Kathleen Molnar, PhD

TitleViewPoint Ther. Res. Scientist
InstitutionUniversity of California San Francisco
DepartmentPharmaceutical Chemistry
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Reed NI, Tang YZ, McIntosh J, Wu Y, Molnar K, Civitavecchia A, Sheppard D, DeGrado WF, Jo H. Exploring N-Arylsulfonyl-l-proline Scaffold as a Platform for Potent and Selective avß1 Integrin Inhibitors. ACS Med Chem Lett. 2016 Oct 13; 7(10):902-907. PMID: 27774126.
      View in: PubMed
    2. Bhate MP, Molnar K, Goulian M, DeGrado WF. Signal transduction in histidine kinases: insights from new structures. Structure. 2015 Jun 02; 23(6):981-94. PMID: 25982528; PMCID: PMC4456306.
    3. Molnar K, Bonomi M, Pellarin R, Clinthorne GD, Gonzalez G, Goldberg SD, Goulian M, Sali A, DeGrado WF. Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ. Structure. 2014 Sep 02; 22(9):1239-1251. PMID: 25087511; PMCID: PMC4322757.
    4. Metcalf DG, Moore DT, Wu Y, Kielec JM, Molnar K, Valentine KG, Wand AJ, Bennett JS, DeGrado WF. NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22481-6. PMID: 21156831; PMCID: PMC3012518.
    5. Kong L, Huang CC, Coales SJ, Molnar K, Skinner J, Hamuro Y, Kwong PD. Local conformational stability of HIV-1 gp120 in unliganded and CD4-bound states as defined by amide hydrogen/deuterium exchange. J Virol. 2010 Oct; 84(19):10311-21. PMID: 20660185; PMCID: PMC2937775.
    6. Molnar K, Karabacak NM, Johnson JL, Wang Q, Tiwari A, Hayward LJ, Coales SJ, Hamuro Y, Agar JN. A common property of amyotrophic lateral sclerosis-associated variants: destabilization of the copper/zinc superoxide dismutase electrostatic loop. J Biol Chem. 2009 Nov 06; 284(45):30965-73. PMID: 19635794; PMCID: PMC2781497.
    7. Luo L, Carson JD, Molnar K, Tuske SJ, Coales SJ, Hamuro Y, Sung CM, Sudakin V, Auger KR, Dhanak D, Jackson JR, Huang PS, Tummino PJ, Copeland RA. Conformation-dependent ligand regulation of ATP hydrolysis by human KSP: activation of basal hydrolysis and inhibition of microtubule-stimulated hydrolysis by a single, small molecule modulator. J Am Chem Soc. 2008 Jun 18; 130(24):7584-91. PMID: 18491908.
      View in: PubMed
    8. Schuster MC, Ricklin D, Papp K, Molnar K, Coales SJ, Hamuro Y, Sfyroera G, Chen H, Winters MS, Lambris JD. Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry. Mol Immunol. 2008 Jun; 45(11):3142-51. PMID: 18456336; PMCID: PMC2453784.
    9. Hamuro Y, Coales SJ, Molnar K, Tuske SJ, Morrow JA. Specificity of immobilized porcine pepsin in H/D exchange compatible conditions. Rapid Commun Mass Spectrom. 2008 Apr; 22(7):1041-6. PMID: 18327892.
      View in: PubMed
    10. Hamuro Y, Molnar K, Coales SJ, OuYang B, Simorellis AK, Pochapsky TC. Hydrogen-deuterium exchange mass spectrometry for investigation of backbone dynamics of oxidized and reduced cytochrome P450cam. J Inorg Biochem. 2008 Feb; 102(2):364-70. PMID: 18023482; PMCID: PMC2279175.
    11. Hamuro Y, Coales SJ, Morrow JA, Molnar K, Tuske SJ, Southern MR, Griffin PR. Hydrogen/deuterium-exchange (H/D-Ex) of PPARgamma LBD in the presence of various modulators. Protein Sci. 2006 Aug; 15(8):1883-92. PMID: 16823031; PMCID: PMC2242592.
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