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Karen Leung, PhD

TitleContractor
SchoolUCSF Chancellor/EVC/FAS
DepartmentStudent Academic Affairs
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    Collapse Research 
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    High resolution imaging of developmentally regulated epigenetic alterations
    NIH/NIGMS F32GM099389Apr 1, 2012 - Mar 31, 2014
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Goodrich L, Panning B, Leung K. Activators and repressors: A balancing act for X-inactivation. Semin Cell Dev Biol. 2016 Aug; 56:3-8. PMID: 27223409.
      View in: PubMed
    2. Smith EA, McDermott G, Do M, Leung K, Panning B, Le Gros MA, Larabell CA. Quantitatively imaging chromosomes by correlated cryo-fluorescence and soft x-ray tomographies. Biophys J. 2014 Oct 21; 107(8):1988-96. PMID: 25418180; PMCID: PMC4213715.
    3. Leung K, Panning B. X-inactivation: Xist RNA uses chromosome contacts to coat the X. Curr Biol. 2014 Jan 20; 24(2):R80-2. PMID: 24456982; PMCID: PMC4465072.
    4. Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S. Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell. 2012 Jul 6; 11(1):91-9. PMID: 22770243; PMCID: PMC3396435.
    5. Singleton MK, Gonzales ML, Leung K, Yasui DH, Schroeder DI, Dunaway K, LaSalle JM. MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. Neurobiol Dis. 2011 Jul; 43(1):190-200. PMID: 21420494; PMCID: PMC3096744.
    6. Leung K, Chamberlain SJ, Lalande M, LaSalle JM. Neuronal chromatin dynamics of imprinting in development and disease. J Cell Biochem. 2011 Feb; 112(2):365-73. PMID: 21268055; PMCID: PMC3090268.
    7. Leung K, Vallero RO, DuBose AJ, Resnick JL, LaSalle JM. Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size. Hum Mol Genet. 2009 Nov 15; 18(22):4227-38. PMID: 19656775; PMCID: PMC2766290.
    8. Wang NJ, Parokonny AS, Thatcher KN, Driscoll J, Malone BM, Dorrani N, Sigman M, LaSalle JM, Schanen NC. Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15. BMC Genet. 2008; 9:2. PMID: 18177502; PMCID: PMC2249594.
    9. Yasui DH, Peddada S, Bieda MC, Vallero RO, Hogart A, Nagarajan RP, Thatcher KN, Farnham PJ, Lasalle JM. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc Natl Acad Sci U S A. 2007 Dec 4; 104(49):19416-21. PMID: 18042715; PMCID: PMC2148304.
    10. Delgado IJ, Kim DS, Thatcher KN, LaSalle JM, Van den Veyver IB. Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients. BMC Med Genet. 2006; 7:61. PMID: 16859563; PMCID: PMC1569822.
    11. Thatcher KN, LaSalle JM. Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2. Epigenetics. 2006 Jan-Mar; 1(1):24-31. PMID: 17464364; PMCID: PMC1857283.
    12. Thatcher KN, Peddada S, Yasui DH, Lasalle JM. Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples. Hum Mol Genet. 2005 Mar 15; 14(6):785-97. PMID: 15689352.
      View in: PubMed
    13. LaSalle JM, Hogart A, Thatcher KN. Rett syndrome: a Rosetta stone for understanding the molecular pathogenesis of autism. Int Rev Neurobiol. 2005; 71:131-65. PMID: 16512349.
      View in: PubMed
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