Matthew Hangauer, PhD

TitleAssistant Researcher
InstitutionUniversity of California San Francisco
DepartmentDiabetes Center
Address1450 3rd Street
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    UC BerkeleyPh.D.2009Chemistry
    Vanderbilt UniversityB.S., summa cum laude2003Chemistry
    Collapse Awards and Honors
    2016Best Talk, UCSF Cancer Center Conference
    2010  - 2013Susan G. Komen For the Cure Postdoctoral Fellowship
    2003  - 2006National Defense Science and Engineering Graduate Fellowship
    2001  - 2003Barry Goldwater Scholarship
    2001  - 2003McMinn Honor Scholarship (Top 2 Science Students), Vanderbilt
    1999  - 2003Dean's Select Honor Scholarship, Vanderbilt

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Hangauer M, Viswanathan VS, Ryan MJ, Bole D, Eaton JK, Matov A, Galeas J, Dhruv HD, Berens ME, Schreiber SL, McCormick F, McManus MT. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. Nature. 2017 11 09; 551(7679):247-250. PMID: 29088702.
      View in: PubMed
    2. Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance. Mol Cancer Res. 2016 08; 14(8):675-82. PMID: 27401613; PMCID: PMC4987219 [Available on 08/01/17].
    3. Tetsu O, Hangauer M, Phuchareon J, Eisele DW, McCormick F. Drug Resistance to EGFR Inhibitors in Lung Cancer. Chemotherapy. 2016; 61(5):223-35. PMID: 26910730; PMCID: PMC4844777 [Available on 02/25/17].
    4. Tetsu O, Phuchareon J, Eisele DW, Hangauer M, McCormick F. AKT inactivation causes persistent drug tolerance to EGFR inhibitors. Pharmacol Res. 2015 Dec; 102:132-7. PMID: 26453958.
      View in: PubMed
    5. Integrative analysis of 111 reference human epigenomes. Nature. 2015 Feb 19; 518(7539):317-30. PMID: 25693563; PMCID: PMC4530010.
    6. Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, Delaney A, Tam A, Kamoh B, Cho S, Griffith M, Chu A, Robertson G, Cheung D, Li I, Heravi-Moussavi A, Moksa M, Mingay M, Hussainkhel A, Davis B, Nagarajan RP, Hong C, Echipare L, O'Geen H, Hangauer M, Cheng JB, Neel D, Hu D, McManus MT, Moore R, Mungall A, Ma Y, Plettner P, Ziv E, Wang T, Farnham PJ, Jones SJ, Marra MA, Tlsty TD, Costello JF, Hirst M. Epigenetic and transcriptional determinants of the human breast. Nat Commun. 2015 Feb 18; 6:6351. PMID: 25690954; PMCID: PMC4346612.
    7. Hangauer M, Carpenter S, McManus MT. Discovering the complexity of the metazoan transcriptome. Genome Biol. 2014 Apr 29; 15(4):112. PMID: 25001157; PMCID: PMC4054782.
    8. Palaniappan KK, Hangauer M, Smith TJ, Smart BP, Pitcher AA, Cheng EH, Bertozzi CR, Boyce M. A chemical glycoproteomics platform reveals O-GlcNAcylation of mitochondrial voltage-dependent anion channel 2. Cell Rep. 2013 Oct 31; 5(2):546-52. PMID: 24120863; PMCID: PMC3869705.
    9. Hangauer M, Vaughn IW, McManus MT. Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet. 2013 Jun; 9(6):e1003569. PMID: 23818866; PMCID: PMC3688513.
    10. Shieh P, Hangauer M, Bertozzi CR. Fluorogenic azidofluoresceins for biological imaging. J Am Chem Soc. 2012 Oct 24; 134(42):17428-31. PMID: 23025473; PMCID: PMC3596100.
    11. Ku GM, Kim H, Vaughn IW, Hangauer M, Myung Oh C, German MS, McManus MT. Research resource: RNA-Seq reveals unique features of the pancreatic ß-cell transcriptome. Mol Endocrinol. 2012 Oct; 26(10):1783-92. PMID: 22915829; PMCID: PMC3458219.
    12. Boyce M, Carrico IS, Ganguli AS, Yu SH, Hangauer M, Hubbard SC, Kohler JJ, Bertozzi CR. Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway. Proc Natl Acad Sci U S A. 2011 Feb 22; 108(8):3141-6. PMID: 21300897; PMCID: PMC3044403.
    13. Beatty KE, Fisk JD, Smart BP, Lu YY, Szychowski J, Hangauer M, Baskin JM, Bertozzi CR, Tirrell DA. Live-cell imaging of cellular proteins by a strain-promoted azide-alkyne cycloaddition. Chembiochem. 2010 Oct 18; 11(15):2092-5. PMID: 20836119; PMCID: PMC3069858.
    14. Barb AW, Leavy TM, Robins LI, Guan Z, Six DA, Zhou P, Hangauer M, Bertozzi CR, Raetz CR. Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC. Biochemistry. 2009 Apr 14; 48(14):3068-77. PMID: 19256534; PMCID: PMC2709817.
    15. Hangauer M, Bertozzi CR. A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation. Angew Chem Int Ed Engl. 2008; 47(13):2394-7. PMID: 18306205; PMCID: PMC2446402.
    16. Kostiuk MA, Corvi MM, Keller BO, Plummer G, Prescher JA, Hangauer M, Bertozzi CR, Rajaiah G, Falck JR, Berthiaume LG. Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue. FASEB J. 2008 Mar; 22(3):721-32. PMID: 17971398; PMCID: PMC2860959.
    17. Chang PV, Prescher JA, Hangauer M, Bertozzi CR. Imaging cell surface glycans with bioorthogonal chemical reporters. J Am Chem Soc. 2007 Jul 11; 129(27):8400-1. PMID: 17579403; PMCID: PMC2535820.
    18. Laughlin ST, Agard NJ, Baskin JM, Carrico IS, Chang PV, Ganguli AS, Hangauer M, Lo A, Prescher JA, Bertozzi CR. Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics. Methods Enzymol. 2006; 415:230-50. PMID: 17116478.
      View in: PubMed
    19. Norris JL, Hangauer M, Porter NA, Caprioli RM. Nonacid cleavable detergents applied to MALDI mass spectrometry profiling of whole cells. J Mass Spectrom. 2005 Oct; 40(10):1319-26. PMID: 16220468.
      View in: PubMed
    20. Milkiewicz KL, Marsilje TH, Woodworth RP, Bifulco N, Hangauer M, Hangauer DG. The design, synthesis and activity of non-ATP competitive inhibitors of pp60(c-src) tyrosine kinase. Part 2: hydroxyindole derivatives. Bioorg Med Chem Lett. 2000 Mar 06; 10(5):483-6. PMID: 10743953.
      View in: PubMed