Kevin Tharp, PhD

Title(s)Postdoctoral Scholar, Surgery
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE, #550
San Francisco CA 94143
Phone415-476-3826
ORCID ORCID Icon0000-0002-3543-3266 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. SARS-CoV-2 ORF3A interacts with the Clic-like chloride channel-1 (CLCC1) and triggers an unfolded protein response. PeerJ. 2023; 11:e15077. Gruner HN, Zhang Y, Shariati K, Yiv N, Hu Z, Wang Y, Hejtmancik JF, McManus MT, Tharp K, Ku G. PMID: 37033725; PMCID: PMC10078464.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma. Cell Chem Biol. 2022 08 18; 29(8):1288-1302.e7. Ferguson ID, Lin YT, Lam C, Shao H, Tharp KM, Hale M, Kasap C, Mariano MC, Kishishita A, Patiño Escobar B, Mandal K, Steri V, Wang D, Phojanakong P, Tuomivaara ST, Hann B, Driessen C, Van Ness B, Gestwicki JE, Wiita AP. PMID: 35853457; PMCID: PMC9434701.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    3. Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization. Sci Adv. 2021 Oct 29; 7(44):eabj6818. Moehle EA, Higuchi-Sanabria R, Tsui CK, Homentcovschi S, Tharp KM, Zhang H, Chi H, Joe L, de Los Rios Rogers M, Sahay A, Kelet N, Benitez C, Bar-Ziv R, Garcia G, Shen K, Frankino PA, Schinzel RT, Shalem O, Dillin A. PMID: 34714674; PMCID: PMC8555897.
      View in: PubMed   Mentions: 3     Fields:    
    4. Adhesion-mediated mechanosignaling forces mitohormesis. Cell Metab. 2021 07 06; 33(7):1322-1341.e13. Tharp KM, Higuchi-Sanabria R, Timblin GA, Ford B, Garzon-Coral C, Schneider C, Muncie JM, Stashko C, Daniele JR, Moore AS, Frankino PA, Homentcovschi S, Manoli SS, Shao H, Richards AL, Chen KH, Hoeve JT, Ku GM, Hellerstein M, Nomura DK, Saijo K, Gestwicki J, Dunn AR, Krogan NJ, Swaney DL, Dillin A, Weaver VM. PMID: 34019840; PMCID: PMC8266765.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    5. Mitohormesis reprogrammes macrophage metabolism to enforce tolerance. Nat Metab. 2021 05; 3(5):618-635. Timblin GA, Tharp KM, Ford B, Winchester JM, Wang J, Zhu S, Khan RI, Louie SK, Iavarone AT, Ten Hoeve J, Nomura DK, Stahl A, Saijo K. PMID: 34031590; PMCID: PMC8162914.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    6. Transcriptomic analysis reveals that BMP4 sensitizes glioblastoma tumor-initiating cells to mechanical cues. Matrix Biol. 2020 01; 85-86:112-127. Hughes JH, Ewy JM, Chen J, Wong SY, Tharp KM, Stahl A, Kumar S. PMID: 31189077; PMCID: PMC6900459.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    7. Modeling Tissue Polarity in Context. J Mol Biol. 2018 09 28; 430(19):3613-3628. Tharp KM, Weaver VM. PMID: 30055167; PMCID: PMC6150793.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    8. Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues. Cell Metab. 2018 03 06; 27(3):602-615.e4. Tharp KM, Kang MS, Timblin GA, Dempersmier J, Dempsey GE, Zushin PH, Benavides J, Choi C, Li CX, Jha AK, Kajimura S, Healy KE, Sul HS, Saijo K, Kumar S, Stahl A. PMID: 29514068; PMCID: PMC5897043.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    9. The Sense of Smell Impacts Metabolic Health and Obesity. Cell Metab. 2017 Jul 05; 26(1):198-211.e5. Riera CE, Tsaousidou E, Halloran J, Follett P, Hahn O, Pereira MMA, Ruud LE, Alber J, Tharp K, Anderson CM, Brönneke H, Hampel B, Filho CDM, Stahl A, Brüning JC, Dillin A. PMID: 28683287.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    10. WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. Lab Chip. 2017 05 02; 17(9):1645-1654. Loskill P, Sezhian T, Tharp KM, Lee-Montiel FT, Jeeawoody S, Reese WM, Zushin PH, Stahl A, Healy KE. PMID: 28418430; PMCID: PMC5688242.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    11. Amplification of Adipogenic Commitment by VSTM2A. Cell Rep. 2017 01 03; 18(1):93-106. Secco B, Camiré É, Brière MA, Caron A, Billong A, Gélinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad É, Marsolais D, Bossé Y, Birsoy K, Laplante M. PMID: 28052263; PMCID: PMC5551894.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    12. LSD1 Interacts with Zfp516 to Promote UCP1 Transcription and Brown Fat Program. Cell Rep. 2016 06 14; 15(11):2536-49. Sambeat A, Gulyaeva O, Dempersmier J, Tharp KM, Stahl A, Paul SM, Sul HS. PMID: 27264172; PMCID: PMC4916264.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    13. α8β1 integrin regulates nutrient absorption through an Mfge8-PTEN dependent mechanism. Elife. 2016 04 19; 5. Khalifeh-Soltani A, Ha A, Podolsky MJ, McCarthy DA, McKleroy W, Azary S, Sakuma S, Tharp KM, Wu N, Yokosaki Y, Hart D, Stahl A, Atabai K. PMID: 27092791; PMCID: PMC4868538.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    14. Prevention of gallbladder hypomotility via FATP2 inhibition protects from lithogenic diet-induced cholelithiasis. Am J Physiol Gastrointest Liver Physiol. 2016 05 15; 310(10):G855-64. Tharp KM, Khalifeh-Soltani A, Park HM, Yurek DA, Falcon A, Wong L, Feng R, Atabai K, Stahl A. PMID: 27033116; PMCID: PMC4888547.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans. Hepatology. 2016 06; 63(6):1900-13. Li L, Che L, Tharp KM, Park HM, Pilo MG, Cao D, Cigliano A, Latte G, Xu Z, Ribback S, Dombrowski F, Evert M, Gores GJ, Stahl A, Calvisi DF, Chen X. PMID: 26910791; PMCID: PMC4874885.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    16. Matrix metalloproteinase-13 mediated degradation of hyaluronic acid-based matrices orchestrates stem cell engraftment through vascular integration. Biomaterials. 2016 May; 89:136-47. Jha AK, Tharp KM, Browne S, Ye J, Stahl A, Yeghiazarians Y, Healy KE. PMID: 26967648; PMCID: PMC4851169.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    17. Bioengineering Beige Adipose Tissue Therapeutics. Front Endocrinol (Lausanne). 2015; 6:164. Tharp KM, Stahl A. PMID: 26539163; PMCID: PMC4611961.
      View in: PubMed   Mentions: 14     Fields:    
    18. Matrix-Assisted Transplantation of Functional Beige Adipose Tissue. Diabetes. 2015 Nov; 64(11):3713-24. Tharp KM, Jha AK, Kraiczy J, Yesian A, Karateev G, Sinisi R, Dubikovskaya EA, Healy KE, Stahl A. PMID: 26293504; PMCID: PMC4613967.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    19. Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels. Biomaterials. 2015 Apr; 47:1-12. Jha AK, Tharp KM, Ye J, Santiago-Ortiz JL, Jackson WM, Stahl A, Schaffer DV, Yeghiazarians Y, Healy KE. PMID: 25682155; PMCID: PMC4457539.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    20. Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice. PLoS One. 2014; 9(10):e108408. Chudnovskiy R, Thompson A, Tharp K, Hellerstein M, Napoli JL, Stahl A. PMID: 25296035; PMCID: PMC4189915.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    21. Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids. Nat Med. 2014 Feb; 20(2):175-83. Khalifeh-Soltani A, McKleroy W, Sakuma S, Cheung YY, Tharp K, Qiu Y, Turner SM, Chawla A, Stahl A, Atabai K. PMID: 24441829; PMCID: PMC4273653.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    22. Altered norepinephrine content and ventricular function in p75NTR-/- mice after myocardial infarction. Auton Neurosci. 2011 Oct 28; 164(1-2):13-9. Lorentz CU, Woodward WR, Tharp K, Habecker BA. PMID: 21646052; PMCID: PMC3167025.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. Cardiac ischemia-reperfusion regulates sympathetic neuropeptide expression through gp130-dependent and independent mechanisms. Neuropeptides. 2011 Feb; 45(1):33-42. Alston EN, Parrish DC, Hasan W, Tharp K, Pahlmeyer L, Habecker BA. PMID: 21035185; PMCID: PMC3053070.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
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