Marco Yannic Hein, PhD

TitlePostdoc Research Associate
InstitutionUniversity of California San Francisco
DepartmentHoward Hughes Medical Instit
Address1700 4th Street
San Francisco CA 94158
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein M, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15; 167(7):1867-1882.e21. PMID: 27984733.
      View in: PubMed
    2. Saha S, Weber CA, Nousch M, Adame-Arana O, Hoege C, Hein M, Osborne-Nishimura E, Mahamid J, Jahnel M, Jawerth L, Pozniakovski A, Eckmann CR, Jülicher F, Hyman AA. Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism. Cell. 2016 Sep 08; 166(6):1572-1584.e16. PMID: 27594427; PMCID: PMC5034880 [Available on 09/08/17].
    3. Ma-Lauer Y, Carbajo-Lozoya J, Hein M, Müller MA, Deng W, Lei J, Meyer B, Kusov Y, von Brunn B, Bairad DR, Hünten S, Drosten C, Hermeking H, Leonhardt H, Mann M, Hilgenfeld R, von Brunn A. p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):E5192-201. PMID: 27519799.
      View in: PubMed
    4. Tyanova S, Temu T, Sinitcyn P, Carlson A, Hein M, Geiger T, Mann M, Cox J. The Perseus computational platform for comprehensive analysis of (prote)omics data. Nat Methods. 2016 09; 13(9):731-40. PMID: 27348712.
      View in: PubMed
    5. Sarov M, Barz C, Jambor H, Hein M, Schmied C, Suchold D, Stender B, Janosch S, K J VV, Krishnan RT, Krishnamoorthy A, Ferreira IR, Ejsmont RK, Finkl K, Hasse S, Kämpfer P, Plewka N, Vinis E, Schloissnig S, Knust E, Hartenstein V, Mann M, Ramaswami M, VijayRaghavan K, Tomancak P, Schnorrer F. A genome-wide resource for the analysis of protein localisation in Drosophila. Elife. 2016 Feb 20; 5:e12068. PMID: 26896675; PMCID: PMC4805545.
    6. Hein M, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22; 163(3):712-23. PMID: 26496610.
      View in: PubMed
    7. Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein M, Mann A, Mann M, Habermann B, Pichlmair A. mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. Nat Commun. 2015 Sep 18; 6:8192. PMID: 26382858; PMCID: PMC4595607.
    8. Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein M, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S. A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation. Cell. 2015 Aug 27; 162(5):1066-77. PMID: 26317470.
      View in: PubMed
    9. Räschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein M, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M. DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links. Science. 2015 May 01; 348(6234):1253671. PMID: 25931565.
      View in: PubMed
    10. Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein M, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S, Schmidt-Supprian M. Continuous T cell receptor signals maintain a functional regulatory T cell pool. Immunity. 2014 Nov 20; 41(5):722-36. PMID: 25464853.
      View in: PubMed
    11. Keilhauer EC, Hein M, Mann M. Accurate protein complex retrieval by affinity enrichment mass spectrometry (AE-MS) rather than affinity purification mass spectrometry (AP-MS). Mol Cell Proteomics. 2015 Jan; 14(1):120-35. PMID: 25363814; PMCID: PMC4288248.
    12. Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein M, Wallis M, McGaughran J, Gecz J, Sluis Bv, Billadeau DD, Burstein E. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2015 Jan 01; 26(1):91-103. PMID: 25355947; PMCID: PMC4279232.
    13. Wisniewski JR, Hein M, Cox J, Mann M. A "proteomic ruler" for protein copy number and concentration estimation without spike-in standards. Mol Cell Proteomics. 2014 Dec; 13(12):3497-506. PMID: 25225357; PMCID: PMC4256500.
    14. Borner GH, Hein M, Hirst J, Edgar JR, Mann M, Robinson MS. Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein-protein interactions. Mol Biol Cell. 2014 Oct 15; 25(20):3178-94. PMID: 25165137.
      View in: PubMed
    15. Nández R, Balkin DM, Messa M, Liang L, Paradise S, Czapla H, Hein M, Duncan JS, Mann M, De Camilli P. A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells. Elife. 2014 Aug 08; 3:e02975. PMID: 25107275; PMCID: PMC4358339.
    16. Wueseke O, Bunkenborg J, Hein M, Zinke A, Viscardi V, Woodruff JB, Oegema K, Mann M, Andersen JS, Hyman AA. The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix. Mol Biol Cell. 2014 Oct 01; 25(19):2984-92. PMID: 25103243; PMCID: PMC4230587.
    17. Cox J, Hein M, Luber CA, Paron I, Nagaraj N, Mann M. Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ. Mol Cell Proteomics. 2014 Sep; 13(9):2513-26. PMID: 24942700; PMCID: PMC4159666.
    18. Zanivan S, Maione F, Hein M, Hernández-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M. SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers. Mol Cell Proteomics. 2013 Dec; 12(12):3599-611. PMID: 23979707; PMCID: PMC3861710.
    19. Hirst J, Borner GH, Edgar J, Hein M, Mann M, Buchholz F, Antrobus R, Robinson MS. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell. 2013 Aug; 24(16):2558-69. PMID: 23825025.
      View in: PubMed
    20. Vahl JC, Heger K, Knies N, Hein M, Boon L, Yagita H, Polic B, Schmidt-Supprian M. NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology. PLoS Biol. 2013; 11(6):e1001589. PMID: 23853545; PMCID: PMC3708704.
    21. Starokadomskyy P, Gluck N, Li H, Chen B, Wallis M, Maine GN, Mao X, Zaidi IW, Hein M, McDonald FJ, Lenzner S, Zecha A, Ropers HH, Kuss AW, McGaughran J, Gecz J, Burstein E. CCDC22 deficiency in humans blunts activation of proinflammatory NF-?B signaling. J Clin Invest. 2013 May; 123(5):2244-56. PMID: 23563313; PMCID: PMC3635737.
    22. Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein M, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility. Cell. 2013 Feb 14; 152(4):909-22. PMID: 23394947; PMCID: PMC3652613.
    23. Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein M, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS. Decoding human cytomegalovirus. Science. 2012 Nov 23; 338(6110):1088-93. PMID: 23180859; PMCID: PMC3817102.
    24. Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein M, Poser I, Mann M, Hyman AA, Weissman JS. Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. Cell. 2012 Jun 08; 149(6):1339-52. PMID: 22682253; PMCID: PMC3613983.