Loading...

Marlene Grenon, MD

Title(s)Assoc Professor in Residence, Surgery
SchoolSchool of Medicine
Phone415-750-2115
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Effects of fish oil on inflammation and vascular function in claudicants
    NIH/NHLBI K23HL122446May 1, 2014 - Apr 30, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse In The News
    Collapse Student Projects
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Ramirez JL, Zahner GJ, Spaulding KA, Khetani SA, Hills NK, Gasper WJ, Harris WS, Cohen BE, Grenon SM. Peripheral Artery Disease Is Associated with a Deficiency of Erythrocyte Membrane n-3 Polyunsaturated Fatty Acids. Lipids. 2019 Mar 18. PMID: 30883776.
      View in: PubMed
    2. Ramirez JL, Gasper WJ, Khetani SA, Zahner GJ, Hills NK, Mitchell PT, Sansbury BE, Conte MS, Spite M, Grenon SM. Fish Oil Increases Specialized Pro-resolving Lipid Mediators in PAD (The OMEGA-PAD II Trial). J Surg Res. 2019 Feb 13; 238:164-174. PMID: 30771686.
      View in: PubMed
    3. Zahner GJ, Ramirez JL, Spaulding KA, Khetani SA, Gasper WJ, Grunfeld C, Hills NK, Schafer AL, Grenon SM. Leptinemia is Associated With Peripheral Artery Disease. J Surg Res. 2019 Feb 06; 238:48-56. PMID: 30738358.
      View in: PubMed
    4. Drudi LM, Ades M, Landry T, Gill HL, Grenon SM, Steinmetz OK, Afilalo J. Scoping review of frailty in vascular surgery. J Vasc Surg. 2018 Dec 24. PMID: 30591292.
      View in: PubMed
    5. Ramirez JL, Khetani SA, Zahner GJ, Spaulding KA, Schaller MS, Gasper WJ, Hills NK, Schafer AL, Grenon SM. Serum resistin is associated with impaired endothelial function and a higher rate of adverse cardiac events in patients with peripheral artery disease. J Vasc Surg. 2018 Oct 03. PMID: 30292618.
      View in: PubMed
    6. Ramirez JL, Grenon SM. Depression and peripheral artery disease: why we should care and what we can do. CVIR Endovasc. 2018; 1(1):14. PMID: 30652146.
      View in: PubMed
    7. Hernandez NV, Ramirez JL, Khetani SA, Spaulding KA, Gasper WJ, Hiramoto J, Lindqvist D, Wolkowitz OM, Hills NK, Grenon SM, Zahner GJ. Depression severity is associated with increased inflammation in veterans with peripheral artery disease. Vasc Med. 2018 10; 23(5):445-453. PMID: 30035700.
      View in: PubMed
    8. Ramirez JL, Drudi LM, Grenon SM. Review of biologic and behavioral risk factors linking depression and peripheral artery disease. Vasc Med. 2018 10; 23(5):478-488. PMID: 29801423.
      View in: PubMed
    9. Schaller MS, Ramirez JL, Gasper WJ, Zahner GJ, Hills NK, Grenon SM. Frailty Is Associated with an Increased Risk of Major Adverse Cardiac Events in Patients with Stable Claudication. Ann Vasc Surg. 2018 Jul; 50:38-45. PMID: 29477684.
      View in: PubMed
    10. Arya S, Lee S, Zahner GJ, Cohen BE, Hiramoto J, Wolkowitz OM, Khakharia A, Binney ZO, Grenon SM. The association of comorbid depression with mortality and amputation in veterans with peripheral artery disease. J Vasc Surg. 2018 08; 68(2):536-545.e2. PMID: 29588133.
      View in: PubMed
    11. Zahner GJ, Spaulding KA, Ramirez JL, Schaller MS, Walker SC, Hills NK, Gasper WJ, Grenon SM. Characterizing the relationship between flow-mediated vasodilation and radial artery tonometry in peripheral artery disease. J Surg Res. 2018 Apr; 224:121-131. PMID: 29506827.
      View in: PubMed
    12. Lindqvist D, Mellon SH, Dhabhar FS, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Aschbacher K, Bersani FS, Marmar CR, Wolkowitz OM. Increased circulating blood cell counts in combat-related PTSD: Associations with inflammation and PTSD severity. Psychiatry Res. 2017 12; 258:330-336. PMID: 28942957.
      View in: PubMed
    13. Zahner GJ, Gruendl MA, Spaulding KA, Schaller MS, Hills NK, Gasper WJ, Grenon SM. Association between arterial stiffness and peripheral artery disease as measured by radial artery tonometry. J Vasc Surg. 2017 11; 66(5):1518-1526. PMID: 28756044.
      View in: PubMed
    14. Schaller MS, Zahner GJ, Gasper WJ, Harris WS, Conte MS, Hills NK, Grenon SM. Relationship between the omega-3 index and specialized pro-resolving lipid mediators in patients with peripheral arterial disease taking fish oil supplements. J Clin Lipidol. 2017 Sep - Oct; 11(5):1289-1295. PMID: 28778393.
      View in: PubMed
    15. Drudi LM, Schaller MS, Hiramoto J, Gasper W, Harris WS, Hills NK, Grenon SM. Predictors of change in omega-3 index with fish oil supplementation in peripheral artery disease. J Surg Res. 2017 04; 210:124-131. PMID: 28457318.
      View in: PubMed
    16. Lindqvist D, Dhabhar FS, Mellon SH, Yehuda R, Grenon SM, Flory JD, Bierer LM, Abu-Amara D, Coy M, Makotkine I, Reus VI, Bersani FS, Marmar CR, Wolkowitz OM. Increased pro-inflammatory milieu in combat related PTSD - A new cohort replication study. Brain Behav Immun. 2017 Jan; 59:260-264. PMID: 27638184.
      View in: PubMed
    17. Aschbacher K, Milush JM, Gilbert A, Almeida C, Sinclair E, Epling L, Grenon SM, Marco EJ, Puterman E, Epel E. Chronic stress is associated with reduced circulating hematopoietic progenitor cell number: A maternal caregiving model. Brain Behav Immun. 2017 Jan; 59:245-252. PMID: 27622676.
      View in: PubMed
    18. Grenon SM, Owens CD, Alley H, Perez S, Whooley MA, Neylan TC, Aschbacher K, Gasper WJ, Hilton JF, Cohen BE. Posttraumatic Stress Disorder Is Associated With Worse Endothelial Function Among Veterans. J Am Heart Assoc. 2016 Mar 23; 5(3):e003010. PMID: 27009621; PMCID: PMC4943274.
      View in: PubMed, PubMed Central
    19. Grenon SM, Owens CD, Nosova EV, Hughes-Fulford M, Alley HF, Chong K, Perez S, Yen PK, Boscardin J, Hellmann J, Spite M, Conte MS. Short-Term, High-Dose Fish Oil Supplementation Increases the Production of Omega-3 Fatty Acid-Derived Mediators in Patients With Peripheral Artery Disease (the OMEGA-PAD I Trial). J Am Heart Assoc. 2015 Aug 21; 4(8):e002034. PMID: 26296857; PMCID: PMC4599461.
      View in: PubMed, PubMed Central
    20. Itoga NK, Woo K, Bismuth J, Bechara CF, Grenon M, Mitchell E, Zhou W. A Rising Generation of Diversity in the Vascular Surgery Workforce. Ann Vasc Surg. 2015 Oct; 29(7):1484-6. PMID: 26253044.
      View in: PubMed
    21. Nosova EV, Bartel K, Chong KC, Alley HF, Conte MS, Owens CD, Grenon SM. Analysis of nutritional habits and intake of polyunsaturated fatty acids in veterans with peripheral arterial disease. Vasc Med. 2015 Oct; 20(5):432-8. PMID: 26129736.
      View in: PubMed
    22. Chang TT, Spurlock SM, Candelario TL, Grenon SM, Hughes-Fulford M. Spaceflight impairs antigen-specific tolerance induction in vivo and increases inflammatory cytokines. FASEB J. 2015 Oct; 29(10):4122-32. PMID: 26085131.
      View in: PubMed
    23. Nosova EV, Conte MS, Grenon SM. Advancing beyond the "heart-healthy diet" for peripheral arterial disease. J Vasc Surg. 2015 Jan; 61(1):265-74. PMID: 25534981; PMCID: PMC4275620.
      View in: PubMed, PubMed Central
    24. Alley H, Owens CD, Gasper WJ, Grenon SM. Ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery in clinical research. J Vis Exp. 2014 Oct 22; (92):e52070. PMID: 25406739; PMCID: PMC4353419.
      View in: PubMed, PubMed Central
    25. Chong KC, Owens CD, Park M, Alley HF, Boscardin WJ, Conte MS, Gasper WJ, Grenon SM. Relationship between kidney disease and endothelial function in peripheral artery disease. J Vasc Surg. 2014 Dec; 60(6):1605-11. PMID: 25441679; PMCID: PMC4254442.
      View in: PubMed, PubMed Central
    26. Walker JP, Nosova E, Sigovan M, Rapp J, Grenon MS, Owens CD, Gasper WJ, Saloner DA. Ferumoxytol-enhanced magnetic resonance angiography is a feasible method for the clinical evaluation of lower extremity arterial disease. Ann Vasc Surg. 2015 Jan; 29(1):63-8. PMID: 25269682.
      View in: PubMed
    27. Nosova EV, Chong KC, Alley HF, Harris WS, Boscardin WJ, Conte MS, Owens CD, Grenon SM. Clinical correlates of red blood cell omega-3 fatty acid content in male veterans with peripheral arterial disease. J Vasc Surg. 2014 Nov; 60(5):1325-1331. PMID: 24953895.
      View in: PubMed
    28. Drudi L, Grenon SM. Women's health in spaceflight. Aviat Space Environ Med. 2014 Jun; 85(6):645-52. PMID: 24919386.
      View in: PubMed
    29. Grenon SM, Cohen BE, Smolderen K, Vittinghoff E, Whooley MA, Hiramoto J. Peripheral arterial disease, gender, and depression in the Heart and Soul Study. J Vasc Surg. 2014 Aug; 60(2):396-403. PMID: 24661811; PMCID: PMC4199228.
      View in: PubMed, PubMed Central
    30. Nosova EV, Yen P, Chong KC, Alley HF, Stock EO, Quinn A, Hellmann J, Conte MS, Owens CD, Spite M, Grenon SM. Short-term physical inactivity impairs vascular function. J Surg Res. 2014 Aug; 190(2):672-82. PMID: 24630521; PMCID: PMC4096607.
      View in: PubMed, PubMed Central
    31. Grenon SM, Chong K, Alley H, Nosova E, Gasper W, Hiramoto J, Boscardin WJ, Owens CD. Walking disability in patients with peripheral artery disease is associated with arterial endothelial function. J Vasc Surg. 2014 Apr; 59(4):1025-34. PMID: 24423479; PMCID: PMC3966931.
      View in: PubMed, PubMed Central
    32. Owens CD, Gasper WJ, Walker JP, Alley HF, Conte MS, Grenon SM. Safety and feasibility of adjunctive dexamethasone infusion into the adventitia of the femoropopliteal artery following endovascular revascularization. J Vasc Surg. 2014 Apr; 59(4):1016-24. PMID: 24423476; PMCID: PMC4391811.
      View in: PubMed, PubMed Central
    33. Grenon SM, Conte MS.n-3 polyunsaturated fatty acids to heal the broken heart. Clinical Lipidology. 2013; 8(5):497-500.
    34. Grenon SM, Owens CD, Alley H, Chong K, Yen PK, Harris W, Hughes-Fulford M, Conte MS. n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial. Vasc Med. 2013 Oct; 18(5):263-74. PMID: 24052491; PMCID: PMC4074651.
      View in: PubMed, PubMed Central
    35. Grenon SM, Vittinghoff E, Owens CD, Conte MS, Whooley M, Cohen BE. Peripheral artery disease and risk of cardiovascular events in patients with coronary artery disease: insights from the Heart and Soul Study. Vasc Med. 2013 Aug; 18(4):176-84. PMID: 23835937; PMCID: PMC4207208.
      View in: PubMed, PubMed Central
    36. Grenon SM, Conte MS, Nosova E, Alley H, Chong K, Harris WS, Vittinghoff E, Owens CD. Association between n-3 polyunsaturated fatty acid content of red blood cells and inflammatory biomarkers in patients with peripheral artery disease. J Vasc Surg. 2013 Nov; 58(5):1283-90. PMID: 23830313; PMCID: PMC4207080.
      View in: PubMed, PubMed Central
    37. Gasper WJ, Reilly LM, Rapp JH, Grenon SM, Hiramoto JS, Sobel JD, Chuter TA. Assessing the anatomic applicability of the multibranched endovascular repair of thoracoabdominal aortic aneurysm technique. J Vasc Surg. 2013 Jun; 57(6):1553-8; discussion 1558. PMID: 23395201.
      View in: PubMed
    38. Grenon SM, Jeanne M, Aguado-Zuniga J, Conte MS, Hughes-Fulford M. Effects of gravitational mechanical unloading in endothelial cells: association between caveolins, inflammation and adhesion molecules. Sci Rep. 2013; 3:1494. PMID: 23511048; PMCID: PMC3603133.
      View in: PubMed, PubMed Central
    39. Grenon SM, Saary J, Gray G, Vanderploeg JM, Hughes-Fulford M. Can I take a space flight? Considerations for doctors. BMJ. 2012 Dec 13; 345:e8124. PMID: 23241271; PMCID: PMC4688424.
      View in: PubMed, PubMed Central
    40. S. Marlene Grenon, Chad Ball, Joan Saary and Andy W. Kirkpatrick. Surgery in Space. Editors J Wong and J Pelton. LAP Lambert Academic Publishing. ISBN 978-3-659-26581-5.2012.
    41. Grenon SM, Cohen BE.J Am Heart Assoc. (published online August 30th 2012). In response to: "Low serum 25-hydroxyvitamin D concentrations may explain the link between depression and peripheral artery disease". 2012.
    42. Grenon SM, Hiramoto J, Smolderen KG, Vittinghoff E, Whooley MA, Cohen BE. Association between depression and peripheral artery disease: insights from the heart and soul study. J Am Heart Assoc. 2012 Aug; 1(4):e002667. PMID: 23130170; PMCID: PMC3487348.
      View in: PubMed, PubMed Central
    43. Reilly LM, Rapp JH, Grenon SM, Hiramoto JS, Sobel J, Chuter TA. Efficacy and durability of endovascular thoracoabdominal aortic aneurysm repair using the caudally directed cuff technique. J Vasc Surg. 2012 Jul; 56(1):53-63; discussion 63-4. PMID: 22560233.
      View in: PubMed
    44. Grenon SM, Aguado-Zuniga J, Hatton JP, Owens CD, Conte MS, Hughes-Fulford M. Effects of fatty acids on endothelial cells: inflammation and monocyte adhesion. J Surg Res. 2012 Sep; 177(1):e35-43. PMID: 22572621; PMCID: PMC3756552.
      View in: PubMed, PubMed Central
    45. Grenon SM, Hughes-Fulford M, Rapp J, Conte MS. Polyunsaturated fatty acids and peripheral artery disease. Vasc Med. 2012 Feb; 17(1):51-63. PMID: 22363018.
      View in: PubMed
    46. Drudi L, Ball CG, Kirkpatrick AW, Saary J, Grenon SM. Surgery in Space: Where are we at now? Acta Astronaut. 2012; 79:61-66. PMID: 23990690.
      View in: PubMed
    47. Grenon SM, Saary J. Challenges in aerospace medicine education. Aviat Space Environ Med. 2011 Nov; 82(11):1071-2. PMID: 22097645.
      View in: PubMed
    48. Grenon SM, Reid JD, Clement J. A late complication of migration after aortic endografting: injury to the superior mesenteric artery. J Vasc Interv Radiol. 2011 Jul; 22(7):1055-7. PMID: 21708328.
      View in: PubMed
    49. Grenon SM, Reilly LM, Ramaiah VG. Technical endovascular highlights for crossing the difficult aortic bifurcation. J Vasc Surg. 2011 Sep; 54(3):893-6. PMID: 21664094.
      View in: PubMed
    50. Grenon SM, Conte MS. Aspirin prophylaxis (100 mg daily) does not improve cardiovascular outcomes compared to placebo in asymptomatic individuals with incidental low-ankle brachial index. Evid Based Med. 2010 Aug; 15(4):106-8. PMID: 20530607.
      View in: PubMed
    51. Kirkpatrick AW, Keaney MA, Bentz K, Groleau M, Tyssen M, Keyte J, Ball CG, Campbell MR, Grenon SM, McBeth P, Broderick TJ. .The use of the National Research Council of Canada's Falcon 20 research aircraft as a terrestrial analogue space environment (TASE) for space surgery research: Challenges and suggested solutions. Planetary and Space Science 58, 717-723,. 2010.
    52. Grenon SM, Gagnon J, Hsiang Y, Sidhu R, Taylor D, Clement J, Chen J. Occlusion of the common and internal iliac arteries for aortoiliac aneurysm repair: experience with the Amplatzer vascular plug. Can J Surg. 2009 Dec; 52(6):E276-80. PMID: 20011164; PMCID: PMC2792393.
      View in: PubMed, PubMed Central
    53. Grenon SM, Gagnon J, Hsiang Y. Video in clinical medicine. Ankle-brachial index for assessment of peripheral arterial disease. N Engl J Med. 2009 Nov 05; 361(19):e40. PMID: 19890121.
      View in: PubMed
    54. Grenon SM, Gagnon J, Hsiang YN, Chen JC. Canadian experience with percutaneous endovascular aneurysm repair: short-term outcomes. Can J Surg. 2009 Oct; 52(5):E156-60. PMID: 19865546; PMCID: PMC2769107.
      View in: PubMed, PubMed Central
    55. Grenon SM, Mateus J, Hsiang Y, Sidhu R, Young L, Gagnon J. Use of short-radius centrifugation to augment ankle-brachial indices. J Investig Med. 2009 Jun; 57(5):640-4. PMID: 19491627.
      View in: PubMed
    56. MacDonald S, Cheung A, Sidhu R, Rheaume P, Grenon SM, Clement J. Endovascular aortic aneurysm repair via the left ventricular apex of a beating heart. J Vasc Surg. 2009 Mar; 49(3):759-62. PMID: 19268778.
      View in: PubMed
    57. Grenon SM, MacDonald S, Sidhu RS, Reid JD, Cheung A, Hsiang Y, Clement J. Successful ventricular transapical thoracic endovascular graft deployment in a pig model. J Vasc Surg. 2008 Nov; 48(5):1301-5. PMID: 18771890.
      View in: PubMed
    58. Grushka JR, Grenon SM, Ferri LE. A type IV paraesophageal hernia containing a volvulized sigmoid colon. Dis Esophagus. 2008; 21(1):94-6. PMID: 18197947.
      View in: PubMed
    59. Grenon SM, Lachapelle K, Marcil M, Omeroglu A, Genest J, de Varennes B. Surgical strategies for severe calcification of the aorta (porcelain aorta) in two patients with homozygous familial hypercholesterolemia. Can J Cardiol. 2007 Dec; 23(14):1159-61. PMID: 18060104; PMCID: PMC2652009.
      View in: PubMed, PubMed Central
    60. Bernier PL, Grenon M, Ergina P, Schricker T, Chaudhury P, Metrakos P, Lachapelle K. Combined simultaneous heart and liver transplantation with complete cardiopulmonary bypass support. Ann Thorac Surg. 2007 Apr; 83(4):1544-5. PMID: 17383383.
      View in: PubMed
    61. Grenon SM, Xiao X, Hurwitz S, Sheynberg N, Kim C, Seely EW, Cohen RJ, Williams GH. Why is orthostatic tolerance lower in women than in men? Renal and cardiovascular responses to simulated microgravity and the role of midodrine. J Investig Med. 2006 May; 54(4):180-90. PMID: 17152857.
      View in: PubMed
    62. Xiao X, Grenon SM, Kim C, Sheynberg N, Hurwitz S, Williams GH, Cohen RJ. Bed rest effects on human calf hemodynamics and orthostatic intolerance: a model-based analysis. Aviat Space Environ Med. 2005 Nov; 76(11):1037-45. PMID: 16315396.
      View in: PubMed
    63. Grenon SM, Xiao X, Hurwitz S, Ramsdell CD, Sheynberg N, Kim C, Williams GH, Cohen RJ. Simulated microgravity induces microvolt T wave alternans. Ann Noninvasive Electrocardiol. 2005 Jul; 10(3):363-70. PMID: 16029389.
      View in: PubMed
    64. Grenon SM, Hurwitz S, Xiao X, Sheynberg N, Ramsdell CD, Kim C, Cohen RJ, Williams GH. Readaptation from simulated microgravity as a stimulus for improved orthostatic tolerance: role of the renal, cardioendocrine, and cardiovascular systems. J Investig Med. 2005 Mar; 53(2):82-91. PMID: 15810494.
      View in: PubMed
    65. Grenon SM, Hurwitz S, Sheynberg N, Xiao X, Judson B, Ramsdell CD, Kim C, Cohen RJ, Williams GH. Sleep restriction does not affect orthostatic tolerance in the simulated microgravity environment. J Appl Physiol (1985). 2004 Nov; 97(5):1660-6. PMID: 15234956.
      View in: PubMed
    66. Grenon SM, Hurwitz S, Sheynberg N, Xiao X, Ramsdell CD, Mai CL, Kim C, Cohen RJ, Williams GH. Role of individual predisposition in orthostatic intolerance before and after simulated microgravity. J Appl Physiol (1985). 2004 May; 96(5):1714-22. PMID: 15075309.
      View in: PubMed
    67. Grenon SM, Sheynberg N, Hurwitz S, Xiao G, Ramsdell CD, Ehrman MD, Mai CL, Kristjansson SR, Sundby GH, Cohen RJ, Williams GH. Renal, endocrine, and cardiovascular responses to bed rest in male subjects on a constant diet. J Investig Med. 2004 Mar; 52(2):117-28. PMID: 15068228.
      View in: PubMed
    68. Xiao X, Mukkamala R, Sheynberg N, Grenon SM, Ehrman MD, Mullen TJ, Ramsdell CD, Williams GH, Cohen RJ. Effects of simulated microgravity on closed-loop cardiovascular regulation and orthostatic intolerance: analysis by means of system identification. J Appl Physiol (1985). 2004 Feb; 96(2):489-97. PMID: 14514703.
      View in: PubMed
    69. Campbell J, Grenon M, You CK. Psuedoaneurysm of the superficial femoral artery resulting from stingray envenomation. Ann Vasc Surg. 2003 Mar; 17(2):217-20. PMID: 12616364.
      View in: PubMed
    Marlene's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (324) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (30) people
    _
    Similar People
    People who share similar concepts with this person.
    See all (60) people
    _
    Same Department
    Search Department
    ↑