. 2020 May 07; 26(5):632-656. PMID: 32386555.
      View in: PubMed
    2. Rodriguez-Rodriguez JA, Lewis C, McKinley KL, Sikirzhytski V, Corona J, Maciejowski J, Khodjakov A, Cheeseman IM, Jallepalli PV. Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion. Curr Biol. 2018 11 05; 28(21):3422-3429.e5. PMID: 30415700.
      View in: PubMed
    3. McKinley KL, Stuurman N, Royer LA, Schartner C, Castillo-Azofeifa D, Delling M, Klein OD, Vale RD. Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. Elife. 2018 06 13; 7. PMID: 29897330.
      View in: PubMed
    4. McKinley KL. Employing CRISPR/Cas9 genome engineering to dissect the molecular requirements for mitosis. Methods Cell Biol. 2018; 144:75-105. PMID: 29804684.
      View in: PubMed
    5. Guo LY, Allu PK, Zandarashvili L, McKinley KL, Sekulic N, Dawicki-McKenna JM, Fachinetti D, Logsdon GA, Jamiolkowski RM, Cleveland DW, Cheeseman IM, Black BE. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nat Commun. 2017 06 09; 8:15775. PMID: 28598437.
      View in: PubMed
    6. McKinley KL, Cheeseman IM. Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects. Dev Cell. 2017 02 27; 40(4):405-420.e2. PMID: 28216383.
      View in: PubMed
    7. McKinley KL, Cheeseman IM. The molecular basis for centromere identity and function. Nat Rev Mol Cell Biol. 2016 Jan; 17(1):16-29. PMID: 26601620.
      View in: PubMed
    8. McKinley KL, Sekulic N, Guo LY, Tsinman T, Black BE, Cheeseman IM. The CENP-L-N Complex Forms a Critical Node in an Integrated Meshwork of Interactions at the Centromere-Kinetochore Interface. Mol Cell. 2015 Dec 17; 60(6):886-98. PMID: 26698661.
      View in: PubMed
    9. McKinley KL, Cheeseman IM. Polo-like kinase 1 licenses CENP-A deposition at centromeres. Cell. 2014 Jul 17; 158(2):397-411. PMID: 25036634.
      View in: PubMed
    10. Thiru P, Kern DM, McKinley KL, Monda JK, Rago F, Su KC, Tsinman T, Yarar D, Bell GW, Cheeseman IM. Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program. Mol Biol Cell. 2014 Jul 01; 25(13):1983-94. PMID: 24829384.
      View in: PubMed
    11. Fisher MA, McKinley KL, Bradley LH, Viola SR, Hecht MH. De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth. PLoS One. 2011 Jan 04; 6(1):e15364. PMID: 21245923.
      View in: PubMed