Keying Zhu, MD, PhD

Title(s)Postdoctoral Scholar, Neurology
SchoolSchool of Medicine
Address35 Medical Center Way, #260
San Francisco CA 94143
ORCID ORCID Icon0000-0001-7500-1532 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Karolinska Institutet, Stockholm, SwedenPostdoc05/2024Neuroimmunology
    Karolinska Institutet, Stockholm, SwedenPhD05/2023Neuroimmunology
    Fudan University, Shanghai, ChinaMSc05/2017Neurobiology
    Guangzhou University of TCM, Guangzhou, ChinaMBBS/MD05/2014Medicine

    Collapse Overview 
    Collapse Overview
    I'm a Swedish Research Council (Vetenskapsrådet) International Postdoc Fellow from Karolinska Institutet, currently conducting postdoctoral research at the Fancy Lab at UCSF. During my PhD, I specialized in microglia biology, and I am now broadening my research to include oligodendrocytes, myelin, and the communication between glial cells.

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns. Nat Nanotechnol. 2024 Sep; 19(9):1366-1374. Wang Y, Baars I, Berzina I, Rocamonde-Lago I, Shen B, Yang Y, Lolaico M, Waldvogel J, Smyrlaki I, Zhu K, Harris RA, Högberg B. PMID: 38951595; PMCID: PMC11405282.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination. Int Immunopharmacol. 2024 Jan 25; 127:111408. Wang DJ, Wang X, Li SL, Zhang TT, Yang YC, Wang YM, Zhao XQ, Li KY, Wang YQ, Li Y, Zhu KY, Wang J. PMID: 38128309.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. CD163+ macrophages monitor enhanced permeability at the blood-dorsal root ganglion barrier. J Exp Med. 2024 Feb 05; 221(2). Lund H, Hunt MA, Kurtovic Z, Sandor K, Kägy PB, Fereydouni N, Julien A, Göritz C, Vazquez-Liebanas E, Andaloussi Mäe M, Jurczak A, Han J, Zhu K, Harris RA, Lampa J, Graversen JH, Etzerodt A, Haglund L, Yaksh TL, Svensson CI. PMID: 38117255; PMCID: PMC10733632.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    4. Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations. JCI Insight. 2023 09 08; 8(17). Zhang J, Koolmeister C, Han J, Filograna R, Hanke L, Àdori M, Sheward DJ, Teifel S, Gopalakrishna S, Shao Q, Liu Y, Zhu K, Harris RA, McInerney G, Murrell B, Aoun M, Bäckdahl L, Holmdahl R, Pekalski M, Wedell A, Engvall M, Wredenberg A, Karlsson Hedestam GB, Castro Dopico X, Rorbach J. PMID: 37681412; PMCID: PMC10544217.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    5. Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination. J Neuroinflammation. 2023 Mar 25; 20(1):83. Wang Y, Sun J, Zhu K, Wang D, Zhao X, Zhang H, Wu S, Wang Y, Wang J. PMID: 36966295; PMCID: PMC10040134.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    6. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function. Acta Pharmacol Sin. 2023 Apr; 44(4):766-779. Sun JX, Zhu KY, Wang YM, Wang DJ, Zhang MZ, Sarlus H, Benito-Cuesta I, Zhao XQ, Zou ZF, Zhong QY, Feng Y, Wu S, Wang YQ, Harris RA, Wang J. PMID: 36229601; PMCID: PMC10043010.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    7. Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation. EMBO Rep. 2022 07 05; 23(7):e54499. Zhu K, Wang Y, Sarlus H, Geng K, Nutma E, Sun J, Kung SY, Bay C, Han J, Min JH, Benito-Cuesta I, Lund H, Amor S, Wang J, Zhang XM, Kutter C, Guerreiro-Cacais AO, Högberg B, Harris RA. PMID: 35593064; PMCID: PMC9253741.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    8. An overlooked subset of Cx3cr1wt/wt microglia in the Cx3cr1CreER-Eyfp/wt mouse has a repopulation advantage over Cx3cr1CreER-Eyfp/wt microglia following microglial depletion. J Neuroinflammation. 2022 Jan 21; 19(1):20. Zhou K, Han J, Lund H, Boggavarapu NR, Lauschke VM, Goto S, Cheng H, Wang Y, Tachi A, Xie C, Zhu K, Sun Y, Osman AM, Liang D, Han W, Gemzell-Danielsson K, Betsholtz C, Zhang XM, Zhu C, Enge M, Joseph B, Harris RA, Blomgren K. PMID: 35062962; PMCID: PMC8783445.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    9. Axonal mitochondria adjust in size depending on g-ratio of surrounding myelin during homeostasis and advanced remyelination. J Neurosci Res. 2021 03; 99(3):793-805. Ineichen BV, Zhu K, Carlström KE. PMID: 33368634; PMCID: PMC7898477.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    10. Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization. Carbohydr Polym. 2021 Feb 15; 254:117291. Rangasami VK, Samanta S, Parihar VS, Asawa K, Zhu K, Varghese OP, Teramura Y, Nilsson B, Hilborn J, Harris RA, Oommen OP. PMID: 33357860.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    11. Sex-Specific Effects of Microglia-Like Cell Engraftment during Experimental Autoimmune Encephalomyelitis. Int J Mol Sci. 2020 Sep 17; 21(18). Han J, Zhu K, Zhou K, Hakim R, Sankavaram SR, Blomgren K, Lund H, Zhang XM, Harris RA. PMID: 32957621; PMCID: PMC7555782.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    12. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis. Nat Commun. 2020 08 13; 11(1):4071. Carlström KE, Zhu K, Ewing E, Krabbendam IE, Harris RA, Falcão AM, Jagodic M, Castelo-Branco G, Piehl F. PMID: 32792491; PMCID: PMC7426940.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    13. Absence of microglia or presence of peripherally-derived macrophages does not affect tau pathology in young or old hTau mice. Glia. 2020 07; 68(7):1466-1478. Zhu K, Pieber M, Han J, Blomgren K, Zhang XM, Harris RA, Lund H. PMID: 32039516.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    14. miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation. Signal Transduct Target Ther. 2019; 4:27. Chen Y, Sun JX, Chen WK, Wu GC, Wang YQ, Zhu KY, Wang J. PMID: 31637007; PMCID: PMC6799846.
      View in: PubMed   Mentions: 30     Fields:    
    15. Repurposing of omeprazole for oligodendrocyte differentiation and remyelination. Brain Res. 2019 05 01; 1710:33-42. Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J. PMID: 30590025.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    16. Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders. Glia. 2019 02; 67(2):217-231. Han J, Zhu K, Zhang XM, Harris RA. PMID: 30378163; PMCID: PMC6635749.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    17. Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling. Nat Immunol. 2018 05; 19(5):1-7. Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. PMID: 29662171; PMCID: PMC7309278.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    18. Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance. Front Neurosci. 2016; 10:613. Zhu K, Sun J, Kang Z, Zou Z, Wu G, Wang J. PMID: 28119561; PMCID: PMC5222794.
      View in: PubMed   Mentions: 16  
    Keying's Networks
    Concepts (103)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (1)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSF Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).

    We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use. This site is running Profiles RNS version UCSF-v3.1.0-6-g69de2244 on PROFILES-PWEB03.

    Copyright © The Regents of the University of California.