Leslie Floren, PharmD, PhD, MA

Title(s)Professor, Clinical Pharmacy
SchoolSchool of Pharmacy
Address513 Parnassus Ave, MSB, #947
San Francisco CA 94117
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco, CAPost-Doc Fellow/Scholar1997 School of Pharmacy
    University of California, San Francisco, CA Residency School of Pharmacy
    University of California, San Francisco, CAPharm.D.1994 School of Pharmacy
    University of California, Berkeley, CAMA12/2013Health Professions Education
    University of California, San Francisco, CA11/2020Diversity, Equity, and Inclusion Champion Training
    Collapse Awards and Honors
    2012UCSF Teaching Scholars Program
    2010Long Award for Excellence in Teaching
    2005  - 2012UCSF School of Pharmacy Dean’s Recognition for Excellence in Teaching
    1995  - 1997Postdoctoral Research Fellowship, Department of Biopharmaceutical Sciences, UCSF

    Collapse Overview 
    Collapse Overview
    Leslie Carstensen Floren, PharmD, DABCP is an Associate Adjunct Professor of Bioengineering and Therapeutic Sciences (BTS) in the School of Pharmacy at UCSF, the Academic Coordinator and Director of Professional and Postdoctoral Educational Affairs in BTS as well as the co-Director of the NIH-funded, UCSF Clinical Pharmacology Fellowship Training Program. Her teaching responsibilities for the past several years have included, primarily, teaching pharmacokinetics/pharmacodynamics, clinical pharmacology and principles of drug development and regulatory sciences to a wide variety of students, including professional students in the PharmD program, Clinical Pharmacology Fellows, junior faculty members, and working professionals from industrial backgrounds. Teaching is one of her greatest pleasures and she has been honored to receive the School of Pharmacy Dean’s Recognition for Excellence in Teaching every year since 2005 and, in 2010, she received the highest honor in the School of Pharmacy for teaching, the Long Award for Excellence in Teaching. Dr. Floren has a keen interest in curriculum development, teaching methodology and assessment, educational technology and online education and will begin training in the School of Medicine 2012-2013 Teaching Scholars Program in order to develop innovative curricula, to implement novel teaching methods and to use technology in order to “bring to life” the principles of Pharmacokinetics, Pharmacodynamics and Clinical Pharmacology for a wide variety of students within and across disciplines and, ultimately, to have a positive impact on patient health. She also plans to conduct scholarly research that will demonstrate the utility of practice-based teaching methods in order to advance interdisciplinary pharmaceutical sciences education within UCSF, our local community and across the country.

    Collapse Research 
    Collapse Research Activities and Funding
    General Clinical Research Center
    NIH M01RR000079Dec 1, 1974 - Mar 31, 2009
    Role: Co-Investigator

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    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Medical Residents' Informal Learning from Pharmacists in the Clinical Workplace. Med Sci Educ. 2023 May 06; 1-10. Floren LC, Pittenger AL, Wilting I, Irby DM, Cate OT. PMID: 37360063; PMCID: PMC10163287.
      View in: PubMed   Mentions:
    2. Fostering Interprofessional Geriatric Patient Care Skills for Health Professions Students Through a Nursing Facility-Based Immersion Rotation. MedEdPORTAL. 2020 12 24; 16:11059. Byerly LK, Floren LC, Yukawa M. PMID: 33409357; PMCID: PMC7780744.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Development of an interprofessional rotation for pharmacy and medical students to perform telehealth outreach to vulnerable patients in the COVID-19 pandemic. J Interprof Care. 2020 Sep-Oct; 34(5):694-697. Bautista CA, Huang I, Stebbins M, Floren LC, Wamsley M, Youmans SL, Hsia SL. PMID: 32917114.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    4. An interaction analysis model to study knowledge construction in interprofessional education: proof of concept. J Interprof Care. 2021 Sep-Oct; 35(5):736-743. Floren LC, Ten Cate O, Irby DM, O'Brien BC. PMID: 32811214.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Getting outside the box: exploring role fluidity in interprofessional student groups through the lens of activity theory. Adv Health Sci Educ Theory Pract. 2021 03; 26(1):253-275. Byerly LK, Floren LC, Yukawa M, O'Brien BC. PMID: 32705403.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. A Mobile Learning Module to Support Interprofessional Knowledge Construction in the Health Professions. Am J Pharm Educ. 2020 02; 84(2):847519. Floren LC, Mandal J, Dall'Era M, Shin J, Irby DM, Cate OT, O'Brien BC. PMID: 32226076; PMCID: PMC7092784.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Clinical Pharmacology Education - The Decade Ahead. Clin Pharmacol Ther. 2020 01; 107(1):37-39. Brouwer KLR, Schmidt S, Floren LC, Johnson JA. PMID: 31709518; PMCID: PMC6937203.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. A review of interprofessional training wards: Enhancing student learning and patient outcomes. Med Teach. 2019 05; 41(5):547-554. Oosterom N, Floren LC, Ten Cate O, Westerveld HE. PMID: 30394168.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    9. Are We on the Same Page? Shared Mental Models to Support Clinical Teamwork Among Health Professions Learners: A Scoping Review. Acad Med. 2018 03; 93(3):498-509. Floren LC, Donesky D, Whitaker E, Irby DM, Ten Cate O, O'Brien BC. PMID: 29028635.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    10. Changes in clearance, volume and bioavailability of immunosuppressants when given with HAART in HIV-1 infected liver and kidney transplant recipients. Biopharm Drug Dispos. 2013 Nov; 34(8):442-51. Frassetto L, Floren L, Barin B, Browne M, Wolfe A, Roland M, Stock P, Carlson L, Christians U, Benet L. PMID: 24030928; PMCID: PMC4018225.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    11. Cancer Chemother Pharmacol. Pharmacokinetic/pharmacodynamic analysis of adjuvant pegylated interferon alpha-2b in patients with resected high-risk melanoma. 2011; (67):657-66. Daud AI, Xu C, Hwu WJ, Urbas P, Andrews S, Papadopoulos NE, Floren LC, Yver A, Deconti RC, Sondak VK.
    12. Br J Cancer. Phase II trial of sagopilone, a novel epothilone analog in metastatic melanoma. 2010; (10):1548-53. DeConti RC, Algazi AP, Andrews S, Urbas P, Born O, Stoeckigt D, Floren L, Hwang J, Weber J, Sondak VK, Daud AI.
    13. Drug Metab Dispos. An Inhibitory Metabolite Leads to Dose- and Time-Dependent Pharmacokinetics of (R)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in Human Subjects After Multiple Dosing. 2009; (37):502-13. GR Tonn, SG Wong, SC Wong, MG Johnson, J Ma, R Cho, LC Floren, K Kersey, K Berry, AP Marcus, X Wang, B Van Lengerich, JC Medina, PG Pearson, and BK Wong.
    14. Safety and pharmacokinetics (PK) of T138067 (T67) administered as a weekly 3-hour infusion in subjects with hepatocellular carcinoma (HCC) in a phase 1 study. Journal of Clinical Oncology. 2004 Jul 15; 22(14_suppl):4087-4087. Venook VA, Rowinsky RE, Donehower DR, Leung LT, Floren FL, Levy LM. .
      View in: Publisher Site   Mentions:
    15. Safety and pharmacokinetics (PK) of T138067 (T67) administered as a weekly 3-hour infusion in subjects with hepatocellular carcinoma (HCC) in a phase 1 study. Journal of Clinical Oncology. 2004 Jul 15; 22(14_suppl):4087-4087. Venook VA, Rowinsky RE, Donehower DR, Leung LT, Floren FL, Levy LM. .
      View in: Publisher Site   Mentions:
    16. Drug Metab Pharmacokinet. Pharmacokinetic Interactions between Cyclosporine and Protease Inhibitors in HIV+ Subjects. 2003; (18):114-20. LA Frassetto, Thai T, Aggarwal A, Bucher P, Jacobsen W, U Christians, LZ Benet, LC Floren. .
    17. Pediatrics. Nelfinavir pharmacokinetics in stable HIV-positive children: AIDS Clinical Trials Group Protocol 377. 2003; 3(112):e220-27. LC Floren, A Wiznia , SA Hayashi, A Jaywardene, K Stanley, G Johnson, S Nachman, P Krosstad, F Aweeka.
    18. Clin Pharmacol Ther. The pharmacokinetics and metabolic disposition of tacrolimus: a comparison across ethnic groups. 2001; (69):24-31. L Mancinelli, L Frassetto, LC Floren, D Dressler, S Carrier, I Bekersky, LZ Benet, U Christians.
    19. Sirolimus oral bioavailability increases ten-fold with concomitant ketoconazole. Clinical Pharmacology & Therapeutics. 1999 Feb 1; 65(2):159-159. Floren FL, Christians CU, Zimmerman ZJ, Neefe NL, Schorer SR, Rushworth RD, Harper HD, Renz RJ, Benet BL. .
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    20. Pharmacol Ther. Metabolism and drug interactions of the 3-hydroxy-3methylglutaryl Coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?. 1998; (80):1-34. U Christians, W Jacobsen and LC Floren. .
    21. Ann Onc. Tamoxifen in liver disease: potential exacerbation of hepatic function. 1998; (9):1123-26. LC Floren, MF Hebert, AP Venook, VC Jordan, A Cisneros, and KA Somberg.
    22. CJHP. Pharmacogenetics: The clinical significance of cytochrome P450 polymorphisms. 1998; (10):11-4. C Cheng and LC Floren. .
    23. Clin Pharmacol Ther. Tacrolimus oral bioavailability doubles with co-administration of ketoconazole. 1997; (62):41-9. LC Floren, I Bekersky, LZ Benet, QA Mekki, DE Dressler, JW Lee, JP Roberts, and MF Hebert.
    24. Transplantationsmedizen. The clinical pharmacokinetics of macrolide immunosuppressants and its impact on the clinical management of organ transplantation. 1997; (9):S2-S6. U Christians, LC Floren, G Kirchner, and K-F Sewing.
    25. Foscarnet Pharmacokinetics (PK) During Continuous Ambulatory Peritoneal Dialysis (CAPD). Clinical Pharmacology & Therapeutics. 1996 Feb 1; 59(2):142-142. Floren FL, Gambertoglio GJ, Martin-Munley MS, Aweeka AF. .
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