Laura Sanman, PhD

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentPharmaceutical Chemistry
Address1700 4th St
San Francisco CA 94158
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    1. Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA. TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development. Cell Rep. 2018 Mar 13; 22(11):2964-2977. PMID: 29539424.
      View in: PubMed
    2. Thorne CA, Chen IW, Sanman L, Cobb MH, Wu LF, Altschuler SJ. Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization. Dev Cell. 2018 Mar 12; 44(5):624-633.e4. PMID: 29503158.
      View in: PubMed
    3. Aillaud C, Bosc C, Peris L, Bosson A, Heemeryck P, Van Dijk J, Le Friec J, Boulan B, Vossier F, Sanman L, Syed S, Amara N, Couté Y, Lafanechère L, Denarier E, Delphin C, Pelletier L, Humbert S, Bogyo M, Andrieux A, Rogowski K, Moutin MJ. Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science. 2017 12 15; 358(6369):1448-1453. PMID: 29146868.
      View in: PubMed
    4. Sanman L, van der Linden WA, Verdoes M, Bogyo M. Bifunctional Probes of Cathepsin Protease Activity and pH Reveal Alterations in Endolysosomal pH during Bacterial Infection. Cell Chem Biol. 2016 Jul 21; 23(7):793-804. PMID: 27427229.
      View in: PubMed
    5. Sanman L, Qian Y, Eisele NA, Ng TM, van der Linden WA, Monack DM, Weerapana E, Bogyo M. Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. Elife. 2016 Mar 24; 5:e13663. PMID: 27011353; PMCID: PMC4846378.
    6. Withana NP, Ma X, McGuire HM, Verdoes M, van der Linden WA, Ofori LO, Zhang R, Li H, Sanman L, Wei K, Yao S, Wu P, Li F, Huang H, Xu Z, Wolters PJ, Rosen GD, Collard HR, Zhu Z, Cheng Z, Bogyo M. Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes. Sci Rep. 2016 Jan 22; 6:19755. PMID: 26797565; PMCID: PMC4726431.
    7. Hachmann J, Edgington-Mitchell LE, Poreba M, Sanman L, Drag M, Bogyo M, Salvesen GS. Probes to monitor activity of the paracaspase MALT1. Chem Biol. 2015 Jan 22; 22(1):139-47. PMID: 25556944; PMCID: PMC4304901.
    8. Godinat A, Budin G, Morales AR, Park HM, Sanman L, Bogyo M, Yu A, Stahl A, Dubikovskaya EA. A biocompatible "split luciferin" reaction and its application for non-invasive bioluminescent imaging of protease activity in living animals. Curr Protoc Chem Biol. 2014 Sep 09; 6(3):169-89. PMID: 25205565; PMCID: PMC4219325.
    9. Sanman L, Bogyo M. Activity-based profiling of proteases. Annu Rev Biochem. 2014; 83:249-73. PMID: 24905783.
      View in: PubMed
    10. Verdoes M, Oresic Bender K, Segal E, van der Linden WA, Syed S, Withana NP, Sanman L, Bogyo M. Improved quenched fluorescent probe for imaging of cysteine cathepsin activity. J Am Chem Soc. 2013 Oct 02; 135(39):14726-30. PMID: 23971698; PMCID: PMC3826460.
    11. Godinat A, Park HM, Miller SC, Cheng K, Hanahan D, Sanman L, Bogyo M, Yu A, Nikitin GF, Stahl A, Dubikovskaya EA. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. ACS Chem Biol. 2013 May 17; 8(5):987-99. PMID: 23463944; PMCID: PMC3836283.
    12. Sherrer SM, Sanman L, Xia CX, Bolin ER, Malik CK, Efthimiopoulos G, Basu AK, Suo Z. Kinetic analysis of the bypass of a bulky DNA lesion catalyzed by human Y-family DNA polymerases. Chem Res Toxicol. 2012 Mar 19; 25(3):730-40. PMID: 22324639; PMCID: PMC3307895.
    13. Brown JA, Pack LR, Sanman L, Suo Z. Efficiency and fidelity of human DNA polymerases ? and ß during gap-filling DNA synthesis. DNA Repair (Amst). 2011 Jan 02; 10(1):24-33. PMID: 20961817; PMCID: PMC3065367.
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