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Katja Brueckner, PhD

TitleAssociate Professor
SchoolUCSF School of Dentistry
DepartmentCell and Tissue Biology
Address35 Medical Center Way
San Francisco CA 94143
Phone415-476-3827
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    Collapse Biography 
    Collapse Education and Training
    Harvard Medical School, Boston, MAPostdoc2006Genetics
    European Molecular Biology Laboratory (EMBL) Heidelberg, GermanyPostdoc2000Developmental Biology
    European Molecular Biology Laboratory (EMBL) and University of Heidelberg, GermanyPh.D.1999Cell Signaling
    Max-Planck-Institute for Biochemistry and Ludwig-Maximilians-University, Munich, Germany Dipl. Biol. (Masters)1994Molecular Biology

    Collapse Overview 
    Collapse Overview
    Katja Brueckner received her PhD. in biology and cell signalling from the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany. She performed her postdoctoral studies at the EMBL and Harvard Medical School. Katja was a Howard Hughes Medical Institute Associate, long-term post-doctoral fellow of the European Molecular Biology Organization (EMBO) and Human Frontier Science Program (HFSP), and Special Fellow of the Leukemia & Lymphoma Society (LLS). For her post-doctoral studies, the LLS awarded Katja with the Brian P. ODell Memorial Research Award. Since joining the faculty of UCSF in late 2006, Katja has received a Hellman Family Scholar Award, an American Cancer Society Research Scholar Award, an American Heart Association career development award, and she is funded by research grants from the National Science Foundation and the National Institutes of Health.


    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of cell signaling and developmental adaptation by sensory stimulation
    NIH R01GM112083Sep 1, 2014 - Aug 31, 2019
    Role: Principal Investigator
    Mechanisms of hematopoietic regulation by the nervous system
    NIH R56HL118726Sep 1, 2014 - Aug 31, 2015
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Petraki, S., Alexander, B., Brückner, K.. Assaying blood cell populations of the Drosophila melanogaster larva. Journal of Visualized Experiments (JoVE). 2015; (In press).
    2. Gold KS, Brückner K. Drosophila as a model for the two myeloid blood cell systems in vertebrates. Exp Hematol. 2014 Aug; 42(8):717-27. PMID: 24946019.
      View in: PubMed
    3. Xu J, Wang AH, Oses-Prieto J, Makhijani K, Katsuno Y, Pei M, Yan L, Zheng YG, Burlingame A, Brückner K, Derynck R. Arginine Methylation Initiates BMP-Induced Smad Signaling. Mol Cell. 2013 Jul 11; 51(1):5-19. PMID: 23747011; PMCID: PMC3951972.
      View in: PubMed, PubMed Central
    4. Makhijani K, Brückner K. Of blood cells and the nervous system: hematopoiesis in the Drosophila larva. Fly (Austin). 2012 Oct-Dec; 6(4):254-60. PMID: 23022764; PMCID: PMC3519660.
      View in: PubMed, PubMed Central
    5. Kelsey EM, Luo X, Brückner K, Jasper H. Schnurri regulates hemocyte function to promote tissue recovery after DNA damage. J Cell Sci. 2012 Mar 15; 125(Pt 6):1393-400. PMID: 22275438; PMCID: PMC3336376.
      View in: PubMed, PubMed Central
    6. Brückner K. Blood cells need glia, too: a new role for the nervous system in the bone marrow niche. Cell Stem Cell. 2011 Dec 2; 9(6):493-5. PMID: 22136920.
      View in: PubMed
    7. Makhijani K, Alexander B, Tanaka T, Rulifson E, Brückner K. The peripheral nervous system supports blood cell homing and survival in the Drosophila larva. Development. 2011 Dec; 138(24):5379-91. PMID: 22071105; PMCID: PMC3222213.
      View in: PubMed, PubMed Central
    8. Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. PLoS Genet. 2010 Jun; 6(6):e1000990. PMID: 20585550; PMCID: PMC2887466.
      View in: PubMed, PubMed Central
    9. Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N. The PDGF/VEGF receptor controls blood cell survival in Drosophila. Dev Cell. 2004 Jul; 7(1):73-84. PMID: 15239955.
      View in: PubMed
    10. Labrador JP, Azcoitia V, Tuckermann J, Lin C, Olaso E, Mañes S, Brückner K, Goergen JL, Lemke G, Yancopoulos G, Angel P, Martínez C, Klein R. The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep. 2001 May; 2(5):446-52. PMID: 11375938; PMCID: PMC1083888.
      View in: PubMed, PubMed Central
    11. Brückner K, Perez L, Clausen H, Cohen S. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature. 2000 Jul 27; 406(6794):411-5. PMID: 10935637.
      View in: PubMed
    12. Brückner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 1999 Mar; 22(3):511-24. PMID: 10197531.
      View in: PubMed
    13. Brückner K, Klein R. Signaling by Eph receptors and their ephrin ligands. Curr Opin Neurobiol. 1998 Jun; 8(3):375-82. PMID: 9687349.
      View in: PubMed
    14. Brückner K, Pasquale EB, Klein R. Tyrosine phosphorylation of transmembrane ligands for Eph receptors. Science. 1997 Mar 14; 275(5306):1640-3. PMID: 9054357.
      View in: PubMed
    15. Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol Cell Neurosci. 1996; 8(2-3):199-209. PMID: 8918835.
      View in: PubMed
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