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Michael Thompson, PhD

Title(s)Postdoctoral Scholar, Bioengineering
SchoolSchool of Pharmacy
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    Collapse Research 
    Collapse Research Activities and Funding
    Biophysical rescue of Coagulation Factor IXa conformational ensembles from hemophilia B disease mutations
    NIH/NHLBI F32HL129989Sep 1, 2015 - Aug 31, 2018
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Thompson MC, Barad BA, Wolff AM, Sun Cho H, Schotte F, Schwarz DMC, Anfinrud P, Fraser JS. Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme. Nat Chem. 2019 11; 11(11):1058-1066. PMID: 31527847.
      View in: PubMed
    2. Thompson MC, Cascio D, Yeates TO. Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol. 2018 05 01; 74(Pt 5):411-421. PMID: 29717712.
      View in: PubMed
    3. Acker TM, Gable JE, Bohn MF, Jaishankar P, Thompson MC, Fraser JS, Renslo AR, Craik CS. Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases. J Am Chem Soc. 2017 08 30; 139(34):11650-11653. PMID: 28759216.
      View in: PubMed
    4. Biel JT, Thompson MC, Cunningham CN, Corn JE, Fraser JS. Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin. Structure. 2017 05 02; 25(5):739-749.e3. PMID: 28416112.
      View in: PubMed
    5. Thompson MC. Identifying and Overcoming Crystal Pathologies: Disorder and Twinning. Methods Mol Biol. 2017; 1607:185-217. PMID: 28573574.
      View in: PubMed
    6. Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, Brunger AT, Soltis SM, Lemke H, Gonzalez A, Sauter NK, Cohen AE, van den Bedem H, Thorne RE, Fraser JS. Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography. Elife. 2015 Sep 30; 4. PMID: 26422513.
      View in: PubMed