Marisa Medina, PhD

Title(s)Associate Professor, Pediatrics
SchoolSchool of Medicine
ORCID ORCID Icon0000-0002-3631-0129 Additional info
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    UC Davis, Davis, CAPhDGenetics
    Children's Hospital Oakland Research Institute, Oakland, CApostdoctoral fellowshipPharmacogenetics
    University of California, San Francisco03/2021Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines. BMC Genomics. 2020 Aug 12; 21(1):555. Theusch E, Chen YI, Rotter JI, Krauss RM, Medina MW. PMID: 32787775; PMCID: PMC7430882.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    2. Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation. Arterioscler Thromb Vasc Biol. 2020 05; 40(5):1311-1324. Qin Y, Ting F, Kim MJ, Strelnikov J, Harmon J, Gao F, Dose A, Teng BB, Alipour MA, Yao Z, Crooke R, Krauss RM, Medina MW. PMID: 32188273; PMCID: PMC7197750.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    3. The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. NPJ Genom Med. 2020; 5:1. Oni-Orisan A, Haldar T, Ranatunga DK, Medina MW, Schaefer C, Krauss RM, Iribarren C, Risch N, Hoffmann TJ. PMID: 31969989; PMCID: PMC6965183.
      View in: PubMed   Mentions: 7  
    4. GeneFishing to reconstruct context specific portraits of biological processes. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):18943-18950. Liu K, Theusch E, Zhou Y, Ashuach T, Dose AC, Bickel PJ, Medina MW, Huang H. PMID: 31484776; PMCID: PMC6754596.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. Stem Cell Res. 2019 05; 37:101434. Kuang YL, Munoz A, Nalula G, Santostefano KE, Sanghez V, Sanchez G, Terada N, Mattis AN, Iacovino M, Iribarren C, Krauss RM, Medina MW. PMID: 30999275; PMCID: PMC6570500.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    6. Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort. Circ Genom Precis Med. 2018 09; 11(9):e002043. Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N. PMID: 30354326; PMCID: PMC6214660.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    7. ZNF542P is a pseudogene associated with LDL response to simvastatin treatment. Sci Rep. 2018 08 20; 8(1):12443. Kim K, Theusch E, Kuang YL, Dose A, Mitchel K, Cubitt C, Chen YI, Krauss RM, Medina MW. PMID: 30127457; PMCID: PMC6102286.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    8. A large electronic-health-record-based genome-wide study of serum lipids. Nat Genet. 2018 03; 50(3):401-413. Hoffmann TJ, Theusch E, Haldar T, Ranatunga DK, Jorgenson E, Medina MW, Kvale MN, Kwok PY, Schaefer C, Krauss RM, Iribarren C, Risch N. PMID: 29507422; PMCID: PMC5942247.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    9. Generalized correlation measure using count statistics for gene expression data with ordered samples. Bioinformatics. 2018 02 15; 34(4):617-624. Wang YXR, Liu K, Theusch E, Rotter JI, Medina MW, Waterman MS, Huang H, Stegle O. PMID: 29040382; PMCID: PMC5860612.
      View in: PubMed   Mentions: 5     Fields:    
    10. Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. Proc Natl Acad Sci U S A. 2017 09 12; 114(37):E7746-E7755. Alvarez MI, Glover LC, Luo P, Wang L, Theusch E, Oehlers SH, Walton EM, Tram TTB, Kuang YL, Rotter JI, McClean CM, Chinh NT, Medina MW, Tobin DM, Dunstan SJ, Ko DC. PMID: 28827342; PMCID: PMC5604016.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    11. SUGP1 is a novel regulator of cholesterol metabolism. Hum Mol Genet. 2016 07 15; 25(14):3106-3116. Kim MJ, Yu CY, Theusch E, Naidoo D, Stevens K, Kuang YL, Schuetz E, Chaudhry AS, Medina MW. PMID: 27206982; PMCID: PMC5181593.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol. Circ Cardiovasc Genet. 2016 Jun; 9(3):223-30. Mitchel K, Theusch E, Cubitt C, Dosé AC, Stevens K, Naidoo D, Medina MW. PMID: 27071970; PMCID: PMC4917428.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. Individual and Combined Associations of Genetic Variants in CYP3A4, CYP3A5, and SLCO1B1 With Simvastatin and Simvastatin Acid Plasma Concentrations. J Cardiovasc Pharmacol. 2015 Jul; 66(1):80-5. Luzum JA, Theusch E, Taylor KD, Wang A, Sadee W, Binkley PF, Krauss RM, Medina MW, Kitzmiller JP. PMID: 26164721; PMCID: PMC4503374.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    14. GATM polymorphism associated with the risk for statin-induced myopathy does not replicate in case-control analysis of 715 dyslipidemic individuals. Cell Metab. 2015 Apr 07; 21(4):622-7. Luzum JA, Kitzmiller JP, Isackson PJ, Ma C, Medina MW, Dauki AM, Mikulik EB, Ochs-Balcom HM, Vladutiu GD. PMID: 25863251; PMCID: PMC4394188.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    15. CYP3A4*22 and CYP3A5*3 are associated with increased levels of plasma simvastatin concentrations in the cholesterol and pharmacogenetics study cohort. Pharmacogenet Genomics. 2014 Oct; 24(10):486-91. Kitzmiller JP, Luzum JA, Baldassarre D, Krauss RM, Medina MW. PMID: 25051018; PMCID: PMC4160394.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCellsCTClinical Trials
    16. Ancestry and other genetic associations with plasma PCSK9 response to simvastatin. Pharmacogenet Genomics. 2014 Oct; 24(10):492-500. Theusch E, Medina MW, Rotter JI, Krauss RM. PMID: 25089948; PMCID: PMC4159722.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    17. Prediction of LDL cholesterol response to statin using transcriptomic and genetic variation. Genome Biol. 2014 Sep 30; 15(9):460. Kim K, Bolotin E, Theusch E, Huang H, Medina MW, Krauss RM. PMID: 25316374; PMCID: PMC4180544.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    18. Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):1917-23. Medina MW, Bauzon F, Naidoo D, Theusch E, Stevens K, Schilde J, Schubert C, Mangravite LM, Rudel LL, Temel RE, Runz H, Krauss RM. PMID: 25035345; PMCID: PMC4141484.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    19. Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines. Pharmacogenomics. 2014 Feb; 15(2):137-46. Brown CC, Havener TM, Medina MW, Jack JR, Krauss RM, McLeod HL, Motsinger-Reif AA. PMID: 24444404; PMCID: PMC4055088.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    20. Statin-induced changes in gene expression in EBV-transformed and native B-cells. Hum Mol Genet. 2014 Mar 01; 23(5):1202-10. Bolotin E, Armendariz A, Kim K, Heo SJ, Boffelli D, Tantisira K, Rotter JI, Krauss RM, Medina MW. PMID: 24179175; PMCID: PMC3919007.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    21. HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism. Hum Mol Genet. 2014 Jan 15; 23(2):319-32. Yu CY, Theusch E, Lo K, Mangravite LM, Naidoo D, Kutilova M, Medina MW. PMID: 24001602; PMCID: PMC3869353.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    22. A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. Nature. 2013 Oct 17; 502(7471):377-80. Mangravite LM, Engelhardt BE, Medina MW, Smith JD, Brown CD, Chasman DI, Mecham BH, Howie B, Shim H, Naidoo D, Feng Q, Rieder MJ, Chen YD, Rotter JI, Ridker PM, Hopewell JC, Parish S, Armitage J, Collins R, Wilke RA, Nickerson DA, Stephens M, Krauss RM. PMID: 23995691; PMCID: PMC3933266.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansCells
    23. Alternative splicing in the regulation of cholesterol homeostasis. Curr Opin Lipidol. 2013 Apr; 24(2):147-52. Medina MW, Krauss RM. PMID: 23314925; PMCID: PMC3667406.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    24. A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function. Hum Mol Genet. 2013 Apr 01; 22(7):1424-31. Gao F, Ihn HE, Medina MW, Krauss RM. PMID: 23297366; PMCID: PMC3596853.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    25. ATHENA: a tool for meta-dimensional analysis applied to genotypes and gene expression data to predict HDL cholesterol levels. Pac Symp Biocomput. 2013; 385-96. Holzinger ER, Dudek SM, Frase AT, Krauss RM, Medina MW, Ritchie MD. PMID: 23424143; PMCID: PMC3587764.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    26. RHOA is a modulator of the cholesterol-lowering effects of statin. PLoS Genet. 2012; 8(11):e1003058. Medina MW, Theusch E, Naidoo D, Bauzon F, Stevens K, Mangravite LM, Kuang YL, Krauss RM. PMID: 23166513; PMCID: PMC3499361.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    27. A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT. Pharmacogenet Genomics. 2012 Nov; 22(11):796-802. Brown CC, Havener TM, Medina MW, Auman JT, Mangravite LM, Krauss RM, McLeod HL, Motsinger-Reif AA. PMID: 23047291; PMCID: PMC3691078.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    28. Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment. Circulation. 2008 Mar 25; 117(12):1537-44. Krauss RM, Mangravite LM, Smith JD, Medina MW, Wang D, Guo X, Rieder MJ, Simon JA, Hulley SB, Waters D, Saad M, Williams PT, Taylor KD, Yang H, Nickerson DA, Rotter JI. PMID: 18332269.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
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