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Caspase-8 restricts antiviral CD8 T cell hyperaccumulation. Proc Natl Acad Sci U S A. 2019 07 23; 116(30):15170-15177.
Feng Y, Daley-Bauer LP, Roback L, Guo H, Koehler HS, Potempa M, Lanier LL, Mocarski ES. PMID: 31285326.
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4 Fields:
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AnimalsCells
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Caspase-8 restricts natural killer cell accumulation during MCMV Infection. Med Microbiol Immunol. 2019 Aug; 208(3-4):543-554.
Feng Y, Daley-Bauer LP, Roback L, Potempa M, Lanier LL, Mocarski ES. PMID: 31115653.
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AnimalsCells
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HIV-1 Protease Uses Bi-Specific S2/S2' Subsites to Optimize Cleavage of Two Classes of Target Sites. J Mol Biol. 2018 12 07; 430(24):5182-5195.
Potempa M, Lee SK, Kurt Yilmaz N, Nalivaika EA, Rogers A, Spielvogel E, Carter CW, Schiffer CA, Swanstrom R. PMID: 30414407.
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3 Fields:
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Using Primer-ID Deep Sequencing to Detect Recent Human Immunodeficiency Virus Type 1 Infection. J Infect Dis. 2018 10 20; 218(11):1777-1782.
Dennis AM, Zhou S, Sellers CJ, Learner E, Potempa M, Cohen MS, Miller WC, Eron JJ, Swanstrom R. PMID: 30010965.
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5 Fields:
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HumansCells
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A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nat Med. 2018 07; 24(7):1005-1014.
Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. PMID: 29942088.
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37 Fields:
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HumansAnimalsCells
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Cutting Edge: IL-2-Induced Expression of the Amino Acid Transporters SLC1A5 and CD98 Is a Prerequisite for NKG2D-Mediated Activation of Human NK Cells. J Immunol. 2017 09 15; 199(6):1967-1972.
Jensen H, Potempa M, Gotthardt D, Lanier LL. PMID: 28784848.
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13 Fields:
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HumansCells
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A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro. J Mol Biol. 2015 Jul 17; 427(14):2360-78.
Potempa M, Nalivaika E, Ragland D, Lee SK, Schiffer CA, Swanstrom R. PMID: 25986307.
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5 Fields:
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The triple threat of HIV-1 protease inhibitors. Curr Top Microbiol Immunol. 2015; 389:203-41.
Potempa M, Lee SK, Wolfenden R, Swanstrom R. PMID: 25778681.
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3 Fields:
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A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsid. Biochemistry. 2013 Jul 23; 52(29):4929-40.
Lee SK, Cheng N, Hull-Ryde E, Potempa M, Schiffer CA, Janzen W, Swanstrom R. PMID: 23763575.
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3 Fields:
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HumansCells
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Integrating the HIV-1 assembly/maturation pathway. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8327-8.
Potempa M, Swanstrom R. PMID: 23671082.
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The choreography of HIV-1 proteolytic processing and virion assembly. J Biol Chem. 2012 Nov 30; 287(49):40867-74.
Lee SK, Potempa M, Swanstrom R. PMID: 23043111.
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60 Fields:
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HumansCells
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Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease. J Biol Chem. 2012 Apr 13; 287(16):13279-90.
Lee SK, Potempa M, Kolli M, Özen A, Schiffer CA, Swanstrom R. PMID: 22334652.
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22 Fields:
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Cells