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From exosomes to mitochondria and myocardial infarction: Molecular insight and therapeutic challenge. Pharmacol Res. 2024 Nov; 209:107468.
Liu C, Zhang D, Long K, Qi W, Pang L, Li J, Cheng KK, Cai Y. PMID: 39426469.
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1 Fields:
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HumansAnimalsCells
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MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice. Nat Commun. 2024 Oct 04; 15(1):8624.
Wu KK, Xu X, Wu M, Li X, Hoque M, Li GHY, Lian Q, Long K, Zhou T, Piao H, Xu A, Hui HX, Cheng KK. PMID: 39366973; PMCID: PMC11452520.
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1 Fields:
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HumansAnimalsCells
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Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains. ACS Med Chem Lett. 2024 Oct 10; 15(10):1764-1770.
Klope MT, Tapia Cardona JA, Chen J, Gonciarz RL, Cheng K, Jaishankar P, Kim J, Legac J, Rosenthal PJ, Renslo AR. PMID: 39411530; PMCID: PMC11472393.
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Reactivity-Tunable Fluorescent Platform for Selective and Biocompatible Modification of Cysteine or Lysine. Adv Sci (Weinh). 2024 Aug; 11(31):e2402838.
Ren X, Li H, Peng H, Yang Y, Su H, Huang C, Wang X, Zhang J, Liu Z, Wei W, Cheng K, Zhu T, Lu Z, Li Z, Zhao Q, Tang BZ, Yao SQ, Song X, Sun H. PMID: 38896788; PMCID: PMC11336953.
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1 Fields:
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HumansCells
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TransPTM: a transformer-based model for non-histone acetylation site prediction. Brief Bioinform. 2024 Mar 27; 25(3).
Meng L, Chen X, Cheng K, Chen N, Zheng Z, Wang F, Sun H, Wong KC. PMID: 38725156; PMCID: PMC11082075.
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2 Fields:
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HumansCells
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Identification of SIRT3 as an eraser of H4K16la. iScience. 2023 Oct 20; 26(10):107757.
Fan Z, Liu Z, Zhang N, Wei W, Cheng K, Sun H, Hao Q. PMID: 37720100; PMCID: PMC10504495.
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4
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An End-to-End Dynamic Posture Perception Method for Soft Actuators Based on Distributed Thin Flexible Porous Piezoresistive Sensors. Sensors (Basel). 2023 Jul 06; 23(13).
Shu J, Wang J, Cheng KC, Yeung LF, Li Z, Tong RK. PMID: 37448037; PMCID: PMC10347248.
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De Novo Designed Self-Assembling Rhodamine Probe for Real-Time, Long-Term and Quantitative Live-Cell Nanoscopy. ACS Nano. 2023 02 28; 17(4):3632-3644.
Zhang J, Shi H, Huang C, Mei L, Guo Q, Cheng K, Wu P, Su D, Chen Q, Gan S, Wing Chan CK, Shi J, Chen JL, Jonathan Choi CH, Yao SQ, Chen XK, Tang BZ, He J, Sun H. PMID: 36744992.
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Cells
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Universal Strategy to Develop Fluorogenic Probes for Lysine Deacylase/Demethylase Activity and Application in Discriminating Demethylation States. ACS Sens. 2023 01 27; 8(1):28-39.
Wei W, Zhang J, Xu Z, Liu Z, Huang C, Cheng K, Meng L, Matsuda Y, Hao Q, Zhang H, Sun H. PMID: 36602906.
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1 Fields:
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Cells
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Self-assembled nano-photosensitizer for targeted, activatable, and biosafe cancer phototheranostics. Biomaterials. 2022 12; 291:121916.
Cheng K, Qi J, Zhang J, Li H, Ren X, Wei W, Meng L, Li J, Li Q, Zhang H, Deng W, Sun H, Mei L. PMID: 36410110.
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6 Fields:
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Humans
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Developing Isoxazole as a Native Photo-Cross-Linker for Photoaffinity Labeling and Chemoproteomics. Angew Chem Int Ed Engl. 2022 11 21; 61(47):e202209947.
Cheng K, Qi J, Ren X, Zhang J, Li H, Xiao H, Wang R, Liu Z, Meng L, Ma N, Sun H. PMID: 36151600.
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3 Fields:
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Dietary exposure to polystyrene nanoplastics impairs fasting-induced lipolysis in adipose tissue from high-fat diet fed mice. J Hazard Mater. 2022 10 15; 440:129698.
Shiu HT, Pan X, Liu Q, Long K, Cheng KKY, Ko BC, Fang JK, Zhu Y. PMID: 35952428.
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7 Fields:
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AnimalsCellsPHPublic Health
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Mini-review: Recent advances in post-translational modification site prediction based on deep learning. Comput Struct Biotechnol J. 2022; 20:3522-3532.
Meng L, Chan WS, Huang L, Liu L, Chen X, Zhang W, Wang F, Cheng K, Sun H, Wong KC. PMID: 35860402; PMCID: PMC9284371.
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11
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Robust Artificial Interphases Constructed by a Versatile Protein-Based Binder for High-Voltage Na-Ion Battery Cathodes. Adv Mater. 2022 Jul; 34(29):e2202624.
Li H, Guan C, Zhang J, Cheng K, Chen Q, He L, Ge X, Lai Y, Sun H, Zhang Z. PMID: 35561414.
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3 Fields:
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YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells. Diabetes. 2022 05 01; 71(5):961-977.
Liu D, Yang KY, Chan VW, Ye W, Chong CCN, Wang CC, Wang H, Zhou B, Cheng KKY, Lui KO. PMID: 35113157; PMCID: PMC9044128.
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8 Fields:
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AnimalsCells
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Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77-FGF21 pathway. Hepatology. 2023 01 01; 77(1):213-229.
Ahuja P, Bi X, Ng CF, Tse MCL, Hang M, Pang BPS, Iu ECY, Chan WS, Ooi XC, Sun A, Herlea-Pana O, Liu Z, Yang X, Jiao B, Ma X, Wu KKL, Lee LTO, Cheng KKY, Lee CW, Chan CB. PMID: 35363898.
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PubMed Mentions:
8 Fields:
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Animals
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A new role of the early endosome in restricting NLRP3 inflammasome via mitophagy. Autophagy. 2022 06; 18(6):1475-1477.
Wu KKL, Cheng KKY. PMID: 35196181; PMCID: PMC9225602.
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6 Fields:
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Cells
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The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages. Nat Commun. 2021 11 17; 12(1):6637.
Wu KKL, Long K, Lin H, Siu PMF, Hoo RLC, Ye D, Xu A, Cheng KKY. PMID: 34789781; PMCID: PMC8599493.
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33 Fields:
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AnimalsCells
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Low-Density Lipoprotein Receptor-Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes. Adv Sci (Weinh). 2021 08; 8(16):e2004993.
Chow HM, Sun JK, Hart RP, Cheng KK, Hung CHL, Lau TM, Kwan KM. PMID: 34180138; PMCID: PMC8373092.
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7 Fields:
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HumansCells
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Deficiency of telomere-associated repressor activator protein 1 precipitates cardiac aging in mice via p53/PPARα signaling. Theranostics. 2021; 11(10):4710-4727.
Cai Y, Liu H, Song E, Wang L, Xu J, He Y, Zhang D, Zhang L, Cheng KK, Jin L, Wu M, Liu S, Qi D, Zhang L, Lopaschuk GD, Wang S, Xu A, Xia Z. PMID: 33754023; PMCID: PMC7978321.
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14 Fields:
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AnimalsCells
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Heterobifunctional PEG-grafted black phosphorus quantum dots: "Three-in-One" nano-platforms for mitochondria-targeted photothermal cancer therapy. Asian J Pharm Sci. 2021 Mar; 16(2):222-235.
Qi J, Xiong Y, Cheng K, Huang Q, Cao J, He F, Mei L, Liu G, Deng W. PMID: 33995616; PMCID: PMC8105514.
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11
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A pyrene-based ratiometric fluorescent probe with a large Stokes shift for selective detection of hydrogen peroxide in living cells. J Pharm Anal. 2020 Oct; 10(5):490-497.
Chen Q, Cheng K, Wang W, Yang L, Xie Y, Feng L, Zhang J, Zhang H, Sun H. PMID: 33133733; PMCID: PMC7591780.
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4
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Potential Involvement of Adiponectin Signaling in Regulating Physical Exercise-Elicited Hippocampal Neurogenesis and Dendritic Morphology in Stressed Mice. Front Cell Neurosci. 2020; 14:189.
Wang P, Liang Y, Chen K, Yau SY, Sun X, Cheng KK, Xu A, So KF, Li A. PMID: 32774242; PMCID: PMC7381385.
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11
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Controllable Cleavage of C-N Bond-Based Fluorescent and Photoacoustic Dual-Modal Probes for the Detection of H2S in Living Mice. ACS Appl Bio Mater. 2021 03 15; 4(3):2020-2025.
Zhang J, Wen G, Wang W, Cheng K, Guo Q, Tian S, Liu C, Hu H, Zhang Y, Zhang H, Wang L, Sun H. PMID: 35014327.
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10 Fields:
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AnimalsCells
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Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors. ACS Chem Biol. 2019 12 20; 14(12):2546-2552.
Ma N, Zhang ZM, Lee JS, Cheng K, Lin L, Zhang DM, Hao P, Ding K, Ye WC, Li Z. PMID: 31742988.
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7 Fields:
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HumansCells
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An ultra-sensitive ratiometric fluorescent probe for hypochlorous acid detection by the synergistic effect of AIE and TBET and its application of detecting exogenous/endogenous HOCl in living cells. J Mater Chem B. 2019 09 07; 7(33):5125-5131.
Duan Q, Zheng G, Li Z, Cheng K, Zhang J, Yang L, Jiang Y, Zhang H, He J, Sun H. PMID: 31363729.
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4 Fields:
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AnimalsCells
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Yoga training modulates adipokines in adults with high-normal blood pressure and metabolic syndrome. Scand J Med Sci Sports. 2018 Mar; 28(3):1130-1138.
Supriya R, Yu AP, Lee PH, Lai CW, Cheng KK, Yau SY, Chan LW, Yung BY, Siu PM. PMID: 29205515.
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10 Fields:
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Humans
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Tetrazole-Based Probes for Integrated Phenotypic Screening, Affinity-Based Proteome Profiling, and Sensitive Detection of a Cancer Biomarker. Angew Chem Int Ed Engl. 2017 11 20; 56(47):15044-15048.
Cheng K, Lee JS, Hao P, Yao SQ, Ding K, Li Z. PMID: 28967196.
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30 Fields:
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HumansCells
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APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes. Diabetologia. 2017 03; 60(3):464-474.
Jiang X, Zhou Y, Wu KK, Chen Z, Xu A, Cheng KK. PMID: 28011992.
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PubMed Mentions:
8 Fields:
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HumansAnimalsCells
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Chronic adiponectin deficiency leads to Alzheimer's disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice. Mol Neurodegener. 2016 11 25; 11(1):71.
Ng RC, Cheng OY, Jian M, Kwan JS, Ho PW, Cheng KK, Yeung PK, Zhou LL, Hoo RL, Chung SK, Xu A, Lam KS, Chan KH. PMID: 27884163; PMCID: PMC5123368.
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73 Fields:
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Animals
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Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity. PLoS One. 2012; 7(12):e52354.
Chan KH, Lam KS, Cheng OY, Kwan JS, Ho PW, Cheng KK, Chung SK, Ho JW, Guo VY, Xu A. PMID: 23300647; PMCID: PMC3531475.
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PubMed Mentions:
72 Fields:
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HumansAnimalsCells