Margaret Lowe

Title(s)Associate Researcher, Dermatology
SchoolSchool of Medicine
Address2340 Sutter Street
San Francisco CA 94115
Phone415-502-3337
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Layilin Anchors Regulatory T Cells in Skin. J Immunol. 2021 10 01; 207(7):1763-1775. Mehta P, Gouirand V, Boda DP, Zhang J, Gearty SV, Zirak B, Lowe MM, Clancy S, Boothby I, Mahuron KM, Fries A, Krummel MF, Mankoo P, Chang HW, Liu J, Moreau JM, Scharschmidt TC, Daud A, Kim E, Neuhaus IM, Harris HW, Liao W, Rosenblum MD. PMID: 34470859.
      View in: PubMed   Mentions:    Fields:    
    2. Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation. Sci Immunol. 2021 Aug 27; 6(62). Moreau JM, Dhariwala MO, Gouirand V, Boda DP, Boothby IC, Lowe MM, Cohen JN, Macon CE, Leech JM, Kalekar LA, Scharschmidt TC, Rosenblum MD. PMID: 34452925.
      View in: PubMed   Mentions:    Fields:    
    3. B Home or You Are In Trouble: B Cell Integrin-Mediated Recruitment Attenuates Skin Inflammation. J Invest Dermatol. 2021 Aug; 141(8):1885-1887. Moreau JM, Lowe MM. PMID: 34303469.
      View in: PubMed   Mentions:    Fields:    
    4. Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment. J Exp Med. 2021 04 05; 218(4). Pauken KE, Shahid O, Lagattuta KA, Mahuron KM, Luber JM, Lowe MM, Huang L, Delaney C, Long JM, Fung ME, Newcomer K, Tsai KK, Chow M, Guinn S, Kuchroo JR, Burke KP, Schenkel JM, Rosenblum MD, Daud AI, Sharpe AH, Singer M. PMID: 33651880.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    5. Developing Human Skin Contains Lymphocytes Demonstrating a Memory Signature. Cell Rep Med. 2020 Nov 17; 1(8):100132. Dhariwala MO, Karthikeyan D, Vasquez KS, Farhat S, Weckel A, Taravati K, Leitner EG, Clancy S, Pauli M, Piper ML, Cohen JN, Ashouri JF, Lowe MM, Rosenblum MD, Scharschmidt TC. PMID: 33294857.
      View in: PubMed   Mentions:
    6. Immunopathogenesis of hidradenitis suppurativa and response to anti-TNF-α therapy. JCI Insight. 2020 10 02; 5(19). Lowe MM, Naik HB, Clancy S, Pauli M, Smith KM, Bi Y, Dunstan R, Gudjonsson JE, Paul M, Harris H, Kim E, Shin US, Ahn R, Liao W, Hansen SL, Rosenblum MD. PMID: 32841223.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    7. Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis. JCI Insight. 2020 10 02; 5(19). Gudjonsson JE, Tsoi LC, Ma F, Billi AC, van Straalen KR, Vossen ARJV, van der Zee HH, Harms PW, Wasikowski R, Yee CM, Rizvi SM, Xing X, Xing E, Plazyo O, Zeng C, Patrick MT, Lowe MM, Burney RE, Kozlow JH, Cherry-Bukowiec JR, Jiang Y, Kirma J, Weidinger S, Cushing KC, Rosenblum MD, Berthier C, MacLeod AS, Voorhees JJ, Wen F, Kahlenberg JM, Maverakis E, Modlin RL, Prens EP. PMID: 32853177.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    8. Layilin augments integrin activation to promote antitumor immunity. J Exp Med. 2020 09 07; 217(9). Mahuron KM, Moreau JM, Glasgow JE, Boda DP, Pauli ML, Gouirand V, Panjabi L, Grewal R, Luber JM, Mathur AN, Feldman RM, Shifrut E, Mehta P, Lowe MM, Alvarado MD, Marson A, Singer M, Wells J, Jupp R, Daud AI, Rosenblum MD. PMID: 32539073.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    9. Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues. JCI Insight. 2019 12 19; 4(24). Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, Arron ST, Neuhaus IM, Harris HW, Kim EA, Shin US, Krummel MF, Daud A, Scharschmidt TC, Rosenblum MD. PMID: 31852848.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    10. Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. Cell Host Microbe. 2019 12 11; 26(6):795-809.e5. Leech JM, Dhariwala MO, Lowe MM, Chu K, Merana GR, Cornuot C, Weckel A, Ma JM, Leitner EG, Gonzalez JR, Vasquez KS, Diep BA, Scharschmidt TC. PMID: 31784259.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    11. An Injectable Cytokine Trap for Local Treatment of Autoimmune Disease. Biomaterials. 2020 02; 230:119626. Zamecnik CR, Levy ES, Lowe MM, Zirak B, Rosenblum MD, Desai TA. PMID: 31753473.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. Regulatory T cells in skin are uniquely poised to suppress profibrotic immune responses. Sci Immunol. 2019 09 06; 4(39). Kalekar LA, Cohen JN, Prevel N, Sandoval PM, Mathur AN, Moreau JM, Lowe MM, Nosbaum A, Wolters PJ, Haemel A, Boin F, Rosenblum MD. PMID: 31492709.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    13. 868 Histologic progression of hidradenitis suppurativa: Implications for future therapeutic intervention. Journal of Investigative Dermatology. 2019 May 1; 139(5):s150. Salte SK, Todorovic TV, Wetter WJ, Scott SV, Smith SK, Lowe LM, Rosenblum RM, Gudjonsson GJ, Honore HP, Dunstan DR. .
      View in: Publisher Site   Mentions:
    14. Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair. Immunity. 2019 03 19; 50(3):655-667.e4. Mathur AN, Zirak B, Boothby IC, Tan M, Cohen JN, Mauro TM, Mehta P, Lowe MM, Abbas AK, Ali N, Rosenblum MD. PMID: 30893588.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    15. The TNFRSF members CD27 and OX40 coordinately limit TH17 differentiation in regulatory T cells. Sci Immunol. 2018 12 21; 3(30). Remedios KA, Zirak B, Sandoval PM, Lowe MM, Boda D, Henley E, Bhattrai S, Scharschmidt TC, Liao W, Naik HB, Rosenblum MD. PMID: 30578350.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    16. Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization. Microbiome. 2018 09 05; 6(1):154. Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W. PMID: 30185226.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    17. Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators. ACS Nano. 2017 11 28; 11(11):11433-11440. Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA. PMID: 29124929.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    18. Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation. Cell. 2017 Jun 01; 169(6):1119-1129.e11. Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD. PMID: 28552347.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    19. 041 Regulatory T cells drive stem cell differentiation during skin barrier repair. Journal of Investigative Dermatology. 2017 May 1; 137(5):s7. Mathur MA, Zirak ZB, Lowe LM, Abbas AA, Rosenblum RM. .
      View in: Publisher Site   Mentions:
    20. Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin. . 2017 Apr 12; 21(4):467-477.e5. Scharschmidt TC, Vasquez KS, Pauli ML, Leitner EG, Chu K, Truong HA, Lowe MM, Sanchez Rodriguez R, Ali N, Laszik ZG, Sonnenburg JL, Millar SE, Rosenblum MD. PMID: 28343820.
      View in: PubMed   Mentions:
    21. Relative mRNA Expression Levels of Restriction Factors and Antiviral Genes in Fetal and Adult Human Monocytes and Monocyte-Derived Macrophages. Viral Immunol. 2017 04; 30(3):142-148. Trang K, Raposo RA, Lowe MM, Krow-Lucal ER, Yonemoto W, Cabido VD, SenGupta D, McCune JM. PMID: 28151065.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production. PLoS One. 2014; 9(2):e87877. Lowe MM, Mold JE, Kanwar B, Huang Y, Louie A, Pollastri MP, Wang C, Patel G, Franks DG, Schlezinger J, Sherr DH, Silverstone AE, Hahn ME, McCune JM. PMID: 24498387.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    23. The catalytic subunit of human telomerase is a unique caspase-6 and caspase-7 substrate. Biochemistry. 2011 Oct 25; 50(42):9046-55. Soares J, Lowe MM, Jarstfer MB. PMID: 21936563.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    24. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med. 2010 May 19; 2(32):32ra36. Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. PMID: 20484731.
      View in: PubMed   Mentions: 249     Fields:    Translation:HumansCells
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