Matthew Gruner, PhD

Title(s)Postdoctoral Scholar, Cell and Tissue Biology
SchoolSchool of Dentistry
Address513 Parnassus Ave, HSW
San Francisco CA 94143
ORCID ORCID Icon0000-0001-5175-4177 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of Nevada, Reno, Reno, NVPhD2017Cell Molecular Biology

    Collapse Overview 
    Collapse Overview
    I am interested in understanding what RNA can tell us about how cells work and what happens during disease. Many RNAs are transcribed and not translated into protein but rather regulate protein production. Recently circRNAs were shown to regulate cell division during development and cancer via interactions with microRNAs, transcription factors and RNA binding proteins. As a PhD student at the University of Nevada in Reno I helped identify new circRNAs in the nematode C. elegans that accumulate throughout its lifespan. During my postdoc at UCSF I hopes to identify a circRNA signature for specific oncogenes such as Myc then dissect the pathways necessary for circRNA-dependent oncogenesis.

    Collapse Research 
    Collapse Research Activities and Funding
    Identification of functional non-coding RNAs in Human Breast Cancer
    NIH F32CA236411Dec 3, 2018 - Dec 2, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Faculty Mentoring

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Global accumulation of circRNAs during aging in Caenorhabditis elegans. BMC Genomics. 2018 01 03; 19(1):8. Cortés-López M, Gruner MR, Cooper DA, Gruner HN, Voda AI, van der Linden AM, Miura P. PMID: 29298683; PMCID: PMC5753478.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    2. Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription Factors. PLoS Genet. 2016 08; 12(8):e1006237. Gruner M, Grubbs J, McDonagh A, Valdes D, Winbush A, van der Linden AM. PMID: 27487365; PMCID: PMC4972359.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    3. Long-term imaging of circadian locomotor rhythms of a freely crawling C. elegans population. J Neurosci Methods. 2015 Jul 15; 249:66-74. Winbush A, Gruner M, Hennig GW, van der Linden AM. PMID: 25911068; PMCID: PMC4821420.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    4. Plasticity of chemoreceptor gene expression: Sensory and circuit inputs modulate state-dependent chemoreceptors. Worm. 2015 Apr-Jun; 4(2):e1023497. Gruner M, van der Linden AM. PMID: 26430563; PMCID: PMC4588537.
      View in: PubMed   Mentions: 1  
    5. Feeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputs. PLoS Genet. 2014 Oct; 10(10):e1004707. Gruner M, Nelson D, Winbush A, Hintz R, Ryu L, Chung SH, Kim K, Gabel CV, van der Linden AM. PMID: 25357003; PMCID: PMC4214617.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    6. Metabolic labeling of Caenorhabditis elegans primary embryonic cells with azido-sugars as a tool for glycoprotein discovery. PLoS One. 2012; 7(11):e49020. Burnham-Marusich AR, Snodgrass CJ, Johnson AM, Kiyoshi CM, Buzby SE, Gruner MR, Berninsone PM. PMID: 23152843; PMCID: PMC3495777.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells