Maria Telpoukhovskaia

TitlePostdoctoral Scholar
InstitutionUniversity of California San Francisco
DepartmentGladstone Institutes
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    1. Wang C, Telpoukhovskaia M, Bahr BA, Chen X, Gan L. Endo-lysosomal dysfunction: a converging mechanism in neurodegenerative diseases. Curr Opin Neurobiol. 2018 Feb; 48:52-58. PMID: 29028540.
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    2. Ward ME, Chen R, Huang HY, Ludwig C, Telpoukhovskaia M, Taubes A, Boudin H, Minami SS, Reichert M, Albrecht P, Gelfand JM, Cruz-Herranz A, Cordano C, Alavi MV, Leslie S, Seeley WW, Miller BL, Bigio E, Mesulam MM, Bogyo MS, Mackenzie IR, Staropoli JF, Cotman SL, Huang EJ, Gan L, Green AJ. Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis. Sci Transl Med. 2017 04 12; 9(385). PMID: 28404863.
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    3. Telpoukhovskaia M, Patrick BO, Rodríguez-Rodríguez C, Orvig C. In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors. Bioorg Med Chem Lett. 2016 Mar 15; 26(6):1624-1628. PMID: 26869193.
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    4. Telpoukhovskaia M, Cawthray JF, Rodríguez-Rodríguez C, Scott LE, Page BD, Patrick BO, Orvig C. 3-Hydroxy-4-pyridinone derivatives designed for fluorescence studies to determine interaction with amyloid protein as well as cell permeability. Bioorg Med Chem Lett. 2015 Sep 01; 25(17):3654-7. PMID: 26141772.
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    5. Rodríguez-Rodríguez C, Telpoukhovskaia M, Alí-Torres J, Rodríguez-Santiago L, Manso Y, Bailey GA, Hidalgo J, Sodupe M, Orvig C. Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models. Metallomics. 2015 Jan; 7(1):83-92. PMID: 25325557.
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    6. Telpoukhovskaia M, Rodríguez-Rodríguez C, Cawthray JF, Scott LE, Page BD, Alí-Torres J, Sodupe M, Bailey GA, Patrick BO, Orvig C. 3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents. Metallomics. 2014 Feb; 6(2):249-62. PMID: 23999879.
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    7. Telpoukhovskaia M, Rodríguez-Rodríguez C, Scott LE, Page BD, Patrick BO, Orvig C. Synthesis, characterization, and cytotoxicity studies of Cu(II), Zn(II), and Fe(III) complexes of N-derivatized 3-hydroxy-4-pyridiones. J Inorg Biochem. 2014 Mar; 132:59-66. PMID: 24393377.
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    8. Telpoukhovskaia M, Patrick BO, Rodríguez-Rodríguez C, Orvig C. Exploring the multifunctionality of thioflavin- and deferiprone-based molecules as acetylcholinesterase inhibitors for potential application in Alzheimer's disease. Mol Biosyst. 2013 Apr 05; 9(4):792-805. PMID: 23435553.
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    9. Telpoukhovskaia M, Orvig C. Werner coordination chemistry and neurodegeneration. Chem Soc Rev. 2013 Feb 21; 42(4):1836-46. PMID: 22952002.
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    10. Tsou LK, Dutschman GE, Gullen EA, Telpoukhovskaia M, Cheng YC, Hamilton AD. Discovery of a synthetic dual inhibitor of HIV and HCV infection based on a tetrabutoxy-calix[4]arene scaffold. Bioorg Med Chem Lett. 2010 Apr 01; 20(7):2137-9. PMID: 20202840; PMCID: PMC2849157.
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