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Maria Telpoukhovskaia

Title(s)Postdoctoral Scholar, Gladstone Institutes
SchoolSchool of Medicine
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ORCID ORCID Icon0000-0002-5237-4042 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia. Sci Rep. 2020 Aug 13; 10(1):13688. Telpoukhovskaia MA, Liu K, Sayed FA, Etchegaray JI, Xie M, Zhan L, Li Y, Zhou Y, Le D, Bahr BA, Bogyo M, Ding S, Gan L. PMID: 32792571.
      View in: PubMed   Mentions:    Fields:    
    2. Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain. PLoS Biol. 2019 02; 17(2):e3000134. Zhan L, Krabbe G, Du F, Jones I, Reichert MC, Telpoukhovskaia M, Kodama L, Wang C, Cho SH, Sayed F, Li Y, Le D, Zhou Y, Shen Y, West B, Gan L. PMID: 30735499.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    3. Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):10172-10177. Sayed FA, Telpoukhovskaia M, Kodama L, Li Y, Zhou Y, Le D, Hauduc A, Ludwig C, Gao F, Clelland C, Zhan L, Cooper YA, Davalos D, Akassoglou K, Coppola G, Gan L. PMID: 30232263.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    4. Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases. Curr Opin Neurobiol. 2018 02; 48:52-58. Wang C, Telpoukhovskaia MA, Bahr BA, Chen X, Gan L. PMID: 29028540.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    5. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 2017 04 12; 9(385). Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ. PMID: 28404863.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    6. In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors. Bioorg Med Chem Lett. 2016 Mar 15; 26(6):1624-1628. Telpoukhovskaia MA, Patrick BO, Rodríguez-Rodríguez C, Orvig C. PMID: 26869193.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. 3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeability. Bioorg Med Chem Lett. 2015 Sep 01; 25(17):3654-7. Telpoukhovskaia MA, Cawthray JF, Rodríguez-Rodríguez C, Scott LE, Page BD, Patrick BO, Orvig C. PMID: 26141772.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models. Metallomics. 2015 Jan; 7(1):83-92. Rodríguez-Rodríguez C, Telpoukhovskaia MA, Alí-Torres J, Rodríguez-Santiago L, Manso Y, Bailey GA, Hidalgo J, Sodupe M, Orvig C. PMID: 25325557.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. 3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents. Metallomics. 2014 Feb; 6(2):249-62. Telpoukhovskaia MA, Rodríguez-Rodríguez C, Cawthray JF, Scott LE, Page BD, Alí-Torres J, Sodupe M, Bailey GA, Patrick BO, Orvig C. PMID: 23999879.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Synthesis, characterization, and cytotoxicity studies of Cu(II), Zn(II), and Fe(III) complexes of N-derivatized 3-hydroxy-4-pyridiones. J Inorg Biochem. 2014 Mar; 132:59-66. Telpoukhovskaia MA, Rodríguez-Rodríguez C, Scott LE, Page BD, Patrick BO, Orvig C. PMID: 24393377.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. ChemInform Abstract: Werner Coordination Chemistry and Neurodegeneration. ChemInform. 2013 Jul 16; 44(29):no-no. Maria A. Telpoukhovskaia, Chris Orvig. .
      View in: Publisher Site   Mentions:
    12. Exploring the multifunctionality of thioflavin- and deferiprone-based molecules as acetylcholinesterase inhibitors for potential application in Alzheimer's disease. Mol Biosyst. 2013 Apr 05; 9(4):792-805. Telpoukhovskaia MA, Patrick BO, Rodríguez-Rodríguez C, Orvig C. PMID: 23435553.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. The art of building multifunctional metal-binding agents from basic molecular scaffolds for the potential application in neurodegenerative diseases. Coordination Chemistry Reviews. 2012 Oct 1; 256(19-20):2308-2332. Cristina Rodríguez-Rodríguez, Maria Telpoukhovskaia, Chris Orvig. .
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    14. Werner coordination chemistry and neurodegeneration. Chem Soc Rev. 2013 Feb 21; 42(4):1836-46. Telpoukhovskaia MA, Orvig C. PMID: 22952002.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    15. N-Aryl -substituted 3-(ß-D-glucopyranosyloxy)-2-methyl-4(1 H )-pyridinones as agents for Alzheimer's therapy. Chemical Science. 2011 Jan 1; 2(4):642-648. Lauren E. Scott, Maria Telpoukhovskaia, Cristina Rodríguez-Rodríguez, Michael Merkel, Meryn L. Bowen, Brent D. G. Page, David E. Green, Tim Storr, Fancy Thomas, David D. Allen, Paul R. Lockman, Brian O. Patrick, Michael J. Adam, Chris Orvig. .
      View in: Publisher Site   Mentions:
    16. Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold. Bioorg Med Chem Lett. 2010 Apr 01; 20(7):2137-9. Tsou LK, Dutschman GE, Gullen EA, Telpoukhovskaia M, Cheng YC, Hamilton AD. PMID: 20202840.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
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