Keelan Guiley, PhD

Title(s)Postdoctoral Research Fellow, Howard Hughes Medical Instit
SchoolSchool of Medicine
AddressLocation Required
Varies CA 00000
Phone--
ORCID ORCID Icon0000-0002-8149-4262 Additional info
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    Collapse Research 
    Collapse Research Activities and Funding
    Cell cycle control through DREAM and MMB complexes
    NIH F31CA206244Apr 1, 2016 - Mar 31, 2018
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S). Nat Chem Biol. 2022 Jul 21. Zhang Z, Guiley KZ, Shokat KM. PMID: 35864332.
      View in: PubMed   Mentions:    Fields:    
    2. The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun. 2022 01 26; 13(1):526. Asthana A, Ramanan P, Hirschi A, Guiley KZ, Wijeratne TU, Shelansky R, Doody MJ, Narasimhan H, Boeger H, Tripathi S, Müller GA, Rubin SM. PMID: 35082292; PMCID: PMC8792015.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    3. A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes. Biol Open. 2020 05 07; 9(5). Vorster PJ, Goetsch P, Wijeratne TU, Guiley KZ, Andrejka L, Tripathi S, Larson BJ, Rubin SM, Strome S, Lipsick JS. PMID: 32295830; PMCID: PMC7225089.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition. Science. 2019 12 13; 366(6471). Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM. PMID: 31831640; PMCID: PMC7592119.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    5. Structural mechanism of Myb-MuvB assembly. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):10016-10021. Guiley KZ, Iness AN, Saini S, Tripathi S, Lipsick JS, Litovchick L, Rubin SM. PMID: 30224471; PMCID: PMC6176624.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    6. The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb. Oncogene. 2019 02; 38(7):1080-1092. Iness AN, Felthousen J, Ananthapadmanabhan V, Sesay F, Saini S, Guiley KZ, Rubin SM, Dozmorov M, Litovchick L. PMID: 30206359; PMCID: PMC6377300.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    7. Structural mechanisms of DREAM complex assembly and regulation. Genes Dev. 2015 May 01; 29(9):961-74. Guiley KZ, Liban TJ, Felthousen JG, Ramanan P, Litovchick L, Rubin SM. PMID: 25917549; PMCID: PMC4421984.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    8. The molecular architecture of human Dicer. Nat Struct Mol Biol. 2012 Mar 18; 19(4):436-40. Lau PW, Guiley KZ, De N, Potter CS, Carragher B, MacRae IJ. PMID: 22426548; PMCID: PMC3319852.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    9. Single-pot enzymatic synthesis of Dicer-substrate siRNAs. Nucleic Acids Res. 2012 Mar; 40(5):e40. Guiley KZ, Pratt AJ, MacRae IJ. PMID: 22189103; PMCID: PMC3299999.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
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