Laralynne Przybyla, PhD

Title(s)Associate Professor, Biochemistry and Biophysics
SchoolSchool of Medicine
Address499 Illinois, #355
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Functional genomics in stem cell models: considerations and applications. Front Cell Dev Biol. 2023; 11:1236553. Shevade K, Peddada S, Mader K, Przybyla L. PMID: 37554308; PMCID: PMC10404852.
      View in: PubMed   Mentions:
    2. A new era in functional genomics screens. Nat Rev Genet. 2022 02; 23(2):89-103. Przybyla L, Gilbert LA. PMID: 34545248.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    3. Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic. Cell. 2021 09 02; 184(18):4651-4668.e25. Logan T, Simon MJ, Rana A, Cherf GM, Srivastava A, Davis SS, Low RLY, Chiu CL, Fang M, Huang F, Bhalla A, Llapashtica C, Prorok R, Pizzo ME, Calvert MEK, Sun EW, Hsiao-Nakamoto J, Rajendra Y, Lexa KW, Srivastava DB, van Lengerich B, Wang J, Robles-Colmenares Y, Kim DJ, Duque J, Lenser M, Earr TK, Nguyen H, Chau R, Tsogtbaatar B, Ravi R, Skuja LL, Solanoy H, Rosen HJ, Boeve BF, Boxer AL, Heuer HW, Dennis MS, Kariolis MS, Monroe KM, Przybyla L, Sanchez PE, Meisner R, Diaz D, Henne KR, Watts RJ, Henry AG, Gunasekaran K, Astarita G, Suh JH, Lewcock JW, DeVos SL, Di Paolo G. PMID: 34450028; PMCID: PMC8489356.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    4. Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10. Sci Rep. 2021 06 18; 11(1):12900. Wang X, Negrou E, Maloney MT, Bondar VV, Andrews SV, Montalban M, Llapashtica C, Maciuca R, Nguyen H, Solanoy H, Arguello A, Przybyla L, Moerke NJ, Huntwork-Rodriguez S, Henry AG. PMID: 34145320; PMCID: PMC8213766.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    5. Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia. Nat Neurosci. 2020 08; 23(8):927-938. Andreone BJ, Przybyla L, Llapashtica C, Rana A, Davis SS, van Lengerich B, Lin K, Shi J, Mei Y, Astarita G, Di Paolo G, Sandmann T, Monroe KM, Lewcock JW. PMID: 32514138.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    6. TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge. Neuron. 2020 03 04; 105(5):837-854.e9. Nugent AA, Lin K, van Lengerich B, Lianoglou S, Przybyla L, Davis SS, Llapashtica C, Wang J, Kim DJ, Xia D, Lucas A, Baskaran S, Haddick PCG, Lenser M, Earr TK, Shi J, Dugas JC, Andreone BJ, Logan T, Solanoy HO, Chen H, Srivastava A, Poda SB, Sanchez PE, Watts RJ, Sandmann T, Astarita G, Lewcock JW, Monroe KM, Di Paolo G. PMID: 31902528.
      View in: PubMed   Mentions: 193     Fields:    Translation:HumansAnimalsCells
    7. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol. 2018 10; 20(10):1203-1214. Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM. PMID: 30202050; PMCID: PMC6932748.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    8. Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discov. 2017 11; 7(11):1224-1237. Northey JJ, Przybyla L, Weaver VM. PMID: 29038232; PMCID: PMC5679454.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    9. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017 Jun 01; 28(11):1467-1488. Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, Ye X, Davidson MW, Lammerding J, Odde DJ, Dunn AR, Weaver VM. PMID: 28381423; PMCID: PMC5449147.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    10. Tissue mechanics regulate brain development, homeostasis and disease. J Cell Sci. 2017 01 01; 130(1):71-82. Barnes JM, Przybyla L, Weaver VM. PMID: 28043968; PMCID: PMC5394781.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    11. Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. Cell Stem Cell. 2016 10 06; 19(4):462-475. Przybyla L, Lakins JN, Weaver VM. PMID: 27452175; PMCID: PMC5336327.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    12. Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. Annu Rev Cell Dev Biol. 2016 10 06; 32:527-554. Przybyla L, Muncie JM, Weaver VM. PMID: 27298087.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    13. Monitoring developmental force distributions in reconstituted embryonic epithelia. Methods. 2016 Feb 01; 94:101-13. Przybyla L, Lakins JN, Sunyer R, Trepat X, Weaver VM. PMID: 26342256; PMCID: PMC4761493.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    14. Matrix remodeling maintains embryonic stem cell self-renewal by activating Stat3. Stem Cells. 2013 Jun; 31(6):1097-106. Przybyla LM, Theunissen TW, Jaenisch R, Voldman J. PMID: 23404867; PMCID: PMC3664106.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    15. Probing embryonic stem cell autocrine and paracrine signaling using microfluidics. Annu Rev Anal Chem (Palo Alto Calif). 2012; 5:293-315. Przybyla L, Voldman J. PMID: 22524217; PMCID: PMC4030416.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    16. Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):835-40. Przybyla LM, Voldman J. PMID: 22215601; PMCID: PMC3271888.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    17. Interactions of the cytoplasmic domain of Sindbis virus E2 with nucleocapsid cores promote alphavirus budding. J Virol. 2012 Mar; 86(5):2585-99. Jose J, Przybyla L, Edwards TJ, Perera R, Burgner JW, Kuhn RJ. PMID: 22190727; PMCID: PMC3302261.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    18. An engineered DNA-binding protein self-assembles metallic nanostructures. Chembiochem. 2010 Oct 18; 11(15):2108-12. Hall Sedlak R, Hnilova M, Gachelet E, Przybyla L, Dranow D, Gonen T, Sarikaya M, Tamerler C, Traxler B. PMID: 20827792.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    19. Conformational switching by the scaffolding protein D directs the assembly of bacteriophage phiX174. Mol Cell. 2004 Sep 24; 15(6):991-7. Morais MC, Fisher M, Kanamaru S, Przybyla L, Burgner J, Fane BA, Rossmann MG. PMID: 15383287.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    20. [Serum levels of salicylic acid in patients with psoriasis treated with 10% salicylic acid ointment]. Przegl Dermatol. 1990 Jan-Feb; 77(1):20-4. Zgrzyblowski A, Paradecki W, Przybyla L. PMID: 2200078.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
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