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SARS-CoV-2 infection studies in lung organoids identify TSPAN8 as novel mediator. bioRxiv. 2021 Jun 02.
Hysenaj L, Little S, Kulhanek K, Gbenedio OM, Rodriguez L, Shen A, Lone JC, Lupin-Jimenez LC, Bonser LR, Serwas NK, Bahl K, Mick E, Li JZ, Ding VW, Matsumoto S, Maishan M, Simoneau C, Fragiadakis G, Jablons DM, Langelier CR, Matthay M, Ott M, Krummel M, Combes AJ, Sil A, Erle DJ, Kratz JR, Roose JP. PMID: 34100012.
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Epithelial miR-141 regulates IL-13-induced airway mucus production. JCI Insight. 2021 03 08; 6(5).
Siddiqui S, Johansson K, Joo A, Bonser LR, Koh KD, Le Tonqueze O, Bolourchi S, Bautista RA, Zlock L, Roth TL, Marson A, Bhakta NR, Ansel KM, Finkbeiner WE, Erle DJ, Woodruff PG. PMID: 33682796.
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1 Fields:
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Flow-Cytometric Analysis and Purification of Airway Epithelial-Cell Subsets. Am J Respir Cell Mol Biol. 2021 03; 64(3):308-317.
Bonser LR, Koh KD, Johansson K, Choksi SP, Cheng D, Liu L, Sun DI, Zlock LT, Eckalbar WL, Finkbeiner WE, Erle DJ. PMID: 33196316.
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6 Fields:
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HumansCells
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The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epithelium. bioRxiv. 2021 Feb 25.
Bonser LR, Eckalbar WL, Rodriguez L, Shen J, Koh KD, Zlock LT, Christenson S, Woodruff PG, Finkbeiner WE, Erle DJ. PMID: 33655249.
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Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men. Cell Stem Cell. 2020 12 03; 27(6):876-889.e12.
Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, Ramirez JT, Asgharian H, Simoneau CR, Bonser LR, Koh KD, Garcia-Knight M, Tassetto M, Sunshine S, Farahvashi S, Kalantari A, Liu W, Andino R, Zhao H, Natarajan P, Erle DJ, Ott M, Goodarzi H, Fattahi F. PMID: 33232663.
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38 Fields:
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HumansAnimalsCells
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Whole-Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth. Am J Respir Crit Care Med. 2020 10 01; 202(7):962-972.
Lee EY, Mak ACY, Hu D, Sajuthi S, White MJ, Keys KL, Eckalbar W, Bonser L, Huntsman S, Urbanek C, Eng C, Jain D, Abecasis G, Kang HM, Germer S, Zody MC, Nickerson DA, Erle D, Ziv E, Rodriguez-Santana J, Seibold MA, Burchard EG. PMID: 32459537.
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1 Fields:
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HumansCells
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Efficient RNP-directed Human Gene Targeting Reveals SPDEF Is Required for IL-13-induced Mucostasis. Am J Respir Cell Mol Biol. 2020 03; 62(3):373-381.
Koh KD, Siddiqui S, Cheng D, Bonser LR, Sun DI, Zlock LT, Finkbeiner WE, Woodruff PG, Erle DJ. PMID: 31596609.
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11 Fields:
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HumansCells
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The airway epithelium in asthma. Adv Immunol. 2019; 142:1-34.
Bonser LR, Erle DJ. PMID: 31296301.
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6 Fields:
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HumansAnimalsCells
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Putting Mucins on the Map. Am J Respir Crit Care Med. 2019 Mar 15; 199(6):681-682.
Bonser LR, Erle DJ. PMID: 30376352.
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1 Fields:
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Humans
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An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup. J Clin Invest. 2019 01 02; 129(1):169-181.
Christenson SA, van den Berge M, Faiz A, Inkamp K, Bhakta N, Bonser LR, Zlock LT, Barjaktarevic IZ, Barr RG, Bleecker ER, Boucher RC, Bowler RP, Comellas AP, Curtis JL, Han MK, Hansel NN, Hiemstra PS, Kaner RJ, Krishnanm JA, Martinez FJ, O'Neal WK, Paine R, Timens W, Wells JM, Spira A, Erle DJ, Woodruff PG. PMID: 30383540.
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23 Fields:
Translation:
Humans
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IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma. Am J Respir Crit Care Med. 2018 02 01; 197(3):313-324.
Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG. PMID: 29064281.
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29 Fields:
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HumansCells
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Airway Mucus and Asthma: The Role of MUC5AC and MUC5B. J Clin Med. 2017 Nov 29; 6(12).
Bonser LR, Erle DJ. PMID: 29186064.
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MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma. Chest. 2017 10; 152(4):771-779.
Welsh KG, Rousseau K, Fisher G, Bonser LR, Bradding P, Brightling CE, Thornton DJ, Gaillard EA. PMID: 28716644.
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22 Fields:
Translation:
Humans
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Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma. J Clin Invest. 2016 06 01; 126(6):2367-71.
Bonser LR, Zlock L, Finkbeiner W, Erle DJ. PMID: 27183390.
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49 Fields:
Translation:
Humans
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The Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):536-43.
Bonser LR, Schroeder BW, Ostrin LA, Baumlin N, Olson JL, Salathe M, Erle DJ. PMID: 25751668.
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10 Fields:
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HumansAnimalsCells
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Epithelial interleukin-25 is a key mediator in Th2-high, corticosteroid-responsive asthma. Am J Respir Crit Care Med. 2014 Sep 15; 190(6):639-48.
Cheng D, Xue Z, Yi L, Shi H, Zhang K, Huo X, Bonser LR, Zhao J, Xu Y, Erle DJ, Zhen G. PMID: 25133876.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells