Lawrence Shiow • UCSF Profiles

Lawrence Shiow, MD, PhD

Title(s)	Assistant Professor, Pediatrics
School	School of Medicine
Address	Location Required, #001 Varies CA 00000
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Biography

Education and Training

University of California, San Francisco	Fellowship		Neonatology
University of California, San Francisco	Residency	2012	Pediatrics
University of California, San Francisco	M.D.	2010	School of Medicine
University of California, San Francisco	Ph.D.	2008	Biomedical Sciences (Immunology)

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Prenatal delivery of a therapeutic antisense oligonucleotide achieves broad biodistribution in the brain and ameliorates Angelman syndrome phenotype in mice. Mol Ther. 2024 Apr 03; 32(4):935-951. Clarke MT, Remesal L, Lentz L, Tan DJ, Young D, Thapa S, Namuduri SR, Borges B, Kirn G, Valencia J, Lopez ME, Lui JH, Shiow LR, Dindot S, Villeda S, Sanders SJ, MacKenzie TC. PMID: 38327047.

View in: PubMed Mentions: Fields:
Mol Molecular Biology The Therapeutics
Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis. Sci Immunol. 2020 11 20; 5(53). Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. PMID: 33219152; PMCID: PMC8043673.

View in: PubMed Mentions: 78 Fields:
All Allergy and Immunology
Translation:Humans Cells
Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature. 2019 09; 573(7772):75-82. Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH. PMID: 31316211; PMCID: PMC6731122.

View in: PubMed Mentions: 214 Fields:
Sci Science
Translation:Humans Animals Cells
Single-Cell Genomics Reveals Spatial and Stage-Associated Diversity in Multiple Sclerosis (P2.2-070). Neurology. 2019 Apr 9; 92(15_supplement). Schirmer SL, Velmeshev VD, Jung JD, Vistnes VS, Holmqvist HS, Tung TB, Goyal GN, Bhaduri BA, Mayer MS, Haeussler HM, Schafer SD, Reynolds RR, Shiow SL, Kriegstein KA, Rowitch RD. .

View in: Publisher Site Mentions:
Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity. Elife. 2018 09 11; 7. Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH. PMID: 30204081; PMCID: PMC6167053.

View in: PubMed Mentions: 40 Fields:
Bio Biology
Translation:Humans Animals Cells
Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury. Glia. 2017 12; 65(12):2024-2037. Shiow LR, Favrais G, Schirmer L, Schang AL, Cipriani S, Andres C, Wright JN, Nobuta H, Fleiss B, Gressens P, Rowitch DH. PMID: 28856805; PMCID: PMC5753598.

View in: PubMed Mentions: 48 Fields:
Neu Neurology
Translation:Humans Animals Cells
InlP, a New Virulence Factor with Strong Placental Tropism. Infect Immun. 2016 Dec; 84(12):3584-3596. Faralla C, Rizzuto GA, Lowe DE, Kim B, Cooke C, Shiow LR, Bakardjiev AI. PMID: 27736782; PMCID: PMC5116735.

View in: PubMed Mentions: 26 Fields:
All Allergy and Immunology Com Communicable Diseases
Translation:Animals Cells
Inhibiting the Prostaglandin Pathway for Neonatal Neuroprotection. Pediatrics. 2016 Feb 1; 137(Supplement 3):503a-503a. Shiow SL, Fleiss FB, Nobuta NH, Gressens GP, Rowitch RD. .

View in: Publisher Site Mentions:
Erratum: Corrigendum: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nature Neuroscience. 2014 Dec 1; 17(12):1841-1841. Fancy FS, Harrington HE, Baranzini BS, Silbereis SJ, Shiow SL, Yuen YT, Huang HE, Lomvardas LS, Rowitch RD. .

View in: Publisher Site Mentions:
Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nat Neurosci. 2014 Apr; 17(4):506-12. Fancy SP, Harrington EP, Baranzini SE, Silbereis JC, Shiow LR, Yuen TJ, Huang EJ, Lomvardas S, Rowitch DH. PMID: 24609463; PMCID: PMC3975168.

View in: PubMed Mentions: 67 Fields:
Neu Neurology
Translation:Humans Animals Cells
Severe Combined Immunodeficiency Due to Absent Coronin-1A. Primary Immunodeficiency Diseases. 2013 Nov 1; 294-296. Shiow SL, Paris PK, Puck PJ. .

View in: Publisher Site Mentions:
CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4. J Biol Chem. 2010 Jul 16; 285(29):22328-37. Bankovich AJ, Shiow LR, Cyster JG. PMID: 20463015; PMCID: PMC2903414.

View in: PubMed Mentions: 169 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion. Clin Immunol. 2009 Apr; 131(1):24-30. Shiow LR, Paris K, Akana MC, Cyster JG, Sorensen RU, Puck JM. PMID: 19097825; PMCID: PMC2692687.

View in: PubMed Mentions: 65 Fields:
All Allergy and Immunology
Translation:Humans Cells
The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency. Nat Immunol. 2008 Nov; 9(11):1307-15. Shiow LR, Roadcap DW, Paris K, Watson SR, Grigorova IL, Lebet T, An J, Xu Y, Jenne CN, Föger N, Sorensen RU, Goodnow CC, Bear JE, Puck JM, Cyster JG. PMID: 18836449; PMCID: PMC2672406.

View in: PubMed Mentions: 104 Fields:
All Allergy and Immunology
Translation:Humans Animals Cells
CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature. 2006 Mar 23; 440(7083):540-4. Shiow LR, Rosen DB, Brdicková N, Xu Y, An J, Lanier LL, Cyster JG, Matloubian M. PMID: 16525420.

View in: PubMed Mentions: 621 Fields:
Sci Science
Translation:Humans Animals Cells
High-performance multiplex SNP analysis of three hemochromatosis-related mutations with capillary array electrophoresis microplates. Genome Res. 2001 Mar; 11(3):413-21. Medintz I, Wong WW, Berti L, Shiow L, Tom J, Scherer J, Sensabaugh G, Mathies RA. PMID: 11230165; PMCID: PMC311034.

View in: PubMed Mentions: 6 Fields:
Gen Genetics
Translation:Humans