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Matthew O'Meara, PhD

TitlePostdoctoral Scholar
SchoolUCSF School of Pharmacy
DepartmentPharmaceutical Chemistry
Address1700 4th Street
San Francisco CA 94158
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    Collapse Research 
    Collapse Research Activities and Funding
    A metabolic code for cell signaling and polypharmacology.
    NIH/NIGMS F32GM114961Mar 1, 2016 - Feb 28, 2018
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Alford RF, Leaver-Fay A, Jeliazkov JR, O'Meara M, DiMaio FP, Park H, Shapovalov MV, Renfrew PD, Mulligan VK, Kappel K, Labonte JW, Pacella MS, Bonneau R, Bradley P, Dunbrack RL, Das R, Baker D, Kuhlman B, Kortemme T, Gray JJ. The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design. J Chem Theory Comput. 2017 Jun 13; 13(6):3031-3048. PMID: 28430426.
      View in: PubMed
    2. Barelier S, Sterling T, O'Meara M, Shoichet BK. The Recognition of Identical Ligands by Unrelated Proteins. ACS Chem Biol. 2015 Dec 18; 10(12):2772-84. PMID: 26421501; PMCID: PMC4684825 [Available on 12/18/16].
    3. Ó Conchúir S, Barlow KA, Pache RA, Ollikainen N, Kundert K, O'Meara M, Smith CA, Kortemme T. A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design. PLoS One. 2015; 10(9):e0130433. PMID: 26335248; PMCID: PMC4559433.
    4. O'Meara M, Leaver-Fay A, Tyka MD, Stein A, Houlihan K, DiMaio F, Bradley P, Kortemme T, Baker D, Snoeyink J, Kuhlman B. Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta. J Chem Theory Comput. 2015 Feb 10; 11(2):609-22. PMID: 25866491; PMCID: PMC4390092.
    5. O'Meara TR, Xu W, Selvig KM, O'Meara M, Mitchell AP, Alspaugh JA. The Cryptococcus neoformans Rim101 transcription factor directly regulates genes required for adaptation to the host. Mol Cell Biol. 2014 Feb; 34(4):673-84. PMID: 24324006; PMCID: PMC3911494.
    6. Harrison JS, Higgins CD, O'Meara M, Koellhoffer JF, Kuhlman BA, Lai JR. Role of electrostatic repulsion in controlling pH-dependent conformational changes of viral fusion proteins. Structure. 2013 Jul 02; 21(7):1085-96. PMID: 23823327; PMCID: PMC3701885.
    7. Leaver-Fay A, O'Meara M, Tyka M, Jacak R, Song Y, Kellogg EH, Thompson J, Davis IW, Pache RA, Lyskov S, Gray JJ, Kortemme T, Richardson JS, Havranek JJ, Snoeyink J, Baker D, Kuhlman B. Scientific benchmarks for guiding macromolecular energy function improvement. Methods Enzymol. 2013; 523:109-43. PMID: 23422428; PMCID: PMC3724755.
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