Katja Brueckner | UCSF Profiles

Katja Brueckner, PhD

Title	Associate Professor
Institution	University of California San Francisco
Department	Cell and Tissue Biology
Address	35 Medical Center Way San Francisco CA 94143
Phone	415-476-3827
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Biography

Education and Training

Harvard Medical School, Boston, MA	Postdoc	2006	Genetics
European Molecular Biology Laboratory (EMBL) Heidelberg, Germany	Postdoc	2000	Developmental Biology
European Molecular Biology Laboratory (EMBL) and University of Heidelberg, Germany	Ph.D.	1999	Cell Signaling
Max-Planck-Institute for Biochemistry and Ludwig-Maximilians-University, Munich, Germany	Dipl. Biol. (Masters)	1994	Molecular Biology

Overview

Katja Brueckner received her PhD. in biology and cell signalling from the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany. She performed her postdoctoral studies at the EMBL and Harvard Medical School. Katja was a Howard Hughes Medical Institute Associate, long-term post-doctoral fellow of the European Molecular Biology Organization (EMBO) and Human Frontier Science Program (HFSP), and Special Fellow of the Leukemia & Lymphoma Society (LLS). For her post-doctoral studies, the LLS awarded Katja with the Brian P. ODell Memorial Research Award. Since joining the faculty of UCSF in late 2006, Katja has received a Hellman Family Scholar Award, an American Cancer Society Research Scholar Award, an American Heart Association career development award, and she is funded by research grants from the National Science Foundation and the National Institutes of Health.

Research

Research Activities and Funding

Regulation of cell signaling and developmental adaptation by sensory stimulation
NIH R01GM112083Sep 1, 2014 - Aug 31, 2019
Role: Principal Investigator

Mechanisms of hematopoietic regulation by the nervous system
NIH R56HL118726Sep 1, 2014 - Aug 31, 2015
Role: Principal Investigator

ORNG Applications

Websites

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.

List All | Timeline

Petraki, S., Alexander, B., Brückner, K..Assaying blood cell populations of the Drosophila melanogaster larva. Journal of Visualized Experiments (JoVE). 2015; (In press).
Gold KS, Brückner K. Drosophila as a model for the two myeloid blood cell systems in vertebrates. Exp Hematol. 2014 Aug; 42(8):717-27. PMID: 24946019; PMCID: PMC5013032.

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Xu J, Wang AH, Oses-Prieto J, Makhijani K, Katsuno Y, Pei M, Yan L, Zheng YG, Burlingame A, Brückner K, Derynck R. Arginine Methylation Initiates BMP-Induced Smad Signaling. Mol Cell. 2013 Jul 11; 51(1):5-19. PMID: 23747011; PMCID: PMC3951972.

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Makhijani K, Brückner K. Of blood cells and the nervous system: hematopoiesis in the Drosophila larva. Fly (Austin). 2012 Oct-Dec; 6(4):254-60. PMID: 23022764; PMCID: PMC3519660.

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Kelsey EM, Luo X, Brückner K, Jasper H. Schnurri regulates hemocyte function to promote tissue recovery after DNA damage. J Cell Sci. 2012 Mar 15; 125(Pt 6):1393-400. PMID: 22275438; PMCID: PMC3336376.

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Brückner K. Blood cells need glia, too: a new role for the nervous system in the bone marrow niche. Cell Stem Cell. 2011 Dec 02; 9(6):493-5. PMID: 22136920.

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Makhijani K, Alexander B, Tanaka T, Rulifson E, Brückner K. The peripheral nervous system supports blood cell homing and survival in the Drosophila larva. Development. 2011 Dec; 138(24):5379-91. PMID: 22071105; PMCID: PMC3222213.

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Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. PLoS Genet. 2010 Jun 17; 6(6):e1000990. PMID: 20585550; PMCID: PMC2887466.

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Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N. The PDGF/VEGF receptor controls blood cell survival in Drosophila. Dev Cell. 2004 Jul; 7(1):73-84. PMID: 15239955.

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Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R. The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep. 2001 May; 2(5):446-52. PMID: 11375938; PMCID: PMC1083888.

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Brückner K, Perez L, Clausen H, Cohen S. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature. 2000 Jul 27; 406(6794):411-5. PMID: 10935637.

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Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 1999 Mar; 22(3):511-24. PMID: 10197531.

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Brückner K, Klein R. Signaling by Eph receptors and their ephrin ligands. Curr Opin Neurobiol. 1998 Jun; 8(3):375-82. PMID: 9687349.

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Brückner K, Pasquale EB, Klein R. Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Science. 1997 Mar 14; 275(5306):1640-3. PMID: 9054357.

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Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol Cell Neurosci. 1996; 8(2-3):199-209. PMID: 8918835.

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