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Michael Hope, MD

Title(s)Professor, Radiology
SchoolSchool of Medicine
Address4150 Clement St
San Francisco CA 94121
Phone415-221-4810 ext. 22650
ORCID ORCID Icon0000-0001-9832-5732 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.2004School of Medicine
    University of California, San FranciscoResidency 2009Radiology
    University of California, San FranciscoFellowship2010Cardiopulmonary Imaging
    Collapse Awards and Honors
    Society of Computeed Body Tomography and Magnetic Resonance (SCBT/MR)2004Lauterbur Award Young Investigator Research Abstract Awards
    North American Society for Cardiovascular Imaging (NASCI)20081st Prize Bayer Poster Competition
    North American Society for Cardiovascular Imaging (NASCI)20091st Prize Young Investigator Award
    Radiological Society of North America (RSNA)2008Resident Research Grant
    Radiological Society of North America (RSNA)2012Research Scholar Grant
    Magnetic Resonance in Medicine2013Distinguished Reviewer
    Haile T. Debas Academy of Medical Educators, UCSF2015Excellence in Teaching Award
    NIH/NHLBI2015R01 Grant
    University of Nebraska Medical Center2017Charles A. Dobry Visiting Professor
    International Society for Magnetic Resonance in Medicine (ISMRM)2017Outstanding Teacher Award
    San Francisco VA Health Care System2019Certificate of Excellence
    VA Office of Research and Development (ORD) Clinical Science Research and Development (CSR&D)2020VA Merit Award

    Collapse Overview 
    Collapse Overview
    Michael D. Hope, MD, is a Professor in Residence and Vice-Chair in the Department of Radiology and Biomedical Imaging at UCSF. He is Chief of Radiology at the San Francisco VA Health Care System (SFVAHCS). Dr. Hope obtained his medical degree from Stanford. He did a Medicine internship at California Pacific Medical Center, and then completed both his Diagnostic Radiology residency and fellowship in Cardiopulmonary Imaging at UCSF.

    My principal research interest is studying the drivers of cardiovascular disease. My focus has been the application of advanced imaging techniques to better understand progressive aortic disease. These techniques include hemodynamic imaging with 4D Flow MRI, imaging of inflammation with a hybrid PET/MRI approach, and vessel lumen and wall imaging with novel MRI contrast agents. The overall goal is to target challenging and incompletely understood cardiovascular issues as detailed below, and use innovative imaging-derived analyses to better inform their clinical management.

    Since assuming the role of Chief of Radiology at SFVAHCS in 2018, I have worked to organize, diversify and reinvigorate imaging research at the VA. We have established a new research leadership group called the VA Advanced Imaging Research Center (VAARC), which is intended to mirror the research structure of the UCSF Radiology Department and to clearly define responsibilities in a democratic leadership framework. The overarching goal is to promote teamwork as we strengthen and broaden our unique VA research program. We established a Steering Committee for VAARC that meets monthly and is composed of Directors for the 5 research domains (i.e., Neuro, CV, Body, AI and Informatics, Advanced Imaging), Key Investigators (M. Weiner) and the Chief of Radiology, who chairs the committee and facilitates discussion.

    With our colleagues in Orthopedic Surgery at SFVAHCS, we established a VISN 21 Anatomic 3D Visualization/Printing Service in 2020 called Translational Radiology and Surgical Technologies, or TRST, that will provide 3D advanced visualization and printed to models of radiology exams to improve surgical planning for Veterans and concurrently improve resource utilization of VHA OR suites. This center will be based out of San Francisco. To develop this program, we have been granted FTE for two 3D technologists and a Biomedical Engineer, in addition to generous start up funds for hardware and software resources to enable routine 3D printing and/or visualization of cross-sectional studies, including capabilities for virtual and augmented reality.

    Along with my colleague Travis Henry, I have taken on the issue of the judicious use of imaging during the COVID-19 pandemic. We have published in leading journals (Lancet, Annals of Internal Medicine) about the importance of careful and critical review of literature as we collectively better understand the role that CT may play in the management of COVID-19.

    *Abnormal systolic blood flow with valve-related aortic disease.* My early cardiovascular research investigated hemodynamic alterations seen with aortic valve disease, a common clinical issue with relevance for up to 4% of people. Using 4D Flow MR imaging, I was the first to describe the helical systolic blood flow in the ascending thoracic aorta of patients with bicuspid aortic valves (BAV), and relate it to different aortic valve leaflet fusion patterns and the valve-related aortic disease seen in this population.

    *Quantifying eccentric blood flow.* I hypothesized that the abnormal valve-related aortic flow we observed with BAV was directly related to asymmetrically elevated aortic wall shear stress, and as a consequence, that eccentric flow is associated with increased aortic growth rates. To better evaluate this, we explored a range of quantitative approaches to describe eccentric systolic blood flow and correlated them with growth.

    *Advanced cardiovascular imaging with 4D Flow.* Our group at UCSF has pioneered the use of 4D Flow imaging for neurovascular and aortic evaluation. We have focused on practical, noninvasive clinical applications for challenging cardiovascular issues that may otherwise need invasive tests. We have expanded our investigation of hemodynamics with sequences that allow quantification of flow turbulence.

    *Advanced aortic imaging.* I believe that a combined hemodynamic and inflammatory assessment using functional aortic imaging techniques will have the greatest impact in the evaluation of abdominal aortic aneurysms (AAA). We have explored new functional techniques including vessel wall strain analysis, inflammatory imaging, and combined PET/MRI. We seek to meaningfully advance the assessment of risk in patients who do not meet current intervention thresholds and improve outcomes by refining surveillance imaging regimens and decisions regarding early intervention for AAAs.

    *Improved risk stratification of abdominal aortic aneurysm (AAA) disease.* Currently maximum aortic diameter is the principal metric used to manage AAA disease clinically, but this approach misses much of the complexity of the disease process, including intraluminal thrombus (ILT) and wall stress. We have focused on better defining the relationship between a range of anatomic and hemodynamic parameters and disease progression.

    Collapse Research 
    Collapse Research Activities and Funding
    Advanced MRI Evaluation of Abdominal Aortic Aneurysms
    VA I01CX002071Oct 1, 2020 - Sep 30, 2024
    Role: Principal Investigator
    Advanced MRI Evaluation of Abdominal Aortic Aneurysms
    VA ORD/CSR&D VA Merit Award (CX-002071-01A1)Apr 1, 2020 - Mar 31, 2024
    Role: Co-Principal Investigator
    Hemodynamic and inflammatory imaging in evaluation of abdominal aortic aneurysms
    NIH/NHLBI R01HL123759Jan 1, 2015 - Dec 31, 2018
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. When to rule out COVID-19: How many negative RT-PCR tests are needed? Respir Med Case Rep. 2020; 31:101192. Isikbay M, Henry TS, Frank JA, Hope MD. PMID: 32837902.
      View in: PubMed   Mentions:
    2. Reply to Letters Addressing "Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date". AJR Am J Roentgenol. 2020 Jul 13; W1-W2. Raptis CA, Hammer MM, Henry TS, Hope MD, Bhalla S. PMID: 32755176.
      View in: PubMed   Mentions:    Fields:    
    3. What Do We Really Know About Pulmonary Thrombosis in COVID-19 Infection? J Thorac Imaging. 2020 Jun 29. Raptis CA, Hammer MM, Henry TS, Hope MD, Schiebler ML, van Beek EJR. PMID: 32618808.
      View in: PubMed   Mentions:    Fields:    
    4. Chest CT Imaging Signature of Coronavirus Disease 2019 Infection: In Pursuit of the Scientific Evidence. Chest. 2020 Jun 25. Adams HJA, Kwee TC, Yakar D, Hope MD, Kwee RM. PMID: 32592709.
      View in: PubMed   Mentions: 2     Fields:    
    5. The Limited Sensitivity of Chest Computed Tomography Relative to Reverse Transcription Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Systematic Review on COVID-19 Diagnostics. Invest Radiol. 2020 Jun 16. Waller JV, Allen IE, Lin KK, Diaz MJ, Henry TS, Hope MD. PMID: 32554983.
      View in: PubMed   Mentions: 3     Fields:    
    6. Systematic Review and Meta-Analysis on the Value of Chest CT in the Diagnosis of Coronavirus Disease (COVID-19): Sol Scientiae, Illustra Nos. AJR Am J Roentgenol. 2020 Jun 01; 1-9. Adams HJA, Kwee TC, Yakar D, Hope MD, Kwee RM. PMID: 32478562.
      View in: PubMed   Mentions: 1     Fields:    
    7. Challenges in the interpretation and application of typical imaging features of COVID-19. Lancet Respir Med. 2020 06; 8(6):534-536. Hammer MM, Raptis CA, Henry TS, Shah A, Bhalla S, Hope MD. PMID: 32437649.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    8. Diagnostic Tools for Coronavirus Disease (COVID-19): Comparing CT and RT-PCR Viral Nucleic Acid Testing. AJR Am J Roentgenol. 2020 10; 215(4):834-838. Waller JV, Kaur P, Tucker A, Lin KK, Diaz MJ, Henry TS, Hope M. PMID: 32412790.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    9. How to Measure the Aorta Using MRI: A Practical Guide. J Magn Reson Imaging. 2020 Oct; 52(4):971-977. van Hout MJ, Scholte AJ, Juffermans JF, Westenberg JJ, Zhong L, Zhou X, Schalla SM, Hope MD, Bremerich J, Kramer CM, Dewey M, Ordovas KG, Bluemke DA, Lamb HJ. PMID: 32374422.
      View in: PubMed   Mentions:    Fields:    
    10. Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date. AJR Am J Roentgenol. 2020 10; 215(4):839-842. Raptis CA, Hammer MM, Short RG, Shah A, Bhalla S, Bierhals AJ, Filev PD, Hope MD, Jeudy J, Kligerman SJ, Henry TS. PMID: 32298149.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCellsPHPublic Health
    11. Chest Computed Tomography for Detection of Coronavirus Disease 2019 (COVID-19): Don't Rush the Science. Ann Intern Med. 2020 07 21; 173(2):147-148. Hope MD, Raptis CA, Henry TS. PMID: 32267912.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    12. A role for CT in COVID-19? What data really tell us so far. Lancet. 2020 04 11; 395(10231):1189-1190. Hope MD, Raptis CA, Shah A, Hammer MM, Henry TS. PMID: 32224299.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsPHPublic Health
    13. Impact of hybrid supervision approaches on the performance of artificial intelligence for the classification of chest radiographs. Comput Biol Med. 2020 May; 120:103699. Ellis R, Ellestad E, Elicker B, Hope MD, Tosun D. PMID: 32217281.
      View in: PubMed   Mentions:    Fields:    
    14. Wall Stress Distribution in Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysms. Ann Thorac Surg. 2020 09; 110(3):807-814. Gomez A, Wang Z, Xuan Y, Wisneski AD, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE. PMID: 32006475.
      View in: PubMed   Mentions:    Fields:    
    15. Growth of common iliac artery aneurysms coexisting with abdominal aortic aneurysms: associated factors and potential role of intraluminal thrombus. Quant Imaging Med Surg. 2020 Mar; 10(3):703-712. Wang Y, Zhu C, Leach J, Gasper W, Saloner D, Hope M. PMID: 32269930.
      View in: PubMed   Mentions:
    16. Wall stress analyses in patients with =5 cm versus <5 cm ascending thoracic aortic aneurysm. J Thorac Cardiovasc Surg. 2020 Feb 19. Wang Z, Flores N, Lum M, Wisneski AD, Xuan Y, Inman J, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE. PMID: 32178922.
      View in: PubMed   Mentions:    Fields:    
    17. Intraluminal Thrombus Predicts Rapid Growth of Abdominal Aortic Aneurysms. Radiology. 2020 03; 294(3):707-713. Zhu C, Leach JR, Wang Y, Gasper W, Saloner D, Hope MD. PMID: 31990263.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Approach to Abnormal Chest Computed Tomography Contrast Enhancement in the Hospitalized Patient. Radiol Clin North Am. 2020 Jan; 58(1):93-103. Kallianos KG, Hope MD, Henry TS. PMID: 31731905.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging. Nat Rev Cardiol. 2020 05; 17(5):298-312. Garg P, Swift AJ, Zhong L, Carlhäll CJ, Ebbers T, Westenberg J, Hope MD, Bucciarelli-Ducci C, Bax JJ, Myerson SG. PMID: 31819230.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Association of Receipt of Positron Emission Tomography-Computed Tomography With Non-Small Cell Lung Cancer Mortality in the Veterans Affairs Health Care System. JAMA Netw Open. 2019 11 01; 2(11):e1915828. Vella M, Meyer CS, Zhang N, Cohen BE, Whooley MA, Wang S, Hope MD. PMID: 31747036.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Surveillance of abdominal aortic aneurysm using accelerated 3D non-contrast black-blood cardiovascular magnetic resonance with compressed sensing (CS-DANTE-SPACE). J Cardiovasc Magn Reson. 2019 10 28; 21(1):66. Zhu C, Cao L, Wen Z, Ahn S, Raithel E, Forman C, Hope M, Saloner D. PMID: 31660983.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Multicenter Safety and Practice for Off-Label Diagnostic Use of Ferumoxytol in MRI. Radiology. 2019 12; 293(3):554-564. Nguyen KL, Yoshida T, Kathuria-Prakash N, Zaki IH, Varallyay CG, Semple SI, Saouaf R, Rigsby CK, Stoumpos S, Whitehead KK, Griffin LM, Saloner D, Hope MD, Prince MR, Fogel MA, Schiebler ML, Roditi GH, Radjenovic A, Newby DE, Neuwelt EA, Bashir MR, Hu P, Finn JP. PMID: 31638489.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. A Radiologist's Excursion in Four-dimensional Flow and the Bicuspid Aortic Valve: Vorticity, Helicity, Wall Shear Stress, and All That. Radiology. 2019 12; 293(3):551-553. Mitsouras D, Hope MD. PMID: 31596182.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. On the relative impact of intraluminal thrombus heterogeneity on abdominal aortic aneurysm mechanics. J Biomech Eng. 2019 Jun 29. Leach J, Kao E, Zhu C, Saloner D, Hope MD. PMID: 31253989.
      View in: PubMed   Mentions:    Fields:    
    25. Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI. J Magn Reson Imaging. 2019 09; 50(3):994-1001. Zhu C, Leach JR, Tian B, Cao L, Wen Z, Wang Y, Liu X, Liu Q, Lu J, Saloner D, Hope MD. PMID: 30694008.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    26. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary. J Thorac Cardiovasc Surg. 2018 08; 156(2):473-480. Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. PMID: 30011756.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version. J Thorac Cardiovasc Surg. 2018 08; 156(2):e41-e74. Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. PMID: 30011777.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. Retrograde flow in the false lumen: Marker of a false lumen under stress? J Thorac Cardiovasc Surg. 2019 02; 157(2):488-491. Burris NS, Patel HJ, Hope MD. PMID: 30126660.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Tailoring Radiology Resident Education Using Aggregated Missed-Cases Data. J Am Coll Radiol. 2018 Jul; 15(7):1013-1015. Merritt BA, Henry TS, Cha S, Ordovas KG, Kallianos KG, Elicker BM, Hope MD, Naeger DM. PMID: 29759529.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    30. Ferumoxtyol-enhanced MR Angiography for Transcatheter Aortic Valve Replacement Planning in Patients with Renal Failure. Radiology. 2018 04; 287(1):362-363. Zhu C, Kallianos K, Henry T, Hope MD. PMID: 29558308.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Letter by Zhu et al Regarding Article, "Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair". Circulation. 2018 03 20; 137(12):1293-1294. Zhu C, Saloner D, Hope MD. PMID: 29555713.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Wall stress on ascending thoracic aortic aneurysms with bicuspid compared with tricuspid aortic valve. J Thorac Cardiovasc Surg. 2018 08; 156(2):492-500. Xuan Y, Wang Z, Liu R, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng E. PMID: 29656820.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Feature Tracking Cardiac MRI Reveals Abnormalities in Ventricular Function in Patients With Bicuspid Aortic Valve and Preserved Ejection Fraction. Tomography. 2018 Mar; 4(1):26-32. Burris NS, Lima APS, Hope MD, Ordovas KG. PMID: 30042984.
      View in: PubMed   Mentions: 3     Fields:    
    34. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2018 Mar; 34(3):475-483. Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD. PMID: 28905233.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. 4D flow image quality with blood pool contrast: a comparison of gadofosveset trisodium and ferumoxytol. Int J Cardiovasc Imaging. 2018 Feb; 34(2):273-279. Mukai K, Burris NS, Mahadevan VS, Foster ED, Ordovas KG, Hope MD. PMID: 28884401.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Evolving treatment options for valve and aortic disease with bicuspid aortic valve. Ann Transl Med. 2017 Aug; 5(16):333. Burris NS, Hope MD. PMID: 28861430.
      View in: PubMed   Mentions:
    37. Segmentation of lumen and outer wall of abdominal aortic aneurysms from 3D black-blood MRI with a registration based geodesic active contour model. Med Image Anal. 2017 Aug; 40:1-10. Wang Y, Seguro F, Kao E, Zhang Y, Faraji F, Zhu C, Haraldsson H, Hope M, Saloner D, Liu J. PMID: 28549310.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. Pediatric chest CT at chest radiograph doses: when is the ultralow-dose chest CT clinically appropriate? Emerg Radiol. 2017 Aug; 24(4):369-376. Villanueva-Meyer JE, Naeger DM, Courtier JL, Hope MD, Lambert JW, MacKenzie JD, Phelps AS. PMID: 28289906.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Ferumoxytol MRA for transcatheter aortic valve replacement planning with renal insufficiency. Int J Cardiol. 2017 Mar 15; 231:255-257. Kallianos K, Henry TS, Yeghiazarians Y, Zimmet J, Shunk KA, Tseng EE, Mahadevan V, Hope MD. PMID: 28100426.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    40. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography. Eur Radiol. 2017 May; 27(5):1787-1794. Zhu C, Tian B, Leach JR, Liu Q, Lu J, Chen L, Saloner D, Hope MD. PMID: 27553926.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    41. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model. J Heart Valve Dis. 2016 07; 25(4):424-429. Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE. PMID: 28009944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Dilatation of the ascending aorta is associated with presence of aortic regurgitation in patients after repair of tetralogy of Fallot. Int J Cardiovasc Imaging. 2016 Aug; 32(8):1265-72. Ordovas KG, Keedy A, Naeger DM, Kallianos K, Foster E, Liu J, Saloner D, Hope MD. PMID: 27240599.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Ascending Aortic Stiffness with Bicuspid Aortic Valve is Variable and Not Predicted by Conventional Parameters in Young Patients. J Heart Valve Dis. 2016 05; 25(3):270-280. Burris NS, Dyverfeldt P, Hope MD. PMID: 27989036.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    44. Safety and technique of ferumoxytol administration for MRI. Magn Reson Med. 2016 May; 75(5):2107-11. Vasanawala SS, Nguyen KL, Hope MD, Bridges MD, Hope TA, Reeder SB, Bashir MR. PMID: 26890830.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    45. Intraprocedural Safety and Technical Success of the MVP Micro Vascular Plug for Embolization of Pulmonary Arteriovenous Malformations. J Vasc Interv Radiol. 2015 Nov; 26(11):1735-9. Conrad MB, Ishaque BM, Surman AM, Kerlan RK, Hope MD, Dickey MA, Hetts SW, Wilson MW. PMID: 26505940.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    46. Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysm: Patient-Specific Finite Element Analysis. J Heart Valve Dis. 2015 Nov; 24(6):714-721. Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. PMID: 27997777.
      View in: PubMed   Mentions:    Fields:    
    47. Isotropic 3D black blood MRI of abdominal aortic aneurysm wall and intraluminal thrombus. Magn Reson Imaging. 2016 Jan; 34(1):18-25. Zhu C, Haraldsson H, Faraji F, Owens C, Gasper W, Ahn S, Liu J, Laub G, Hope MD, Saloner D. PMID: 26471514.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Assessment of Left Ventricular Enlargement at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):794-6. Kathiria NN, Devcic Z, Chen JS, Naeger DM, Hope MD, Higgins CB, Ordovas KG. PMID: 26295194.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. 4D flow cardiovascular magnetic resonance consensus statement. J Cardiovasc Magn Reson. 2015 Aug 10; 17:72. Dyverfeldt P, Bissell M, Barker AJ, Bolger AF, Carlhäll CJ, Ebbers T, Francios CJ, Frydrychowicz A, Geiger J, Giese D, Hope MD, Kilner PJ, Kozerke S, Myerson S, Neubauer S, Wieben O, Markl M. PMID: 26257141.
      View in: PubMed   Mentions: 100     Fields:    Translation:Humans
    50. Ascending thoracic aortic aneurysm wall stress analysis using patient-specific finite element modeling of in vivo magnetic resonance imaging. Interact Cardiovasc Thorac Surg. 2015 Oct; 21(4):471-80. Krishnan K, Ge L, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Tseng EE. PMID: 26180089.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System. Radiology. 2016 Jan; 278(1):239-46. Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA. PMID: 26133050.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    52. Vascular Imaging With Ferumoxytol as a Contrast Agent. AJR Am J Roentgenol. 2015 Sep; 205(3):W366-73. Hope MD, Hope TA, Zhu C, Faraji F, Haraldsson H, Ordovas KG, Saloner D. PMID: 26102308.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    53. Vascular inflammation in a growing iliac artery aneurysm. Clin Nucl Med. 2015 Jun; 40(6):e323-4. Hope MD, Gasper WJ, Rapp J, Owens CD, Haraldsson H, Saloner D. PMID: 25674872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. Left atrial transverse diameter on computed tomography angiography can accurately diagnose left atrial enlargement in patients with atrial fibrillation. J Thorac Imaging. 2015 May; 30(3):214-7. Sohrabi S, Hope M, Saloner D, Keedy A, Naeger D, Lorca MC, Ordovas KG. PMID: 25629578.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Bicuspid valve-related aortic disease: flow assessment with conventional phase-contrast MRI. Acad Radiol. 2015 Jun; 22(6):690-6. Burris NS, Hope MD. PMID: 25769698.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    56. Extended 3D approach for quantification of abnormal ascending aortic flow. Magn Reson Imaging. 2015 Jun; 33(5):695-700. Sigovan M, Dyverfeldt P, Wrenn J, Tseng EE, Saloner D, Hope MD. PMID: 25721998.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    57. Four-dimensional magnetic resonance imaging-derived ascending aortic flow eccentricity and flow compression are linked to aneurysm morphology†. Interact Cardiovasc Thorac Surg. 2015 May; 20(5):582-7; discussion 587-8. Kari FA, Kocher N, Beyersdorf F, Tscheuschler A, Meffert P, Rylski B, Siepe M, Russe MF, Hope MD. PMID: 25636325.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    58. Prevalence and significance of incidentally noted dilation of the ascending aorta on routine chest computed tomography in older patients. J Comput Assist Tomogr. 2015 Jan-Feb; 39(1):109-11. Benedetti N, Hope MD. PMID: 25319605.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    59. Letter by Hope et al regarding article, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy". Circulation. 2014 Nov 04; 130(19):e170. Hope MD, Sigovan M, Dyverfeldt P. PMID: 25366842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Patient-specific finite element analysis of ascending thoracic aortic aneurysm. J Heart Valve Dis. 2014 Nov; 23(6):765-72. Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. PMID: 25790625.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    61. 4D flow MRI applications for aortic disease. Magn Reson Imaging Clin N Am. 2015 Feb; 23(1):15-23. Burris NS, Hope MD. PMID: 25476670.
      View in: PubMed   Mentions: 6     Fields:    
    62. Systolic flow displacement correlates with future ascending aortic growth in patients with bicuspid aortic valves undergoing magnetic resonance surveillance. Invest Radiol. 2014 Oct; 49(10):635-9. Burris NS, Sigovan M, Knauer HA, Tseng EE, Saloner D, Hope MD. PMID: 24784460.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    63. CT-reconstructed three-dimensional printed models of the right subclavian artery and aorta define age-related changes and facilitate benchtop catheter testing. J Invasive Cardiol. 2014 Oct; 26(10):E141-4. Velez E, Boyer N, Acevedo-Bolton G, Hope MD, Boyle A. PMID: 25274871.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    64. Diastolic function assessed by cardiac MRI using longitudinal left ventricular fractional shortening. Clin Imaging. 2014 Sep-Oct; 38(5):666-8. Dusch MN, Thadani SR, Dhillon GS, Hope MD. PMID: 25034401.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    65. Comprehensive evaluation of culture-negative endocarditis with use of cardiac and 4-dimensional-flow magnetic resonance imaging. Tex Heart Inst J. 2014 Jun; 41(3):351-2. Thadani SR, Dyverfeldt P, Gin A, Chitsaz S, Rao RK, Hope MD. PMID: 24955064.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    66. Highly accelerated aortic 4D flow MR imaging with variable-density random undersampling. Magn Reson Imaging. 2014 Oct; 32(8):1012-20. Liu J, Dyverfeldt P, Acevedo-Bolton G, Hope M, Saloner D. PMID: 24846341.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    67. Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2014 Jan 09; 16:6. Haraldsson H, Hope M, Acevedo-Bolton G, Tseng E, Zhong X, Epstein FH, Ge L, Saloner D. PMID: 24400865.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    68. Functional and molecular imaging techniques in aortic aneurysm disease. Curr Opin Cardiol. 2013 Nov; 28(6):609-18. Hope MD, Hope TA. PMID: 24030165.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    69. MRI hemodynamic markers of progressive bicuspid aortic valve-related aortic disease. J Magn Reson Imaging. 2014 Jul; 40(1):140-5. Hope MD, Sigovan M, Wrenn SJ, Saloner D, Dyverfeldt P. PMID: 24788592.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    70. Cardiovascular MR imaging after surgical correction of tetralogy of Fallot: approach based on understanding of surgical procedures. Radiographics. 2013 Jul-Aug; 33(4):1037-52. Ordovas KG, Muzzarelli S, Hope MD, Naeger DM, Karl T, Reddy GP, Marchiori E, Higgins CB. PMID: 23842971.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    71. Cardiothoracic magnetic resonance flow imaging. J Thorac Imaging. 2013 Jul; 28(4):217-30. Hope MD, Sedlic T, Dyverfeldt P. PMID: 23708687.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    72. Biomechanical properties of human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2013 Jul; 96(1):50-8. Azadani AN, Chitsaz S, Mannion A, Mookhoek A, Wisneski A, Guccione JM, Hope MD, Ge L, Tseng EE. PMID: 23731613.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    73. Evaluation of Marfan patients status post valve-sparing aortic root replacement with 4D flow. Magn Reson Imaging. 2013 Nov; 31(9):1479-84. Hope TA, Kvitting JP, Hope MD, Miller DC, Markl M, Herfkens RJ. PMID: 23706513.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    74. Clinical Applications of Aortic 4D Flow Imaging. Curr Cardiovasc Imaging Rep. 2013; 6(2):128-39. Hope MD, Wrenn SJ, Dyverfeldt P.
    75. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis. JACC Cardiovasc Imaging. 2013 Jan; 6(1):64-71. Dyverfeldt P, Hope MD, Tseng EE, Saloner D. PMID: 23328563.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    76. 4D flow MRI. J Magn Reson Imaging. 2012 Nov; 36(5):1015-36. Markl M, Frydrychowicz A, Kozerke S, Hope M, Wieben O. PMID: 23090914.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    77. Quantitative assessment of asymmetric aortic dilation with valve-related aortic disease. Acad Radiol. 2013 Jan; 20(1):10-5. Lu MT, Thadani SR, Hope MD. PMID: 22951111.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    78. Imaging biomarkers of aortic disease: increased growth rates with eccentric systolic flow. J Am Coll Cardiol. 2012 Jul 24; 60(4):356-7. Hope MD, Wrenn J, Sigovan M, Foster E, Tseng EE, Saloner D. PMID: 22813616.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    79. Re: bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jun; 67(6):618; author reply 618. Yildiz S, Boyaci N, Karakas O, Karakas E, Cece H. PMID: 22526059.
      View in: PubMed   Mentions:    Fields:    
    80. Correlation of calcification on excised aortic valves by micro-computed tomography with severity of aortic stenosis. J Heart Valve Dis. 2012 May; 21(3):320-7. Chitsaz S, Gundiah N, Blackshear C, Tegegn N, Yan KS, Azadani AN, Hope M, Tseng EE. PMID: 22808832.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    81. Dynamic evaluation of a quadricuspid aortic valve with coronary computed tomography angiography. J Thorac Imaging. 2012 May; 27(3):W46-7. Cannavale G, Hope MD, Crook SE, Elicker BM. PMID: 21873907.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    82. Comparison of liver transplantation outcomes from adult split liver and circulatory death donors. Br J Surg. 2012 Jun; 99(6):839-47. Mallik M, Callaghan CJ, Hope M, Gibbs P, Davies S, Gimson AE, Griffiths WJ, Pettigrew GJ. PMID: 22511247.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    83. Improved risk assessment for abdominal aortic aneurysm rupture: off-the-wall imaging. J Am Coll Cardiol. 2011 Dec 06; 58(24):2531-2. Hope TA, Hope MD. PMID: 22133854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    84. Incidental aortic valve calcification on CT scans: significance for bicuspid and tricuspid valve disease. Acad Radiol. 2012 May; 19(5):542-7. Hope MD, Urbania TH, Yu JP, Chitsaz S, Tseng E. PMID: 22104287.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    85. Bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jan; 67(1):28-31. Malone CD, Urbania TH, Crook SE, Hope MD. PMID: 22070947.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    86. Impaired regional left ventricular strain after repair of tetralogy of Fallot. J Magn Reson Imaging. 2012 Jan; 35(1):79-85. Ordovas KG, Carlsson M, Lease KE, Foster E, Meadows AK, Martin AJ, Hope M, Do L, Higgins CB, Saeed M. PMID: 22002841.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    87. Comparison of four-dimensional flow parameters for quantification of flow eccentricity in the ascending aorta. J Magn Reson Imaging. 2011 Nov; 34(5):1226-30. Sigovan M, Hope MD, Dyverfeldt P, Saloner D. PMID: 21928387.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    88. Post-stenotic dilation: evaluation of ascending aortic dilation with 4D flow MR imaging. Int J Cardiol. 2012 Apr 19; 156(2):e40-2. Hope MD, Dyverfeldt P, Acevedo-Bolton G, Wrenn J, Foster E, Tseng E, Saloner D. PMID: 21907425.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    89. Prediction of hemodynamic severity of coarctation by magnetic resonance imaging. Am J Cardiol. 2011 Nov 01; 108(9):1335-40. Muzzarelli S, Meadows AK, Ordovas KG, Hope MD, Higgins CB, Nielsen JC, Geva T, Meadows JJ. PMID: 21861960.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    90. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7. Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins CB. PMID: 21757170.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    91. Arch hypoplasia and aneurysm after aortic coarctation repair: abnormal flow may be the link. JACC Cardiovasc Imaging. 2011 Jun; 4(6):685-6. Crook SE, Hope MD. PMID: 21679905.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    92. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta. J Magn Reson Imaging. 2011 Jun; 33(6):1440-6. Muzzarelli S, Ordovas KG, Hope MD, Meadows JJ, Higgins CB, Meadows AK. PMID: 21591014.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    93. Helical-shaped streamlines do not represent helical flow. Radiology. 2010 Dec; 257(3):895-6; author reply 896. Bogren HG, Buonocore MH. PMID: 21084422.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    94. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8. Hope MD, Hope TA, Urbania TH, Higgins CB. PMID: 21081744.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    95. Aortopathy in bicuspid aortic valve disease: is it really congenital? Radiology. 2010 Sep; 256(3):1015-6; author reply 1016. Girdauskas E, Borger MA, Kuntze T, Hope MD. PMID: 20720087.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    96. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61. Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB. PMID: 20308444.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    97. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8. Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins CB. PMID: 20187217.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    98. Evaluation of intracranial stenoses and aneurysms with accelerated 4D flow. Magn Reson Imaging. 2010 Jan; 28(1):41-6. Hope TA, Hope MD, Purcell DD, von Morze C, Vigneron DB, Alley MT, Dillon WP. PMID: 19577400.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    99. Role of computed tomography in the evaluation of acute chest pain. J Cardiovasc Comput Tomogr. 2009 Jan-Feb; 3(1 Suppl):S13-22. Urbania TH, Hope MD, Huffaker SD, Reddy GP. PMID: 19203744.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    100. Complete intracranial arterial and venous blood flow evaluation with 4D flow MR imaging. AJNR Am J Neuroradiol. 2009 Feb; 30(2):362-6. Hope MD, Purcell DD, Hope TA, von Morze C, Vigneron DB, Alley MT, Dillon WP. PMID: 18653687.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    101. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9. Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins CB. PMID: 18506021.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    102. Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J Comput Assist Tomogr. 2004 Jul-Aug; 28(4):459-68. Markl M, Draney MT, Hope MD, Levin JM, Chan FP, Alley MT, Pelc NJ, Herfkens RJ. PMID: 15232376.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    103. Images in cardiovascular medicine. Four-dimensional magnetic resonance velocity mapping in a healthy volunteer with pseudocoarctation of the thoracic aorta. Circulation. 2004 Jun 29; 109(25):3221-2. Hope MD, Levin JM, Markl M, Draney MT, Alley M, Herfkens RJ. PMID: 15226232.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    104. Everyday amnesia. The curious effects of a common drug. Pharos Alpha Omega Alpha Honor Med Soc. 2004; 67(1):18-21. Hope MD. PMID: 15065445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    105. A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. J Am Soc Echocardiogr. 2003 Aug; 16(8):824-31. Hope MD, de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN. PMID: 12878991.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    106. MSJAMA. Pain and forgetting. JAMA. 2003 Feb 05; 289(5):617. Hope MD. PMID: 12578502.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    107. Linkage mapping of the interleukin 1beta converting enzyme (Il1bc) and the glutamate receptor subunit KA1 (Grik4) genes to rat chromosome 8. Folia Biol (Praha). 1998; 44(3):107-9. Pravenec M, Kren V, Hope M, Wang JM, St Lezin E. PMID: 10730851.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
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