Masanori Funabashi, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Pharmacy
Address1700 4th Street
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA. Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases. Cell. 2017 Jan 26; 168(3):517-526.e18. PMID: 28111075.
      View in: PubMed
    2. Liu X, Jin Y, Cai W, Green KD, Goswami A, Garneau-Tsodikova S, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW. Org Biomol Chem. 2016 Apr 28; 14(16):3956-62. PMID: 27050157.
      View in: PubMed
    3. Liu X, Jin Y, Cui Z, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. The Role of a Nonribosomal Peptide Synthetase in l-Lysine Lactamization During Capuramycin Biosynthesis. Chembiochem. 2016 May 3; 17(9):804-10. PMID: 26840634.
      View in: PubMed
    4. Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. J Biol Chem. 2015 May 29; 290(22):13710-24. PMID: 25855790; PMCID: PMC4447950 [Available on 05/29/16].
    5. Funabashi M, Baba S, Takatsu T, Kizuka M, Ohata Y, Tanaka M, Nonaka K, Spork AP, Ducho C, Chen WC, Van Lanen SG. Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor. Angew Chem Int Ed Engl. 2013 Oct 25; 52(44):11607-11. PMID: 24014169; PMCID: PMC3873198.
    6. Chi X, Baba S, Tibrewal N, Funabashi M, Nonaka K, Van Lanen SG. The muraminomicin biosynthetic gene cluster and enzymatic formation of the 2-deoxyaminoribosyl appendage. Medchemcomm. 2013 Jan 1; 4(1):239-243. PMID: 23476724.
      View in: PubMed
    7. Fujita Y, Kizuka M, Funabashi M, Ogawa Y, Ishikawa T, Nonaka K, Takatsu T. A-90289 A and B, new inhibitors of bacterial translocase I, produced by Streptomyces sp. SANK 60405. J Antibiot (Tokyo). 2011 Jul; 64(7):495-501. PMID: 21587261.
      View in: PubMed
    8. Yang Z, Chi X, Funabashi M, Baba S, Nonaka K, Pahari P, Unrine J, Jacobsen JM, Elliott GI, Rohr J, Van Lanen SG. Characterization of LipL as a non-heme, Fe(II)-dependent a-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. J Biol Chem. 2011 Mar 11; 286(10):7885-92. PMID: 21216959; PMCID: PMC3048675.
    9. Funabashi M, Yang Z, Nonaka K, Hosobuchi M, Fujita Y, Shibata T, Chi X, Van Lanen SG. An ATP-independent strategy for amide bond formation in antibiotic biosynthesis. Nat Chem Biol. 2010 Aug; 6(8):581-6. PMID: 20562876.
      View in: PubMed
    10. Yang Z, Funabashi M, Nonaka K, Hosobuchi M, Shibata T, Pahari P, Van Lanen SG. Functional and kinetic analysis of the phosphotransferase CapP conferring selective self-resistance to capuramycin antibiotics. J Biol Chem. 2010 Apr 23; 285(17):12899-905. PMID: 20202936; PMCID: PMC2857116.
    11. Funabashi M, Baba S, Nonaka K, Hosobuchi M, Fujita Y, Shibata T, Van Lanen SG. The biosynthesis of liposidomycin-like A-90289 antibiotics featuring a new type of sulfotransferase. Chembiochem. 2010 Jan 25; 11(2):184-90. PMID: 20043306.
      View in: PubMed
    12. Funabashi M, Nonaka K, Yada C, Hosobuchi M, Masuda N, Shibata T, Van Lanen SG. Identification of the biosynthetic gene cluster of A-500359s in Streptomyces griseus SANK60196. J Antibiot (Tokyo). 2009 Jun; 62(6):325-32. PMID: 19478828.
      View in: PubMed
    13. Funabashi M, Funa N, Horinouchi S. Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus. J Biol Chem. 2008 May 16; 283(20):13983-91. PMID: 18364359.
      View in: PubMed
    14. Funa N, Funabashi M, Ohnishi Y, Horinouchi S. Biosynthesis of hexahydroxyperylenequinone melanin via oxidative aryl coupling by cytochrome P-450 in Streptomyces griseus. J Bacteriol. 2005 Dec; 187(23):8149-55. PMID: 16291687; PMCID: PMC1291289.
    15. Funa N, Funabashi M, Yoshimura E, Horinouchi S. A novel quinone-forming monooxygenase family involved in modification of aromatic polyketides. J Biol Chem. 2005 Apr 15; 280(15):14514-23. PMID: 15701630.
      View in: PubMed
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