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a1ß1 integrin-mediated adhesion inhibits macrophage exit from a peripheral inflammatory lesion. J Immunol. 2013 Apr 15; 190(8):4305-14.
Becker HM, Rullo J, Chen M, Ghazarian M, Bak S, Xiao H, Hay JB, Cybulsky MI. PMID: 23509351.
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18 Fields:
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AnimalsCells
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D-series resolvin attenuates vascular smooth muscle cell activation and neointimal hyperplasia following vascular injury. FASEB J. 2013 Jun; 27(6):2220-32.
Miyahara T, Runge S, Chatterjee A, Chen M, Mottola G, Fitzgerald JM, Serhan CN, Conte MS. PMID: 23407709.
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48 Fields:
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HumansAnimalsCells
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Talin-1 and kindlin-3 regulate alpha4beta1 integrin-mediated adhesion stabilization, but not G protein-coupled receptor-induced affinity upregulation. J Immunol. 2011 Oct 15; 187(8):4360-8.
Hyduk SJ, Rullo J, Cano AP, Xiao H, Chen M, Moser M, Cybulsky MI. PMID: 21911599.
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PubMed Mentions:
20 Fields:
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HumansAnimalsCells
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Increased oxidative stress in atherosclerosis-predisposed regions of the mouse aorta. Life Sci. 2010 Jul 17; 87(3-4):100-10.
Haidari M, Ali M, Gangehei L, Chen M, Zhang W, Cybulsky MI. PMID: 20553954.
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PubMed Mentions:
10 Fields:
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Animals
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Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis. Circ Res. 2010 Feb 05; 106(2):383-90.
Paulson KE, Zhu SN, Chen M, Nurmohamed S, Jongstra-Bilen J, Cybulsky MI. PMID: 19893012.
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108 Fields:
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AnimalsCells
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Discoidin domain receptor 1 on bone marrow-derived cells promotes macrophage accumulation during atherogenesis. Circ Res. 2009 Nov 20; 105(11):1141-8.
Franco C, Britto K, Wong E, Hou G, Zhu SN, Chen M, Cybulsky MI, Bendeck MP. PMID: 19834008.
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23 Fields:
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AnimalsCells
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GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions. J Exp Med. 2009 Sep 28; 206(10):2141-9.
Zhu SN, Chen M, Jongstra-Bilen J, Cybulsky MI. PMID: 19752185.
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PubMed Mentions:
66 Fields:
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AnimalsCells
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Relative reduction of endothelial nitric-oxide synthase expression and transcription in atherosclerosis-prone regions of the mouse aorta and in an in vitro model of disturbed flow. Am J Pathol. 2007 Nov; 171(5):1691-704.
Won D, Zhu SN, Chen M, Teichert AM, Fish JE, Matouk CC, Bonert M, Ojha M, Marsden PA, Cybulsky MI. PMID: 17982133.
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53 Fields:
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AnimalsCells
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Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 01; 109(1):176-84.
Hyduk SJ, Chan JR, Duffy ST, Chen M, Peterson MD, Waddell TK, Digby GC, Szaszi K, Kapus A, Cybulsky MI. PMID: 16960156.
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PubMed Mentions:
41 Fields:
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HumansCells
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Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis. J Exp Med. 2006 Sep 04; 203(9):2073-83.
Jongstra-Bilen J, Haidari M, Zhu SN, Chen M, Guha D, Cybulsky MI. PMID: 16894012.
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PubMed Mentions:
125 Fields:
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AnimalsCells
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Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science. 2004 Nov 26; 306(5701):1558-61.
Ricci R, Sumara G, Sumara I, Rozenberg I, Kurrer M, Akhmedov A, Hersberger M, Eriksson U, Eberli FR, Becher B, Borén J, Chen M, Cybulsky MI, Moore KJ, Freeman MW, Wagner EF, Matter CM, Lüscher TF. PMID: 15567863.
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PubMed Mentions:
100 Fields:
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AnimalsCells
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Paxillin selectively associates with constitutive and chemoattractant-induced high-affinity alpha4beta1 integrins: implications for integrin signaling. Blood. 2004 Nov 01; 104(9):2818-24.
Hyduk SJ, Oh J, Xiao H, Chen M, Cybulsky MI. PMID: 15242880.
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PubMed Mentions:
13 Fields:
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HumansAnimalsCells
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Tracking of leukocyte recruitment into tissues of mice by in situ labeling of blood cells with the fluorescent dye CFDA SE. J Immunol Methods. 2004 Mar; 286(1-2):69-78.
Becker HM, Chen M, Hay JB, Cybulsky MI. PMID: 15087222.
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PubMed Mentions:
19 Fields:
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AnimalsCells
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A major role for VCAM-1, but not ICAM-1, in early atherosclerosis. J Clin Invest. 2001 May; 107(10):1255-62.
Cybulsky MI, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, Davis V, Gutierrez-Ramos JC, Connelly PW, Milstone DS. PMID: 11375415.
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330 Fields:
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Animals
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The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):9052-7.
Hajra L, Evans AI, Chen M, Hyduk SJ, Collins T, Cybulsky MI. PMID: 10922059.
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PubMed Mentions:
171 Fields:
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AnimalsCells
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The thrombin receptor second cytoplasmic loop confers coupling to Gq-like G proteins in chimeric receptors. Additional evidence for a common transmembrane signaling and G protein coupling mechanism in G protein-coupled receptors. J Biol Chem. 1997 Mar 14; 272(11):6898-902.
Verrall S, Ishii M, Chen M, Wang L, Tram T, Coughlin SR. PMID: 9054376.
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PubMed Mentions:
14 Fields:
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HumansAnimalsCells
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Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function. J Biol Chem. 1996 Jun 14; 271(24):13943-7.
Lerner DJ, Chen M, Tram T, Coughlin SR. PMID: 8662993.
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PubMed Mentions:
28 Fields:
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AnimalsCells
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Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling. J Biol Chem. 1996 Jan 12; 271(2):702-6.
Nanevicz T, Wang L, Chen M, Ishii M, Coughlin SR. PMID: 8557676.
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PubMed Mentions:
17 Fields:
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HumansAnimalsCells
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Tethered ligand library for discovery of peptide agonists. J Biol Chem. 1995 Oct 06; 270(40):23398-401.
Chen J, Bernstein HS, Chen M, Wang L, Ishii M, Turck CW, Coughlin SR. PMID: 7559498.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Mechanisms of thrombin receptor agonist specificity. Chimeric receptors and complementary mutations identify an agonist recognition site. J Biol Chem. 1995 Sep 15; 270(37):21619-25.
Nanevicz T, Ishii M, Wang L, Chen M, Chen J, Turck CW, Cohen FE, Coughlin SR. PMID: 7665575.
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PubMed Mentions:
20 Fields:
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HumansAnimalsCells