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Li Zhang, PhD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address550 16th. Street
San Francisco CA 94158
Phone415-476-5339
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    Collapse Biography 
    Collapse Education and Training
    University of FloridaPh.D.2006Department of Statistics
    NCI/NIHPredoctoral Fellow2005Division of Cancer Epidemiology and Genetics
    University of FloridaM.S.2003Department of Statistics
    Southeast University, ChinaB.S.1999Civil Engineering
    Collapse Awards and Honors
    UCSF CTSI2017  - 2018Consultation Services Training Grant
    Prostate Cancer Foundation2017  - 2020The Movember Foundation-Challenge Award
    UCSF Helen Diller Family Comprehensive Cancer Center2016  - 2017UCSF Global Oncology Pilot Project Award
    NCI and UCSF Helen Diller Family Comprehensive Cancer Center2016  - 2017UCSF Research Allocation Program Award
    Prostate Cancer Foundation2014  - 2017The Safeway Foundation-PCF Challenge Award – The NEXT Project: Network Enriched Crossover Trial
    Cleveland Clinic2012  - 2012Innovator Award - Genomic Biomarkers of Lung Cancer Risk
    University of Florida2005  - 2006Keene Dissertation Fellowship Award

    Collapse Overview 

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Friedlander TW, Graff JN, Zejnullahu K, Anantharaman A, Zhang L, Paz R, Premasekharan G, Russell C, Huang Y, Kim W, Aggarwal RR, Lin AM, Fong L, Alumkal JJ, Beer TM, Sharifi N, Alyamani M, Dittamore R, Small EJ, Paris PL, Ryan CJ. High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer. Clin Genitourin Cancer. 2017 Dec; 15(6):733-741.e1. PMID: 28655452.
      View in: PubMed
    2. Peng Y, Li Y, Jian M, Liu X, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW, Chan MT, Han R. Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial. Int J Stroke. 2017 Dec; 12(9):991-997. PMID: 28436307.
      View in: PubMed
    3. Zhang L, Cham J, Paciorek A, Trager J, Sheikh N, Fong L. 3D: diversity, dynamics, differential testing - a proposed pipeline for analysis of next-generation sequencing T cell repertoire data. BMC Bioinformatics. 2017 Feb 27; 18(1):129. PMID: 28241742.
      View in: PubMed
    4. Aggarwal R, Bryce A, Ryan CJ, Harzstark A, Derleth C, Kim W, Friedlander T, Lin AM, Rodvelt-Bagchi T, Dhawan M, Zhang L, Lee M, Siebeneck E, Hough J, Small EJ. A multicenter phase I study of cabazitaxel, mitoxantrone, and prednisone for chemotherapy-naïve patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium study. Urol Oncol. 2017 Apr; 35(4):149.e7-149.e13. PMID: 28161323.
      View in: PubMed
    5. Oh DY, Cham J, Zhang L, Fong G, Kwek SS, Klinger M, Faham M, Fong L. Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire. Cancer Res. 2017 03 15; 77(6):1322-1330. PMID: 28031229.
      View in: PubMed
    6. Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L. Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer. Cancer Immunol Res. 2016 11; 4(11):948-958. PMID: 27688020.
      View in: PubMed
    7. Sheikh N, Cham J, Zhang L, DeVries T, Letarte S, Pufnock J, Hamm D, Trager J, Fong L. Clonotypic Diversification of Intratumoral T Cells Following Sipuleucel-T Treatment in Prostate Cancer Subjects. Cancer Res. 2016 07 01; 76(13):3711-8. PMID: 27216195.
      View in: PubMed
    8. Kwek SS, Kahn J, Greaney SK, Lewis J, Cha E, Zhang L, Weber RW, Leonard L, Markovic SN, Fong L, Spitler LE. GM-CSF and ipilimumab therapy in metastatic melanoma: Clinical outcomes and immunologic responses. Oncoimmunology. 2016 Apr; 5(4):e1101204. PMID: 27141383.
      View in: PubMed
    9. Kwek SS, Lewis J, Zhang L, Weinberg V, Greaney SK, Harzstark AL, Lin AM, Ryan CJ, Small EJ, Fong L. Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab. Cancer Immunol Res. 2015 Sep; 3(9):1008-16. PMID: 25968455; PMCID: PMC4561203.
      View in: PubMed, PubMed Central
    10. Hajj-Ali RA, Major J, Langford C, Hoffman GS, Clark T, Zhang L, Sun Z, Silverstein RL. The interface of inflammation and subclinical atherosclerosis in granulomatosis with polyangiitis (Wegener's): a preliminary study. Transl Res. 2015 Oct; 166(4):366-74. PMID: 26024800; PMCID: PMC4862201 [Available on 10/01/16].
      View in: PubMed, PubMed Central
    11. Seymour ZA, Chang AJ, Zhang L, Kirby N, Descovich M, Roach M, Hsu IC, Gottschalk AR. Dose-volume analysis and the temporal nature of toxicity with stereotactic body radiation therapy for prostate cancer. Pract Radiat Oncol. 2015 Sep-Oct; 5(5):e465-72. PMID: 25795252.
      View in: PubMed
    12. Cheng ML, Zhang L, Borok M, Chokunonga E, Dzamamala C, Korir A, Wabinga HR, Hiatt RA, Parkin DM, Van Loon K. The incidence of oesophageal cancer in Eastern Africa: identification of a new geographic hot spot? Cancer Epidemiol. 2015 Apr; 39(2):143-9. PMID: 25662402; PMCID: PMC4470609.
      View in: PubMed, PubMed Central
    13. V. Visconte, A. Tabarroki, L. Zhang, A.T. Gerds, H.J. Rogers, Y. Han, J. Barnard, V. Shivarov, J. Carew, R.V. Tiu .Somatic wiskott-aldrich syndrome protein family member 3 (WASF3) mutations in myelodysplastic syndromes and related myeloid malignancies. Leukemia Research. 2015; 39:S85-S86.
    14. Visconte V, Tabarroki A, Zhang L, Parker Y, Hasrouni E, Mahfouz R, Isono K, Koseki H, Sekeres MA, Saunthararajah Y, Barnard J, Lindner D, Rogers HJ, Tiu RV. Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts. J Hematol Oncol. 2014 Dec 07; 7:89. PMID: 25481243; PMCID: PMC4266210.
      View in: PubMed, PubMed Central
    15. Van Loon K, Zhang L, Keiser J, Carrasco C, Glass K, Ramirez MT, Bobiak S, Nakakura EK, Venook AP, Shah MH, Bergsland EK. Bone metastases and skeletal-related events from neuroendocrine tumors. Endocr Connect. 2015 Mar; 4(1):9-17. PMID: 25430999; PMCID: PMC4285767.
      View in: PubMed, PubMed Central
    16. Kim W, Zhang L, Wilton JH, Fetterly G, Mohler JL, Weinberg V, Morse A, Szmulewitz RZ, Friedlander TW, Fong L, Lin AM, Harzstark AL, Molina A, Small EJ, Ryan CJ. Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens. Clin Cancer Res. 2014 Dec 15; 20(24):6269-76. PMID: 25336698; PMCID: PMC4277885.
      View in: PubMed, PubMed Central
    17. Visconte V, Tabarroki A, Zhang L, Hasrouni E, Gerace C, Frum R, Ai J, Advani AS, Duong HK, Kalaycio M, Saunthararajah Y, Sekeres MA, His ED, Shetty S, Rogers HJ, Tiu RV. Clinicopathologic and molecular characterization of myeloid neoplasms harboring isochromosome 17(q10). Am J Hematol. 2014 Aug; 89(8):862. PMID: 24796269.
      View in: PubMed
    18. Timur AA, Murugesan G, Zhang L, Barnard J, Bhatt DL, Kottke-Marchant K. Multi-parameter assessment of platelet inhibition and its stability during aspirin and clopidogrel therapy. Thromb Res. 2014 Jul; 134(1):96-104. PMID: 24852729; PMCID: PMC4097303.
      View in: PubMed, PubMed Central
    19. Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O'Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, M Ridker P, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, März W, Murray SS, O'Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ. Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. Am J Hum Genet. 2014 Mar 06; 94(3):349-60. PMID: 24560520.
      View in: PubMed
    20. Manuel G. Afable II, Michael J. Clemente, Andres Jerez, Li Zhang, Holleh Husseinzadeh, Hanna Rajala, Satu Mustjoki, Hideki Makishima, Brittney E. Dienes, John Desamito, Alan Lichtin, Mikkael A. Sekeres, Brad Pohlman, Anjali Advani, Ramon V. Tiu, Jaroslaw P. Maciejewski.Large Granular Lymphocytic: Common Therapies and their Outcomes. Journal of Hematology and Transfusion. 2014; (2).
    21. Chaturvedi S, Carcioppolo D, Zhang L, McCrae KR. Management and outcomes for patients with TTP: analysis of 100 cases at a single institution. Am J Hematol. 2013 Jul; 88(7):560-5. PMID: 23605996.
      View in: PubMed
    22. Zhang L, Orloff MS, Reber S, Li S, Zhao Y, Eng C. cgaTOH: extended approach for identifying tracts of homozygosity. PLoS One. 2013; 8(3):e57772. PMID: 23469237; PMCID: PMC3585782.
      View in: PubMed, PubMed Central
    23. Orloff MS, Zhang L, Bebek G, Eng C. Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort. PLoS One. 2012; 7(2):e31975. PMID: 22384118; PMCID: PMC3288062.
      View in: PubMed, PubMed Central
    24. Zhang L, Liu R, Wang Z, Culver DA, Wu R. Modeling haplotype-haplotype interactions in case-control genetic association studies. Front Genet. 2012; 3:2. PMID: 22303409; PMCID: PMC3260479.
      View in: PubMed, PubMed Central
    25. Ghosh A, Murugesan G, Chen K, Zhang L, Wang Q, Febbraio M, Anselmo RM, Marchant K, Barnard J, Silverstein RL. Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms. Blood. 2011 Jun 09; 117(23):6355-66. PMID: 21478428; PMCID: PMC3122954.
      View in: PubMed, PubMed Central
    26. Zhang L, Mukherjee B, Hu B, Moreno V, Cooney KA. Semiparametric Bayesian modeling of random genetic effects in family-based association studies. Stat Med. 2009 Jan 15; 28(1):113-39. PMID: 18792083; PMCID: PMC2684653.
      View in: PubMed, PubMed Central
    27. Zhang L, Mukherjee B, Ghosh M, Gruber S, Moreno V. Accounting for error due to misclassification of exposures in case-control studies of gene-environment interaction. Stat Med. 2008 Jul 10; 27(15):2756-83. PMID: 17879261.
      View in: PubMed
    28. Bong-Rae Kim, Li Zhang, Arthur Berg, Jianqing Fan and Rongling Wu.A Computational Approach to the Functional Clustering of Periodic Gene Expression Profiles. Genetics. 2008; (180):1-14.
    29. Robert Dorazio, Bhramar Mukherjee, Li Zhang, Malay Ghosh, Howard L. Jelks, and Frank Jordan.Modeling Unobserved Sources of Heterogeneity in Animal Abundance using a Dirichlet Process Prior. Biometrics. 2008; 2(64):635-644.
    30. Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C. Breast-cancer stromal cells with TP53 mutations and nodal metastases. N Engl J Med. 2007 Dec 20; 357(25):2543-51. PMID: 18094375.
      View in: PubMed
    31. Weber F, Xu Y, Zhang L, Patocs A, Shen L, Platzer P, Eng C. Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma. JAMA. 2007 Jan 10; 297(2):187-95. PMID: 17213402.
      View in: PubMed
    32. Bhramar Mukherjee, Li Zhang, Malay Ghosh and Samiran Sinha.Semiparametric Bayesian Analysis of Case-Control Data under Conditional Gene-Environment Independence. Biometrics. 2007; (63):834-844.
    33. Li Zhang, Bhramar Mukherjee, Malay Ghosh and Rongling Wu. .A Bayesian Framework for Genetic Association in Case-Control Studies: Accounting for Unknown Population Substructure. Statistical Modeling. 2006; (6):352-372.
    34. Malay Ghosh, Li Zhang and Bhramar Mukherjee.Equivalence of Posteriors in the Bayesian Analysis of The Multinomial-Poisson Transformation. Metron - International Journal of Statistics. 2006; 1(LXIV):19-28.
    35. Zhang L, Yang MC, Wang X, Larkins BA, Gallo-Meagher M, Wu R. A model for estimating joint maternal-offspring effects on seed development in autogamous plants. Physiol Genomics. 2004 Nov 17; 19(3):262-9. PMID: 15548832.
      View in: PubMed
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