Kevin Leu, MD, PhD

Title(s)Resident, Radiology
SchoolSchool of Medicine
Address185 Berry Street Bldg B, #B20
San Francisco CA 94158
Phone--
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spinal Cord Perfusion MR Imaging Implicates Both Ischemia and Hypoxia in the Pathogenesis of Cervical Spondylosis. World Neurosurg. 2019 Aug; 128:e773-e781. Ellingson BM, Woodworth DC, Leu K, Salamon N, Holly LT. PMID: 31077900; PMCID: PMC8805085.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    2. Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry. Sci Rep. 2019 02 26; 9(1):2846. Chakhoyan A, Yao J, Yao J, Leu K, Pope WB, Salamon N, Yong W, Lai A, Nghiemphu PL, Everson RG, Prins RM, Liau LM, Nathanson DA, Cloughesy TF, Ellingson BM. PMID: 30808879; PMCID: PMC6391482.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    3. Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo. Neuro Oncol. 2018 10 09; 20(11):1525-1535. Ellingson BM, Abrey LE, Garcia J, Chinot O, Wick W, Saran F, Nishikawa R, Henriksson R, Mason WP, Harris RJ, Leu K, Woodworth DC, Mehta A, Raymond C, Chakhoyan A, Pope WB, Cloughesy TF. PMID: 29897562; PMCID: PMC6178278.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    4. Volumetric response quantified using T1 subtraction predicts long-term survival benefit from cabozantinib monotherapy in recurrent glioblastoma. Neuro Oncol. 2018 09 03; 20(10):1411-1418. Ellingson BM, Aftab DT, Schwab GM, Hessel C, Harris RJ, Woodworth DC, Leu K, Chakhoyan A, Raymond C, Drappatz J, de Groot J, Prados MD, Reardon DA, Schiff D, Chamberlain M, Mikkelsen T, Desjardins A, Holland J, Ping J, Weitzman R, Wen PY, Cloughesy TF. PMID: 29660005; PMCID: PMC6120362.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    5. Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI). Magn Reson Med. 2018 11; 80(5):1962-1978. Harris RJ, Yao J, Yao J, Chakhoyan A, Raymond C, Leu K, Liau LM, Nghiemphu PL, Lai A, Salamon N, Pope WB, Cloughesy TF, Ellingson BM. PMID: 29626359; PMCID: PMC6107417.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    6. Improved Spatiotemporal Resolution of Dynamic Susceptibility Contrast Perfusion MRI in Brain Tumors Using Simultaneous Multi-Slice Echo-Planar Imaging. AJNR Am J Neuroradiol. 2018 01; 39(1):43-45. Chakhoyan A, Leu K, Pope WB, Cloughesy TF, Ellingson BM. PMID: 29074632; PMCID: PMC5766430.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Diffusion MRI Phenotypes Predict Overall Survival Benefit from Anti-VEGF Monotherapy in Recurrent Glioblastoma: Converging Evidence from Phase II Trials. Clin Cancer Res. 2017 Oct 01; 23(19):5745-5756. Ellingson BM, Gerstner ER, Smits M, Huang RY, Colen R, Abrey LE, Aftab DT, Schwab GM, Hessel C, Harris RJ, Chakhoyan A, Gahrmann R, Pope WB, Leu K, Raymond C, Woodworth DC, de Groot J, Wen PY, Batchelor TT, van den Bent MJ, Cloughesy TF. PMID: 28655794; PMCID: PMC5626594.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    8. Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II-III diffuse gliomas. J Neurooncol. 2017 Aug; 134(1):177-188. Leu K, Ott GA, Lai A, Nghiemphu PL, Pope WB, Yong WH, Liau LM, Cloughesy TF, Ellingson BM. PMID: 28547590; PMCID: PMC7927357.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    9. Evaluation of Encephaloduroarteriosynangiosis Efficacy Using Probabilistic Independent Component Analysis Applied to Dynamic Susceptibility Contrast Perfusion MRI. AJNR Am J Neuroradiol. 2017 Mar; 38(3):507-514. Laiwalla AN, Kurth F, Leu K, Liou R, Pamplona J, Ooi YC, Salamon N, Ellingson BM, Gonzalez NR. PMID: 28104642; PMCID: PMC5832053.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Effects of MRI Protocol Parameters, Preload Injection Dose, Fractionation Strategies, and Leakage Correction Algorithms on the Fidelity of Dynamic-Susceptibility Contrast MRI Estimates of Relative Cerebral Blood Volume in Gliomas. AJNR Am J Neuroradiol. 2017 Mar; 38(3):478-484. Leu K, Boxerman JL, Ellingson BM. PMID: 28034995; PMCID: PMC7959993.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    11. Baseline pretreatment contrast enhancing tumor volume including central necrosis is a prognostic factor in recurrent glioblastoma: evidence from single and multicenter trials. Neuro Oncol. 2017 01; 19(1):89-98. Ellingson BM, Harris RJ, Woodworth DC, Leu K, Zaw O, Mason WP, Sahebjam S, Abrey LE, Aftab DT, Schwab GM, Hessel C, Lai A, Nghiemphu PL, Pope WB, Wen PY, Cloughesy TF. PMID: 27580889; PMCID: PMC5193027.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCTClinical Trials
    12. Improved Leakage Correction for Single-Echo Dynamic Susceptibility Contrast Perfusion MRI Estimates of Relative Cerebral Blood Volume in High-Grade Gliomas by Accounting for Bidirectional Contrast Agent Exchange. AJNR Am J Neuroradiol. 2016 Aug; 37(8):1440-6. Leu K, Boxerman JL, Cloughesy TF, Lai A, Nghiemphu PL, Liau LM, Pope WB, Ellingson BM. PMID: 27079371; PMCID: PMC4983482.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    13. Bidirectional Contrast agent leakage correction of dynamic susceptibility contrast (DSC)-MRI improves cerebral blood volume estimation and survival prediction in recurrent glioblastoma treated with bevacizumab. J Magn Reson Imaging. 2016 11; 44(5):1229-1237. Leu K, Boxerman JL, Lai A, Nghiemphu PL, Pope WB, Cloughesy TF, Ellingson BM. PMID: 26971534.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    14. Association between lesion location and language function in adult glioma using voxel-based lesion-symptom mapping. Neuroimage Clin. 2015; 9:617-24. Banerjee P, Leu K, Harris RJ, Cloughesy TF, Lai A, Nghiemphu PL, Pope WB, Bookheimer SY, Ellingson BM. PMID: 26740915; PMCID: PMC4644251.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    15. Topographical Distribution of Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex. J Child Neurol. 2016 Apr; 31(5):636-45. Ellingson BM, Hirata Y, Yogi A, Karavaeva E, Leu K, Woodworth DC, Harris RJ, Enzmann DR, Wu JY, Mathern GW, Salamon N. PMID: 26472749.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Unique Microstructural Changes in the Brain Associated with Urological Chronic Pelvic Pain Syndrome (UCPPS) Revealed by Diffusion Tensor MRI, Super-Resolution Track Density Imaging, and Statistical Parameter Mapping: A MAPP Network Neuroimaging Study. PLoS One. 2015; 10(10):e0140250. Woodworth D, Mayer E, Leu K, Ashe-McNalley C, Naliboff BD, Labus JS, Tillisch K, Kutch JJ, Farmer MA, Apkarian AV, Johnson KA, Mackey SC, Ness TJ, Landis JR, Deutsch G, Harris RE, Clauw DJ, Mullins C, Ellingson BM, MAPP Research Network. PMID: 26460744; PMCID: PMC4604194.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    17. Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma. Tomography. 2015 Sep; 1(1):37-43. Chang W, Pope WB, Harris RJ, Hardy AJ, Leu K, Mody RR, Nghiemphu PL, Lai A, Cloughesy TF, Ellingson BM. PMID: 26740971; PMCID: PMC4698970.
      View in: PubMed   Mentions: 7     Fields:    
    18. Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas. Mol Imaging Biol. 2015 Jun; 17(3):434-42. Karavaeva E, Harris RJ, Leu K, Shabihkhani M, Yong WH, Pope WB, Lai A, Nghiemphu PL, Liau LM, Chen W, Czernin J, Cloughesy TF, Ellingson BM. PMID: 25465392.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    19. Quantitative multiparametric MRI in uveal melanoma: increased tumor permeability may predict monosomy 3. Neuroradiology. 2015 Aug; 57(8):833-40. Kamrava M, Sepahdari AR, Leu K, Wang PC, Roberts K, Demanes DJ, McCannel T, Ellingson BM. PMID: 26022354.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    20. Hypervascular tumor volume estimated by comparison to a large-scale cerebral blood volume radiographic atlas predicts survival in recurrent glioblastoma treated with bevacizumab. Cancer Imaging. 2014 Nov 14; 14:31. Leu K, Enzmann DR, Woodworth DC, Harris RJ, Tran AN, Lai A, Nghiemphu PL, Pope WB, Cloughesy TF, Ellingson BM. PMID: 25608485; PMCID: PMC4331836.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    21. Using Fractal Geometry and Universal Growth Curves as Diagnostics for Comparing Tumor Vasculature and Metabolic Rate With Healthy Tissue and for Predicting Responses to Drug Therapies. Discrete Continuous Dyn Syst Ser B. 2013 Jun; 18(4). Savage VM, Herman AB, West GB, Leu K. PMID: 24204201; PMCID: PMC3817925.
      View in: PubMed   Mentions: 5  
    22. Imaging biomarkers for antiangiogenic therapy in malignant gliomas. CNS Oncol. 2013 Jan; 2(1):33-47. Leu K, Pope WB, Cloughesy TF, Lai A, Nghiemphu PL, Chen W, Liau LM, Ellingson BM. PMID: 24570837; PMCID: PMC3932329.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences. J Am Chem Soc. 2013 Jan 09; 135(1):354-66. Leu K, Kervio E, Obermayer B, Turk-MacLeod RM, Yuan C, Luevano JM, Chen E, Gerland U, Richert C, Chen IA. PMID: 23259600; PMCID: PMC3557965.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    24. Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences. Nucleic Acids Res. 2012 May; 40(10):4711-22. Derr J, Manapat ML, Rajamani S, Leu K, Xulvi-Brunet R, Joseph I, Nowak MA, Chen IA. PMID: 22319215; PMCID: PMC3378899.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    25. The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA. Nucleic Acids Res. 2011 Oct; 39(18):8135-47. Leu K, Obermayer B, Rajamani S, Gerland U, Chen IA. PMID: 21724606; PMCID: PMC3185426.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    26. Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication. J Am Chem Soc. 2010 Apr 28; 132(16):5880-5. Rajamani S, Ichida JK, Antal T, Treco DA, Leu K, Nowak MA, Szostak JW, Chen IA. PMID: 20359213; PMCID: PMC2857888.
      View in: PubMed   Mentions: 52     Fields:    Translation:Cells
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