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Manu Hegde, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Address513 Parnassus Avenue, MSB
San Francisco CA 94117
Phone415-353-2273
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California, Davis, CAM.D.2005School of Medicine
    University of California, Davis, CAPh.D.2006Neuroscience
    University of California, San Francisco, CA2009Neurology residency
    University of California, San Francisco, CA2011Epilepsy fellowship
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    Dr. Manu Hegde is a neurologist and epilepsy specialist who cares for adults who have seizures. He treats seizure disorders using the full spectrum of medications and is skilled at using cutting-edge imaging and neurophysiological tools that measure nervous system responses.

    Hegde is experienced at guiding patients who are interested in pursuing surgery for epilepsy, including looking at the option of implantable neurostimulation devices. Committed to helping patients improve their quality of life, he takes a holistic approach that aims to do more than just control seizures.

    Hegde's research focuses on finding epilepsy biomarkers, factors that might predict the effectiveness of treatment before patients actually have a seizure. He is a principal investigator for the Human Epilepsy Project, a large multicenter observational study of people with epilepsy. His other research interests include the links between epilepsy and autoimmune disease, improving mental health care for people with seizures and improving patient safety.

    Hegde earned his medical degree and a doctorate in neuroscience at the University of California, Davis. He completed a residency in neurology at UCSF, serving as a chief neurology resident for Moffitt Hospital in his final year. He then completed a fellowship in epilepsy and clinical neurophysiology at UCSF before joining the faculty. He is a fellow of the American Epilepsy Society and a member of the American Academy of Neurology.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. New Ethical and Clinical Challenges in "Closed-Loop" Neuromodulation. Neurology. 2021 Mar 16. Hegde M, Chiong W, Rao VR. PMID: 33727407.
      View in: PubMed   Mentions:    Fields:    
    2. Mesial temporal resection following long-term ambulatory intracranial EEG monitoring with a direct brain-responsive neurostimulation system. Epilepsia. 2020 03; 61(3):408-420. Hirsch LJ, Mirro EA, Salanova V, Witt TC, Drees CN, Brown MG, Lee RW, Sadler TL, Felton EA, Rutecki P, Shin HW, Hadar E, Hegde M, Rao VR, Mnatsakanyan L, Madhavan DS, Zakaria TJ, Liu AA, Heck CN, Greenwood JE, Bigelow JK, Nair DR, Alexopoulos AV, Mackow M, Edwards JC, Sotudeh N, Kuzniecky RI, Gwinn RP, Doherty MJ, Geller EB, Morrell MJ. PMID: 32072621.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Differential sensitivity of structural, diffusion, and resting-state functional MRI for detecting brain alterations and verbal memory impairment in temporal lobe epilepsy. Epilepsia. 2019 05; 60(5):935-947. Chang YA, Marshall A, Bahrami N, Mathur K, Javadi SS, Reyes A, Hegde M, Shih JJ, Paul BM, Hagler DJ, McDonald CR. PMID: 31020649.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Cognitive phenotypes in temporal lobe epilepsy are associated with distinct patterns of white matter network abnormalities. Neurology. 2019 04 23; 92(17):e1957-e1968. Reyes A, Kaestner E, Bahrami N, Balachandra A, Hegde M, Paul BM, Hermann B, McDonald CR. PMID: 30918094.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    5. Beyond depression: The impact of executive functioning on quality of life in patients with temporal lobe epilepsy. Epilepsy Res. 2019 01; 149:30-36. Ehrlich T, Reyes A, Paul BM, Uttarwar V, Hartman S, Mathur K, Chang YA, Hegde M, Shih JJ, McDonald CR. PMID: 30468945.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Staff Response Times in the Epilepsy Monitoring Unit: A Study of Diurnal/Nocturnal Variability. Neurodiagn J. 2017; 57(4):269-275. Witek N, Cornes S, Hegde M. PMID: 29236612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Cerebral metabolite changes prior to and after antiretroviral therapy in primary HIV infection. Neurology. 2014 Oct 28; 83(18):1592-600. Young AC, Yiannoutsos CT, Hegde M, Lee E, Peterson J, Walter R, Price RW, Meyerhoff DJ, Spudich S. PMID: 25261502.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    8. The search for circulating epilepsy biomarkers. Biomark Med. 2014; 8(3):413-27. Hegde M, Lowenstein DH. PMID: 24712433.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    9. Diagnostic yield of electroencephalography in the medical and surgical intensive care unit. Neurocrit Care. 2013 Dec; 19(3):336-41. Kamel H, Betjemann JP, Navi BB, Hegde M, Meisel K, Douglas VC, Josephson SA. PMID: 22820998.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    10. Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol. 2013 Sep 01; 70(9):1158-66. Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. PMID: 23835471.
      View in: PubMed   Mentions: 143     Fields:    Translation:Humans
    11. Seizure exacerbation in two patients with focal epilepsy following marijuana cessation. Epilepsy Behav. 2012 Dec; 25(4):563-6. Hegde M, Santos-Sanchez C, Hess CP, Kabir AA, Garcia PA. PMID: 23159379.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    12. Detection of atrial fibrillation after stroke and the risk of recurrent stroke. J Stroke Cerebrovasc Dis. 2012 Nov; 21(8):726-31. Kamel H, Johnson DR, Hegde M, Go AS, Sidney S, Sorel M, Hills NK, Johnston SC. PMID: 21546265.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Cost-effectiveness of outpatient cardiac monitoring to detect atrial fibrillation after ischemic stroke. Stroke. 2010 Jul; 41(7):1514-20. Kamel H, Hegde M, Johnson DR, Gage BF, Johnston SC. PMID: 20508188.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    14. Electroconvulsive therapy for refractory status epilepticus: a case series. Neurocrit Care. 2010 Apr; 12(2):204-10. Kamel H, Cornes SB, Hegde M, Hall SE, Josephson SA. PMID: 19809802.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
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