Mausam Kalita, PhD

TitleAssistant Researcher
InstitutionUniversity of California San Francisco
Address1450 Third St
San Francisco CA 94158
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    Collapse Awards and Honors
    Kansas State University2008Terry C. Johnson Basic Cancer Research Award
    Kansas State University 2010Fateley-Hammaker Collaboration in Research Award
    Gordon Conference 2014Invited Speaker, Late Breaking Topics
    JACS, Bioconjugate Chemistry, Molecular Imaging, Nanomedicine:Nanotechnology, Biology and Medicine2016Reviewer

    Collapse Overview 
    Collapse Overview
    My ambition is to develop novel optical and chemical tools to solve diagnostic and therapeutic problems by integrating organic and material chemistry, biochemistry and biology. My research in chemistry-nanoscience-glycobiology interface has produced several peer-reviewed publications and a patent involving a nanosensor which diagnoses life-threatening contaminant in pharmaceutical grade heparin, an anticoagulant used extensively during surgery. This probe will protect humans from severe immune response stimulated by this contaminant. I am currently developing several other biosensors, which can image biomarkers involved in pathophysiological conditions such as cancer, diabetes, arthritis and bacterial infection. At UCSF, my projects focus on the development of a) low nanomolar inhibitors of glycosyltransferase enzymes for glioblastoma therapy (PI- Joanna Phillips) and b) PET probes for selective imaging of active bacterial infection (PI- David Wilson). We are excited to introduce our first PET probe in humans for infection screening later in 2018.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chua JS, Tran VM, Kalita M, Quintero MV, Antelope O, Muruganandam G, Saijoh Y, Kuberan B. A glycan-based approach to therapeutic angiogenesis. PLoS One. 2017; 12(8):e0182301. PMID: 28763512.
      View in: PubMed
    2. Holman HA, Tran VM, Kalita M, Nguyen LN, Arungundram S, Kuberan B, Rabbitt RD. BODIPY-Conjugated Xyloside Primes Fluorescent Glycosaminoglycans in the Inner Ear of Opsanus tau. J Assoc Res Otolaryngol. 2016 Dec; 17(6):525-540. PMID: 27619213.
      View in: PubMed
    3. Kalita M, Quintero MV, Raman K, Tran VM, Kuberan B. Synthesis and biomedical applications of xylosides. Methods Mol Biol. 2015; 1229:517-28. PMID: 25325977.
      View in: PubMed
    4. Wang H, Udukala DN, Samarakoon TN, Basel MT, Kalita M, Abayaweera G, Manawadu H, Malalasekera A, Robinson C, Villanueva D, Maynez P, Bossmann L, Riedy E, Barriga J, Wang N, Li P, Higgins DA, Zhu G, Troyer DL, Bossmann SH. Nanoplatforms for highly sensitive fluorescence detection of cancer-related proteases. Photochem Photobiol Sci. 2014 Feb; 13(2):231-40. PMID: 24096539.
      View in: PubMed
    5. Kalita M, Balivada S, Swarup VP, Mencio C, Raman K, Desai UR, Troyer D, Kuberan B. A nanosensor for ultrasensitive detection of oversulfated chondroitin sulfate contaminant in heparin. J Am Chem Soc. 2014 Jan 15; 136(2):554-7. PMID: 24127748.
      View in: PubMed
    6. Perera AS, Subbaiyan NK, Kalita M, Wendel SO, Samarakoon TN, D'Souza F, Bossmann SH. A hybrid soft solar cell based on the mycobacterial porin MspA linked to a sensitizer-viologen Diad. J Am Chem Soc. 2013 May 08; 135(18):6842-5. PMID: 23611424.
      View in: PubMed
    7. Perera AS, Wang H, Basel MT, Pokhrel MR, Gamage PS, Kalita M, Wendel S, Sears B, Welideniya D, Liu Y, Turro C, Troyer DL, Bossmann SH. Channel blocking of MspA revisited. Langmuir. 2013 Jan 08; 29(1):308-15. PMID: 23214433.
      View in: PubMed
    8. Shrestha TB, Kalita M, Pokhrel MR, Liu Y, Troyer DL, Turro C, Bossmann SH, Dürr H. Maleimide-functionalized photochromic spirodihydroindolizines. J Org Chem. 2013 Mar 01; 78(5):1903-9. PMID: 23095100.
      View in: PubMed
    9. Shrestha TB, Seo GM, Basel MT, Kalita M, Wang H, Villanueva D, Pyle M, Balivada S, Rachakatla RS, Shinogle H, Thapa PS, Moore D, Troyer DL, Bossmann SH. Stem cell-based photodynamic therapy. Photochem Photobiol Sci. 2012 Jul; 11(7):1251-8. PMID: 22565929.
      View in: PubMed
    10. Kalita M, Cingarapu S, Roy S, Park SC, Higgins D, Jankowiak R, Chikan V, Klabunde KJ, Bossmann SH. Direct synthesis of aqueous quantum dots through 4,4'-bipyridine-based twin ligand strategy. Inorg Chem. 2012 Apr 16; 51(8):4521-6. PMID: 22443511.
      View in: PubMed
    11. Dani RK, Kang M, Kalita M, Smith PE, Bossmann SH, Chikan V. MspA Porin-Gold Nanoparticle Assemblies: Enhanced Binding through a Controlled Cysteine Mutation. Nano Lett. 2008 Apr; 8(4):1229-36. PMID: 18318505.
      View in: PubMed
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