Kathy Franks-Skiba, MS

SchoolUCSF School of Medicine
DepartmentCellular Molecular Pharmacology
Address1700 4th Street
San Francisco CA 94158
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    1. Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ. Vif hijacks CBF-ß to degrade APOBEC3G and promote HIV-1 infection. Nature. 2011 Dec 21; 481(7381):371-5. PMID: 22190037; PMCID: PMC3310910.
    2. Purcell TJ, Naber N, Franks-Skiba K, Dunn AR, Eldred CC, Berger CL, Málnási-Csizmadia A, Spudich JA, Swank DM, Pate E, Cooke R. Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency. J Mol Biol. 2011 Mar 18; 407(1):79-91. PMID: 21185304; PMCID: PMC3347976.
    3. Stewart M, Franks-Skiba K, Cooke R. Myosin regulatory light chain phosphorylation inhibits shortening velocities of skeletal muscle fibers in the presence of the myosin inhibitor blebbistatin. J Muscle Res Cell Motil. 2009; 30(1-2):17-27. PMID: 19125340.
      View in: PubMed
    4. Chinn MK, Myburgh KH, Pham T, Franks-Skiba K, Cooke R. The effect of polyethylene glycol on the mechanics and ATPase activity of active muscle fibers. Biophys J. 2000 Feb; 78(2):927-39. PMID: 10653805; PMCID: PMC1300695.
    5. Highsmith S, Duignan K, Franks-Skiba K, Polosukhina K, Cooke R. Reversible inactivation of myosin subfragment 1 activity by mechanical immobilization. Biophys J. 1998 Mar; 74(3):1465-72. PMID: 9512042; PMCID: PMC1299492.
    6. Pate E, Franks-Skiba K, Cooke R. Depletion of phosphate in active muscle fibers probes actomyosin states within the powerstroke. Biophys J. 1998 Jan; 74(1):369-80. PMID: 9449337; PMCID: PMC1299389.
    7. Pate E, Naber N, Matuska M, Franks-Skiba K, Cooke R. Opening of the myosin nucleotide triphosphate binding domain during the ATPase cycle. Biochemistry. 1997 Oct 07; 36(40):12155-66. PMID: 9315852.
      View in: PubMed
    8. Myburgh KH, Franks-Skiba K, Cooke R. Nucleotide turnover rate measured in fully relaxed rabbit skeletal muscle myofibrils. J Gen Physiol. 1995 Nov; 106(5):957-73. PMID: 8648299; PMCID: PMC2229283.
    9. Pate E, Bhimani M, Franks-Skiba K, Cooke R. Reduced effect of pH on skinned rabbit psoas muscle mechanics at high temperatures: implications for fatigue. J Physiol. 1995 Aug 01; 486 ( Pt 3):689-94. PMID: 7473229; PMCID: PMC1156556.
    10. Franks-Skiba K, Cooke R. The conformation of the active site of myosin probed using mant-nucleotides. Biophys J. 1995 Apr; 68(4 Suppl):142S-147S; discussion 147S-149S. PMID: 7787057; PMCID: PMC1281897.
    11. Franks-Skiba K, Hwang T, Cooke R. Quenching of fluorescent nucleotides bound to myosin: a probe of the active-site conformation. Biochemistry. 1994 Oct 25; 33(42):12720-8. PMID: 7918498.
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    12. Pate E, Franks-Skiba K, White H, Cooke R. The use of differing nucleotides to investigate cross-bridge kinetics. J Biol Chem. 1993 May 15; 268(14):10046-53. PMID: 8486676.
      View in: PubMed
    13. Pate E, Lin M, Franks-Skiba K, Cooke R. Contraction of glycerinated rabbit slow-twitch muscle fibers as a function of MgATP concentration. Am J Physiol. 1992 Apr; 262(4 Pt 1):C1039-46. PMID: 1566809.
      View in: PubMed
    14. Pate E, Nakamaye KL, Franks-Skiba K, Yount RG, Cooke R. Mechanics of glycerinated muscle fibers using nonnucleoside triphosphate substrates. Biophys J. 1991 Mar; 59(3):598-605. PMID: 2049521; PMCID: PMC1281224.
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