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Manu Hegde, MD, PhD

Title(s)Associate Professor, Neurology
SchoolSchool of Medicine
Phone415-353-2273
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of California DavisM.D.2005School of Medicine
    University of California, San FranciscoPh.D.1999 Graduate Division (Biomedical Sciences)
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 
    Collapse Overview
    Dr. Manu Hegde is an Assistant Professor in the Department of Neurology at UCSF. He is also a Staff Physician at the Epilepsy Center of Excellence at the San Francisco Veterans Affairs Medical Center (http://www.epilepsy.va.gov). He received a BA with honors in psychobiology from Claremont McKenna College, before earning a medical degree and a doctorate in neuroscience at the University of California, Davis. He then completed a medicine internship at Alameda County Medical Center in Oakland, followed by a neurology residency at UCSF, where he served as a chief neurology resident for Moffitt Hospital in his final year. He completed a fellowship in epilepsy and clinical neurophysiology at UCSF before joining the faculty.

    Dr. Hegde cares for adults with seizures, teaches trainees, and conducts research. His primary research interest is the discovery of epilepsy biomarkers, and he is a principal investigator for the Human Epilepsy Project (http://humanepilepsyproject.org), a large multicenter prospective study of people with focal epilepsy. His other interests include the utilization of novel techniques to improve seizure localization, developing an algorithm for epilepsy surgery candidacy, studying sudden unexpected death in epilepsy (SUDEP), and understanding links between epilepsy and autoimmune disease. He has published on a variety of topics, and has received research funding from NIH/NINDS, as well as nongovernmental organizations.

    Collapse Research 
    Collapse Research Activities and Funding
    Magnetoencephalographic detection of high-frequency activity in epilepsy patients
    NIH F32NS071738Aug 1, 2010 - Oct 31, 2012
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chang YA, Marshall A, Bahrami N, Mathur K, Javadi SS, Reyes A, Hegde M, Shih JJ, Paul BM, Hagler DJ, McDonald CR. Differential sensitivity of structural, diffusion, and resting-state functional MRI for detecting brain alterations and verbal memory impairment in temporal lobe epilepsy. Epilepsia. 2019 May; 60(5):935-947. PMID: 31020649.
      View in: PubMed
    2. Reyes A, Kaestner E, Bahrami N, Balachandra A, Hegde M, Paul BM, Hermann B, McDonald CR. Cognitive phenotypes in temporal lobe epilepsy are associated with distinct patterns of white matter network abnormalities. Neurology. 2019 Apr 23; 92(17):e1957-e1968. PMID: 30918094.
      View in: PubMed
    3. Ehrlich T, Reyes A, Paul BM, Uttarwar V, Hartman S, Mathur K, Chang YA, Hegde M, Shih JJ, McDonald CR. Beyond depression: The impact of executive functioning on quality of life in patients with temporal lobe epilepsy. Epilepsy Res. 2019 01; 149:30-36. PMID: 30468945.
      View in: PubMed
    4. Witek N, Cornes S, Hegde M. Staff Response Times in the Epilepsy Monitoring Unit: A Study of Diurnal/Nocturnal Variability. Neurodiagn J. 2017; 57(4):269-275. PMID: 29236612.
      View in: PubMed
    5. Young AC, Yiannoutsos CT, Hegde M, Lee E, Peterson J, Walter R, Price RW, Meyerhoff DJ, Spudich S. Cerebral metabolite changes prior to and after antiretroviral therapy in primary HIV infection. Neurology. 2014 Oct 28; 83(18):1592-600. PMID: 25261502.
      View in: PubMed
    6. Hegde M, Lowenstein DH. The search for circulating epilepsy biomarkers. Biomark Med. 2014; 8(3):413-27. PMID: 24712433.
      View in: PubMed
    7. Kamel H, Betjemann JP, Navi BB, Hegde M, Meisel K, Douglas VC, Josephson SA. Diagnostic yield of electroencephalography in the medical and surgical intensive care unit. Neurocrit Care. 2013 Dec; 19(3):336-41. PMID: 22820998.
      View in: PubMed
    8. Vossel KA, Beagle AJ, Rabinovici GD, Shu H, Lee SE, Naasan G, Hegde M, Cornes SB, Henry ML, Nelson AB, Seeley WW, Geschwind MD, Gorno-Tempini ML, Shih T, Kirsch HE, Garcia PA, Miller BL, Mucke L. Seizures and epileptiform activity in the early stages of Alzheimer disease. JAMA Neurol. 2013 Sep 01; 70(9):1158-66. PMID: 23835471; PMCID: PMC4013391.
      View in: PubMed, PubMed Central
    9. Hegde M, Santos-Sanchez C, Hess CP, Kabir AA, Garcia PA. Seizure exacerbation in two patients with focal epilepsy following marijuana cessation. Epilepsy Behav. 2012 Dec; 25(4):563-6. PMID: 23159379.
      View in: PubMed
    10. Kamel H, Johnson DR, Hegde M, Go AS, Sidney S, Sorel M, Hills NK, Johnston SC. Detection of atrial fibrillation after stroke and the risk of recurrent stroke. J Stroke Cerebrovasc Dis. 2012 Nov; 21(8):726-31. PMID: 21546265.
      View in: PubMed
    11. Kamel H, Hegde M, Johnson DR, Gage BF, Johnston SC. Cost-effectiveness of outpatient cardiac monitoring to detect atrial fibrillation after ischemic stroke. Stroke. 2010 Jul; 41(7):1514-20. PMID: 20508188.
      View in: PubMed
    12. Kamel H, Cornes SB, Hegde M, Hall SE, Josephson SA. Electroconvulsive therapy for refractory status epilepticus: a case series. Neurocrit Care. 2010 Apr; 12(2):204-10. PMID: 19809802.
      View in: PubMed
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